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The map label for this gene is kinA [H]

Identifier: 108759722

GI number: 108759722

Start: 108152

End: 110458

Strand: Reverse

Name: kinA [H]

Synonym: MXAN_0095

Alternate gene names: 108759722

Gene position: 110458-108152 (Counterclockwise)

Preceding gene: 108758711

Following gene: 108763737

Centisome position: 1.21

GC content: 68.66

Gene sequence:

>2307_bases
TTGGCTGCGCCCTGGCAACCCAAGGGAAGCATGTCGACAGAGCAGTGGGCCCACCGCTTCTTCGAGCTGTCCACGGAGCC
CTACGTCATCCTGGGCCGTGATGGCGTGTTGCTCGAAGCCAATCCTGCCTTTGGCCACCTGGTGGGCCTGTCTTTGACGT
CACTGCGTGGCATGGCCTTGCAGGATTTCATCCCCATCGAAGATGCCGCCGTCCTGTTCGCGCATCTGGGTTCCACAAGC
CCCACCTCGCGCACCTGCCGTTGGCGCCGGCCGGATGGGTCCTGGCTGCCTCTGTCCTGGCGCATCACCGCCGCTTCGGA
GTCGGAGCCACTCTACTGCACGGTGCAGCGGGCCGAGGAACCATCCGCCGCCCCCTGGCCGGAGAGTGACTACCTGCCCT
TCGGCCTCTACCTGGTCGACATCCGCACGCGCCGGGTCCACTACGTCAACCACCGCTTCTGCCAACTGTGGGGCATCACC
GAGTTGGAGGGCGCCATCCAGCGGGGTGAGTTGTCCCATGACGAGGTGATCCACCATTGCCTCAAGGCTGGCGACGCGGC
GGAGTTCCTGCGCCTGTGCGCGGCCCCGGACCAGGGCTGCGTGCCGGGCCTGGTGGAGGACGAAGCCAGGCTGTCGGATG
GACGCACCCTGCGACGGCTGTCCACGTCCTCCTCGGTCGCGGGGGACGCCATGCGCTACCGGATGTTCGCGTTCGAGGAC
GTCACCGAGAGCAAGCGCACGCAGGAGGCGCTGCGCCGTTCAGAGGAGAGCTTCCGCAGGCTCATCGACCGGGCGCCCGA
AGGCATCTTCGTGCACACCCAGCGGCGCTTCATCTACGCCAACCCCACGCTGCTGCGGGCCCTGGGCTACGACGACCCGG
CCGAGCTGATGGCAAAGCCCATCTGGAGCATCGTCCATCCGGATGACCTGGAGCTCGTGAAGGACCGCGTGCACACCGCG
GCCGTGAAGGGCGCGCTGGCCCCGCTGCGGGAGGTCCGCTACCTGCGGCGCGACGGCACCTGGTACGACGCGGAGAGCGT
GGGCATCCCCATCGAGTTCGACGGACACGAGGCCGTCGTGGTGATGGCGCGCGACATCACCGAGCGCAAGCAGGCCCAGT
CGCAGCTCCTGCAGAACGACCGCATGGTGCTGGCCGGCACGCTGGCGGCGGGCGTGGGGCACGAAATCAACAACCCGCTG
ACCTACGTCATGGCCAACCTGGCCTCGGCCCTGGAGTCCGTGAGCCGCCTGGGCGCGGAGCTGACGCGGGCCGGAGAGCG
CGGTCCCAGCAGCGTGGCGTGGCCCGCGACGCTGCATGACGCGGAGGCCCTGCTGAAGGAGGCGCAAGAAGGCGCCATGC
GCGTGCGCAACATCGTGCGGGACTTGAAGTTCATCTCCCGTCAGGATGAGGAGCGGCGCGAAGCGGTGGACGTGCGGCAG
CCGTTGGACTTCTCCATCAACATGGCCGCCAGCCAACTGCGTCACCGGGCGCGGCTCATCAAGAAGTACGAGTCCGTCCC
CCGCGTGTACGCGGACGGCTCGCGCCTGGGCCAGGTGTTCCTCAACCTGCTGGTGAACTCGGCGCAGGCCATTCCCGAAG
GCAACGCCGAGGAGCACCACATCACCGTGTGGGTCCGCGCCGGACCGCCGGGCAGCGTGCTGGTGGACGTGAGCGACTCC
GGCTGCGGCATGACGCCCGCGGTGCTCTCCCGCGTCTTCGACCCCTTCTTCACCACCAAGCCCGTGGGCAAGGGCACGGG
GCTGGGGCTGTCCATCTGCCACAGCCTCATCCGCAAGCAGGGCGGTGACATCACCGTCCGCAGCGAACTGGGCCAGGGCA
CCACCTTCACCGTCACCCTGCCCACGGCGCCGGACGCCGTCCCGACCCAGGCCGCGCCGGTGGCGCCCGCGCCCCACGCC
GAGCGGCGGGGACAGGTGCTGGTGATTGACGACGAGCCCGCGGTGGGCCGCTCCCTGGCGCGCATCATCGGCATGCGGCA
CCGGGTGACGGTGGTGAACAACGGCGAGGACGCGCTGGCGGTGCTGACATCGGGCGCGCCGTTCGACGCCGTCTTCTGCG
ACCTGATGATGCCGGGCATCTCCGGCATGGACGTCTACGAGCGCGTCCGCGAGCGCGGGGATGGCATCGCCGAGCGCTTC
ATCTTCATCACCGGCGGCTCGTACACCACGCGGGCCCGTCAGTTCCTGGAGCGCGTGCCGAACCTGCAGATTGAGAAGCC
CTTCGACGTGGAGTCGATTCATCAGGGCCTGGGACAACTCCTGGGTGCCTCTCGTGGTAGCGAATGA

Upstream 100 bases:

>100_bases
ACATGCAATTTTTCCACAAATAGTGTCTATGTCCCGGAAAGCGCAAAGGCGTCTACGAACACCTCGCATGCCATGACCCG
GCCTTCCCCCCAAGCCGGCG

Downstream 100 bases:

>100_bases
CGCCGGGCGTCCTCCCGGCCCAACTGTGAAAGGAGTCCTCGGGTGATTGACGGCAACTTCGTCATCGATGCGGTGACACA
CGCCTACAACCTCCATCCCA

Product: sensory box histidine kinase/response regulator

Products: NA

Alternate protein names: Stage II sporulation protein F; Stage II sporulation protein J [H]

Number of amino acids: Translated: 768; Mature: 767

Protein sequence:

>768_residues
MAAPWQPKGSMSTEQWAHRFFELSTEPYVILGRDGVLLEANPAFGHLVGLSLTSLRGMALQDFIPIEDAAVLFAHLGSTS
PTSRTCRWRRPDGSWLPLSWRITAASESEPLYCTVQRAEEPSAAPWPESDYLPFGLYLVDIRTRRVHYVNHRFCQLWGIT
ELEGAIQRGELSHDEVIHHCLKAGDAAEFLRLCAAPDQGCVPGLVEDEARLSDGRTLRRLSTSSSVAGDAMRYRMFAFED
VTESKRTQEALRRSEESFRRLIDRAPEGIFVHTQRRFIYANPTLLRALGYDDPAELMAKPIWSIVHPDDLELVKDRVHTA
AVKGALAPLREVRYLRRDGTWYDAESVGIPIEFDGHEAVVVMARDITERKQAQSQLLQNDRMVLAGTLAAGVGHEINNPL
TYVMANLASALESVSRLGAELTRAGERGPSSVAWPATLHDAEALLKEAQEGAMRVRNIVRDLKFISRQDEERREAVDVRQ
PLDFSINMAASQLRHRARLIKKYESVPRVYADGSRLGQVFLNLLVNSAQAIPEGNAEEHHITVWVRAGPPGSVLVDVSDS
GCGMTPAVLSRVFDPFFTTKPVGKGTGLGLSICHSLIRKQGGDITVRSELGQGTTFTVTLPTAPDAVPTQAAPVAPAPHA
ERRGQVLVIDDEPAVGRSLARIIGMRHRVTVVNNGEDALAVLTSGAPFDAVFCDLMMPGISGMDVYERVRERGDGIAERF
IFITGGSYTTRARQFLERVPNLQIEKPFDVESIHQGLGQLLGASRGSE

Sequences:

>Translated_768_residues
MAAPWQPKGSMSTEQWAHRFFELSTEPYVILGRDGVLLEANPAFGHLVGLSLTSLRGMALQDFIPIEDAAVLFAHLGSTS
PTSRTCRWRRPDGSWLPLSWRITAASESEPLYCTVQRAEEPSAAPWPESDYLPFGLYLVDIRTRRVHYVNHRFCQLWGIT
ELEGAIQRGELSHDEVIHHCLKAGDAAEFLRLCAAPDQGCVPGLVEDEARLSDGRTLRRLSTSSSVAGDAMRYRMFAFED
VTESKRTQEALRRSEESFRRLIDRAPEGIFVHTQRRFIYANPTLLRALGYDDPAELMAKPIWSIVHPDDLELVKDRVHTA
AVKGALAPLREVRYLRRDGTWYDAESVGIPIEFDGHEAVVVMARDITERKQAQSQLLQNDRMVLAGTLAAGVGHEINNPL
TYVMANLASALESVSRLGAELTRAGERGPSSVAWPATLHDAEALLKEAQEGAMRVRNIVRDLKFISRQDEERREAVDVRQ
PLDFSINMAASQLRHRARLIKKYESVPRVYADGSRLGQVFLNLLVNSAQAIPEGNAEEHHITVWVRAGPPGSVLVDVSDS
GCGMTPAVLSRVFDPFFTTKPVGKGTGLGLSICHSLIRKQGGDITVRSELGQGTTFTVTLPTAPDAVPTQAAPVAPAPHA
ERRGQVLVIDDEPAVGRSLARIIGMRHRVTVVNNGEDALAVLTSGAPFDAVFCDLMMPGISGMDVYERVRERGDGIAERF
IFITGGSYTTRARQFLERVPNLQIEKPFDVESIHQGLGQLLGASRGSE
>Mature_767_residues
AAPWQPKGSMSTEQWAHRFFELSTEPYVILGRDGVLLEANPAFGHLVGLSLTSLRGMALQDFIPIEDAAVLFAHLGSTSP
TSRTCRWRRPDGSWLPLSWRITAASESEPLYCTVQRAEEPSAAPWPESDYLPFGLYLVDIRTRRVHYVNHRFCQLWGITE
LEGAIQRGELSHDEVIHHCLKAGDAAEFLRLCAAPDQGCVPGLVEDEARLSDGRTLRRLSTSSSVAGDAMRYRMFAFEDV
TESKRTQEALRRSEESFRRLIDRAPEGIFVHTQRRFIYANPTLLRALGYDDPAELMAKPIWSIVHPDDLELVKDRVHTAA
VKGALAPLREVRYLRRDGTWYDAESVGIPIEFDGHEAVVVMARDITERKQAQSQLLQNDRMVLAGTLAAGVGHEINNPLT
YVMANLASALESVSRLGAELTRAGERGPSSVAWPATLHDAEALLKEAQEGAMRVRNIVRDLKFISRQDEERREAVDVRQP
LDFSINMAASQLRHRARLIKKYESVPRVYADGSRLGQVFLNLLVNSAQAIPEGNAEEHHITVWVRAGPPGSVLVDVSDSG
CGMTPAVLSRVFDPFFTTKPVGKGTGLGLSICHSLIRKQGGDITVRSELGQGTTFTVTLPTAPDAVPTQAAPVAPAPHAE
RRGQVLVIDDEPAVGRSLARIIGMRHRVTVVNNGEDALAVLTSGAPFDAVFCDLMMPGISGMDVYERVRERGDGIAERFI
FITGGSYTTRARQFLERVPNLQIEKPFDVESIHQGLGQLLGASRGSE

Specific function: Phosphorylates the sporulation-regulatory proteins spo0A and spo0F. It also autophosphorylates in the presence of ATP [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=262, Percent_Identity=31.6793893129771, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI48994928, Length=374, Percent_Identity=29.144385026738, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1788549, Length=272, Percent_Identity=28.6764705882353, Blast_Score=105, Evalue=2e-23,
Organism=Escherichia coli, GI87081816, Length=212, Percent_Identity=28.7735849056604, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI145693157, Length=296, Percent_Identity=30.7432432432432, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1790300, Length=267, Percent_Identity=28.0898876404494, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788713, Length=413, Percent_Identity=23.4866828087167, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR013655
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF08447 PAS_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 84750; Mature: 84619

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAPWQPKGSMSTEQWAHRFFELSTEPYVILGRDGVLLEANPAFGHLVGLSLTSLRGMAL
CCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCEEEECCCCHHHHHHHHHHHHCCCHH
QDFIPIEDAAVLFAHLGSTSPTSRTCRWRRPDGSWLPLSWRITAASESEPLYCTVQRAEE
HHCCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEEEEEEECCCCCCEEEEEECCCC
PSAAPWPESDYLPFGLYLVDIRTRRVHYVNHRFCQLWGITELEGAIQRGELSHDEVIHHC
CCCCCCCCCCCCCEEEEEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHH
LKAGDAAEFLRLCAAPDQGCVPGLVEDEARLSDGRTLRRLSTSSSVAGDAMRYRMFAFED
HHCCCHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHH
VTESKRTQEALRRSEESFRRLIDRAPEGIFVHTQRRFIYANPTLLRALGYDDPAELMAKP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEECCHHHHHCCCCCHHHHHHHH
IWSIVHPDDLELVKDRVHTAAVKGALAPLREVRYLRRDGTWYDAESVGIPIEFDGHEAVV
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCEEEECCCCEEE
VMARDITERKQAQSQLLQNDRMVLAGTLAAGVGHEINNPLTYVMANLASALESVSRLGAE
EEEHHHHHHHHHHHHHHHCCCEEEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LTRAGERGPSSVAWPATLHDAEALLKEAQEGAMRVRNIVRDLKFISRQDEERREAVDVRQ
HHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCC
PLDFSINMAASQLRHRARLIKKYESVPRVYADGSRLGQVFLNLLVNSAQAIPEGNAEEHH
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEE
ITVWVRAGPPGSVLVDVSDSGCGMTPAVLSRVFDPFFTTKPVGKGTGLGLSICHSLIRKQ
EEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHCHHHCCCCCCCCCCCHHHHHHHHHHHC
GGDITVRSELGQGTTFTVTLPTAPDAVPTQAAPVAPAPHAERRGQVLVIDDEPAVGRSLA
CCCEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHCCCEEEECCCCHHHHHHH
RIIGMRHRVTVVNNGEDALAVLTSGAPFDAVFCDLMMPGISGMDVYERVRERGDGIAERF
HHHCCCEEEEEEECCCCEEEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEE
IFITGGSYTTRARQFLERVPNLQIEKPFDVESIHQGLGQLLGASRGSE
EEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AAPWQPKGSMSTEQWAHRFFELSTEPYVILGRDGVLLEANPAFGHLVGLSLTSLRGMAL
CCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCEEEECCCCHHHHHHHHHHHHCCCHH
QDFIPIEDAAVLFAHLGSTSPTSRTCRWRRPDGSWLPLSWRITAASESEPLYCTVQRAEE
HHCCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEEEEEEECCCCCCEEEEEECCCC
PSAAPWPESDYLPFGLYLVDIRTRRVHYVNHRFCQLWGITELEGAIQRGELSHDEVIHHC
CCCCCCCCCCCCCEEEEEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHH
LKAGDAAEFLRLCAAPDQGCVPGLVEDEARLSDGRTLRRLSTSSSVAGDAMRYRMFAFED
HHCCCHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHH
VTESKRTQEALRRSEESFRRLIDRAPEGIFVHTQRRFIYANPTLLRALGYDDPAELMAKP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEECCHHHHHCCCCCHHHHHHHH
IWSIVHPDDLELVKDRVHTAAVKGALAPLREVRYLRRDGTWYDAESVGIPIEFDGHEAVV
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCEEEECCCCEEE
VMARDITERKQAQSQLLQNDRMVLAGTLAAGVGHEINNPLTYVMANLASALESVSRLGAE
EEEHHHHHHHHHHHHHHHCCCEEEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LTRAGERGPSSVAWPATLHDAEALLKEAQEGAMRVRNIVRDLKFISRQDEERREAVDVRQ
HHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCC
PLDFSINMAASQLRHRARLIKKYESVPRVYADGSRLGQVFLNLLVNSAQAIPEGNAEEHH
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEE
ITVWVRAGPPGSVLVDVSDSGCGMTPAVLSRVFDPFFTTKPVGKGTGLGLSICHSLIRKQ
EEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHCHHHCCCCCCCCCCCHHHHHHHHHHHC
GGDITVRSELGQGTTFTVTLPTAPDAVPTQAAPVAPAPHAERRGQVLVIDDEPAVGRSLA
CCCEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHCCCEEEECCCCHHHHHHH
RIIGMRHRVTVVNNGEDALAVLTSGAPFDAVFCDLMMPGISGMDVYERVRERGDGIAERF
HHHCCCEEEEEEECCCCEEEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEE
IFITGGSYTTRARQFLERVPNLQIEKPFDVESIHQGLGQLLGASRGSE
EEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2104615; 2509430; 9384377 [H]