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The map label for this gene is pcbC [H]

Identifier: 108759555

GI number: 108759555

Start: 99616

End: 100686

Strand: Direct

Name: pcbC [H]

Synonym: MXAN_0088

Alternate gene names: 108759555

Gene position: 99616-100686 (Clockwise)

Preceding gene: 108762425

Following gene: 108759330

Centisome position: 1.09

GC content: 70.31

Gene sequence:

>1071_bases
ATGACAGGTCCGGATTCCGCACGGGGCGGCTTGCCCGTCATCGACATGGCGTCACTGTTCGATGCATCCCGCGTCACCGA
GCGTGCGCGCGTCGCGCGTGAAATCGAGCAGGCCTGTCGCGACAGCGGCTTCTTCTACGTGACGGGCCACGGCGTGTCCG
GCGAGGTGCTCGCGCGGCTGGAGCGGGAGAGCCACCGCTTCTTTGCGCTGCCCCGGGTGGCGAAGGAGGCCATCGCCATG
TCGATGGGCGGTGTCGCGTGGCGAGGCTGGTTTCCACTCGGGGGGGAGCTGACCTCGGGGCGCCCGGACCGGAAGGAGGG
GTTGTATCTGGGCACGGAGCTCGGAAGCGAGCATCCGCGCGTAAAGGCCGGCTGGCCGTTGCACGGCGCCAACCTGTGGC
CCGCGGAGGTGCCGGAGCTGCGCGCGGCGGTGCTCGACTACGTGGCGGCCTGCACGCGCGCCGCGCATGCGCTGATGGAG
GGCATGGCGCTGAGCCTGGGCCTGGACGCGGACTACTTCCGGCGGCACTACACGGCGGACCCGACGGTGCTCTTCCGCAT
CTTCCATTACCCCGCGGAGCCCCAGCACGAGGAGGTGAGCTGGGGCGTGGGCGAGCACACCGACTACGGGCTGCTCACGC
TGCTGGCCCAGGACGACAACGGCGGGTTGCAGGTGAAGACGCCGCGCGGCTGGGTGGAGGTACCGCCGCTGCCCGGGACG
CTGGTGTGCAACATCGGCGACATGCTCGACCGGATGACAGGCGGGTGGTACCGCTCCACGCCGCACCGGGTGAAGAACGT
GAGCGGCAAGGACAGGCTGTCCTTCCCACTCTTCTTCGACCCGGACTTCGCCGCCGAGGTCCACCCCCTGCCACGCGGCG
CGGGCGCTGACGTAGATGATGACCGCGCCCGCCGCTGGGATGGCGCCAGCGTCCACGCCTTCCAGGGCACGTACGGCGAC
TACCTGCTGGGCAAGGTGTCCAAGGTGTTTCCGGAGCTGGTGCGGCGGGTGTGGGAGCGCGCGCCCACGGCACTGCCGGA
GGAGACACCCCGAGGACCGTTACCGCGTTGA

Upstream 100 bases:

>100_bases
GCGGTGTGGGGAGCTTCCGGGGAGGAATGCGTTGTCATGGAGGCGGGCGGACTCTCGCGCCGCGCCCTGCTGGGGTCCAG
ACCTGTGTAGGCTCCCGGGA

Downstream 100 bases:

>100_bases
CGGAGCCCGGGGCGCATGCTTGAGAGCGCTGCGCCGGATGACGCGCTTCGGCGCGCCCAAACCGCTCACCGACCAGGAGA
CATCACGATGATGACCGTCA

Product: 2OG-Fe(II) oxygenase family oxidoreductase

Products: NA

Alternate protein names: IPNS [H]

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MTGPDSARGGLPVIDMASLFDASRVTERARVAREIEQACRDSGFFYVTGHGVSGEVLARLERESHRFFALPRVAKEAIAM
SMGGVAWRGWFPLGGELTSGRPDRKEGLYLGTELGSEHPRVKAGWPLHGANLWPAEVPELRAAVLDYVAACTRAAHALME
GMALSLGLDADYFRRHYTADPTVLFRIFHYPAEPQHEEVSWGVGEHTDYGLLTLLAQDDNGGLQVKTPRGWVEVPPLPGT
LVCNIGDMLDRMTGGWYRSTPHRVKNVSGKDRLSFPLFFDPDFAAEVHPLPRGAGADVDDDRARRWDGASVHAFQGTYGD
YLLGKVSKVFPELVRRVWERAPTALPEETPRGPLPR

