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The map label for this gene is grsB [H]

Identifier: 108759320

GI number: 108759320

Start: 5012499

End: 5025896

Strand: Direct

Name: grsB [H]

Synonym: MXAN_4079

Alternate gene names: 108759320

Gene position: 5012499-5025896 (Clockwise)

Preceding gene: 108760392

Following gene: 108761559

Centisome position: 54.84

GC content: 69.73

Gene sequence:

>13398_bases
ATGACGTCAGAAGAGTCGATCGAGGACATCTACGAGCTCGCCCCCATGCAGCACGGCATGCTCTTCCACGCGCTGATGGA
GCCCGGCGCGGGCATGTACGTGGAGCAACTGAGCTGCGAGGTCCGGGGGGACCTGCCCATCAACCGTTGGAAGGAGGCCT
GGCAGCACGTCCTCGCCCGGCACCCCATCCTGCGCTCCGGCTTCCTCTGGGAAGGCCTGGAGAAGCCGCTCCAGGTCGTC
GCGGTGGAGGCCGAAGTCCCCTGGCGCATCGAGGACATCCGACATGTGCCGGAGGACGCGCAGCAGCGGTGGATTGACGA
CTTCCTGCGCGAGGACCGGCTCCAGGGCTTCGACCTGGGCACGCCGCCCCTGATTCGTTGCGCGCTGATCCGGCTCGATG
ATGCGCGCCACCTGTTCGTGTGGACCTACCACCACCTGCTGCTGGACGGGTGGTGCTTCTCCATCGTCCTCCGCGAGGTG
CTCGGTGCCTTCGAGGAGGGCGTCGCAGCGCTGCCGCCAGCCGCACGCCCCTACCGCGACTACATCGCCTGGCTCCAGGA
GCAGGACCCCTCCCGCGCGGAGTCCTTCTGGCGCGAGCGGCTCCAGGGCTTCAAGCAACCCACGCCACTGCCCTTCACCG
AGCGACAGGACACCAGCGAACCGGCCGGCGATACGCAGCCGGAAGTCACAAAGCGGCTGTCGCCAGAGCTGACCGCGCGG
CTCACGGGCTTCGCGAAGGCGCACCGGCTGACGCTCAACACGCTGGTCCAGGGTGCGTGGGCGCTGGTCCTGGCGAGAGC
GACAGGCACGGACGACGTCATCTTCGGTGTGACGGTCTCCGGCCGTCCCGCCGACCTTGCCGGTTCCGAGTCCATTGTCG
GGCTCTTCATCAACACCCTGCCCCTGAGAGCGCGGCTGGACGGCACGGCGCCGGTCGCCACGTTCCTGTCGGGGCTTCAG
ACTGAGCAAGGCGCGGTCGAGCCGTACAGCTACGCCTCGCTGGCGGACATCCAGCACTGGTCGGACGCGCCGAAGGACCG
GCCGCTCTTCGAGAGCATCCTGGTGTTCGAGAACTATCCGCTCGACGCCTCGACGCTCCTGCCTCGCAGTGGCCTCACCA
TCAGCTCGGTCAACACGCACGACCGCATCAGCTACCCACTGGCGCTGGTCGCTATCCCGGGCGAGTCGCTGGAGTTGCGC
GTCATGTATGCGGCGGACGCGTTCTCCCGCCCGATGGCGGAGCGCATCGCGCGGTTGCTGGAAGCCGCGCTCGAGTCGCT
GCCGGGCGCGAAGACGGTCGGCGATATCGACCTGATGGACGAGGCCGCCCGGCGCGTGCTGGCGGAGTGGGGCCAGCATC
CCCGTGCCTACGATGTCACCCGCCCTGTGACAGCCCTGCTGGACGGGGCCGCACCCGACGCGACCGCCGTGGTGGGCCCC
GACGGCCAATCCATCAGCTACCGCGAACTCGACCGCCGCGCCGAGCGCGTGGCGCGGCACCTCCGACAGTTGGGCGCCGG
TCGGGAGCGCATCGTCGGCGTGTGCATTGGCAGGTCCGTGGAGATGGTGGTGGCGCTCCTGGGCGTGCTCAAGGCGGGAG
CGGCCTACCTGCCCCTGGACCCCAACTATCCCGCTGAGCGGCTGGCCTACATCGTGGGCGATGCGGCGCCGGTCGCCATC
CTCAACACGGGTGCGGACCCCATCGCGGACACGCGCGTTCCCCGGCTCGACGTCTCCCGAGTCCTGAACGAGACGGCCAC
GCCCGACGTCCCCGCGAAGGAGCCGGTGCAGCTGGATGACCTGGCCTACGTCATCTACACCTCGGGTTCGACCGGCGCGC
CCAAGGGCGTCCTGGTCACACACCGGAACCTGATGAACCTGGTGTCCTGGCACACGGAGGCTTTCGGCCTCACGGCGAAG
GACCGGACGACCCAGCTCGCCAGCACCGCGTTCGACGCCTCCGTCTGGGAAATCTGGCCGACGCTCGCTGCGGGCGCCAC
GCTGCACCTGGTCCCACCCGAGCTGTCCAGTGCGCCCTCCGACCTGGCGAATTGGCTGGTGGCGCAGCAGATCTCCATCA
GCTTCCTGCCGACGGTGGTCGCAGAGGCCGTGCTGGCCTTGCAGTGGCCTTCGCCGTGCGCGCTGCGCTTCGTGCTCACG
GGCGGCGACCGGCTCCACGCCACACCGCCCGCGGGACTTCCGTTCCAGCTCGTCAACAACTATGGCCCCACCGAGACGAC
GGTGGTGGCGACATCCGGAACCGTTGCGCCGGATGGCAAACAAGGGCTGCCCTCCATCGGCCGGCCGGTCGCCAATGCCC
GCATCTACATCCTCGACCGCCAGCGGCGTCCCGTCCTTCCGGGTGTCATCGGAGAGCTGTACATCGGCGGCGTGGGCGTC
ACCCGGGGCTACCTGAACCGGCCGGACCTGAACGTGGAGCGCTTCGTTCCCGACCCGTTCGCGGGCGTGCCTGAAGCGCG
CATGTACGCGAGCGGTGACTTCGCCCGGTTCCTCCCAGATGGAACCATCGCGTTCCACGGCCGCGCGGACCGTCAGGTCC
AGATTCGCGGCGTGCGGGTGGAGCTTGGCGAAATCGAGGCCGCGCTGGCGGCCCACCCCGACGTCACCGCTGCTGCCGTG
GTGAGCGAGGCGCAGCGGCAGAACGGCGACGTTCGGCTGATTGCGTTTGCTGTCAGCGACGTGGTGCCTCAGCCCGACGC
GGCCGTGCTCACGCAGTTTCTGGCGACGAAGCTCCCCACGGCCATCCTTCCCAGCCGGGTCATCGTCATCGACCGGCTTC
CGCTGACGCCCAACGGGAAGGTCGACACCGCGGCGCTCGAAGCACGTGCCCTGGAGGCCCAGCCCCAGGTGGCTTCGGCC
GCGCCCCGGACGCCCCATGAGGAGATTCTCGCCGGCATCTGGAGCGCGGTGCTCGGCCAGGAGCGCGTGGGCATCCACGA
TGACTTCTTCGACCTCGGTGGGCATTCACTGAAGGCGACGCAGGTCATCGCGCGCACCCGCGAGGCCTTCGGCGTCGACA
TTCCCGTCCGAGCCATCTTCGAGCGCCGGACCATCGCGCAGCTCGCGGAGACGCTCTCCGGACAGGGCACGGCGGTCGAG
CCCATCCCGCACGTGGAGCTGACGGGAGACACGCCCGTCGCTCCGGGCCAGGAGAGCCTGTGGTTCATCGACGCGCTCGG
AGGAGACAGCGCGGCGTACAACGTCCCGTTGGTGCTCAGGCTCCAGGGGACGCTCGATGGCAGCGCGCTCGCAAGGACGC
TCCAGCTCCTGGTTGAACGCCATGAGGCGCTCCGGAGCACCTTCCACGACCGTGGAGGCACGCCCGTCCTGCGAGTCCAG
GCACCTGCCGCCTCCGTGCTCGTGAGCGAGGACGTCTCCCCTGCCCTCCTCGACGCACGCATCGCCGAGGAGGTCGCCGC
GCCGTTCTCGCTGACGGACGGCCCGCTCTTCCGCGCGCGGCACTTCCGGCTCGCACCCGACAACCACGTCCTGGTCCTCA
ACCAGCACCACATCATCGCGGACGCCTGGTCCGTCGGGGTCCTGCTGCGCGAGTTCTGCATCGTGTACGCCTCGCTGGTG
AGCGGCACGGAGCCGGCCCTGCCCGCGTTGCCCATTCGCTACGCGGACTGGGCCGCATGGCAGCGGCAGCGGCTGGAATC
AGGACGCCTGGACGAGAGCGTTGCCTTCTGGCGTGAAGCCTTGAAGGACGCCCCGCCTGTCCTTCCGCTCCCCACCGACC
ATCCGCGACCGGAACGGCAGCGGTTCCATGGGAAGACTCATGGCTTCGTGCTGGACGCGCCGCTGGGCCAGCGGCTCGAA
GCGCTCTCCCGGAGCTCGGGCGCCTCGCTGTTCATGACCCTGCTTGGCGCCTTCGCCGCGTACCTCGGGCGCATCAGTGG
CCAGGAGGACGTGGTGATTGGCTCGCCTGTCGCCAATCGCGACCGGCACGAAACGGAGGGAGTGGTCGGGTACTTCCTCA
ACACGCTCGCGCTCCGCGTCGACCTGTCTGGAGACCCGACGTTCTCCGAGCTGTTGCTGCGCGTCCGCAAGACGGCGCTC
GATGCCTACGCGCATCAGGACGTGCCCTTCGAGAAGCTGGTGGCCGCACTCGAGCTACCGCGTGGACTTGCGCACAACCC
GCTGTTCCAGGTGATGTTCGTCCTCCAGGGGCAGAGCGGTGGCGAGCTCCAGCTCCCCGATGTTCGCGCCGAGATTCAAG
CGCCGGCGAGCTCGACGTCGAAGTTCGACCTCACCTTCTTCGTAGAGCCGCGTGAGGGCGCGCTCGCCTGCAGCATCGAG
TACGACACGGACCTCTTCGACGCGGACCGGATTGACCGGATGGCCGCGCACCTCGGCCGGCTGCTCCAGGCCATCGCCGA
GGAGCCCGAGCTCCACACCTCAGAGCTCCCGCTCTTGTCCAACGAGGAGCGGCGTCTGTACGCCGACCTCAACCGCACCG
AGCGCAGGTACACCGGCCGCACCCTCCCCGAGCTGTTCGAGCGTCAGGCCCAGAGGACGCCTGACGTGGTCGCGCTGGAG
CACCAGGGCGAGACGCGGACCTACCGCCAGCTCCATGAGGCCGCGGAAGCCCTGGCCGACCGGCTGGGCGCATTGGGCGT
GGGCCCAGGGGTCCGGGTTTCCATCTGTCTGGACCGCTCCATCCATGCGCAGGTCGCCCTCCTCGCGGTCCTCAAGGCCG
GGGGCGCATATGTGCCGCTCGATCCGACGTACCCGCCTGAGCGCCTTCGCTACATGCTGGAGGACGCCAGGCCGCGCGTC
CTGCTCACGGAGAAGAAGTACAGCGAGCTGCTCCCGTCTCAGGGCCTGACGCAGGTCCTGCTGGATGACACGGAGGCACC
TGCCACGAAGACACCGCGGCCCCGGGTGGAGCCGCATCATCTGGCCTACGTTCTCTACACGTCGGGCTCGACGGGCAAGC
CCAAGGGCGTGGCCATGCCGCACCGGGCACTGGTCAACCTCATCGAGTGGCAGACCGAACACGCCAGCCCCCTGCGCACG
CTCCAGTTCGCGCCGCTCAACTTCGATGTGTCGTTCCAGGAGACCTTCTCCACCTGGTGCTCGGGTGGCACGTTGGTCCT
CATCGATGAAGGCACCCGACGCGACCCAGACGCGTTGGCCGACTTCCTCGATGTGGCGCGCGTCCAACGCCTCTTCCTGC
CGGCCGTGGCGCTCCACCATCTGGCACAGGCCGCGCTGCGCACCGAGCATCGCGTTCCAGGGCTCACGGAAGTCATCACC
GCGGGAGACCAACTCCGCATCACCGACCCCATCCGCCGCTGGTTCCAGGAAGGTGGCAAGCGCCTTCACAACCACTACGG
CCCCACCGAATCGCATGTGGTGACGGCGCTCGAGTTGGAGGGCGACCCGCGGCATTGGCCTGGGCTGCCGTCCATCGGGC
GGCCCATCGCCAACGCGGCGGTCCACCTGCTCGACGCGAACCAGCGCCCCGTTCCGGTGGGAGTGCCCGGAGAGCTCTAT
CTGGCGGGCACGTGCCTCGCCGACGGCTACCTGTCACGGCCGGACCTCACCGCCGAGCGCTTCGTCGAGCTGCCCCTGTC
TCCCCCCGTGCGGGCGTACCGGACCGGGGACCTTGGCCGGTTGACGGTGGACGGGAGCATCGAGTTCCTCGGCCGCGCGG
ACGACCAGGTCAAGATTCGCGGCTTCCGTGTGGAGCCCGGCGAGATTGAGCGCGCCCTGTGTGCGCACCCCGATGTCCGC
GATGCGGCGGTCATCGTCGACGGTGATGCCACGCGCGAGAAGCGGCTGGTGGCCTACGTCGTCCCGGAGACGGTGCGGTT
GGCCGAGCTGCCCGACTTCCTCGCTAGGGACCTGCCCGAGTACATGGTTCCCGCGCTGTTCGTGCCGATGCCCGAGCTGC
CCCGGACGCCCAGTGGCAAGGTCGCGCGCCGTGCGCTCCCCGCCCCCGTCGCGCCCGTGCAGGCCGAGAGCCCATCCGAG
CCGCCTCGCACGCCTACGGAGGCGACCGTGGCACGGGCCTTTGAACAGGTCCTGGGACGCGGCGTTGTCGGGCGGGAGCA
GGACTTCTTCCAACTGGGCGGGCACTCGCTGCTCGCGATGCAGGTCGTCTCGCGGATTCGCGGCGACGTGGACGCTGCGT
TCCGCGTCTCCGACCTCTTCGAGAATCCGACCATCGCCTCCTTGAGCCGGGTGCTCGATGCGCGCCGGGGAAGCCAGACG
CTGACGCTTGCCCGGATTGAACCGGCGCCCGAGGGCGCCGCCATTCCGCTGTCATTCTCCCAGGAGCGGCTCTGGTTCCT
GGATCAGCTCTACCCCGGCACCACGGCCTACAACCTGCCCATGGCGCTGCGGCTGACGGGCACATTGGACGTCAGCGCCT
TCCAGGAAAGCCTGTCCGACATCGTCCGGCGGCACCCCGTGCTCGGGATGCGCTTCGTCGAGCGAGATGGCCGCGTGTGG
CAAGAGCCGCGGGCGAACCAGGACGTTCCGTTCGAGCAGGTCACCCTGGGAGAGACGTCCCCCGAGGCGCTTCGCCTGCT
CATCGCGGAGGAGGCCGCGCGACCGTTCGACCTGACAAACGGCCCGCTGTTCCGCGCGAAGCTGTTCTGCCTCGACGAGG
CGGCACACGTCGTCGTCGCGACGATGCATCACACCGTCGGTGACGGGTGGTCCATCAGCGTGCTCGTACGCGAGCTCTCC
CAGCTCTATGCCGGACGTGTCTCCGGCCAGCCGGTGACGCTGCCCGAGCTCCCCGTCGACTACCGGGACTTCGCGTACCA
GCAGCGGCGGCACCTCCAGGGCGAGGTGCTGGAGCAGCGGCTCGACCACTGGCGGAAGACGCTTCATGGCGCGCCGTCGG
CCCTGGACCTGCCCATGGACCGGCCTCGTCCTCCCCGGACGAGCATGCGCGGTGCCACCGAGCGCATCGCCCTGGGCAAG
GCGCTGAGCGAGGCCATCGAAGCCCTGAGCCTGCGCACGGGTGGAACCAGCTTCATGGTCCTCATGGGCGGATTCGCGGC
CTACCTGGCGCGCATCACCGGGCAGGATGACATCGTCATCGGTACGCCCGTGGCCAACCGCGACCGCGCGGAGCTCGAGT
CCCTGATTGGCTTCTTCGTCGGGACCCTGCCACTGCGCATCGACCTGTCCGCCAATCCGACCTTCGAGGAACTCGTCGCG
CGCGTCCGTGCCTCCGCGCTGGACGCCTACGCTTACCAGGACGTTCCCCTGGAGAAGATTGTCGAGGCGCTCGGGGTCGA
GCGGAACCTGAGCCACGCCCCGCTGTTCCAGGTGATGTTGATGCTGCAGAACACCCCGGAGGGCCACCTGAGCCTTCCGG
GGCTGGCGCTGGAGCCCATCGACCTGGAGATCGAGAGCGCGAAGTTCGACCTCACCTTGAGCTTCGAGCCCACGCGTGAA
GGGCTGGCCGGCGTCATCGAGTACAGCACGGACCTCTTCGACGCGGACCGCATCGAGCGGATGGTCGCCCACCTCCAGGT
GCTCTTCGCCGACGCGGTGGCGCATCCAGAGAAGCGGCTGTCAGAGCTCGCGCTCCTCCCCGAGCAGGAGCGCGGCGTCG
TCGCCGCGTTCACCCAGGGGCGCCTGGTGGCGCCCACCCGCCACGTCCCAGCCCACCGGTTCGTGGAGGAACACGCGGAG
CGAACGCCGGATGCCATCGCGCTCGAACTGGGGCAAGAGCGGCTCACGTATGGCGAGCTGAACCGCCGGGCCAACCGCGC
CGCGCACCAGCTCATCGCGATGGGCGCCGGCCCGGAGATGCTGGTGGCCCTGGCCGTGCCTCGGTCGTTCGAGATGCTCA
TCGGCCTGCTCGCCATCTGGAAGGCGGGGGCGGCCTACGTCCCGCTCGACCTCTCGTACCCGAAGGATCGGCTCGACGGA
ATCCTGGAGGACTCGGGCGCCGCGCTCATGGTGAGCACCCATGCGGCGGAGCAGAAGTGGCGCGCGCCGCAGGTGCGGAC
GCTCTGGCTGGACGAGCCCGCGGATGCCGCGCCCACCGGCAATCCCGACAGTGGCGTTCGCATGGAGAACGCCGCCTACG
TCATCTACACCTCGGGCTCCACGGGCAGACCCAAGGGCGTGATTCTGGAACACCGGGGGCTCGCGAACGTCATCGAGATG
CAGCGGCACGAACTGGGCGCCGACGCAGGCTGCGTCATGCTCCAGTTCTCCTCCATCTCCTTCGACGTCTCGGTCTGGGA
AATCGTCATGGCCCTGACCAACGGGGGCCGGCTCGTGGTGGCCCCCGCGGACACGCTGCTCGCGGGCGACGAACTGGCCA
AGGTGCTGCTGGCTCACGGCGTCACGCACATGGTGCTGCCTCCGACGTCGTATGCAGCGCTCCCCACCGACCGCGAGTAC
CCCGCGCTTCGCATGCTGACGTCCGCGGGAGAGGCCCTTCCGCCAGAGGTCGTCCACACGTGGGCGCGGCCCGGCGTCCT
GTTCGTCAACGCCTATGGCCCCACCGAGGTGTCCATCATCAGCACGCTCGGCCACTGCCGGCAGGACGACCCGGGAGCTC
CGCCCATCGGGCGCCCCGCCCTCAACCTGGAGGGGTACGCCCTGGACCGCCACGGCGCACTGCTGCCCATTGGCGTCCCG
GGCGAGCTGCACATCGGAGGCGTCGGTGTCGCCCGCGGTTACCTGAACCGCGAGGAGCTCACGCGCGAAAAGTTCATCCC
GCATCCGTTCAAGCCCGACGCACGGCTGTACCGGAGCGGAGACCTGGTCCGCTGGCGCAAGGATGGCAACCTCGAGTACC
TCGGGCGCATCGACCATCAGGTCAAGCTCCGTGGCTATCGCATCGAACTGGGTGAAATCGAAGCGGTGCTCGCCTCCTAC
CCCGGTGTGGCGAAGGCCGTGGCCAACGTTCATTCCGCGGGCGCCCAGGGGGGCGTGAAGGCCCTGATTGCCTACGTCGT
CTCGACCCAGCCCGTGGATGTGCACGCGCTCCGCGAGTACGCCCGGAAGAAGCTCCCGGAGTTCATGGTGCCCGCGCAGT
TCATCCACCTGGAGGAGCTGCCGTTGTCATCCAGCGGCAAGGTGGACAAGCGACGTCTACCGCCGCCGCGCTTCGAGGCG
TCCGCGAGCGAGACGCGCTTCGTGCCCCCGCGTACACCCACCGAGCAGACGCTGGCCTCGCTGTGGGAGTCGCTCCTGGA
GCGCCGCCCGATTGGCGCGGAGGACAACTTCTTCGACTTGGGCGGGCACTCGCTTCTGGCCGCGCAGGTCATGAGCCGCG
TGCGGAGGACATTCGGCGTCGACGTGCCCCTCTCCGCCATCTTCGAGCAGCCGACGCTGACGGCACTGGCGGCGGTGATT
GCCGCCAAGGAGGCCGCACCGCAGCTTCCTCCGCTGGTCCGACTGACGAGCCCCGGGGACCGGCCCCTTTCGTTCGCGCA
GGAGCGGCTGCGATTCCTCGCCGAGCTCGAAGGCCAGAGCGCGGCCTACAACATCCCCTTCGCGTTCACGTTGCGCGGCT
CGCTGGACGAGGCCGCGTTGCGACGGAGCCTCCAGCGCGTGCTGGAGCGCCATGAGGTCCTCCGGACGAACTTCCCGCTC
GTCGACGGTCTGCCGGTGGCCCGGGTGGCCGACGCGGTGCTCACGCTGACCACAGAGGACCTCCGCCACGCTGGCGCGGT
AAGCCTCGACCAGCGGCTGGCCGAGGAGTCCGCCCGGCCCTTCGCGCTGGACGTGGGCCCCGTGGTGCGCGTGCACCTGT
TCAAGCGCGCGGACGACGAACACGTGCTCCTCGTGGCCATGCACCACATCGTGTCCGACGGCTGGTCCTTCGGCGTGATG
ATGCGTGAGTTCTCCGCGTTCTACGCCGCGGAGGTCCGGGGTGAGCCCCTGGCGCTTCCGGACCTTCCCATCCAGTACAC
GGACTACGCGGCGTGGCAGCGGAGCTGGCTCGACGGCCAGGCCCGGGAACATCAACTCGGCCATTGGCGCAAGGCGCTCG
CGGGTGCGCCCGCCGTGCTGGACCTGCCTACTGACAGGCCCCGGCCCGCGGTCCGGAGTCACCGGGGTGCCACCGAGCCG
CTGGCGTTGGCGCCCGACGTGGCCCAGGCCCTCACCTCGCTCTGCCGTGAGCAAGGAGTGACGGCCTACATGGCATTGCT
CGCCGCCTTTGGCGCTTACCTGGGCCGGGTGAGTGGGCAGGACGACGTGGTCATCGGCTCACCGTTCGCGGGCCGCCGCA
TCGCGGAGACGGAGCCGCTCATCGGGTTCTTCGTGAACTCGCTGCCCCTGCGCATCGACCTGGGCGGAGAGCCCACGTTC
CTCGAGCTCCTCCAGCGTGTCCGCCGCCAGGTGCTCGACGCCCATGAGCACCAGGACGTCCCGTTCGAGAAGCTGGTCGA
GGTGCTCAAGCCGGAGCGCGTGCTCGGAACCAGTCCGCTCTTCCAGGTGATGCTCGCGTACCAGCAGACGCACACCGCGA
AGATGGCGCTGCCGGGCCTGGAGGTCACCCCGGTGGCCATCCCCAGCGGCGCCGCCAAGTTCGACCTCACCCTGACGCTG
TCCGAGACGGCCCAGGGGTTCGAAGGCGTGCTGGAATACGACCGCGACCTCTTCGACGCATGGCGCATCCAGGCAATGGT
GCGCCAGCTGACGGGCTTCATCACGCGGCTGGCCGCCGAGCCGCGGTCGAAGGTCGTGGATGTCGACCTGCTGGGCGCCG
AGGAGCGTGCCCGGCTCACGCCTCGCGCACCGGAGGCGGCACCGTCCCTGCCCGCCGTGCACGAGGTCATCGCGGCCCAG
GCGGCGAAGACGCCGACGGCCATCGCCGTCGAGGCCGAGGACGGCACCCTCACCTACGCGGCCCTGGAGGCCCGCGCGAA
GGCCGTTGCCCAGGCGCTGGTCCAACGCGGCGTCACGCCAGGAACACTGGTGGCCCTCGCCGTGGAACGCTCCGTGGGGA
TGATGGCGGGGCTGCTCGGCATCCTCAAGGCGGGCGCGGCCTACGTCCCGCTCGACCCGGCCTACCCCCGCGAGCGGCTG
ACGTTCATGCTCGAGGACAGCGGCGCGCGGGTGGTCATCACGCAAGCGCACCTCACCTCGCGGTTTCCGGGGACCGACGT
GGTGGTGCTCGGGGACGACACCCTGGAGTCGTTCGAGCCACGGAGCGGCGCGCTGGCGTACTGCCTGTTCACCTCCGGCT
CGACGGGGCAGCCCAAGGGCGTGCTGATTGAGCACTCCGCCCTGGCCAACCACATGGCGTGGATGGACGACGCCATGCCG
CTGGCTCACGAGGACCGGGTGCTCCAGCGCACGTCGCTCAGCTTCGACGCCTCCGTCTGGGAGCTGTTCGCCCCGCTGAT
GGTGGGTGCCCGGCTGGTGCTGGCGCCGCACGGCCTTGGCGCGGATACGGAGCACCTGGCCCGCGTGCTGCGCGAGCGCG
ACGTCTCCGTGCTCCAACTGGTGCCCTCGCTGCTGACGGCGCTGGTGGAGGAGCCCGGCTTCGCGAACCTCCCGGCGCTC
CGGCGCGTCTGCGTGGGTGGAGAGCCCCTGCCCTCCGCGACCGTCGCCACGCTCTTCAGCCGTTCGAAGGCGGAGGTGTG
GAACCTCTACGGACCGACAGAGGCGACCATCGATTCGCTGGCGCACCGGTGTCTGCCCGGACAGGTGGGCGCGCACGGCC
CGACCGAGCCCATTGGCCTGCCCATCCACCGGATGGAAGCGCTCATCCTGGATGGCAGGCTTCGCCCTGTCCCGGAGGGT
GTCCCCGGAGAGCTCTATCTCGCGGGGCCCGGCCTGGCGCGCGGCTACCTCAACCGCCCGGAGCTGACGCAGTCGCGCTT
CATCGAACACGCCTTCCCCGGAGGCCCGACGCTGCGCATGTACAAGACGGGTGACGTGGTCCGCCGGCTGGCGGATGGCA
CGTTCCTGTTCGTGGGCCGCGCCGACCGGCAGGTGAAGCTGCGCGGGCATCGCATCGAGCTGGGCGAGGTCGAAGCCGCC
ATTGCCCGGCACCCGGCGGTGCGTGAAGCCGTCGCGCTGGTGCGCGGCACGGGTGGAGACTCCCGGCTGGTGGCCTTCGT
GGTGCCCCATGCGTCCGCGCAGCGCCCCGAGCCCACCGAGCTCCGGAGCTTCGTCGAGCAGCAGCTCACGGCGAACATGG
TGCCTGGGCAGTTCGTCCTCCTGGACGCGCTGCCGCTCGCGCCCAACGGAAAGGTGGATACGCGAGCGCTGAGCGCGATG
GAGCTCGCCGACGCGCGCGTCACCGCCCTGGAGGGCCTGCCGCGTGATGCGCTGGAGCTGGAGATGGTCCGGCTCTTCGA
GGAGGTGCTCGGCGTGCGCGCCGTGGGCATCCACGACAGCTTCTTCGACCTGGGCGGCCACTCGCTGCTGGCGCTCAAGA
TGAAGCTCGCGGTGGAGAAGCGCCTGGGCCGCCCGCTTCCGCTGGTGTCCCTGTTCAGGAACCCGACGCCCGCGCAGCTC
ACGGCGGTCCTCCGGACCGAGAACGCGGCCGTCTCTCCGCTGGTGCCGCTCACCCCCGAGGCCCACGCACTCATGGCCGC
CGGCGCCGCGAACCCGAACCGGACGCCGGTGCTCTACCTGGTGCCCGGTGGAGGCTCGACGCCGTTCTACCTGTTGTCCC
TCGCCAGACACCTGGAAGGCGTCGCCGTGTTCGGCCTCCAGCCCCAGGGCCTGGATGGCGACGTGCCACCCCACGAGACG
GTGGAGGCCATCGCCACATGGTACGCGGACGCCATCCTGGCCATGCAGCCTGAAGGCCCCTACTCCGTCGGTGGACACTC
CATGGGCGGACACATCGCCTATGAGCTGGCCCAGGAGCTCAAGGCCCGCGGCCGCGAGGTGGGCGTCGTCGCCATGCTGG
ATACCCTGGCGCCCTTCCCCGACGTCACCCGGCCGCAGGGCGAGGGTTGGGACACGGCGCAGTGGATGCTCCACCTCGCC
GGCATCATGGAGGCGTTCTTCAACGTGAAGATCGACCTCGCCCTGCCCGAAGTGCGCGCCATGGGCGAAGCCGAGCGGCT
CCAGTTCTTCGTCGCACGGCTCCAGGCCGCGGCGGTCCTCCCCGAAGGCGCGCAGCCCGTCCACGTGCAGGGCATCCTCA
ACGTGGCGCGGGCCCATGACGCCCTGAACTACCGGCCCCGCCGTGGACAACCGGTGCCCCTGGCGGTGTTCCGTGCGGAG
GACCGCAGTGGCCCCAGCACGGCGGCGCTCGACGCGCTCGTGCAAGACGGCACGCTCGGCTGGAGCCAGTTGACGCAGCA
GGCCTGCTCGGCCTACCCCGTCCCTGGCACCCACCTGTCGCTGCTCCGCGATCCGCACGCGGCGGTGCTCGCCCAGCACC
TGCTCGCGCTCATTCCACGTCCGACACCCACCCCATGA

Upstream 100 bases:

>100_bases
TCCCGGCGGCGCGTCTGAGTGCCAAGGATTTGAAGCGCGTGCTCACGCTGACCAAGAAGCCGCGATGAGCCAGGTGGAAG
GTGAGGGGCAGGACAGCGCC

Downstream 100 bases:

>100_bases
ACGTCCACAACGTCCTGAAGCTCCTGCACCTCATCGCCGTCGTGGTGTTCCTGGGCGACATCGTCGTGACGGCCGTGTGG
CGGTTGCTCGCGGACAGGAC

Product: non-ribosomal peptide synthetase

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: Gramicidin S synthase II; ATP-dependent proline adenylase; ProA; Proline activase; ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent ornithine adenylase; OrnA; Ornithine activase; ATP-dependent leucine adenylase; LeuA; Leucine activase [H]

Number of amino acids: Translated: 4465; Mature: 4464

Protein sequence:

>4465_residues
MTSEESIEDIYELAPMQHGMLFHALMEPGAGMYVEQLSCEVRGDLPINRWKEAWQHVLARHPILRSGFLWEGLEKPLQVV
AVEAEVPWRIEDIRHVPEDAQQRWIDDFLREDRLQGFDLGTPPLIRCALIRLDDARHLFVWTYHHLLLDGWCFSIVLREV
LGAFEEGVAALPPAARPYRDYIAWLQEQDPSRAESFWRERLQGFKQPTPLPFTERQDTSEPAGDTQPEVTKRLSPELTAR
LTGFAKAHRLTLNTLVQGAWALVLARATGTDDVIFGVTVSGRPADLAGSESIVGLFINTLPLRARLDGTAPVATFLSGLQ
TEQGAVEPYSYASLADIQHWSDAPKDRPLFESILVFENYPLDASTLLPRSGLTISSVNTHDRISYPLALVAIPGESLELR
VMYAADAFSRPMAERIARLLEAALESLPGAKTVGDIDLMDEAARRVLAEWGQHPRAYDVTRPVTALLDGAAPDATAVVGP
DGQSISYRELDRRAERVARHLRQLGAGRERIVGVCIGRSVEMVVALLGVLKAGAAYLPLDPNYPAERLAYIVGDAAPVAI
LNTGADPIADTRVPRLDVSRVLNETATPDVPAKEPVQLDDLAYVIYTSGSTGAPKGVLVTHRNLMNLVSWHTEAFGLTAK
DRTTQLASTAFDASVWEIWPTLAAGATLHLVPPELSSAPSDLANWLVAQQISISFLPTVVAEAVLALQWPSPCALRFVLT
GGDRLHATPPAGLPFQLVNNYGPTETTVVATSGTVAPDGKQGLPSIGRPVANARIYILDRQRRPVLPGVIGELYIGGVGV
TRGYLNRPDLNVERFVPDPFAGVPEARMYASGDFARFLPDGTIAFHGRADRQVQIRGVRVELGEIEAALAAHPDVTAAAV
VSEAQRQNGDVRLIAFAVSDVVPQPDAAVLTQFLATKLPTAILPSRVIVIDRLPLTPNGKVDTAALEARALEAQPQVASA
APRTPHEEILAGIWSAVLGQERVGIHDDFFDLGGHSLKATQVIARTREAFGVDIPVRAIFERRTIAQLAETLSGQGTAVE
PIPHVELTGDTPVAPGQESLWFIDALGGDSAAYNVPLVLRLQGTLDGSALARTLQLLVERHEALRSTFHDRGGTPVLRVQ
APAASVLVSEDVSPALLDARIAEEVAAPFSLTDGPLFRARHFRLAPDNHVLVLNQHHIIADAWSVGVLLREFCIVYASLV
SGTEPALPALPIRYADWAAWQRQRLESGRLDESVAFWREALKDAPPVLPLPTDHPRPERQRFHGKTHGFVLDAPLGQRLE
ALSRSSGASLFMTLLGAFAAYLGRISGQEDVVIGSPVANRDRHETEGVVGYFLNTLALRVDLSGDPTFSELLLRVRKTAL
DAYAHQDVPFEKLVAALELPRGLAHNPLFQVMFVLQGQSGGELQLPDVRAEIQAPASSTSKFDLTFFVEPREGALACSIE
YDTDLFDADRIDRMAAHLGRLLQAIAEEPELHTSELPLLSNEERRLYADLNRTERRYTGRTLPELFERQAQRTPDVVALE
HQGETRTYRQLHEAAEALADRLGALGVGPGVRVSICLDRSIHAQVALLAVLKAGGAYVPLDPTYPPERLRYMLEDARPRV
LLTEKKYSELLPSQGLTQVLLDDTEAPATKTPRPRVEPHHLAYVLYTSGSTGKPKGVAMPHRALVNLIEWQTEHASPLRT
LQFAPLNFDVSFQETFSTWCSGGTLVLIDEGTRRDPDALADFLDVARVQRLFLPAVALHHLAQAALRTEHRVPGLTEVIT
AGDQLRITDPIRRWFQEGGKRLHNHYGPTESHVVTALELEGDPRHWPGLPSIGRPIANAAVHLLDANQRPVPVGVPGELY
LAGTCLADGYLSRPDLTAERFVELPLSPPVRAYRTGDLGRLTVDGSIEFLGRADDQVKIRGFRVEPGEIERALCAHPDVR
DAAVIVDGDATREKRLVAYVVPETVRLAELPDFLARDLPEYMVPALFVPMPELPRTPSGKVARRALPAPVAPVQAESPSE
PPRTPTEATVARAFEQVLGRGVVGREQDFFQLGGHSLLAMQVVSRIRGDVDAAFRVSDLFENPTIASLSRVLDARRGSQT
LTLARIEPAPEGAAIPLSFSQERLWFLDQLYPGTTAYNLPMALRLTGTLDVSAFQESLSDIVRRHPVLGMRFVERDGRVW
QEPRANQDVPFEQVTLGETSPEALRLLIAEEAARPFDLTNGPLFRAKLFCLDEAAHVVVATMHHTVGDGWSISVLVRELS
QLYAGRVSGQPVTLPELPVDYRDFAYQQRRHLQGEVLEQRLDHWRKTLHGAPSALDLPMDRPRPPRTSMRGATERIALGK
ALSEAIEALSLRTGGTSFMVLMGGFAAYLARITGQDDIVIGTPVANRDRAELESLIGFFVGTLPLRIDLSANPTFEELVA
RVRASALDAYAYQDVPLEKIVEALGVERNLSHAPLFQVMLMLQNTPEGHLSLPGLALEPIDLEIESAKFDLTLSFEPTRE
GLAGVIEYSTDLFDADRIERMVAHLQVLFADAVAHPEKRLSELALLPEQERGVVAAFTQGRLVAPTRHVPAHRFVEEHAE
RTPDAIALELGQERLTYGELNRRANRAAHQLIAMGAGPEMLVALAVPRSFEMLIGLLAIWKAGAAYVPLDLSYPKDRLDG
ILEDSGAALMVSTHAAEQKWRAPQVRTLWLDEPADAAPTGNPDSGVRMENAAYVIYTSGSTGRPKGVILEHRGLANVIEM
QRHELGADAGCVMLQFSSISFDVSVWEIVMALTNGGRLVVAPADTLLAGDELAKVLLAHGVTHMVLPPTSYAALPTDREY
PALRMLTSAGEALPPEVVHTWARPGVLFVNAYGPTEVSIISTLGHCRQDDPGAPPIGRPALNLEGYALDRHGALLPIGVP
GELHIGGVGVARGYLNREELTREKFIPHPFKPDARLYRSGDLVRWRKDGNLEYLGRIDHQVKLRGYRIELGEIEAVLASY
PGVAKAVANVHSAGAQGGVKALIAYVVSTQPVDVHALREYARKKLPEFMVPAQFIHLEELPLSSSGKVDKRRLPPPRFEA
SASETRFVPPRTPTEQTLASLWESLLERRPIGAEDNFFDLGGHSLLAAQVMSRVRRTFGVDVPLSAIFEQPTLTALAAVI
AAKEAAPQLPPLVRLTSPGDRPLSFAQERLRFLAELEGQSAAYNIPFAFTLRGSLDEAALRRSLQRVLERHEVLRTNFPL
VDGLPVARVADAVLTLTTEDLRHAGAVSLDQRLAEESARPFALDVGPVVRVHLFKRADDEHVLLVAMHHIVSDGWSFGVM
MREFSAFYAAEVRGEPLALPDLPIQYTDYAAWQRSWLDGQAREHQLGHWRKALAGAPAVLDLPTDRPRPAVRSHRGATEP
LALAPDVAQALTSLCREQGVTAYMALLAAFGAYLGRVSGQDDVVIGSPFAGRRIAETEPLIGFFVNSLPLRIDLGGEPTF
LELLQRVRRQVLDAHEHQDVPFEKLVEVLKPERVLGTSPLFQVMLAYQQTHTAKMALPGLEVTPVAIPSGAAKFDLTLTL
SETAQGFEGVLEYDRDLFDAWRIQAMVRQLTGFITRLAAEPRSKVVDVDLLGAEERARLTPRAPEAAPSLPAVHEVIAAQ
AAKTPTAIAVEAEDGTLTYAALEARAKAVAQALVQRGVTPGTLVALAVERSVGMMAGLLGILKAGAAYVPLDPAYPRERL
TFMLEDSGARVVITQAHLTSRFPGTDVVVLGDDTLESFEPRSGALAYCLFTSGSTGQPKGVLIEHSALANHMAWMDDAMP
LAHEDRVLQRTSLSFDASVWELFAPLMVGARLVLAPHGLGADTEHLARVLRERDVSVLQLVPSLLTALVEEPGFANLPAL
RRVCVGGEPLPSATVATLFSRSKAEVWNLYGPTEATIDSLAHRCLPGQVGAHGPTEPIGLPIHRMEALILDGRLRPVPEG
VPGELYLAGPGLARGYLNRPELTQSRFIEHAFPGGPTLRMYKTGDVVRRLADGTFLFVGRADRQVKLRGHRIELGEVEAA
IARHPAVREAVALVRGTGGDSRLVAFVVPHASAQRPEPTELRSFVEQQLTANMVPGQFVLLDALPLAPNGKVDTRALSAM
ELADARVTALEGLPRDALELEMVRLFEEVLGVRAVGIHDSFFDLGGHSLLALKMKLAVEKRLGRPLPLVSLFRNPTPAQL
TAVLRTENAAVSPLVPLTPEAHALMAAGAANPNRTPVLYLVPGGGSTPFYLLSLARHLEGVAVFGLQPQGLDGDVPPHET
VEAIATWYADAILAMQPEGPYSVGGHSMGGHIAYELAQELKARGREVGVVAMLDTLAPFPDVTRPQGEGWDTAQWMLHLA
GIMEAFFNVKIDLALPEVRAMGEAERLQFFVARLQAAAVLPEGAQPVHVQGILNVARAHDALNYRPRRGQPVPLAVFRAE
DRSGPSTAALDALVQDGTLGWSQLTQQACSAYPVPGTHLSLLRDPHAAVLAQHLLALIPRPTPTP

Sequences:

>Translated_4465_residues
MTSEESIEDIYELAPMQHGMLFHALMEPGAGMYVEQLSCEVRGDLPINRWKEAWQHVLARHPILRSGFLWEGLEKPLQVV
AVEAEVPWRIEDIRHVPEDAQQRWIDDFLREDRLQGFDLGTPPLIRCALIRLDDARHLFVWTYHHLLLDGWCFSIVLREV
LGAFEEGVAALPPAARPYRDYIAWLQEQDPSRAESFWRERLQGFKQPTPLPFTERQDTSEPAGDTQPEVTKRLSPELTAR
LTGFAKAHRLTLNTLVQGAWALVLARATGTDDVIFGVTVSGRPADLAGSESIVGLFINTLPLRARLDGTAPVATFLSGLQ
TEQGAVEPYSYASLADIQHWSDAPKDRPLFESILVFENYPLDASTLLPRSGLTISSVNTHDRISYPLALVAIPGESLELR
VMYAADAFSRPMAERIARLLEAALESLPGAKTVGDIDLMDEAARRVLAEWGQHPRAYDVTRPVTALLDGAAPDATAVVGP
DGQSISYRELDRRAERVARHLRQLGAGRERIVGVCIGRSVEMVVALLGVLKAGAAYLPLDPNYPAERLAYIVGDAAPVAI
LNTGADPIADTRVPRLDVSRVLNETATPDVPAKEPVQLDDLAYVIYTSGSTGAPKGVLVTHRNLMNLVSWHTEAFGLTAK
DRTTQLASTAFDASVWEIWPTLAAGATLHLVPPELSSAPSDLANWLVAQQISISFLPTVVAEAVLALQWPSPCALRFVLT
GGDRLHATPPAGLPFQLVNNYGPTETTVVATSGTVAPDGKQGLPSIGRPVANARIYILDRQRRPVLPGVIGELYIGGVGV
TRGYLNRPDLNVERFVPDPFAGVPEARMYASGDFARFLPDGTIAFHGRADRQVQIRGVRVELGEIEAALAAHPDVTAAAV
VSEAQRQNGDVRLIAFAVSDVVPQPDAAVLTQFLATKLPTAILPSRVIVIDRLPLTPNGKVDTAALEARALEAQPQVASA
APRTPHEEILAGIWSAVLGQERVGIHDDFFDLGGHSLKATQVIARTREAFGVDIPVRAIFERRTIAQLAETLSGQGTAVE
PIPHVELTGDTPVAPGQESLWFIDALGGDSAAYNVPLVLRLQGTLDGSALARTLQLLVERHEALRSTFHDRGGTPVLRVQ
APAASVLVSEDVSPALLDARIAEEVAAPFSLTDGPLFRARHFRLAPDNHVLVLNQHHIIADAWSVGVLLREFCIVYASLV
SGTEPALPALPIRYADWAAWQRQRLESGRLDESVAFWREALKDAPPVLPLPTDHPRPERQRFHGKTHGFVLDAPLGQRLE
ALSRSSGASLFMTLLGAFAAYLGRISGQEDVVIGSPVANRDRHETEGVVGYFLNTLALRVDLSGDPTFSELLLRVRKTAL
DAYAHQDVPFEKLVAALELPRGLAHNPLFQVMFVLQGQSGGELQLPDVRAEIQAPASSTSKFDLTFFVEPREGALACSIE
YDTDLFDADRIDRMAAHLGRLLQAIAEEPELHTSELPLLSNEERRLYADLNRTERRYTGRTLPELFERQAQRTPDVVALE
HQGETRTYRQLHEAAEALADRLGALGVGPGVRVSICLDRSIHAQVALLAVLKAGGAYVPLDPTYPPERLRYMLEDARPRV
LLTEKKYSELLPSQGLTQVLLDDTEAPATKTPRPRVEPHHLAYVLYTSGSTGKPKGVAMPHRALVNLIEWQTEHASPLRT
LQFAPLNFDVSFQETFSTWCSGGTLVLIDEGTRRDPDALADFLDVARVQRLFLPAVALHHLAQAALRTEHRVPGLTEVIT
AGDQLRITDPIRRWFQEGGKRLHNHYGPTESHVVTALELEGDPRHWPGLPSIGRPIANAAVHLLDANQRPVPVGVPGELY
LAGTCLADGYLSRPDLTAERFVELPLSPPVRAYRTGDLGRLTVDGSIEFLGRADDQVKIRGFRVEPGEIERALCAHPDVR
DAAVIVDGDATREKRLVAYVVPETVRLAELPDFLARDLPEYMVPALFVPMPELPRTPSGKVARRALPAPVAPVQAESPSE
PPRTPTEATVARAFEQVLGRGVVGREQDFFQLGGHSLLAMQVVSRIRGDVDAAFRVSDLFENPTIASLSRVLDARRGSQT
LTLARIEPAPEGAAIPLSFSQERLWFLDQLYPGTTAYNLPMALRLTGTLDVSAFQESLSDIVRRHPVLGMRFVERDGRVW
QEPRANQDVPFEQVTLGETSPEALRLLIAEEAARPFDLTNGPLFRAKLFCLDEAAHVVVATMHHTVGDGWSISVLVRELS
QLYAGRVSGQPVTLPELPVDYRDFAYQQRRHLQGEVLEQRLDHWRKTLHGAPSALDLPMDRPRPPRTSMRGATERIALGK
ALSEAIEALSLRTGGTSFMVLMGGFAAYLARITGQDDIVIGTPVANRDRAELESLIGFFVGTLPLRIDLSANPTFEELVA
RVRASALDAYAYQDVPLEKIVEALGVERNLSHAPLFQVMLMLQNTPEGHLSLPGLALEPIDLEIESAKFDLTLSFEPTRE
GLAGVIEYSTDLFDADRIERMVAHLQVLFADAVAHPEKRLSELALLPEQERGVVAAFTQGRLVAPTRHVPAHRFVEEHAE
RTPDAIALELGQERLTYGELNRRANRAAHQLIAMGAGPEMLVALAVPRSFEMLIGLLAIWKAGAAYVPLDLSYPKDRLDG
ILEDSGAALMVSTHAAEQKWRAPQVRTLWLDEPADAAPTGNPDSGVRMENAAYVIYTSGSTGRPKGVILEHRGLANVIEM
QRHELGADAGCVMLQFSSISFDVSVWEIVMALTNGGRLVVAPADTLLAGDELAKVLLAHGVTHMVLPPTSYAALPTDREY
PALRMLTSAGEALPPEVVHTWARPGVLFVNAYGPTEVSIISTLGHCRQDDPGAPPIGRPALNLEGYALDRHGALLPIGVP
GELHIGGVGVARGYLNREELTREKFIPHPFKPDARLYRSGDLVRWRKDGNLEYLGRIDHQVKLRGYRIELGEIEAVLASY
PGVAKAVANVHSAGAQGGVKALIAYVVSTQPVDVHALREYARKKLPEFMVPAQFIHLEELPLSSSGKVDKRRLPPPRFEA
SASETRFVPPRTPTEQTLASLWESLLERRPIGAEDNFFDLGGHSLLAAQVMSRVRRTFGVDVPLSAIFEQPTLTALAAVI
AAKEAAPQLPPLVRLTSPGDRPLSFAQERLRFLAELEGQSAAYNIPFAFTLRGSLDEAALRRSLQRVLERHEVLRTNFPL
VDGLPVARVADAVLTLTTEDLRHAGAVSLDQRLAEESARPFALDVGPVVRVHLFKRADDEHVLLVAMHHIVSDGWSFGVM
MREFSAFYAAEVRGEPLALPDLPIQYTDYAAWQRSWLDGQAREHQLGHWRKALAGAPAVLDLPTDRPRPAVRSHRGATEP
LALAPDVAQALTSLCREQGVTAYMALLAAFGAYLGRVSGQDDVVIGSPFAGRRIAETEPLIGFFVNSLPLRIDLGGEPTF
LELLQRVRRQVLDAHEHQDVPFEKLVEVLKPERVLGTSPLFQVMLAYQQTHTAKMALPGLEVTPVAIPSGAAKFDLTLTL
SETAQGFEGVLEYDRDLFDAWRIQAMVRQLTGFITRLAAEPRSKVVDVDLLGAEERARLTPRAPEAAPSLPAVHEVIAAQ
AAKTPTAIAVEAEDGTLTYAALEARAKAVAQALVQRGVTPGTLVALAVERSVGMMAGLLGILKAGAAYVPLDPAYPRERL
TFMLEDSGARVVITQAHLTSRFPGTDVVVLGDDTLESFEPRSGALAYCLFTSGSTGQPKGVLIEHSALANHMAWMDDAMP
LAHEDRVLQRTSLSFDASVWELFAPLMVGARLVLAPHGLGADTEHLARVLRERDVSVLQLVPSLLTALVEEPGFANLPAL
RRVCVGGEPLPSATVATLFSRSKAEVWNLYGPTEATIDSLAHRCLPGQVGAHGPTEPIGLPIHRMEALILDGRLRPVPEG
VPGELYLAGPGLARGYLNRPELTQSRFIEHAFPGGPTLRMYKTGDVVRRLADGTFLFVGRADRQVKLRGHRIELGEVEAA
IARHPAVREAVALVRGTGGDSRLVAFVVPHASAQRPEPTELRSFVEQQLTANMVPGQFVLLDALPLAPNGKVDTRALSAM
ELADARVTALEGLPRDALELEMVRLFEEVLGVRAVGIHDSFFDLGGHSLLALKMKLAVEKRLGRPLPLVSLFRNPTPAQL
TAVLRTENAAVSPLVPLTPEAHALMAAGAANPNRTPVLYLVPGGGSTPFYLLSLARHLEGVAVFGLQPQGLDGDVPPHET
VEAIATWYADAILAMQPEGPYSVGGHSMGGHIAYELAQELKARGREVGVVAMLDTLAPFPDVTRPQGEGWDTAQWMLHLA
GIMEAFFNVKIDLALPEVRAMGEAERLQFFVARLQAAAVLPEGAQPVHVQGILNVARAHDALNYRPRRGQPVPLAVFRAE
DRSGPSTAALDALVQDGTLGWSQLTQQACSAYPVPGTHLSLLRDPHAAVLAQHLLALIPRPTPTP
