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The map label for this gene is leuE [H]

Identifier: 108759657

GI number: 108759657

Start: 6344535

End: 6345170

Strand: Reverse

Name: leuE [H]

Synonym: MXAN_5068

Alternate gene names: 108759657

Gene position: 6345170-6344535 (Counterclockwise)

Preceding gene: 108762920

Following gene: 108758028

Centisome position: 69.42

GC content: 69.18

Gene sequence:

>636_bases
ATGTTCTTCGACCCGACGCGCCTCACGGCCTACTTCCTGGCGGTGCTCGCGCTCATCCTGACGCCCGGGCCGGACACGAT
GTTCGTGCTGGCCCGGAGCATGGGGCAGGGGCGTAAGGCGGGCATCGTCTCCGCGCTGGGCATCTTCGTCGGATGCCTGT
TCCACATCGCCGCGGCGGCGTTCGGGCTGTCGACGTTGCTGGCGACATCGGCGTTGGCCTTCTCCGTGGTGAAGTGGGGT
GGGGCGGCCTACCTCGTGTGGATGGGCGTGCAGATGCTGCGCAGCAAGGACACCGTGGCCGAGGCGGTGCAGGCGCTGCC
ACCCGCTGGCCTGTGGCGCATCTTCCGCGACGGCGTCGTCACCAACGTGCTGAACCCGAAGGTGGCCGTGTTCTTCCTGG
CCTTCCTGCCGCAGTTCGTGGACGCGTCCGCGGGCTCGACAGGGCTCCAGTTCCTGGGGCTCGGGTTGATGTTCTCCGTC
ACGGGCACGTCGTGGCTGGTGCTGCTGGCTGCGTTCGCGGGTGCCTTTGGGGGCTGGATGCGGCGCAATCCGCGCGTGGC
GGCGTGGCAGAAGCGCGTCACGGGTGGCGTGTTCGTCGCACTGGGGGCGCGGTTGGCGTTGCAGCGCCAGGAGTAG

Upstream 100 bases:

>100_bases
CGCGCGCGCCCGTCTGATGCTGCGGGTCGCTTTGCTCGGCGGTCTCCGGCAGGTACGGTGACTGGCAATCGGGGCCAGTC
GTGCCCCCACTGGAGCCGCC

Downstream 100 bases:

>100_bases
GCGTCAGACGAGCGCCTTGATGACCACGTAGAGCACGTAGAGGACCCACGGCACGGCGGCCAGGAGTCCGAGGATTCCGA
GCAGGCCGGCCCAGACGGGG

Product: homoserine/threonine efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MFFDPTRLTAYFLAVLALILTPGPDTMFVLARSMGQGRKAGIVSALGIFVGCLFHIAAAAFGLSTLLATSALAFSVVKWG
GAAYLVWMGVQMLRSKDTVAEAVQALPPAGLWRIFRDGVVTNVLNPKVAVFFLAFLPQFVDASAGSTGLQFLGLGLMFSV
TGTSWLVLLAAFAGAFGGWMRRNPRVAAWQKRVTGGVFVALGARLALQRQE

Sequences:

>Translated_211_residues
MFFDPTRLTAYFLAVLALILTPGPDTMFVLARSMGQGRKAGIVSALGIFVGCLFHIAAAAFGLSTLLATSALAFSVVKWG
GAAYLVWMGVQMLRSKDTVAEAVQALPPAGLWRIFRDGVVTNVLNPKVAVFFLAFLPQFVDASAGSTGLQFLGLGLMFSV
TGTSWLVLLAAFAGAFGGWMRRNPRVAAWQKRVTGGVFVALGARLALQRQE
>Mature_211_residues
MFFDPTRLTAYFLAVLALILTPGPDTMFVLARSMGQGRKAGIVSALGIFVGCLFHIAAAAFGLSTLLATSALAFSVVKWG
GAAYLVWMGVQMLRSKDTVAEAVQALPPAGLWRIFRDGVVTNVLNPKVAVFFLAFLPQFVDASAGSTGLQFLGLGLMFSV
TGTSWLVLLAAFAGAFGGWMRRNPRVAAWQKRVTGGVFVALGARLALQRQE

Specific function: Exporter of leucine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI1788099, Length=199, Percent_Identity=32.1608040201005, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI48994979, Length=202, Percent_Identity=30.6930693069307, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI48994978, Length=205, Percent_Identity=29.7560975609756, Blast_Score=80, Evalue=8e-17,
Organism=Escherichia coli, GI1786522, Length=144, Percent_Identity=30.5555555555556, Blast_Score=74, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22462; Mature: 22462

Theoretical pI: Translated: 11.69; Mature: 11.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFDPTRLTAYFLAVLALILTPGPDTMFVLARSMGQGRKAGIVSALGIFVGCLFHIAAAA
CCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
FGLSTLLATSALAFSVVKWGGAAYLVWMGVQMLRSKDTVAEAVQALPPAGLWRIFRDGVV
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
TNVLNPKVAVFFLAFLPQFVDASAGSTGLQFLGLGLMFSVTGTSWLVLLAAFAGAFGGWM
HHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRNPRVAAWQKRVTGGVFVALGARLALQRQE
HCCCCHHHHHHHHCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFFDPTRLTAYFLAVLALILTPGPDTMFVLARSMGQGRKAGIVSALGIFVGCLFHIAAAA
CCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
FGLSTLLATSALAFSVVKWGGAAYLVWMGVQMLRSKDTVAEAVQALPPAGLWRIFRDGVV
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
TNVLNPKVAVFFLAFLPQFVDASAGSTGLQFLGLGLMFSVTGTSWLVLLAAFAGAFGGWM
HHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRNPRVAAWQKRVTGGVFVALGARLALQRQE
HCCCCHHHHHHHHCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA