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The map label for this gene is 108759558

Identifier: 108759558

GI number: 108759558

Start: 6183994

End: 6185748

Strand: Direct

Name: 108759558

Synonym: MXAN_4942

Alternate gene names: NA

Gene position: 6183994-6185748 (Clockwise)

Preceding gene: 108760560

Following gene: 108759444

Centisome position: 67.66

GC content: 66.55

Gene sequence:

>1755_bases
ATGGCATTTCGTCCCGAGCACTTCGACGCAATCATCGTGGGCTCTGGCTTTGGCGGCTCGGTGATGGCGTACCGACTGGC
AGAGGCCGGCTTGCGCGTGTGCGTTCTGGAACGAGGAAAGGCCTATCCACCTGGCACGTTCCCGCGCAGTCCCTACGACA
TGCGCAACAACTTCTGGGACCCGAGCAAGGGGTTGCACGGCATGTTCAACCTCTGGTCCTTCCGGGGGCTGGGCGGCGTC
GTCTCCTCCGGGCTGGGCGGAGGCTCGCTCATCTACGCCAACGTCATGCTGCGCAAGGACGAGAAGACCTTCGTCCATGA
GCATCCGCAGACCGGCGGTTATGAGTATTGGCCTGTCACCCGTGACGACCTCGAAGAACACTACGACGCCGTCGAGCGGA
TGATGCACGTCCAGCGATTTCCGCTGGCGCACCCTCCCTACGACGCCACGGCAAAGACGCTGGCCATGAAGCTTGCCGCC
GAACGCCTGGGCCGTGCAGCCGACTGGCAGCTTCCTCCGCTGGCCATCACCTTCGCCAACGCCGGGGCGGCGCCCGCGCT
CGGCGAGCCCATTCGCGAGGCGGCGCCGAACCTCTTCGGCCGCATGCGAACCACCTGCCGGCTGTGTGGCGAGTGCGACA
TCGGGTGCAACTACGGCAGCAAGAACACACTCGACTTCACGTACCTGTCCGCTGCGCATCGCGCGGGGGCTGACCTGCGC
ACCCGCGCGGAGGTGAAAGAGTTCTGGCCCGCGGATGGAGGGGGCTACGTGGTTCAGTACGTGGACCATGCCGAGGCCCG
CGAAGGCGAGCGGCGCGAGGTGGCCTCGGACCAACTCCAGCGGGTGACGCTCACCGCGGACCGGCTCGTACTGGGGGCGG
GCACCTTCGGCACCACGTACCTGCTGCTGAAGAACCGGGCGCACTTTCCACGCCTGAGCGCCCGGCTCGGCACACGCTTC
TGCGGCAATGGAGACCTGCTGGGCTTCCTGCTGCGCAGCGTGGACAGCAGCTCCGGGACCCGTCTGCCTCGGGTGCTGGA
TGGCGGAAGAGGCCCCGTCATCACCAGCGCGCTCCACTTCCGTGGCAAGGAGGAGGGCGGCACCGGGCGCGGCTACTACA
TCGAGGACGCGGGCTACCCGGAGTTCATCAACTGGCTCTATGAAGGCTCGCAGCAGGCCCCCCTTCTGAGGCGAGGCATG
CGCCTGGCCTGGCGCCTCGTCAAGGGCTGGATCGGCCTGACGCGCGACACGGATGTCAGCGAGGAGATTGCTGAAGCGCT
GGGGGATTGCCTGGGCTCAGCCACGTCGCTGCCGCTACTCGCCATGGGCCGGGACATCCCCAACGGGAACATGCGGCTGA
CACGAGATGGGAAGCTGGACATCGACTGGCGCATGCATGGTTCGCGCGAGTACTTCGGCCGTGTGCGGAAATCCATGGAG
GACATCGCCGACGCGCTGGAGGCGAAGATGGTGCACAACCCCCTCAGTTACTTGAGCCGGGTCATCACCGTGCATCCGCT
GGGTGGTTGCCCCATGGGACAGACGCCAGCAGAAGGGGTGGTGAACGCCCATGGCGAGGCGTTCCACTACCCCGGCCTGT
ACGTGGCGGACGGCTCGGTGATGCCTGGCCCCACCGGCCCCAACCCGAGCCTCACCATCGCCGCGCTCGCGGACCGGTTC
TCAGACCACTTGATTGCGCACTGGCCACGAACCACGGCGCTCCGCAAACACCCCACCACGGAGGAACGCATATGA

Upstream 100 bases:

>100_bases
TCGGCAGGTTCTTCCTGGGGACGCTTTGGGACGTCTATGCGCCCTGGGCCCGGCAGGCGGGGGAAGCGCCCTCCGCCTCA
TCCATGGAGAGGAGCTTGTA

Downstream 100 bases:

>100_bases
CGATACGAGCTGCCGGCGGGGGAACCGCCATCGGCGCCGGGGGACGCCACGAACCACGCAAGCCGCATGGCAAACCGATG
GTGCGGTGGTTCCACCCGAG

Product: hypothetical protein

Products: cholest-4-en-3-one; H2O2

Alternate protein names: Glucose-Methanol-Choline Oxidoreductase; FAD Dependent Oxidoreductase; GMC Oxidoreductase; Oxidoreductase; Choline Dehydrogenase-Like Flavoprotein; Choline Dehydrogenase; Cholesterol Oxidase ChoD; Oxidase; Oxidoreductase Glucose-Methanol-Choline Family; FAD-Dependent Pyridine Nucleotide-Disulfide Oxidoreductase; Gmc Oxidoreductase Family Protein; Ferredoxin Domain Gmc Oxidoreductase; Cholesterol Oxidase ChoD; GMC Family Oxidoreductase; Cholesterol-O2 Oxidoreductase; Fad-Dependent Pyridine Nucleotide-Disulfide Oxidoreductase; GMC Oxidoreductase Family Protein; Cholesterol Oxidase Chod; GMC Oxidoreductase Family

Number of amino acids: Translated: 584; Mature: 583

Protein sequence:

>584_residues
MAFRPEHFDAIIVGSGFGGSVMAYRLAEAGLRVCVLERGKAYPPGTFPRSPYDMRNNFWDPSKGLHGMFNLWSFRGLGGV
VSSGLGGGSLIYANVMLRKDEKTFVHEHPQTGGYEYWPVTRDDLEEHYDAVERMMHVQRFPLAHPPYDATAKTLAMKLAA
ERLGRAADWQLPPLAITFANAGAAPALGEPIREAAPNLFGRMRTTCRLCGECDIGCNYGSKNTLDFTYLSAAHRAGADLR
TRAEVKEFWPADGGGYVVQYVDHAEAREGERREVASDQLQRVTLTADRLVLGAGTFGTTYLLLKNRAHFPRLSARLGTRF
CGNGDLLGFLLRSVDSSSGTRLPRVLDGGRGPVITSALHFRGKEEGGTGRGYYIEDAGYPEFINWLYEGSQQAPLLRRGM
RLAWRLVKGWIGLTRDTDVSEEIAEALGDCLGSATSLPLLAMGRDIPNGNMRLTRDGKLDIDWRMHGSREYFGRVRKSME
DIADALEAKMVHNPLSYLSRVITVHPLGGCPMGQTPAEGVVNAHGEAFHYPGLYVADGSVMPGPTGPNPSLTIAALADRF
SDHLIAHWPRTTALRKHPTTEERI

Sequences:

>Translated_584_residues
MAFRPEHFDAIIVGSGFGGSVMAYRLAEAGLRVCVLERGKAYPPGTFPRSPYDMRNNFWDPSKGLHGMFNLWSFRGLGGV
VSSGLGGGSLIYANVMLRKDEKTFVHEHPQTGGYEYWPVTRDDLEEHYDAVERMMHVQRFPLAHPPYDATAKTLAMKLAA
ERLGRAADWQLPPLAITFANAGAAPALGEPIREAAPNLFGRMRTTCRLCGECDIGCNYGSKNTLDFTYLSAAHRAGADLR
TRAEVKEFWPADGGGYVVQYVDHAEAREGERREVASDQLQRVTLTADRLVLGAGTFGTTYLLLKNRAHFPRLSARLGTRF
CGNGDLLGFLLRSVDSSSGTRLPRVLDGGRGPVITSALHFRGKEEGGTGRGYYIEDAGYPEFINWLYEGSQQAPLLRRGM
RLAWRLVKGWIGLTRDTDVSEEIAEALGDCLGSATSLPLLAMGRDIPNGNMRLTRDGKLDIDWRMHGSREYFGRVRKSME
DIADALEAKMVHNPLSYLSRVITVHPLGGCPMGQTPAEGVVNAHGEAFHYPGLYVADGSVMPGPTGPNPSLTIAALADRF
SDHLIAHWPRTTALRKHPTTEERI
>Mature_583_residues
AFRPEHFDAIIVGSGFGGSVMAYRLAEAGLRVCVLERGKAYPPGTFPRSPYDMRNNFWDPSKGLHGMFNLWSFRGLGGVV
SSGLGGGSLIYANVMLRKDEKTFVHEHPQTGGYEYWPVTRDDLEEHYDAVERMMHVQRFPLAHPPYDATAKTLAMKLAAE
RLGRAADWQLPPLAITFANAGAAPALGEPIREAAPNLFGRMRTTCRLCGECDIGCNYGSKNTLDFTYLSAAHRAGADLRT
RAEVKEFWPADGGGYVVQYVDHAEAREGERREVASDQLQRVTLTADRLVLGAGTFGTTYLLLKNRAHFPRLSARLGTRFC
GNGDLLGFLLRSVDSSSGTRLPRVLDGGRGPVITSALHFRGKEEGGTGRGYYIEDAGYPEFINWLYEGSQQAPLLRRGMR
LAWRLVKGWIGLTRDTDVSEEIAEALGDCLGSATSLPLLAMGRDIPNGNMRLTRDGKLDIDWRMHGSREYFGRVRKSMED
IADALEAKMVHNPLSYLSRVITVHPLGGCPMGQTPAEGVVNAHGEAFHYPGLYVADGSVMPGPTGPNPSLTIAALADRFS
DHLIAHWPRTTALRKHPTTEERI