>Mature_4464_residues
TSEESIEDIYELAPMQHGMLFHALMEPGAGMYVEQLSCEVRGDLPINRWKEAWQHVLARHPILRSGFLWEGLEKPLQVVA
VEAEVPWRIEDIRHVPEDAQQRWIDDFLREDRLQGFDLGTPPLIRCALIRLDDARHLFVWTYHHLLLDGWCFSIVLREVL
GAFEEGVAALPPAARPYRDYIAWLQEQDPSRAESFWRERLQGFKQPTPLPFTERQDTSEPAGDTQPEVTKRLSPELTARL
TGFAKAHRLTLNTLVQGAWALVLARATGTDDVIFGVTVSGRPADLAGSESIVGLFINTLPLRARLDGTAPVATFLSGLQT
EQGAVEPYSYASLADIQHWSDAPKDRPLFESILVFENYPLDASTLLPRSGLTISSVNTHDRISYPLALVAIPGESLELRV
MYAADAFSRPMAERIARLLEAALESLPGAKTVGDIDLMDEAARRVLAEWGQHPRAYDVTRPVTALLDGAAPDATAVVGPD
GQSISYRELDRRAERVARHLRQLGAGRERIVGVCIGRSVEMVVALLGVLKAGAAYLPLDPNYPAERLAYIVGDAAPVAIL
NTGADPIADTRVPRLDVSRVLNETATPDVPAKEPVQLDDLAYVIYTSGSTGAPKGVLVTHRNLMNLVSWHTEAFGLTAKD
RTTQLASTAFDASVWEIWPTLAAGATLHLVPPELSSAPSDLANWLVAQQISISFLPTVVAEAVLALQWPSPCALRFVLTG
GDRLHATPPAGLPFQLVNNYGPTETTVVATSGTVAPDGKQGLPSIGRPVANARIYILDRQRRPVLPGVIGELYIGGVGVT
RGYLNRPDLNVERFVPDPFAGVPEARMYASGDFARFLPDGTIAFHGRADRQVQIRGVRVELGEIEAALAAHPDVTAAAVV
SEAQRQNGDVRLIAFAVSDVVPQPDAAVLTQFLATKLPTAILPSRVIVIDRLPLTPNGKVDTAALEARALEAQPQVASAA
PRTPHEEILAGIWSAVLGQERVGIHDDFFDLGGHSLKATQVIARTREAFGVDIPVRAIFERRTIAQLAETLSGQGTAVEP
IPHVELTGDTPVAPGQESLWFIDALGGDSAAYNVPLVLRLQGTLDGSALARTLQLLVERHEALRSTFHDRGGTPVLRVQA
PAASVLVSEDVSPALLDARIAEEVAAPFSLTDGPLFRARHFRLAPDNHVLVLNQHHIIADAWSVGVLLREFCIVYASLVS
GTEPALPALPIRYADWAAWQRQRLESGRLDESVAFWREALKDAPPVLPLPTDHPRPERQRFHGKTHGFVLDAPLGQRLEA
LSRSSGASLFMTLLGAFAAYLGRISGQEDVVIGSPVANRDRHETEGVVGYFLNTLALRVDLSGDPTFSELLLRVRKTALD
AYAHQDVPFEKLVAALELPRGLAHNPLFQVMFVLQGQSGGELQLPDVRAEIQAPASSTSKFDLTFFVEPREGALACSIEY
DTDLFDADRIDRMAAHLGRLLQAIAEEPELHTSELPLLSNEERRLYADLNRTERRYTGRTLPELFERQAQRTPDVVALEH
QGETRTYRQLHEAAEALADRLGALGVGPGVRVSICLDRSIHAQVALLAVLKAGGAYVPLDPTYPPERLRYMLEDARPRVL
LTEKKYSELLPSQGLTQVLLDDTEAPATKTPRPRVEPHHLAYVLYTSGSTGKPKGVAMPHRALVNLIEWQTEHASPLRTL
QFAPLNFDVSFQETFSTWCSGGTLVLIDEGTRRDPDALADFLDVARVQRLFLPAVALHHLAQAALRTEHRVPGLTEVITA
GDQLRITDPIRRWFQEGGKRLHNHYGPTESHVVTALELEGDPRHWPGLPSIGRPIANAAVHLLDANQRPVPVGVPGELYL
AGTCLADGYLSRPDLTAERFVELPLSPPVRAYRTGDLGRLTVDGSIEFLGRADDQVKIRGFRVEPGEIERALCAHPDVRD
AAVIVDGDATREKRLVAYVVPETVRLAELPDFLARDLPEYMVPALFVPMPELPRTPSGKVARRALPAPVAPVQAESPSEP
PRTPTEATVARAFEQVLGRGVVGREQDFFQLGGHSLLAMQVVSRIRGDVDAAFRVSDLFENPTIASLSRVLDARRGSQTL
TLARIEPAPEGAAIPLSFSQERLWFLDQLYPGTTAYNLPMALRLTGTLDVSAFQESLSDIVRRHPVLGMRFVERDGRVWQ
EPRANQDVPFEQVTLGETSPEALRLLIAEEAARPFDLTNGPLFRAKLFCLDEAAHVVVATMHHTVGDGWSISVLVRELSQ
LYAGRVSGQPVTLPELPVDYRDFAYQQRRHLQGEVLEQRLDHWRKTLHGAPSALDLPMDRPRPPRTSMRGATERIALGKA
LSEAIEALSLRTGGTSFMVLMGGFAAYLARITGQDDIVIGTPVANRDRAELESLIGFFVGTLPLRIDLSANPTFEELVAR
VRASALDAYAYQDVPLEKIVEALGVERNLSHAPLFQVMLMLQNTPEGHLSLPGLALEPIDLEIESAKFDLTLSFEPTREG
LAGVIEYSTDLFDADRIERMVAHLQVLFADAVAHPEKRLSELALLPEQERGVVAAFTQGRLVAPTRHVPAHRFVEEHAER
TPDAIALELGQERLTYGELNRRANRAAHQLIAMGAGPEMLVALAVPRSFEMLIGLLAIWKAGAAYVPLDLSYPKDRLDGI
LEDSGAALMVSTHAAEQKWRAPQVRTLWLDEPADAAPTGNPDSGVRMENAAYVIYTSGSTGRPKGVILEHRGLANVIEMQ
RHELGADAGCVMLQFSSISFDVSVWEIVMALTNGGRLVVAPADTLLAGDELAKVLLAHGVTHMVLPPTSYAALPTDREYP
ALRMLTSAGEALPPEVVHTWARPGVLFVNAYGPTEVSIISTLGHCRQDDPGAPPIGRPALNLEGYALDRHGALLPIGVPG
ELHIGGVGVARGYLNREELTREKFIPHPFKPDARLYRSGDLVRWRKDGNLEYLGRIDHQVKLRGYRIELGEIEAVLASYP
GVAKAVANVHSAGAQGGVKALIAYVVSTQPVDVHALREYARKKLPEFMVPAQFIHLEELPLSSSGKVDKRRLPPPRFEAS
ASETRFVPPRTPTEQTLASLWESLLERRPIGAEDNFFDLGGHSLLAAQVMSRVRRTFGVDVPLSAIFEQPTLTALAAVIA
AKEAAPQLPPLVRLTSPGDRPLSFAQERLRFLAELEGQSAAYNIPFAFTLRGSLDEAALRRSLQRVLERHEVLRTNFPLV
DGLPVARVADAVLTLTTEDLRHAGAVSLDQRLAEESARPFALDVGPVVRVHLFKRADDEHVLLVAMHHIVSDGWSFGVMM
REFSAFYAAEVRGEPLALPDLPIQYTDYAAWQRSWLDGQAREHQLGHWRKALAGAPAVLDLPTDRPRPAVRSHRGATEPL
ALAPDVAQALTSLCREQGVTAYMALLAAFGAYLGRVSGQDDVVIGSPFAGRRIAETEPLIGFFVNSLPLRIDLGGEPTFL
ELLQRVRRQVLDAHEHQDVPFEKLVEVLKPERVLGTSPLFQVMLAYQQTHTAKMALPGLEVTPVAIPSGAAKFDLTLTLS
ETAQGFEGVLEYDRDLFDAWRIQAMVRQLTGFITRLAAEPRSKVVDVDLLGAEERARLTPRAPEAAPSLPAVHEVIAAQA
AKTPTAIAVEAEDGTLTYAALEARAKAVAQALVQRGVTPGTLVALAVERSVGMMAGLLGILKAGAAYVPLDPAYPRERLT
FMLEDSGARVVITQAHLTSRFPGTDVVVLGDDTLESFEPRSGALAYCLFTSGSTGQPKGVLIEHSALANHMAWMDDAMPL
AHEDRVLQRTSLSFDASVWELFAPLMVGARLVLAPHGLGADTEHLARVLRERDVSVLQLVPSLLTALVEEPGFANLPALR
RVCVGGEPLPSATVATLFSRSKAEVWNLYGPTEATIDSLAHRCLPGQVGAHGPTEPIGLPIHRMEALILDGRLRPVPEGV
PGELYLAGPGLARGYLNRPELTQSRFIEHAFPGGPTLRMYKTGDVVRRLADGTFLFVGRADRQVKLRGHRIELGEVEAAI
ARHPAVREAVALVRGTGGDSRLVAFVVPHASAQRPEPTELRSFVEQQLTANMVPGQFVLLDALPLAPNGKVDTRALSAME
LADARVTALEGLPRDALELEMVRLFEEVLGVRAVGIHDSFFDLGGHSLLALKMKLAVEKRLGRPLPLVSLFRNPTPAQLT
AVLRTENAAVSPLVPLTPEAHALMAAGAANPNRTPVLYLVPGGGSTPFYLLSLARHLEGVAVFGLQPQGLDGDVPPHETV
EAIATWYADAILAMQPEGPYSVGGHSMGGHIAYELAQELKARGREVGVVAMLDTLAPFPDVTRPQGEGWDTAQWMLHLAG
IMEAFFNVKIDLALPEVRAMGEAERLQFFVARLQAAAVLPEGAQPVHVQGILNVARAHDALNYRPRRGQPVPLAVFRAED
RSGPSTAALDALVQDGTLGWSQLTQQACSAYPVPGTHLSLLRDPHAAVLAQHLLALIPRPTPTP

Specific function: This protein is a multifunctional enzyme, able to activate and polymerize the amino acids Pro, Val, Orn and Leu. Activation sites for these AA consist of individual domains [H]

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=443, Percent_Identity=28.4424379232506, Blast_Score=127, Evalue=2e-28,
Organism=Homo sapiens, GI38505220, Length=509, Percent_Identity=25.147347740668, Blast_Score=114, Evalue=2e-24,
Organism=Homo sapiens, GI122937307, Length=423, Percent_Identity=26.0047281323877, Blast_Score=98, Evalue=2e-19,
Organism=Homo sapiens, GI187761345, Length=539, Percent_Identity=26.1595547309833, Blast_Score=96, Evalue=1e-18,
Organism=Homo sapiens, GI187761343, Length=539, Percent_Identity=26.1595547309833, Blast_Score=96, Evalue=1e-18,
Organism=Homo sapiens, GI42544132, Length=509, Percent_Identity=22.7897838899804, Blast_Score=92, Evalue=8e-18,
Organism=Homo sapiens, GI58082049, Length=538, Percent_Identity=21.9330855018587, Blast_Score=92, Evalue=9e-18,
Organism=Homo sapiens, GI157311624, Length=539, Percent_Identity=20.7792207792208, Blast_Score=90, Evalue=5e-17,
Organism=Homo sapiens, GI157311622, Length=539, Percent_Identity=20.7792207792208, Blast_Score=90, Evalue=5e-17,
Organism=Homo sapiens, GI156151445, Length=538, Percent_Identity=22.8624535315985, Blast_Score=87, Evalue=4e-16,
Organism=Homo sapiens, GI115511026, Length=373, Percent_Identity=24.9329758713137, Blast_Score=84, Evalue=5e-15,
Organism=Homo sapiens, GI13375727, Length=534, Percent_Identity=23.0337078651685, Blast_Score=76, Evalue=8e-13,
Organism=Escherichia coli, GI1786801, Length=1206, Percent_Identity=30.5970149253731, Blast_Score=414, Evalue=1e-116,
Organism=Escherichia coli, GI1788107, Length=547, Percent_Identity=25.9597806215722, Blast_Score=138, Evalue=1e-32,
Organism=Escherichia coli, GI145693145, Length=556, Percent_Identity=26.6187050359712, Blast_Score=138, Evalue=1e-32,
Organism=Escherichia coli, GI1786810, Length=529, Percent_Identity=27.5992438563327, Blast_Score=108, Evalue=8e-24,
Organism=Escherichia coli, GI221142682, Length=503, Percent_Identity=25.844930417495, Blast_Score=102, Evalue=6e-22,
Organism=Escherichia coli, GI1786529, Length=570, Percent_Identity=25.2631578947368, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1790505, Length=581, Percent_Identity=23.0636833046472, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI1789201, Length=366, Percent_Identity=27.0491803278689, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17550940, Length=1281, Percent_Identity=23.4192037470726, Blast_Score=252, Evalue=3e-66,
Organism=Caenorhabditis elegans, GI17556356, Length=1165, Percent_Identity=24.549356223176, Blast_Score=223, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI17538037, Length=554, Percent_Identity=24.7292418772563, Blast_Score=104, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17557194, Length=544, Percent_Identity=23.7132352941176, Blast_Score=102, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17559526, Length=509, Percent_Identity=23.9685658153242, Blast_Score=97, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI32564422, Length=507, Percent_Identity=25.2465483234714, Blast_Score=97, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI32564420, Length=507, Percent_Identity=25.2465483234714, Blast_Score=97, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17558820, Length=508, Percent_Identity=23.8188976377953, Blast_Score=89, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17560140, Length=518, Percent_Identity=21.8146718146718, Blast_Score=86, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71982997, Length=573, Percent_Identity=25.4799301919721, Blast_Score=84, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71983001, Length=573, Percent_Identity=25.4799301919721, Blast_Score=84, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17531443, Length=539, Percent_Identity=21.7068645640074, Blast_Score=77, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71985884, Length=375, Percent_Identity=22.4, Blast_Score=77, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319591, Length=940, Percent_Identity=26.1702127659574, Blast_Score=239, Evalue=8e-63,
Organism=Saccharomyces cerevisiae, GI6319264, Length=560, Percent_Identity=25.8928571428571, Blast_Score=97, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6319699, Length=529, Percent_Identity=21.9281663516068, Blast_Score=89, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24648676, Length=564, Percent_Identity=32.8014184397163, Blast_Score=224, Evalue=8e-58,
Organism=Drosophila melanogaster, GI24582852, Length=523, Percent_Identity=24.4741873804971, Blast_Score=105, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24581924, Length=565, Percent_Identity=24.4247787610619, Blast_Score=100, Evalue=2e-20,
Organism=Drosophila melanogaster, GI19922652, Length=532, Percent_Identity=23.3082706766917, Blast_Score=99, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24656500, Length=503, Percent_Identity=22.8628230616302, Blast_Score=89, Evalue=8e-17,
Organism=Drosophila melanogaster, GI18859661, Length=524, Percent_Identity=23.6641221374046, Blast_Score=85, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24667955, Length=543, Percent_Identity=22.8360957642726, Blast_Score=81, Evalue=2e-14,
Organism=Drosophila melanogaster, GI62472339, Length=543, Percent_Identity=22.8360957642726, Blast_Score=81, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24648260, Length=482, Percent_Identity=22.6141078838174, Blast_Score=80, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21355181, Length=499, Percent_Identity=24.248496993988, Blast_Score=78, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24648257, Length=530, Percent_Identity=24.1509433962264, Blast_Score=75, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24667959, Length=379, Percent_Identity=25.065963060686, Blast_Score=74, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR006163
- InterPro:   IPR006162
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 486831; Mature: 486700

