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The map label for this gene is topA [H]

Identifier: 108759770

GI number: 108759770

Start: 3523639

End: 3527367

Strand: Direct

Name: topA [H]

Synonym: MXAN_3002

Alternate gene names: 108759770

Gene position: 3523639-3527367 (Clockwise)

Preceding gene: 108759494

Following gene: 108758311

Centisome position: 38.55

GC content: 67.66

Gene sequence:

>3729_bases
GTGGGTATCGAGCGGGGGACGGGTATGGCGGACGCTGAGACGGACATCCTCACGGCGGAGCAGCAGGCATGCCTCGCGCT
CTGGGCCGTTCCCGGCCTGGGGCCGAGGACGCTGGTCGCCCTGCGCGCGTTCGCGGACGGAAGCCTCGCGCCGCTCGCCG
CGACTCCAGTGCGAGACTGGGTGTCCCAGGCGCCGGTTTCCTCACAGGTTCGTCGCAAGCTCGCCTCCGTAGAGCGCCTG
GCGCCGGTGGCGTGGCGGGTGTGGGAGGCCTGCCGGGCGTCGGGCATGAAGGTGGCGTTCCAGGGGCAGGCGGCCTATCC
AGAGCGGCTGGCGGAGGTGGAGGATGCGCCGCCGGTGCTCTTCTACCGGGGCGTGCCGGGGCTGCCGCGGCGTCGGCTGG
CCATGGTAGGCAGCCGCCATCCGGATCAGGGCTTCCTGCCGTTCGCGCGGCGCTTCGCCCGGCAGGTGGCGGCGTCGGGG
GTGGGGGTGGTGTCAGGGGCGGCGTCGGGGGTGGACCGGGCCTGTCACTGGGGCGCGCTGGATGAGGGGGGAGAGACGTG
GGCCTTCCTGGGGTCCGCCCTGGATGCACTCGACACGGCGCAAGCCCGCCTGCTTCCTCATTTCCTGGACCGAGGGGGCG
TGTTCTTCAGCGAGCTGCCTCCCGGCGTCCGGGCGAGCACCACGACGTTTCCCCGGCGCAACCGGCTCATCTCCGGGGCA
TCCGACGCAGTCTTGGTGCTGAGGGCGGGGAAGGATTCGGGGAGTCTGTATACGGCGGAGGCGGGGCGGGCGCAGGGGCG
GCCGGTATTCGCGATGCCCGGTGACGTACGCCAGGAGGAGGCGGCCGGCTGCAACGCATTGCTGCGGAACGGGGAGGCGG
CGGTTTGCCTGGGCCCGGATGATGTGTGGAGGGTGCTGAAAGTGGACCCTCTGGCGGCGGTTCCTCCTGGGACGATGGGC
TCATGGGAGGACCTCTCCGCGGAAGCGAAGGGGGGCCTTCGCGATGTTGGACCGGGTTCCCCGGAGCTTCGACGAGGTGC
TGGTCGGCAGCACCTTCTCACCGGCGGCGCTCGCCAGCGCGCTGGTGGAGTTGGAATTGACGGGGCTGGTCATCCAGCAC
CCCGGAAGGCTGTACGAGAGAATCTAGGTAGGAGAGTCATGGCCACGCGGACGAAGAAGAAGGTGGAAGAGACTGAGGCG
GCCGAGGAGAAGGCGCCCGCCAAGAAGGCCGCCGCCAAGAAGGCCGCCAAGAAGAAGCCTGCGGCCAAGAAGAAGACCGC
CGCCAAGAAGACGGCGGCCCGCCGCCGCACCAAGAAGGGGGACGAGGACGAACTCCCCACCGTGGAAGCAGACGCGGAGG
AGGAGGCCACGCCCCGTGGCAAGGGCCCGCACTACCTGGTCGTCGTGGAGTCTCCCGCCAAGGCGAAGACCATCAAGAAG
TACCTGGGCTCCGGCTACACGGTGAAGGCCTCCGTGGGCCACGTGAAGGACCTGCCCAAGAGCAAGATGGGCGTCGACGT
GGAGCACGACTTCCAGCCCGAGTACACGGTCATCAAGGGCAAGGAGAAGGTCCTCAACGAGCTCAAGAAGATGGCGAAGT
CGGCCGACCGCGTCTTCCTGGCCACGGACCCCGACCGCGAGGGCGAGGCCATTGCGTGGCACATCAAGGAGGAGCTGGCG
CATCCCGACGCGCTCCGAGTGACCTTCAACGAAATCACCAAGAAGGCCATCCAGGAAGCCATCGCGCAGCCGCGCCAGCT
CAACCAGGACAACTACGACTCGCAGCAGACGCGCCGCATCCTCGACCGGCTGGTGGGGTATCAAATCTCCCCGCTGCTCT
GGAAGAAGGTGCGCCGGGGGCTGTCCGCGGGCCGCGTTCAGTCCGTGGCGGTGCGCCTCATCGTGGAGCGCGAGGACGAA
ATCAAGGCCTTCGTCCCCGAGGAGTACTGGACGCTGGACGCGCTGCTGGAGGGCCCCGCTGGCCCGCCGCCGTTCAAGGC
CAAGCTGTCCAAGCTGGACGGCAAGAAGGTGGAGCTGAAGGAGCGCGTCTTCACGGAGAGCCTGGTCGCCGAGCTCCAGA
CGGCCAGCTTCTCGGTGGCCAAGGTCGACCGCCGCGAGCGCCGCCGCAACGCGCCCGCGCCGTTCATCACCTCCAAGCTC
CAGCAGGAGGCGGCCAACCGGCTGTCCTTCACCGCGAAGAAGACGATGACGCTGGCGCAGCGCCTCTACGAAGGCGTGCC
GCTGGGTGACGAGGGCCAGACGGCGCTCATCACGTACATGCGTACGGACTCCACCCGTCTGTCCGACGACGCGGTGAAGC
AGGTGCGCGAGTTCATCGACGGCAAGTACGGCAAGGACTTCCTGCCCGACGAGCCCATGGTGTACCGCAGCAAGAAGAGC
GCCCAGGACGCGCACGAGGCCATCCGGCCCACGTCGCTGGAGTACCCGCCGGAGCGGGTGAAGCCCTTCTTCGAGGCCAT
GGGCGAGGAGGACATGTACCGCCTCTACGAGCTCATCTGGAAACGCTTCGTCGCGTGTCAGATGAAGCCCGCCGTCTATG
ACCAGACCAGCGCGGACATCGCCGCAGGCCGGGCCACCTTCCGCGCCTCCGGCAGCACGCTGAAGTTCGCCGGCTACCTG
GCGGTCTACGGTGCTGGCCTGACGCCGGAGGAAGAGGCGGAGAAGGAGAAGGCCAAGGCCGCCGGTGACGAGAACGCCGA
GGGCGCCGACGCGGTGGGCGAGCTGCCGGTGCTCAACGACGGTGACGCGCTGAACCTCCAGAAGCTGCTCCACGAGCAGC
ACTTCACCCAGCCGCCCCCGCGCTTCAGCGAGGCCACGCTGGTGAAGGAGCTGGAAGAGCGCGGCATTGGCCGCCCGTCC
ACCTACGCCGCCATTCTCTCCACCATCCAGGACAAGAAGTACGTGGAGAAGCTGGAGGGCCGCTTCCGGCCCACGGACCT
GGGGAACATGACCAACGAGATGCTGGTCAAGCACTTCCCCCACGAGCTGGACGTCACCTTCACGGCGACGATGGAGGAGA
AGCTCGACCAGATCTCCGAGGGCGGCGCCAACTGGAAGTCCGTGCTGCACGACTTCTACGGGCCCTTCAAGGAGACGCTC
GAGAAGGCCGAAGCGGAGATGCGCGACGTCAAGCGGGAGGAGATCAAGACGGACATCCCCTGCGAGAAGTGCGGCAACCT
CTTCGTCATCAAGTTCGGGAAGATGGGGCACTTCCTCGCGTGCTCGAACTACCCGGACTGCAAGAACACGAAGGACTTCA
AGCGGGACGCCGAGGGCAAGATCGTCATGGTGGAGGAGGAGACCACCGACGAGGTTTGCGAGAAGTGCACCAAGCCCATG
GTCATCAAGCGGGGCCGCTTCGGGCGCTTCCTGGCCTGTTCCGGCTACCCGGACTGCAAGACGTCCAAGCCCATCTCCAT
TGGCGTGTCGTGCCCGGAGTGCAAGGAGGGCTACCTGACGGAGCGCCGCAGTGGCCGCGGGAAGATTTTCTTCGGCTGCA
ACCGCTACCCGGACTGCAAGTTCGCTGCCTGGGACCGGCCGCTGGCCGAGCCGTGCCCCACCTGTGCGTCCCCCTACCTG
CTCCAGAAGTTCTCCAAGCGGGACGGCCCGTACGTGGCGTGCCCCAACAAGGAGTGCGACTACCGGCGCGAAATCACCGA
GCAGCCCGGGGGCCCGGGTGGGTCACCCGAAGCCTCCTCGGCTGCTTGA

