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The map label for this gene is mmgB [H]

Identifier: 108759829

GI number: 108759829

Start: 2520551

End: 2521516

Strand: Reverse

Name: mmgB [H]

Synonym: MXAN_2179

Alternate gene names: 108759829

Gene position: 2521516-2520551 (Counterclockwise)

Preceding gene: 108757025

Following gene: 108760512

Centisome position: 27.59

GC content: 71.01

Gene sequence:

>966_bases
ATGACACACAAGCGGCTGAAGAGGATTGGCATGGTGGGCGGGGGCGCCATGGGGTGCGGTATCGCGCTCGAGCTCGCCAT
CGCCGGCAGGCAGGTGGTGCTCTACAACACGCGCGCCGACAGCAGCGAGCGGGCACGCGCGAAGCTGGAGCGAGACGCAT
CGCTGCTGGTGGAGACGGGCCTGCTCGCCCCGGAGCAGGCTCCCGCCGCGATCGGACGCATCCGCCGCACCACAGTGCTC
GCCGAGGCCGCCGTGGAGCAGGACCTGGTCATCGAGTCCATCCCCGAGGACCTCGCCCTCAAGCAGCAGCTCTTCCGCGA
GCTGGACCAGCTCGCGGCCCCCGACACACTGCTCGCCACCAACACCACCGCGCTGAGCGTGACGGCCATCGCTCGGGACT
GCACGCGGCCGGAGCGCGTCCTCTCTGCCCACTACTATCTGCCCGCGCACCTCATCCCGCTGGTGGACATCATTCCCGGC
GAGAAGACGTCCCCCGACGCGGTGGAGACGGTGCGGCGGTTCATTGAGGAGCTTGGCAAGTCGCCGGTGGTGTTCTCCAG
GGACGTGCCGGGCTCGGTGGGTCCGCGCCTGCAGCAGGCCCTCATCGGCGAGGCCATCCGGCTGGTGCACGAGGGCGTGG
CCACGCCGGAGATGGTGGACCGCGTGCTCACCCAGGGCGTCGGACGGCGCCTGGGCGCTTCGGGTGTCTTCGACCGGCTG
GACCTGGTGGGGTTGGACTTCATGACGGCCCTCCTCCGCGGCACCGGCCGCCCCGTGCCGCCCGTGCTCGCGCAGAAGGT
GGAGCGGGGCGAGCTGGGCCAGAAGACGGGCCAGGGCTTCTACTCCTGGACGCCCGAGTCCACCGCTGCCTACGAGGAGC
GCATGGCCCGCCACCTCGCCACCCAGCTTCGTGAGGATCGGGCAGCGGGCCGCCTCCGCACTCCCATGGCGGAGCTGGCG
GAATGA

Upstream 100 bases:

>100_bases
CCGGCATGGCCCGGTGCATCAATCACACATGCGCCATGAACAATTACAGCAACACATCAAGAGGTTGTCTCTGTCGCGCG
GGCTGGCAAGGCTGTGCCCC

Downstream 100 bases:

>100_bases
GGACGGAGACCGTCCTGCTGGATTCGGCGGTGCTGTCAGACTTCCTGGTGGACGCCATCCGCGAGTACACCACGTGCACC
CCGGAGCTCCCGCCCCGGAG

Product: putative 3-hydroxyacyl-CoA dehydrogenase

Products: NA

Alternate protein names: Beta-hydroxybutyryl-CoA dehydrogenase; BHBD [H]

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MTHKRLKRIGMVGGGAMGCGIALELAIAGRQVVLYNTRADSSERARAKLERDASLLVETGLLAPEQAPAAIGRIRRTTVL
AEAAVEQDLVIESIPEDLALKQQLFRELDQLAAPDTLLATNTTALSVTAIARDCTRPERVLSAHYYLPAHLIPLVDIIPG
EKTSPDAVETVRRFIEELGKSPVVFSRDVPGSVGPRLQQALIGEAIRLVHEGVATPEMVDRVLTQGVGRRLGASGVFDRL
DLVGLDFMTALLRGTGRPVPPVLAQKVERGELGQKTGQGFYSWTPESTAAYEERMARHLATQLREDRAAGRLRTPMAELA
E

Sequences:

>Translated_321_residues
MTHKRLKRIGMVGGGAMGCGIALELAIAGRQVVLYNTRADSSERARAKLERDASLLVETGLLAPEQAPAAIGRIRRTTVL
AEAAVEQDLVIESIPEDLALKQQLFRELDQLAAPDTLLATNTTALSVTAIARDCTRPERVLSAHYYLPAHLIPLVDIIPG
EKTSPDAVETVRRFIEELGKSPVVFSRDVPGSVGPRLQQALIGEAIRLVHEGVATPEMVDRVLTQGVGRRLGASGVFDRL
DLVGLDFMTALLRGTGRPVPPVLAQKVERGELGQKTGQGFYSWTPESTAAYEERMARHLATQLREDRAAGRLRTPMAELA
E
>Mature_320_residues
THKRLKRIGMVGGGAMGCGIALELAIAGRQVVLYNTRADSSERARAKLERDASLLVETGLLAPEQAPAAIGRIRRTTVLA
EAAVEQDLVIESIPEDLALKQQLFRELDQLAAPDTLLATNTTALSVTAIARDCTRPERVLSAHYYLPAHLIPLVDIIPGE
KTSPDAVETVRRFIEELGKSPVVFSRDVPGSVGPRLQQALIGEAIRLVHEGVATPEMVDRVLTQGVGRRLGASGVFDRLD
LVGLDFMTALLRGTGRPVPPVLAQKVERGELGQKTGQGFYSWTPESTAAYEERMARHLATQLREDRAAGRLRTPMAELAE

Specific function: Butyrate/butanol-producing pathway. Phenylacetic acid aerobic catabolism. [C]

COG id: COG1250

COG function: function code I; 3-hydroxyacyl-CoA dehydrogenase

Gene ontology:

Cell location: Mitochondria or Peroxisomes [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI296179429, Length=291, Percent_Identity=32.9896907216495, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI296179427, Length=308, Percent_Identity=31.1688311688312, Blast_Score=138, Evalue=6e-33,
Organism=Homo sapiens, GI68989263, Length=299, Percent_Identity=33.1103678929766, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI261878539, Length=299, Percent_Identity=33.1103678929766, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI20127408, Length=290, Percent_Identity=29.6551724137931, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI115430219, Length=236, Percent_Identity=29.2372881355932, Blast_Score=112, Evalue=3e-25,
Organism=Escherichia coli, GI1787661, Length=293, Percent_Identity=33.4470989761092, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1788682, Length=206, Percent_Identity=33.9805825242718, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790281, Length=247, Percent_Identity=27.1255060728745, Blast_Score=93, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71985923, Length=282, Percent_Identity=27.6595744680851, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17553560, Length=292, Percent_Identity=27.0547945205479, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17549919, Length=297, Percent_Identity=27.6094276094276, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17563036, Length=291, Percent_Identity=27.4914089347079, Blast_Score=114, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI71985930, Length=290, Percent_Identity=25.5172413793103, Blast_Score=111, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI25144276, Length=286, Percent_Identity=29.020979020979, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17508953, Length=286, Percent_Identity=29.020979020979, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17508951, Length=286, Percent_Identity=29.020979020979, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17558304, Length=294, Percent_Identity=28.9115646258503, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI115533614, Length=245, Percent_Identity=29.3877551020408, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI193203623, Length=241, Percent_Identity=28.6307053941909, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI20129993, Length=233, Percent_Identity=34.3347639484979, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI45549573, Length=230, Percent_Identity=31.7391304347826, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI19921000, Length=283, Percent_Identity=27.9151943462898, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24583077, Length=283, Percent_Identity=27.9151943462898, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24583079, Length=283, Percent_Identity=27.9151943462898, Blast_Score=101, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022694
- InterPro:   IPR006180
- InterPro:   IPR006176
- InterPro:   IPR006108
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00725 3HCDH; PF02737 3HCDH_N [H]

EC number: =1.1.1.157 [H]

Molecular weight: Translated: 34820; Mature: 34688

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHKRLKRIGMVGGGAMGCGIALELAIAGRQVVLYNTRADSSERARAKLERDASLLVETG
CCHHHHHHHCCCCCCHHHHHHHHHHEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHC
LLAPEQAPAAIGRIRRTTVLAEAAVEQDLVIESIPEDLALKQQLFRELDQLAAPDTLLAT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEC
NTTALSVTAIARDCTRPERVLSAHYYLPAHLIPLVDIIPGEKTSPDAVETVRRFIEELGK
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCC
SPVVFSRDVPGSVGPRLQQALIGEAIRLVHEGVATPEMVDRVLTQGVGRRLGASGVFDRL
CCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHH
DLVGLDFMTALLRGTGRPVPPVLAQKVERGELGQKTGQGFYSWTPESTAAYEERMARHLA
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHCCCCEEECCCHHHHHHHHHHHHHH
TQLREDRAAGRLRTPMAELAE
HHHHHHHHCCHHCCCHHHHCC
>Mature Secondary Structure 
THKRLKRIGMVGGGAMGCGIALELAIAGRQVVLYNTRADSSERARAKLERDASLLVETG
CHHHHHHHCCCCCCHHHHHHHHHHEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHC
LLAPEQAPAAIGRIRRTTVLAEAAVEQDLVIESIPEDLALKQQLFRELDQLAAPDTLLAT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEC
NTTALSVTAIARDCTRPERVLSAHYYLPAHLIPLVDIIPGEKTSPDAVETVRRFIEELGK
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCC
SPVVFSRDVPGSVGPRLQQALIGEAIRLVHEGVATPEMVDRVLTQGVGRRLGASGVFDRL
CCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHH
DLVGLDFMTALLRGTGRPVPPVLAQKVERGELGQKTGQGFYSWTPESTAAYEERMARHLA
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHCCCCEEECCCHHHHHHHHHHHHHH
TQLREDRAAGRLRTPMAELAE
HHHHHHHHCCHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]