Sequences:

>Translated_356_residues
MTGPDSARGGLPVIDMASLFDASRVTERARVAREIEQACRDSGFFYVTGHGVSGEVLARLERESHRFFALPRVAKEAIAM
SMGGVAWRGWFPLGGELTSGRPDRKEGLYLGTELGSEHPRVKAGWPLHGANLWPAEVPELRAAVLDYVAACTRAAHALME
GMALSLGLDADYFRRHYTADPTVLFRIFHYPAEPQHEEVSWGVGEHTDYGLLTLLAQDDNGGLQVKTPRGWVEVPPLPGT
LVCNIGDMLDRMTGGWYRSTPHRVKNVSGKDRLSFPLFFDPDFAAEVHPLPRGAGADVDDDRARRWDGASVHAFQGTYGD
YLLGKVSKVFPELVRRVWERAPTALPEETPRGPLPR
>Mature_355_residues
TGPDSARGGLPVIDMASLFDASRVTERARVAREIEQACRDSGFFYVTGHGVSGEVLARLERESHRFFALPRVAKEAIAMS
MGGVAWRGWFPLGGELTSGRPDRKEGLYLGTELGSEHPRVKAGWPLHGANLWPAEVPELRAAVLDYVAACTRAAHALMEG
MALSLGLDADYFRRHYTADPTVLFRIFHYPAEPQHEEVSWGVGEHTDYGLLTLLAQDDNGGLQVKTPRGWVEVPPLPGTL
VCNIGDMLDRMTGGWYRSTPHRVKNVSGKDRLSFPLFFDPDFAAEVHPLPRGAGADVDDDRARRWDGASVHAFQGTYGDY
LLGKVSKVFPELVRRVWERAPTALPEETPRGPLPR

Specific function: Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin [H]

COG id: COG3491

COG function: function code R; Isopenicillin N synthase and related dioxygenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe2OG dioxygenase domain [H]

Homologues:

Organism=Drosophila melanogaster, GI28572124, Length=304, Percent_Identity=25, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI85816264, Length=302, Percent_Identity=24.5033112582781, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002057
- InterPro:   IPR002283
- InterPro:   IPR005123 [H]

Pfam domain/function: PF03171 2OG-FeII_Oxy [H]

EC number: =1.21.3.1 [H]

Molecular weight: Translated: 39324; Mature: 39193

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGPDSARGGLPVIDMASLFDASRVTERARVAREIEQACRDSGFFYVTGHGVSGEVLARL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHH
ERESHRFFALPRVAKEAIAMSMGGVAWRGWFPLGGELTSGRPDRKEGLYLGTELGSEHPR
HHHCCCEEECHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCEEEECCCCCCCCC
VKAGWPLHGANLWPAEVPELRAAVLDYVAACTRAAHALMEGMALSLGLDADYFRRHYTAD
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHCCCC
PTVLFRIFHYPAEPQHEEVSWGVGEHTDYGLLTLLAQDDNGGLQVKTPRGWVEVPPLPGT
HHHEEHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEECCCCCEECCCCCCE
LVCNIGDMLDRMTGGWYRSTPHRVKNVSGKDRLSFPLFFDPDFAAEVHPLPRGAGADVDD
EEECHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCC
DRARRWDGASVHAFQGTYGDYLLGKVSKVFPELVRRVWERAPTALPEETPRGPLPR
HHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TGPDSARGGLPVIDMASLFDASRVTERARVAREIEQACRDSGFFYVTGHGVSGEVLARL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHH
ERESHRFFALPRVAKEAIAMSMGGVAWRGWFPLGGELTSGRPDRKEGLYLGTELGSEHPR
HHHCCCEEECHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCEEEECCCCCCCCC
VKAGWPLHGANLWPAEVPELRAAVLDYVAACTRAAHALMEGMALSLGLDADYFRRHYTAD
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHCCCC
PTVLFRIFHYPAEPQHEEVSWGVGEHTDYGLLTLLAQDDNGGLQVKTPRGWVEVPPLPGT
HHHEEHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEECCCCCEECCCCCCE
LVCNIGDMLDRMTGGWYRSTPHRVKNVSGKDRLSFPLFFDPDFAAEVHPLPRGAGADVDD
EEECHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCC
DRARRWDGASVHAFQGTYGDYLLGKVSKVFPELVRRVWERAPTALPEETPRGPLPR
HHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1956290 [H]