Upstream 100 bases:

>100_bases
AAATGCAATGGGCCCCTCGGATGGAGGGGCTGAGTGCTTGACCGGTGGCGGTCCGGTGTTTATGTGTCGCGCCCCTCCCA
GCGGCCCCACCTTCATATAG

Downstream 100 bases:

>100_bases
AAGCCCAGTAGTTACATGGGCATGGCCCGTCCTCGGCTTGACAGCCTTGGCGGGCCCGCCCTAGAAGTCCAGGCTGCTCC
CTCCCCGGGAACGTCGAACG

Product: putative DNA protecting protein DprA/DNA topoisomerase I

Products: NA

Alternate protein names: DNA topoisomerase I; Omega-protein; Relaxing enzyme; Swivelase; Untwisting enzyme [H]

Number of amino acids: Translated: 1242; Mature: 1241

Protein sequence:

>1242_residues
MGIERGTGMADAETDILTAEQQACLALWAVPGLGPRTLVALRAFADGSLAPLAATPVRDWVSQAPVSSQVRRKLASVERL
APVAWRVWEACRASGMKVAFQGQAAYPERLAEVEDAPPVLFYRGVPGLPRRRLAMVGSRHPDQGFLPFARRFARQVAASG
VGVVSGAASGVDRACHWGALDEGGETWAFLGSALDALDTAQARLLPHFLDRGGVFFSELPPGVRASTTTFPRRNRLISGA
SDAVLVLRAGKDSGSLYTAEAGRAQGRPVFAMPGDVRQEEAAGCNALLRNGEAAVCLGPDDVWRVLKVDPLAAVPPGTMG
SWEDLSAEAKGGLRDVGPGSPELRRGAGRQHLLTGGARQRAGGVGIDGAGHPAPRKAVRENLGRRVMATRTKKKVEETEA
AEEKAPAKKAAAKKAAKKKPAAKKKTAAKKTAARRRTKKGDEDELPTVEADAEEEATPRGKGPHYLVVVESPAKAKTIKK
YLGSGYTVKASVGHVKDLPKSKMGVDVEHDFQPEYTVIKGKEKVLNELKKMAKSADRVFLATDPDREGEAIAWHIKEELA
HPDALRVTFNEITKKAIQEAIAQPRQLNQDNYDSQQTRRILDRLVGYQISPLLWKKVRRGLSAGRVQSVAVRLIVEREDE
IKAFVPEEYWTLDALLEGPAGPPPFKAKLSKLDGKKVELKERVFTESLVAELQTASFSVAKVDRRERRRNAPAPFITSKL
QQEAANRLSFTAKKTMTLAQRLYEGVPLGDEGQTALITYMRTDSTRLSDDAVKQVREFIDGKYGKDFLPDEPMVYRSKKS
AQDAHEAIRPTSLEYPPERVKPFFEAMGEEDMYRLYELIWKRFVACQMKPAVYDQTSADIAAGRATFRASGSTLKFAGYL
AVYGAGLTPEEEAEKEKAKAAGDENAEGADAVGELPVLNDGDALNLQKLLHEQHFTQPPPRFSEATLVKELEERGIGRPS
TYAAILSTIQDKKYVEKLEGRFRPTDLGNMTNEMLVKHFPHELDVTFTATMEEKLDQISEGGANWKSVLHDFYGPFKETL
EKAEAEMRDVKREEIKTDIPCEKCGNLFVIKFGKMGHFLACSNYPDCKNTKDFKRDAEGKIVMVEEETTDEVCEKCTKPM
VIKRGRFGRFLACSGYPDCKTSKPISIGVSCPECKEGYLTERRSGRGKIFFGCNRYPDCKFAAWDRPLAEPCPTCASPYL
LQKFSKRDGPYVACPNKECDYRREITEQPGGPGGSPEASSAA