Specific function: Unknown

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.1.3.6

Molecular weight: Translated: 64250; Mature: 64119

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFRPEHFDAIIVGSGFGGSVMAYRLAEAGLRVCVLERGKAYPPGTFPRSPYDMRNNFWD
CCCCCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHCCCCC
PSKGLHGMFNLWSFRGLGGVVSSGLGGGSLIYANVMLRKDEKTFVHEHPQTGGYEYWPVT
CCCCCHHHHHHHHHHCCCHHHHCCCCCCEEEEEEEEEECCCHHHHHCCCCCCCEEECCCC
RDDLEEHYDAVERMMHVQRFPLAHPPYDATAKTLAMKLAAERLGRAADWQLPPLAITFAN
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECC
AGAAPALGEPIREAAPNLFGRMRTTCRLCGECDIGCNYGSKNTLDFTYLSAAHRAGADLR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHCCCCHH
TRAEVKEFWPADGGGYVVQYVDHAEAREGERREVASDQLQRVTLTADRLVLGAGTFGTTY
HHHHHHHHCCCCCCCEEEEEECHHHHCCCHHHHHHHHHHHEEEEEECEEEEECCCCCCEE
LLLKNRAHFPRLSARLGTRFCGNGDLLGFLLRSVDSSSGTRLPRVLDGGRGPVITSALHF
EEEECCCCCCHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHCCCCCCEEEHHHHH
RGKEEGGTGRGYYIEDAGYPEFINWLYEGSQQAPLLRRGMRLAWRLVKGWIGLTRDTDVS
CCCCCCCCCCCEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHH
EEIAEALGDCLGSATSLPLLAMGRDIPNGNMRLTRDGKLDIDWRMHGSREYFGRVRKSME
HHHHHHHHHHHCCCCCCCHHHHCCCCCCCCEEEEECCCEEEEEEECCCHHHHHHHHHHHH
DIADALEAKMVHNPLSYLSRVITVHPLGGCPMGQTPAEGVVNAHGEAFHYPGLYVADGSV
HHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCHHCCCCCEEECCCEEEECCCC
MPGPTGPNPSLTIAALADRFSDHLIAHWPRTTALRKHPTTEERI
CCCCCCCCCCEEHHHHHHHHHCCCEEECCCHHHHCCCCCHHCCC
>Mature Secondary Structure 
AFRPEHFDAIIVGSGFGGSVMAYRLAEAGLRVCVLERGKAYPPGTFPRSPYDMRNNFWD
CCCCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHCCCCC
PSKGLHGMFNLWSFRGLGGVVSSGLGGGSLIYANVMLRKDEKTFVHEHPQTGGYEYWPVT
CCCCCHHHHHHHHHHCCCHHHHCCCCCCEEEEEEEEEECCCHHHHHCCCCCCCEEECCCC
RDDLEEHYDAVERMMHVQRFPLAHPPYDATAKTLAMKLAAERLGRAADWQLPPLAITFAN
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECC
AGAAPALGEPIREAAPNLFGRMRTTCRLCGECDIGCNYGSKNTLDFTYLSAAHRAGADLR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHCCCCHH
TRAEVKEFWPADGGGYVVQYVDHAEAREGERREVASDQLQRVTLTADRLVLGAGTFGTTY
HHHHHHHHCCCCCCCEEEEEECHHHHCCCHHHHHHHHHHHEEEEEECEEEEECCCCCCEE
LLLKNRAHFPRLSARLGTRFCGNGDLLGFLLRSVDSSSGTRLPRVLDGGRGPVITSALHF
EEEECCCCCCHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHCCCCCCEEEHHHHH
RGKEEGGTGRGYYIEDAGYPEFINWLYEGSQQAPLLRRGMRLAWRLVKGWIGLTRDTDVS
CCCCCCCCCCCEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHH
EEIAEALGDCLGSATSLPLLAMGRDIPNGNMRLTRDGKLDIDWRMHGSREYFGRVRKSME
HHHHHHHHHHHCCCCCCCHHHHCCCCCCCCEEEEECCCEEEEEEECCCHHHHHHHHHHHH
DIADALEAKMVHNPLSYLSRVITVHPLGGCPMGQTPAEGVVNAHGEAFHYPGLYVADGSV
HHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCHHCCCCCEEECCCEEEECCCC
MPGPTGPNPSLTIAALADRFSDHLIAHWPRTTALRKHPTTEERI
CCCCCCCCCCEEHHHHHHHHHCCCEEECCCHHHHCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: cholesterol; O2

Specific reaction: cholesterol + O2 = cholest-4-en-3-one + H2O2

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA