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The map label for this gene is bioD [H]

Identifier: 108759849

GI number: 108759849

Start: 1471419

End: 1472102

Strand: Direct

Name: bioD [H]

Synonym: MXAN_1259

Alternate gene names: 108759849

Gene position: 1471419-1472102 (Clockwise)

Preceding gene: 108759040

Following gene: 108761051

Centisome position: 16.1

GC content: 74.42

Gene sequence:

>684_bases
GTGGCTGAGCGTGGCAAGCCGTTCCAGATTTTCGTGACGGGCACGGACACCGGCGTGGGGAAGACGCAGGCGTCGTGCGC
GCTCCTGTCGCTGCTGGCGGACGCGGGGCTGCGGCCCCAGGGCTTCAAGCCCTACGAGAGCGGCTGCGCGTCCCTGCGTG
CACCCGCGGACGCGCTGGCCCTGCGCGCGGCGGCGGGCAGCTCGCTGAGCGTGGATGAAGTGTGTCCTCACCGCTTCCGC
CTGCCCGTGGCCCCCGGCGTGGCCGCCAGCCGCCTGGGACGCGAGCCCGACTGGGACGTCACGCTGGCCGCGTGGCGTCG
GCTGTGCGGGGGCAACGCCGTGGTGGAGGGGGCAGGGGGCCTGTTCGTGCCGCTGGACTCGAAGCACGACGTCATCGACC
TCATTGCCACCTTGCGCCTGCCGGTGCTGCTGGTGGCGCGCGCGGGCCTGGGCACGCTCAACCACGCCGCGCTGTCGCTC
CAGGCGCTGGCCGCGCGCCGCATTCCCGTGCGGGCCGTGCTGCTGTCGCGCGGGACGTCCGCGAAGGATGTTTCGGAGCG
CGACAACCGGCGGCTCCTGGAGTCGCGGCACGGCGTCCCGGTGCTGGGACCGGTGCCCTATCTTCCCGACGCGCGGCGCC
GCCATGCCGCGTTTCGCCGCGCGCTGCGGCCGTTGCTGCCCTGA

Upstream 100 bases:

>100_bases
CCCGAGGGCACCAGCCGCCTGCGCTTCTGCCTGTCCGCTTCCCACACCGTGGGCCACGTGGACCTGGCGCTGGAGGCGCT
GCGCAGCGTGGGAGTCCGCC

Downstream 100 bases:

>100_bases
ACGCGCGGAGGCCGGAAAATCGGCCTCCGGCGCGTTTCCTTCCGAGGGCGAGTGCTACAGGTTGCGCAAGTTTTCGGGAC
ATCCGGCCGTGAAATGGACG

Product: dethiobiotin synthase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MAERGKPFQIFVTGTDTGVGKTQASCALLSLLADAGLRPQGFKPYESGCASLRAPADALALRAAAGSSLSVDEVCPHRFR
LPVAPGVAASRLGREPDWDVTLAAWRRLCGGNAVVEGAGGLFVPLDSKHDVIDLIATLRLPVLLVARAGLGTLNHAALSL
QALAARRIPVRAVLLSRGTSAKDVSERDNRRLLESRHGVPVLGPVPYLPDARRRHAAFRRALRPLLP

Sequences:

>Translated_227_residues
MAERGKPFQIFVTGTDTGVGKTQASCALLSLLADAGLRPQGFKPYESGCASLRAPADALALRAAAGSSLSVDEVCPHRFR
LPVAPGVAASRLGREPDWDVTLAAWRRLCGGNAVVEGAGGLFVPLDSKHDVIDLIATLRLPVLLVARAGLGTLNHAALSL
QALAARRIPVRAVLLSRGTSAKDVSERDNRRLLESRHGVPVLGPVPYLPDARRRHAAFRRALRPLLP
>Mature_226_residues
AERGKPFQIFVTGTDTGVGKTQASCALLSLLADAGLRPQGFKPYESGCASLRAPADALALRAAAGSSLSVDEVCPHRFRL
PVAPGVAASRLGREPDWDVTLAAWRRLCGGNAVVEGAGGLFVPLDSKHDVIDLIATLRLPVLLVARAGLGTLNHAALSLQ
ALAARRIPVRAVLLSRGTSAKDVSERDNRRLLESRHGVPVLGPVPYLPDARRRHAAFRRALRPLLP

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=213, Percent_Identity=37.0892018779343, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI87081944, Length=224, Percent_Identity=28.125, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 24091; Mature: 23960

Theoretical pI: Translated: 11.26; Mature: 11.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAERGKPFQIFVTGTDTGVGKTQASCALLSLLADAGLRPQGFKPYESGCASLRAPADALA
CCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHH
LRAAAGSSLSVDEVCPHRFRLPVAPGVAASRLGREPDWDVTLAAWRRLCGGNAVVEGAGG
HHHHCCCCCCHHHHCCCCEECCCCCCHHHHHCCCCCCCCCHHHHHHHHHCCCEEEECCCC
LFVPLDSKHDVIDLIATLRLPVLLVARAGLGTLNHAALSLQALAARRIPVRAVLLSRGTS
EEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCC
AKDVSERDNRRLLESRHGVPVLGPVPYLPDARRRHAAFRRALRPLLP
CCHHHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AERGKPFQIFVTGTDTGVGKTQASCALLSLLADAGLRPQGFKPYESGCASLRAPADALA
CCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHH
LRAAAGSSLSVDEVCPHRFRLPVAPGVAASRLGREPDWDVTLAAWRRLCGGNAVVEGAGG
HHHHCCCCCCHHHHCCCCEECCCCCCHHHHHCCCCCCCCCHHHHHHHHHCCCEEEECCCC
LFVPLDSKHDVIDLIATLRLPVLLVARAGLGTLNHAALSLQALAARRIPVRAVLLSRGTS
EEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCC
AKDVSERDNRRLLESRHGVPVLGPVPYLPDARRRHAAFRRALRPLLP
CCHHHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA