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The map label for this gene is engA

Identifier: 108759687

GI number: 108759687

Start: 4483213

End: 4484592

Strand: Direct

Name: engA

Synonym: MXAN_3766

Alternate gene names: 108759687

Gene position: 4483213-4484592 (Clockwise)

Preceding gene: 108763403

Following gene: 108761838

Centisome position: 49.05

GC content: 68.77

Gene sequence:

>1380_bases
ATGAAGCCCCTGGTCGCAATTGTCGGACGCCCCAACGTGGGCAAGAGCACGCTGTTCAATCGGCTGGTGGGCCGGCGCAT
CGCGCTGGTGCAGGACGAGCCCGGCGTGACGCGGGATCGCCACTACGCGGACGCGGAGTGGGAAGGCCGCCAGTTCACCT
TCATCGACACCGGCGGCTTCGTGCCCGGTGACGAGGACCAACTCCTCCAGCAGGTGCGGGAGCAGGCGCAACTGGCCGTG
GACGAGTGTGACGTCATCGTCTTCGTCACCGACGCCCGGGCGGGACTCACCGCCGCGGACGAGGCCGTGGCCAACTACCT
GCGCAAGAGCGGCAAGCCGGTGGTGCTGGCCGCCAACAAGCTGGACAACACGTCCGGGCAGATGCAGGCGCTGGCCGGTG
AGTTCTACCGCCTGGGCCTGGGCGACGTGCAGGCCCTGTCCGCCGAGCATGGCCTGGGCATGCAGGAGCTGTTCGACTCG
GTCGTCGCCAGGCTGCCGCCCAAGGAAGAGGGCGAGGACGCGGAGGCGCCGCCCGACGACGGCATCATCCGCCTGGCCAT
CATCGGCCGGCCCAACGTGGGCAAGAGCACCCTGGTCAACGCCATCCTGAAGGAGAAGCGGGTGGTGGCCAGTGACGTGG
CGGGGACCACGCGGGACCCGGTGGACTCCGAGCTCACGTACAAGGACCGCAAGCTGCTGCTCACCGACACGGCGGGCATC
CGGCGCAAGAAGTCCATTGCCCAGCGCGTGGAGCAGTTCTCCGTCGTGGCCGCGCTCAAGGTGATGGAGCGCAGCGACGT
GGCGGTGCTGCTGATGGACGCCACGGAGCCGGCGGTGGACCAGGACGCCAAGCTTGCGGGCCTGGCCGAGGAGCGGGGCC
GCGCCCTGGTCATCGTGGTGAACAAGTGGGACCTGGTGGGCGCGGACCAGCGCCGGCAGGAGACCTACCGCGAGTCCCTC
AAGCACTCACTCAAGTTCGTGGGCTACGCGCCCATCCTCTTCACCTCCGCGCTGACGGGCTCCAAGGTGGAGAAGGTCGT
GGATGTGGCGACGGAGCTCGCCGACCAGTTCCGCTTCCGGGCGCCCACCCCACAGCTCAACCGGCTGCTGGACCACATGG
TGGACAACCACCCGGCGCCCATCGTCCGGGGCAAGCCGCTGCGCATGTACTACATCGCCCAGGTGGCCGCGGCGCCGCCG
ACCTTCACCATCACCGTGAATCATCCGGACGGCGTTCCGGACATGTACAAGCGGTACATCACCAACCAGCTGCGCAAGAC
GTTCGACCTGCGCGTGCCCATCCGGCTCATCTTCAAGGGCCGGCCCGGGCAGGCCAAGCGCGAGGCCCGCAAGCGGCCTC
AACGCCAGGGGAAGCGCTGA

Upstream 100 bases:

>100_bases
CGGTTGCTGGGCGCGCATGTGTACCTGGACCTTCGCGTCCGCGTGGAGCCGCGCTGGAGCGAGCGCCCCGAAGGCCTCAA
GAAGCTGGGATACGACTGAA

Downstream 100 bases:

>100_bases
GGCGTCAGTGCGTTGACACTCGCGGCGCGCGCTCCATACAGTGCGCCGCTCTTTAAAAGAGGTTTCCAGACGTGGCCGGA
ACCACCAAGACCGAGAAGAT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MKPLVAIVGRPNVGKSTLFNRLVGRRIALVQDEPGVTRDRHYADAEWEGRQFTFIDTGGFVPGDEDQLLQQVREQAQLAV
DECDVIVFVTDARAGLTAADEAVANYLRKSGKPVVLAANKLDNTSGQMQALAGEFYRLGLGDVQALSAEHGLGMQELFDS
VVARLPPKEEGEDAEAPPDDGIIRLAIIGRPNVGKSTLVNAILKEKRVVASDVAGTTRDPVDSELTYKDRKLLLTDTAGI
RRKKSIAQRVEQFSVVAALKVMERSDVAVLLMDATEPAVDQDAKLAGLAEERGRALVIVVNKWDLVGADQRRQETYRESL
KHSLKFVGYAPILFTSALTGSKVEKVVDVATELADQFRFRAPTPQLNRLLDHMVDNHPAPIVRGKPLRMYYIAQVAAAPP
TFTITVNHPDGVPDMYKRYITNQLRKTFDLRVPIRLIFKGRPGQAKREARKRPQRQGKR

Sequences:

>Translated_459_residues
MKPLVAIVGRPNVGKSTLFNRLVGRRIALVQDEPGVTRDRHYADAEWEGRQFTFIDTGGFVPGDEDQLLQQVREQAQLAV
DECDVIVFVTDARAGLTAADEAVANYLRKSGKPVVLAANKLDNTSGQMQALAGEFYRLGLGDVQALSAEHGLGMQELFDS
VVARLPPKEEGEDAEAPPDDGIIRLAIIGRPNVGKSTLVNAILKEKRVVASDVAGTTRDPVDSELTYKDRKLLLTDTAGI
RRKKSIAQRVEQFSVVAALKVMERSDVAVLLMDATEPAVDQDAKLAGLAEERGRALVIVVNKWDLVGADQRRQETYRESL
KHSLKFVGYAPILFTSALTGSKVEKVVDVATELADQFRFRAPTPQLNRLLDHMVDNHPAPIVRGKPLRMYYIAQVAAAPP
TFTITVNHPDGVPDMYKRYITNQLRKTFDLRVPIRLIFKGRPGQAKREARKRPQRQGKR
>Mature_459_residues
MKPLVAIVGRPNVGKSTLFNRLVGRRIALVQDEPGVTRDRHYADAEWEGRQFTFIDTGGFVPGDEDQLLQQVREQAQLAV
DECDVIVFVTDARAGLTAADEAVANYLRKSGKPVVLAANKLDNTSGQMQALAGEFYRLGLGDVQALSAEHGLGMQELFDS
VVARLPPKEEGEDAEAPPDDGIIRLAIIGRPNVGKSTLVNAILKEKRVVASDVAGTTRDPVDSELTYKDRKLLLTDTAGI
RRKKSIAQRVEQFSVVAALKVMERSDVAVLLMDATEPAVDQDAKLAGLAEERGRALVIVVNKWDLVGADQRRQETYRESL
KHSLKFVGYAPILFTSALTGSKVEKVVDVATELADQFRFRAPTPQLNRLLDHMVDNHPAPIVRGKPLRMYYIAQVAAAPP
TFTITVNHPDGVPDMYKRYITNQLRKTFDLRVPIRLIFKGRPGQAKREARKRPQRQGKR

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=484, Percent_Identity=43.595041322314, Blast_Score=347, Evalue=7e-97,
Organism=Escherichia coli, GI1788919, Length=169, Percent_Identity=32.5443786982249, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6323665, Length=173, Percent_Identity=32.9479768786127, Blast_Score=87, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_MYXXD (Q1D5X5)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_631948.1
- ProteinModelPortal:   Q1D5X5
- SMR:   Q1D5X5
- STRING:   Q1D5X5
- GeneID:   4101526
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_3766
- TIGR:   MXAN_3766
- eggNOG:   COG1160
- HOGENOM:   HBG592135
- OMA:   KCEKAFD
- PhylomeDB:   Q1D5X5
- ProtClustDB:   PRK00093
- BioCyc:   MXAN246197:MXAN_3766-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- SMART:   SM00382
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 50815; Mature: 50815

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPLVAIVGRPNVGKSTLFNRLVGRRIALVQDEPGVTRDRHYADAEWEGRQFTFIDTGGF
CCCEEEEECCCCCCHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCC
VPGDEDQLLQQVREQAQLAVDECDVIVFVTDARAGLTAADEAVANYLRKSGKPVVLAANK
CCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEECC
LDNTSGQMQALAGEFYRLGLGDVQALSAEHGLGMQELFDSVVARLPPKEEGEDAEAPPDD
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCC
GIIRLAIIGRPNVGKSTLVNAILKEKRVVASDVAGTTRDPVDSELTYKDRKLLLTDTAGI
CEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCH
RRKKSIAQRVEQFSVVAALKVMERSDVAVLLMDATEPAVDQDAKLAGLAEERGRALVIVV
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHCCHHHCCCEEEEEE
NKWDLVGADQRRQETYRESLKHSLKFVGYAPILFTSALTGSKVEKVVDVATELADQFRFR
ECCCCCCCHHHHHHHHHHHHHHHHHHHEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
APTPQLNRLLDHMVDNHPAPIVRGKPLRMYYIAQVAAAPPTFTITVNHPDGVPDMYKRYI
CCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEHHHCCCCEEEEEEECCCCCHHHHHHHH
TNQLRKTFDLRVPIRLIFKGRPGQAKREARKRPQRQGKR
HHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCHHHCCCC
>Mature Secondary Structure
MKPLVAIVGRPNVGKSTLFNRLVGRRIALVQDEPGVTRDRHYADAEWEGRQFTFIDTGGF
CCCEEEEECCCCCCHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCC
VPGDEDQLLQQVREQAQLAVDECDVIVFVTDARAGLTAADEAVANYLRKSGKPVVLAANK
CCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEECC
LDNTSGQMQALAGEFYRLGLGDVQALSAEHGLGMQELFDSVVARLPPKEEGEDAEAPPDD
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCC
GIIRLAIIGRPNVGKSTLVNAILKEKRVVASDVAGTTRDPVDSELTYKDRKLLLTDTAGI
CEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCH
RRKKSIAQRVEQFSVVAALKVMERSDVAVLLMDATEPAVDQDAKLAGLAEERGRALVIVV
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHCCHHHCCCEEEEEE
NKWDLVGADQRRQETYRESLKHSLKFVGYAPILFTSALTGSKVEKVVDVATELADQFRFR
ECCCCCCCHHHHHHHHHHHHHHHHHHHEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
APTPQLNRLLDHMVDNHPAPIVRGKPLRMYYIAQVAAAPPTFTITVNHPDGVPDMYKRYI
CCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEHHHCCCCEEEEEEECCCCCHHHHHHHH
TNQLRKTFDLRVPIRLIFKGRPGQAKREARKRPQRQGKR
HHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA