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The map label for this gene is yfmJ [H]

Identifier: 108759447

GI number: 108759447

Start: 2488538

End: 2489563

Strand: Direct

Name: yfmJ [H]

Synonym: MXAN_2152

Alternate gene names: 108759447

Gene position: 2488538-2489563 (Clockwise)

Preceding gene: 108764030

Following gene: 108757487

Centisome position: 27.23

GC content: 68.91

Gene sequence:

>1026_bases
ATGAGCACGACGTCCAATCGTCAGTGGGTGCTGAAGACCCGTCCCCGGGAAGCGGTGTCCGAAGACTGCTTCGAGTGGCG
CGAGGGGCCCGTGCCGACGCCAGGCCCGGGTGAGGCGCTGGTCCGCGTCACCTGGCTCGCCATCGAGCCCACCCAGCGCA
CCTGGCTCAATGCAAATGCGACGTACATCCAGCCCGTCGCGCTCGGTGAGGTGATGCGGGGCGCAGGCGTGGGCCTGGTC
ATCGCGTCCCGAACCGAGCGGCTGGCGGTGGGTGACTGGGTGGCCGGGCTCACCGGTTGGCAGGACTATGTACTGACCGG
CGACGCGGGGCTCTTCGGCCTCAACAAGGTACCGGACGGCGTCGCTCCGAAGGCGATGCTGAACCTCTATGGCGCGAGCG
GGCTGACGGCGTACTTCGGCATCACCGAGGTGGGCCGCGTTGCGCCGGGAGAGACAGTTCTGGTGTCCGCCGCCGCGGGC
AGCGTGGGCTCCATCGCGGGGCAGGTGGCCCGGCTCCGGGGCTGCCGTGTCATTGGCATCGCGGGAGGGCCGCACAAGGC
CGAATGGGTCACCCGCACCGCGCGCTTCGATGCCTGCATCGACTACAAGTCTGAAGACATCCGGGCGCGGCTTCGCGCCC
TGGCGCCTCAAGGCGTGGACGTCGTCTTCGACAACGTGGGGGGCCACGTCCTGGAAGCCGCGCTGGACCACCTCGCCCGA
GGCGCGCGGGTGGTGCTCTCCGGCAGCGTGGCCTCGGGATACAAGGACGGTGACTACGGCACCGCGCCGCGCAACTACAT
GCAGCTCGGCTTCAAGCGAGCGCGGATGGAGGGCTTCATCTTCCTCGACTACGTCTCGCGCTTTCCTGAGGCTTTTCGCG
AGCTGGCGGCTTGGGACGCCCAGGGCGCGCTCCATTGCGCGGAGTCCATCGCGGAAGGCTTGGAGCAGGCCCCCTCTGCC
CTGCGAGGACTCTTCGAAGGCCGCAACGTGGGCAAGCAGCTCGTGCGCGTCACCTCAATCCCCTGA

Upstream 100 bases:

>100_bases
GGCACCGCGCCCGGTTCAATCAGTGGACCCGAAGCTGGCCGGACGACCTCAGGAATCACGCGCGCCGGCTGGCCGCGCCC
GCGTTCGGAAAGGTGACGCC

Downstream 100 bases:

>100_bases
TCCCCAACGGCATCTGGAAGAACGTCACACGTCGCCGAACGGCGCCACCTGCTTGTTCAGCCAGACGGCATCCCGCTTCC
CGCCCCCCTCGGTGAGCTGC

Product: zinc-binding dehydrogenase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MSTTSNRQWVLKTRPREAVSEDCFEWREGPVPTPGPGEALVRVTWLAIEPTQRTWLNANATYIQPVALGEVMRGAGVGLV
IASRTERLAVGDWVAGLTGWQDYVLTGDAGLFGLNKVPDGVAPKAMLNLYGASGLTAYFGITEVGRVAPGETVLVSAAAG
SVGSIAGQVARLRGCRVIGIAGGPHKAEWVTRTARFDACIDYKSEDIRARLRALAPQGVDVVFDNVGGHVLEAALDHLAR
GARVVLSGSVASGYKDGDYGTAPRNYMQLGFKRARMEGFIFLDYVSRFPEAFRELAAWDAQGALHCAESIAEGLEQAPSA
LRGLFEGRNVGKQLVRVTSIP

Sequences:

>Translated_341_residues
MSTTSNRQWVLKTRPREAVSEDCFEWREGPVPTPGPGEALVRVTWLAIEPTQRTWLNANATYIQPVALGEVMRGAGVGLV
IASRTERLAVGDWVAGLTGWQDYVLTGDAGLFGLNKVPDGVAPKAMLNLYGASGLTAYFGITEVGRVAPGETVLVSAAAG
SVGSIAGQVARLRGCRVIGIAGGPHKAEWVTRTARFDACIDYKSEDIRARLRALAPQGVDVVFDNVGGHVLEAALDHLAR
GARVVLSGSVASGYKDGDYGTAPRNYMQLGFKRARMEGFIFLDYVSRFPEAFRELAAWDAQGALHCAESIAEGLEQAPSA
LRGLFEGRNVGKQLVRVTSIP
>Mature_340_residues
STTSNRQWVLKTRPREAVSEDCFEWREGPVPTPGPGEALVRVTWLAIEPTQRTWLNANATYIQPVALGEVMRGAGVGLVI
ASRTERLAVGDWVAGLTGWQDYVLTGDAGLFGLNKVPDGVAPKAMLNLYGASGLTAYFGITEVGRVAPGETVLVSAAAGS
VGSIAGQVARLRGCRVIGIAGGPHKAEWVTRTARFDACIDYKSEDIRARLRALAPQGVDVVFDNVGGHVLEAALDHLARG
ARVVLSGSVASGYKDGDYGTAPRNYMQLGFKRARMEGFIFLDYVSRFPEAFRELAAWDAQGALHCAESIAEGLEQAPSAL
RGLFEGRNVGKQLVRVTSIP

Specific function: Putative quinone oxidoreductase that may contribute to the degradation of aromatic compounds (Potential) [H]

COG id: COG2130

COG function: function code R; Putative NADP-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADP-dependent oxidoreductase L4BD family [H]

Homologues:

Organism=Homo sapiens, GI226246682, Length=343, Percent_Identity=32.3615160349854, Blast_Score=171, Evalue=8e-43,
Organism=Homo sapiens, GI226246680, Length=343, Percent_Identity=32.3615160349854, Blast_Score=171, Evalue=8e-43,
Organism=Homo sapiens, GI22748929, Length=343, Percent_Identity=32.3615160349854, Blast_Score=171, Evalue=8e-43,
Organism=Homo sapiens, GI226059159, Length=334, Percent_Identity=29.6407185628743, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI226059133, Length=334, Percent_Identity=29.6407185628743, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI226056130, Length=296, Percent_Identity=28.7162162162162, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI28557745, Length=344, Percent_Identity=30.8139534883721, Blast_Score=119, Evalue=4e-27,
Organism=Escherichia coli, GI226510941, Length=337, Percent_Identity=37.9821958456973, Blast_Score=233, Evalue=9e-63,
Organism=Escherichia coli, GI1790485, Length=172, Percent_Identity=30.8139534883721, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI133901712, Length=356, Percent_Identity=34.8314606741573, Blast_Score=175, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI133901710, Length=360, Percent_Identity=34.7222222222222, Blast_Score=175, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6323504, Length=366, Percent_Identity=28.6885245901639, Blast_Score=140, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6319520, Length=244, Percent_Identity=28.2786885245902, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00107 ADH_zinc_N [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36471; Mature: 36340

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTSNRQWVLKTRPREAVSEDCFEWREGPVPTPGPGEALVRVTWLAIEPTQRTWLNANA
CCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEECCCCHHEECCCC
TYIQPVALGEVMRGAGVGLVIASRTERLAVGDWVAGLTGWQDYVLTGDAGLFGLNKVPDG
CEECHHHHHHHHHCCCCEEEEECCCCEEEHHHHHHHCCCCCCEEEECCCCCCCCCCCCCC
VAPKAMLNLYGASGLTAYFGITEVGRVAPGETVLVSAAAGSVGSIAGQVARLRGCRVIGI
CCHHHHHHHHCCCCCHHHHCHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEE
AGGPHKAEWVTRTARFDACIDYKSEDIRARLRALAPQGVDVVFDNVGGHVLEAALDHLAR
CCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHC
GARVVLSGSVASGYKDGDYGTAPRNYMQLGFKRARMEGFIFLDYVSRFPEAFRELAAWDA
CCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHCCC
QGALHCAESIAEGLEQAPSALRGLFEGRNVGKQLVRVTSIP
CCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCC
>Mature Secondary Structure 
STTSNRQWVLKTRPREAVSEDCFEWREGPVPTPGPGEALVRVTWLAIEPTQRTWLNANA
CCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEECCCCHHEECCCC
TYIQPVALGEVMRGAGVGLVIASRTERLAVGDWVAGLTGWQDYVLTGDAGLFGLNKVPDG
CEECHHHHHHHHHCCCCEEEEECCCCEEEHHHHHHHCCCCCCEEEECCCCCCCCCCCCCC
VAPKAMLNLYGASGLTAYFGITEVGRVAPGETVLVSAAAGSVGSIAGQVARLRGCRVIGI
CCHHHHHHHHCCCCCHHHHCHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEE
AGGPHKAEWVTRTARFDACIDYKSEDIRARLRALAPQGVDVVFDNVGGHVLEAALDHLAR
CCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHC
GARVVLSGSVASGYKDGDYGTAPRNYMQLGFKRARMEGFIFLDYVSRFPEAFRELAAWDA
CCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHCCC
QGALHCAESIAEGLEQAPSALRGLFEGRNVGKQLVRVTSIP
CCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377 [H]