Sequences:

>Translated_1242_residues
MGIERGTGMADAETDILTAEQQACLALWAVPGLGPRTLVALRAFADGSLAPLAATPVRDWVSQAPVSSQVRRKLASVERL
APVAWRVWEACRASGMKVAFQGQAAYPERLAEVEDAPPVLFYRGVPGLPRRRLAMVGSRHPDQGFLPFARRFARQVAASG
VGVVSGAASGVDRACHWGALDEGGETWAFLGSALDALDTAQARLLPHFLDRGGVFFSELPPGVRASTTTFPRRNRLISGA
SDAVLVLRAGKDSGSLYTAEAGRAQGRPVFAMPGDVRQEEAAGCNALLRNGEAAVCLGPDDVWRVLKVDPLAAVPPGTMG
SWEDLSAEAKGGLRDVGPGSPELRRGAGRQHLLTGGARQRAGGVGIDGAGHPAPRKAVRENLGRRVMATRTKKKVEETEA
AEEKAPAKKAAAKKAAKKKPAAKKKTAAKKTAARRRTKKGDEDELPTVEADAEEEATPRGKGPHYLVVVESPAKAKTIKK
YLGSGYTVKASVGHVKDLPKSKMGVDVEHDFQPEYTVIKGKEKVLNELKKMAKSADRVFLATDPDREGEAIAWHIKEELA
HPDALRVTFNEITKKAIQEAIAQPRQLNQDNYDSQQTRRILDRLVGYQISPLLWKKVRRGLSAGRVQSVAVRLIVEREDE
IKAFVPEEYWTLDALLEGPAGPPPFKAKLSKLDGKKVELKERVFTESLVAELQTASFSVAKVDRRERRRNAPAPFITSKL
QQEAANRLSFTAKKTMTLAQRLYEGVPLGDEGQTALITYMRTDSTRLSDDAVKQVREFIDGKYGKDFLPDEPMVYRSKKS
AQDAHEAIRPTSLEYPPERVKPFFEAMGEEDMYRLYELIWKRFVACQMKPAVYDQTSADIAAGRATFRASGSTLKFAGYL
AVYGAGLTPEEEAEKEKAKAAGDENAEGADAVGELPVLNDGDALNLQKLLHEQHFTQPPPRFSEATLVKELEERGIGRPS
TYAAILSTIQDKKYVEKLEGRFRPTDLGNMTNEMLVKHFPHELDVTFTATMEEKLDQISEGGANWKSVLHDFYGPFKETL
EKAEAEMRDVKREEIKTDIPCEKCGNLFVIKFGKMGHFLACSNYPDCKNTKDFKRDAEGKIVMVEEETTDEVCEKCTKPM
VIKRGRFGRFLACSGYPDCKTSKPISIGVSCPECKEGYLTERRSGRGKIFFGCNRYPDCKFAAWDRPLAEPCPTCASPYL
LQKFSKRDGPYVACPNKECDYRREITEQPGGPGGSPEASSAA
>Mature_1241_residues
GIERGTGMADAETDILTAEQQACLALWAVPGLGPRTLVALRAFADGSLAPLAATPVRDWVSQAPVSSQVRRKLASVERLA
PVAWRVWEACRASGMKVAFQGQAAYPERLAEVEDAPPVLFYRGVPGLPRRRLAMVGSRHPDQGFLPFARRFARQVAASGV
GVVSGAASGVDRACHWGALDEGGETWAFLGSALDALDTAQARLLPHFLDRGGVFFSELPPGVRASTTTFPRRNRLISGAS
DAVLVLRAGKDSGSLYTAEAGRAQGRPVFAMPGDVRQEEAAGCNALLRNGEAAVCLGPDDVWRVLKVDPLAAVPPGTMGS
WEDLSAEAKGGLRDVGPGSPELRRGAGRQHLLTGGARQRAGGVGIDGAGHPAPRKAVRENLGRRVMATRTKKKVEETEAA
EEKAPAKKAAAKKAAKKKPAAKKKTAAKKTAARRRTKKGDEDELPTVEADAEEEATPRGKGPHYLVVVESPAKAKTIKKY
LGSGYTVKASVGHVKDLPKSKMGVDVEHDFQPEYTVIKGKEKVLNELKKMAKSADRVFLATDPDREGEAIAWHIKEELAH
PDALRVTFNEITKKAIQEAIAQPRQLNQDNYDSQQTRRILDRLVGYQISPLLWKKVRRGLSAGRVQSVAVRLIVEREDEI
KAFVPEEYWTLDALLEGPAGPPPFKAKLSKLDGKKVELKERVFTESLVAELQTASFSVAKVDRRERRRNAPAPFITSKLQ
QEAANRLSFTAKKTMTLAQRLYEGVPLGDEGQTALITYMRTDSTRLSDDAVKQVREFIDGKYGKDFLPDEPMVYRSKKSA
QDAHEAIRPTSLEYPPERVKPFFEAMGEEDMYRLYELIWKRFVACQMKPAVYDQTSADIAAGRATFRASGSTLKFAGYLA
VYGAGLTPEEEAEKEKAKAAGDENAEGADAVGELPVLNDGDALNLQKLLHEQHFTQPPPRFSEATLVKELEERGIGRPST
YAAILSTIQDKKYVEKLEGRFRPTDLGNMTNEMLVKHFPHELDVTFTATMEEKLDQISEGGANWKSVLHDFYGPFKETLE
KAEAEMRDVKREEIKTDIPCEKCGNLFVIKFGKMGHFLACSNYPDCKNTKDFKRDAEGKIVMVEEETTDEVCEKCTKPMV
IKRGRFGRFLACSGYPDCKTSKPISIGVSCPECKEGYLTERRSGRGKIFFGCNRYPDCKFAAWDRPLAEPCPTCASPYLL
QKFSKRDGPYVACPNKECDYRREITEQPGGPGGSPEASSAA

