Click here to switch to the map view.

The map label for this gene is infC

Identifier: 108759780

GI number: 108759780

Start: 664395

End: 665138

Strand: Direct

Name: infC

Synonym: MXAN_0581

Alternate gene names: 108759780

Gene position: 664395-665138 (Clockwise)

Preceding gene: 108760224

Following gene: 108761586

Centisome position: 7.27

GC content: 66.94

Gene sequence:

>744_bases
ATCATTCGCGAACAGAGAAGCAGCCGCGGCGGGAGCCGCGACCAGAGAACCAACCGTCGCATCCGTGCCCGTGAGGTCCG
CGTCGTCGGGTCTGACGGTAGCCAGCTCGGGGTCATGCCTCTCGAGGCGGCCCTGGACCGTGCCCGGACCGAGGGGCTGG
ACCTCGTTGAAATCAGCCCCATGGCCAGTCCTCCGGTCTGCAAGATCATGGACTACGGCAAGTTCAAGTACGAGGAGAAG
AAGAAGGCCTCGGAAGCGAAGCGTGCCCAGGTCACGGTCCTGCTCAAGGAAGTGAAGCTCCGTCCGAAGACGGAAGAGCA
CGACTACGAGTTCAAGGTCCGCAATACCCGCCGGTTCATCGAGGACGGGAACAAGGCGAAGGTCGTCATCCAGTTCCGCG
GGCGTGAAATCACGCACAGGGAGCAGGGAACGGCCATCCTCGACGACGTGGCCAAGGACCTGAAGGACGTGGCCGTCGTG
GAGCAGATGCCCCGCATGGAAGGGCGTCTGATGTTCATGATCCTCGCGCCCACGCCGAAGGTGGCGCAGAAGGCCCGCGA
GCTGGTTCGTCAGGCCGCCACCGCCGCCAAGCGGCCCCCGCCGCCGGGAGCCCCGGGCGCGGGCAAGTCGGCCGCCGGTG
CCAGCAGTGGCGCCGAGGAGAAGGCCGAGGAGACGGCCGAGGAAAAGAAGGAAGCGCAGGCCGCGCCGGCAGCAGCCGAG
GCGCAGAGCCCGACGGCGTCCTGA

Upstream 100 bases:

>100_bases
CGGGGCGCTTCACATATGTGTACGGTCCCTTGTTGTCGCGGACCTGCCTGCCACACCTTTGGGGGGGCAGGCCTGAAACC
CAATTCGGAGGAGAGTCACC

Downstream 100 bases:

>100_bases
AGGATTGCCGCCACGCGGTGGGTCTGGGTTCCCACCGCGTGCGGCGCCTCTCGAAAGTTGGGAAGGTGTGGCCGCCGCCA
CACGGGCAGGCAGCCAGGCG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MIREQRSSRGGSRDQRTNRRIRAREVRVVGSDGSQLGVMPLEAALDRARTEGLDLVEISPMASPPVCKIMDYGKFKYEEK
KKASEAKRAQVTVLLKEVKLRPKTEEHDYEFKVRNTRRFIEDGNKAKVVIQFRGREITHREQGTAILDDVAKDLKDVAVV
EQMPRMEGRLMFMILAPTPKVAQKARELVRQAATAAKRPPPPGAPGAGKSAAGASSGAEEKAEETAEEKKEAQAAPAAAE
AQSPTAS

Sequences:

>Translated_247_residues
MIREQRSSRGGSRDQRTNRRIRAREVRVVGSDGSQLGVMPLEAALDRARTEGLDLVEISPMASPPVCKIMDYGKFKYEEK
KKASEAKRAQVTVLLKEVKLRPKTEEHDYEFKVRNTRRFIEDGNKAKVVIQFRGREITHREQGTAILDDVAKDLKDVAVV
EQMPRMEGRLMFMILAPTPKVAQKARELVRQAATAAKRPPPPGAPGAGKSAAGASSGAEEKAEETAEEKKEAQAAPAAAE
AQSPTAS
>Mature_247_residues
MIREQRSSRGGSRDQRTNRRIRAREVRVVGSDGSQLGVMPLEAALDRARTEGLDLVEISPMASPPVCKIMDYGKFKYEEK
KKASEAKRAQVTVLLKEVKLRPKTEEHDYEFKVRNTRRFIEDGNKAKVVIQFRGREITHREQGTAILDDVAKDLKDVAVV
EQMPRMEGRLMFMILAPTPKVAQKARELVRQAATAAKRPPPPGAPGAGKSAAGASSGAEEKAEETAEEKKEAQAAPAAAE
AQSPTAS

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=178, Percent_Identity=50.561797752809, Blast_Score=171, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_MYXXA (P48516)

Other databases:

- EMBL:   U04438
- PIR:   A53379
- ProteinModelPortal:   P48516
- SMR:   P48516
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 27145; Mature: 27145

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIREQRSSRGGSRDQRTNRRIRAREVRVVGSDGSQLGVMPLEAALDRARTEGLDLVEISP
CCCCCCCCCCCCCHHHHHHHHEEEEEEEECCCCCEECCCHHHHHHHHHHHCCCCEEEECC
MASPPVCKIMDYGKFKYEEKKKASEAKRAQVTVLLKEVKLRPKTEEHDYEFKVRNTRRFI
CCCCCCEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHH
EDGNKAKVVIQFRGREITHREQGTAILDDVAKDLKDVAVVEQMPRMEGRLMFMILAPTPK
HCCCCEEEEEEECCCCCCCHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHH
VAQKARELVRQAATAAKRPPPPGAPGAGKSAAGASSGAEEKAEETAEEKKEAQAAPAAAE
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHC
AQSPTAS
CCCCCCC
>Mature Secondary Structure
MIREQRSSRGGSRDQRTNRRIRAREVRVVGSDGSQLGVMPLEAALDRARTEGLDLVEISP
CCCCCCCCCCCCCHHHHHHHHEEEEEEEECCCCCEECCCHHHHHHHHHHHCCCCEEEECC
MASPPVCKIMDYGKFKYEEKKKASEAKRAQVTVLLKEVKLRPKTEEHDYEFKVRNTRRFI
CCCCCCEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHH
EDGNKAKVVIQFRGREITHREQGTAILDDVAKDLKDVAVVEQMPRMEGRLMFMILAPTPK
HCCCCEEEEEEECCCCCCCHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHH
VAQKARELVRQAATAAKRPPPPGAPGAGKSAAGASSGAEEKAEETAEEKKEAQAAPAAAE
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHC
AQSPTAS
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8113184; 8113185; 2544552