Specific function: The reaction catalyzed by topoisomerases leads to the conversion of one topological isomer of DNA to another [H]

COG id: COG0550

COG function: function code L; Topoisomerase IA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Toprim domain [H]

Homologues:

Organism=Homo sapiens, GI4507635, Length=755, Percent_Identity=22.7814569536424, Blast_Score=119, Evalue=2e-26,
Organism=Homo sapiens, GI10835218, Length=603, Percent_Identity=24.0464344941957, Blast_Score=118, Evalue=4e-26,
Organism=Escherichia coli, GI1787529, Length=810, Percent_Identity=42.2222222222222, Blast_Score=559, Evalue=1e-160,
Organism=Escherichia coli, GI48994931, Length=169, Percent_Identity=40.2366863905325, Blast_Score=143, Evalue=7e-35,
Organism=Escherichia coli, GI48994932, Length=204, Percent_Identity=37.7450980392157, Blast_Score=115, Evalue=2e-26,
Organism=Escherichia coli, GI1788061, Length=668, Percent_Identity=24.5508982035928, Blast_Score=112, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI32563869, Length=621, Percent_Identity=25.2818035426731, Blast_Score=122, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17555378, Length=582, Percent_Identity=23.7113402061856, Blast_Score=107, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6323263, Length=593, Percent_Identity=23.9460370994941, Blast_Score=108, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24585251, Length=767, Percent_Identity=23.4680573663625, Blast_Score=125, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24640096, Length=544, Percent_Identity=24.0808823529412, Blast_Score=110, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003601
- InterPro:   IPR013497
- InterPro:   IPR013824
- InterPro:   IPR013825
- InterPro:   IPR000380
- InterPro:   IPR003602
- InterPro:   IPR013498
- InterPro:   IPR005733
- InterPro:   IPR006171 [H]

Pfam domain/function: PF01131 Topoisom_bac; PF01751 Toprim; PF01396 zf-C4_Topoisom [H]

EC number: =5.99.1.2 [H]

Molecular weight: Translated: 136418; Mature: 136287

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: PS00396 TOPOISOMERASE_I_PROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIERGTGMADAETDILTAEQQACLALWAVPGLGPRTLVALRAFADGSLAPLAATPVRDW
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHH
VSQAPVSSQVRRKLASVERLAPVAWRVWEACRASGMKVAFQGQAAYPERLAEVEDAPPVL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHCCCCCCEE
FYRGVPGLPRRRLAMVGSRHPDQGFLPFARRFARQVAASGVGVVSGAASGVDRACHWGAL
EECCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHCCCCC
DEGGETWAFLGSALDALDTAQARLLPHFLDRGGVFFSELPPGVRASTTTFPRRNRLISGA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHCCCCCCCCCCCCCHHHCCCCCC
SDAVLVLRAGKDSGSLYTAEAGRAQGRPVFAMPGDVRQEEAAGCNALLRNGEAAVCLGPD
CCEEEEEEECCCCCCEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCEEEEECCH
DVWRVLKVDPLAAVPPGTMGSWEDLSAEAKGGLRDVGPGSPELRRGAGRQHLLTGGARQR
HHHHHHEECCCCCCCCCCCCCHHHCCHHHCCCCCCCCCCCHHHHHCCCCHHHHCCCCHHC
AGGVGIDGAGHPAPRKAVRENLGRRVMATRTKKKVEETEAAEEKAPAKKAAAKKAAKKKP
CCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCC
AAKKKTAAKKTAARRRTKKGDEDELPTVEADAEEEATPRGKGPHYLVVVESPAKAKTIKK
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCCCCCEEEEEECCCHHHHHHHH
YLGSGYTVKASVGHVKDLPKSKMGVDVEHDFQPEYTVIKGKEKVLNELKKMAKSADRVFL
HHCCCCEEEECCCHHHHCCHHHCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCEEEE
ATDPDREGEAIAWHIKEELAHPDALRVTFNEITKKAIQEAIAQPRQLNQDNYDSQQTRRI
ECCCCCCCCEEEEEEHHHHCCCCCEEEEHHHHHHHHHHHHHHCHHHCCCCCCCHHHHHHH
LDRLVGYQISPLLWKKVRRGLSAGRVQSVAVRLIVEREDEIKAFVPEEYWTLDALLEGPA
HHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHEECCHHHHHHHHHHCCCC
GPPPFKAKLSKLDGKKVELKERVFTESLVAELQTASFSVAKVDRRERRRNAPAPFITSKL
CCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCHHHHHH
QQEAANRLSFTAKKTMTLAQRLYEGVPLGDEGQTALITYMRTDSTRLSDDAVKQVREFID
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHC
GKYGKDFLPDEPMVYRSKKSAQDAHEAIRPTSLEYPPERVKPFFEAMGEEDMYRLYELIW
CCCCCCCCCCCCHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHH
KRFVACQMKPAVYDQTSADIAAGRATFRASGSTLKFAGYLAVYGAGLTPEEEAEKEKAKA
HHHHHHCCCCHHCCCCCCHHHHCCCEEECCCCEEEHHHHHHHHCCCCCCHHHHHHHHHHH
AGDENAEGADAVGELPVLNDGDALNLQKLLHEQHFTQPPPRFSEATLVKELEERGIGRPS
CCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCH
TYAAILSTIQDKKYVEKLEGRFRPTDLGNMTNEMLVKHFPHELDVTFTATMEEKLDQISE
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHC
GGANWKSVLHDFYGPFKETLEKAEAEMRDVKREEIKTDIPCEKCGNLFVIKFGKMGHFLA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCEEEEEECCCCCEEE
CSNYPDCKNTKDFKRDAEGKIVMVEEETTDEVCEKCTKPMVIKRGRFGRFLACSGYPDCK
ECCCCCCCCCHHHHHCCCCCEEEEECCCHHHHHHHCCCCEEEECCCCCCEEEECCCCCCC
TSKPISIGVSCPECKEGYLTERRSGRGKIFFGCNRYPDCKFAAWDRPLAEPCPTCASPYL
CCCCEEECCCCCHHHCCCHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHH
LQKFSKRDGPYVACPNKECDYRREITEQPGGPGGSPEASSAA
HHHHHCCCCCEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GIERGTGMADAETDILTAEQQACLALWAVPGLGPRTLVALRAFADGSLAPLAATPVRDW
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHH
VSQAPVSSQVRRKLASVERLAPVAWRVWEACRASGMKVAFQGQAAYPERLAEVEDAPPVL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHCCCCCCEE
FYRGVPGLPRRRLAMVGSRHPDQGFLPFARRFARQVAASGVGVVSGAASGVDRACHWGAL
EECCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHCCCCC
DEGGETWAFLGSALDALDTAQARLLPHFLDRGGVFFSELPPGVRASTTTFPRRNRLISGA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHCCCCCCCCCCCCCHHHCCCCCC
SDAVLVLRAGKDSGSLYTAEAGRAQGRPVFAMPGDVRQEEAAGCNALLRNGEAAVCLGPD
CCEEEEEEECCCCCCEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCEEEEECCH
DVWRVLKVDPLAAVPPGTMGSWEDLSAEAKGGLRDVGPGSPELRRGAGRQHLLTGGARQR
HHHHHHEECCCCCCCCCCCCCHHHCCHHHCCCCCCCCCCCHHHHHCCCCHHHHCCCCHHC
AGGVGIDGAGHPAPRKAVRENLGRRVMATRTKKKVEETEAAEEKAPAKKAAAKKAAKKKP
CCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCC
AAKKKTAAKKTAARRRTKKGDEDELPTVEADAEEEATPRGKGPHYLVVVESPAKAKTIKK
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCCCCCEEEEEECCCHHHHHHHH
YLGSGYTVKASVGHVKDLPKSKMGVDVEHDFQPEYTVIKGKEKVLNELKKMAKSADRVFL
HHCCCCEEEECCCHHHHCCHHHCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCEEEE
ATDPDREGEAIAWHIKEELAHPDALRVTFNEITKKAIQEAIAQPRQLNQDNYDSQQTRRI
ECCCCCCCCEEEEEEHHHHCCCCCEEEEHHHHHHHHHHHHHHCHHHCCCCCCCHHHHHHH
LDRLVGYQISPLLWKKVRRGLSAGRVQSVAVRLIVEREDEIKAFVPEEYWTLDALLEGPA
HHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHEECCHHHHHHHHHHCCCC
GPPPFKAKLSKLDGKKVELKERVFTESLVAELQTASFSVAKVDRRERRRNAPAPFITSKL
CCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCHHHHHH
QQEAANRLSFTAKKTMTLAQRLYEGVPLGDEGQTALITYMRTDSTRLSDDAVKQVREFID
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHC
GKYGKDFLPDEPMVYRSKKSAQDAHEAIRPTSLEYPPERVKPFFEAMGEEDMYRLYELIW
CCCCCCCCCCCCHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHH
KRFVACQMKPAVYDQTSADIAAGRATFRASGSTLKFAGYLAVYGAGLTPEEEAEKEKAKA
HHHHHHCCCCHHCCCCCCHHHHCCCEEECCCCEEEHHHHHHHHCCCCCCHHHHHHHHHHH
AGDENAEGADAVGELPVLNDGDALNLQKLLHEQHFTQPPPRFSEATLVKELEERGIGRPS
CCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCH
TYAAILSTIQDKKYVEKLEGRFRPTDLGNMTNEMLVKHFPHELDVTFTATMEEKLDQISE
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHC
GGANWKSVLHDFYGPFKETLEKAEAEMRDVKREEIKTDIPCEKCGNLFVIKFGKMGHFLA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCEEEEEECCCCCEEE
CSNYPDCKNTKDFKRDAEGKIVMVEEETTDEVCEKCTKPMVIKRGRFGRFLACSGYPDCK
ECCCCCCCCCHHHHHCCCCCEEEEECCCHHHHHHHCCCCEEEECCCCCCEEEECCCCCCC
TSKPISIGVSCPECKEGYLTERRSGRGKIFFGCNRYPDCKFAAWDRPLAEPCPTCASPYL
CCCCEEECCCCCHHHCCCHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHH
LQKFSKRDGPYVACPNKECDYRREITEQPGGPGGSPEASSAA
HHHHHCCCCCEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]