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSEESIEDIYELAPMQHGMLFHALMEPGAGMYVEQLSCEVRGDLPINRWKEAWQHVLAR
CCCHHHHHHHHHHCCHHCCHHHHHHHCCCCCCCHHHHCCEECCCCCHHHHHHHHHHHHHH
HPILRSGFLWEGLEKPLQVVAVEAEVPWRIEDIRHVPEDAQQRWIDDFLREDRLQGFDLG
CCHHHCCCHHHHHHCCEEEEEEECCCCEEHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCC
TPPLIRCALIRLDDARHLFVWTYHHLLLDGWCFSIVLREVLGAFEEGVAALPPAARPYRD
CCHHHHEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
YIAWLQEQDPSRAESFWRERLQGFKQPTPLPFTERQDTSEPAGDTQPEVTKRLSPELTAR
HHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHH
LTGFAKAHRLTLNTLVQGAWALVLARATGTDDVIFGVTVSGRPADLAGSESIVGLFINTL
HHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEEEECCCCCCCCCCCCEEEHHHHCC
PLRARLDGTAPVATFLSGLQTEQGAVEPYSYASLADIQHWSDAPKDRPLFESILVFENYP
CCEEECCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCC
LDASTLLPRSGLTISSVNTHDRISYPLALVAIPGESLELRVMYAADAFSRPMAERIARLL
CCHHHCCCCCCCEEEECCCCCCCCCCEEEEEECCCCEEEEEEEECCHHCCHHHHHHHHHH
EAALESLPGAKTVGDIDLMDEAARRVLAEWGQHPRAYDVTRPVTALLDGAAPDATAVVGP
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCEEEECC
DGQSISYRELDRRAERVARHLRQLGAGRERIVGVCIGRSVEMVVALLGVLKAGAAYLPLD
CCCCCCHHHHHHHHHHHHHHHHHHCCCHHHEEEEECCCCHHHHHHHHHHHHCCCEEECCC
PNYPAERLAYIVGDAAPVAILNTGADPIADTRVPRLDVSRVLNETATPDVPAKEPVQLDD
CCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCC
LAYVIYTSGSTGAPKGVLVTHRNLMNLVSWHTEAFGLTAKDRTTQLASTAFDASVWEIWP
EEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHH
TLAAGATLHLVPPELSSAPSDLANWLVAQQISISFLPTVVAEAVLALQWPSPCALRFVLT
HHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
GGDRLHATPPAGLPFQLVNNYGPTETTVVATSGTVAPDGKQGLPSIGRPVANARIYILDR
CCCEEECCCCCCCCHHHHCCCCCCCEEEEEECCCCCCCCCCCCCHHCCCCCCCEEEEEEC
QRRPVLPGVIGELYIGGVGVTRGYLNRPDLNVERFVPDPFAGVPEARMYASGDFARFLPD
CCCCCCCHHHHHHHCCCEEHCCCCCCCCCCCHHHCCCCCCCCCCCCCEECCCCHHHHCCC
GTIAFHGRADRQVQIRGVRVELGEIEAALAAHPDVTAAAVVSEAQRQNGDVRLIAFAVSD
CCEEECCCCCCEEEEEEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEEEHH
VVPQPDAAVLTQFLATKLPTAILPSRVIVIDRLPLTPNGKVDTAALEARALEAQPQVASA
CCCCCCHHHHHHHHHHHCCHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCHHCC
APRTPHEEILAGIWSAVLGQERVGIHDDFFDLGGHSLKATQVIARTREAFGVDIPVRAIF
CCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHH
ERRTIAQLAETLSGQGTAVEPIPHVELTGDTPVAPGQESLWFIDALGGDSAAYNVPLVLR
HHHHHHHHHHHHCCCCCEECCCCCEEECCCCCCCCCCCCEEEEEECCCCCCEECCCEEEE
LQGTLDGSALARTLQLLVERHEALRSTFHDRGGTPVLRVQAPAASVLVSEDVSPALLDAR
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHEEEECCCCHHHHHHH
IAEEVAAPFSLTDGPLFRARHFRLAPDNHVLVLNQHHIIADAWSVGVLLREFCIVYASLV
HHHHHCCCCCCCCCCCCCCEEEEECCCCEEEEEECCEEEEHHHHHHHHHHHHHHHHHHHH
SGTEPALPALPIRYADWAAWQRQRLESGRLDESVAFWREALKDAPPVLPLPTDHPRPERQ
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
RFHGKTHGFVLDAPLGQRLEALSRSSGASLFMTLLGAFAAYLGRISGQEDVVIGSPVANR
HHCCCCCCEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCC
DRHETEGVVGYFLNTLALRVDLSGDPTFSELLLRVRKTALDAYAHQDVPFEKLVAALELP
CCCHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
RGLAHNPLFQVMFVLQGQSGGELQLPDVRAEIQAPASSTSKFDLTFFVEPREGALACSIE
CCCCCCHHHHHHHHEECCCCCCEECCCHHHHHCCCCCCCCEEEEEEEEECCCCCEEEEEE
YDTDLFDADRIDRMAAHLGRLLQAIAEEPELHTSELPLLSNEERRLYADLNRTERRYTGR
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
TLPELFERQAQRTPDVVALEHQGETRTYRQLHEAAEALADRLGALGVGPGVRVSICLDRS
CHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCC
IHAQVALLAVLKAGGAYVPLDPTYPPERLRYMLEDARPRVLLTEKKYSELLPSQGLTQVL
HHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHCCCCCEEEECHHHHHHCCCCCCHHHH
LDDTEAPATKTPRPRVEPHHLAYVLYTSGSTGKPKGVAMPHRALVNLIEWQTEHASPLRT
HCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCE
LQFAPLNFDVSFQETFSTWCSGGTLVLIDEGTRRDPDALADFLDVARVQRLFLPAVALHH
EEECCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LAQAALRTEHRVPGLTEVITAGDQLRITDPIRRWFQEGGKRLHNHYGPTESHVVTALELE
HHHHHHHHHCCCCCHHHHHCCCCCEEECHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEC
GDPRHWPGLPSIGRPIANAAVHLLDANQRPVPVGVPGELYLAGTCLADGYLSRPDLTAER
CCCCCCCCCCCCCCHHHHHHEEEEECCCCCCEECCCCCEEEEEEECCCCCCCCCCCCHHH
FVELPLSPPVRAYRTGDLGRLTVDGSIEFLGRADDQVKIRGFRVEPGEIERALCAHPDVR
HEECCCCCCCHHEECCCCEEEEECCCEEEECCCCCEEEEEEEECCCHHHHHHHHCCCCCC
DAAVIVDGDATREKRLVAYVVPETVRLAELPDFLARDLPEYMVPALFVPMPELPRTPSGK
CEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCH
VARRALPAPVAPVQAESPSEPPRTPTEATVARAFEQVLGRGVVGREQDFFQLGGHSLLAM
HHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCHHHHH
QVVSRIRGDVDAAFRVSDLFENPTIASLSRVLDARRGSQTLTLARIEPAPEGAAIPLSFS
HHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEECCCC
QERLWFLDQLYPGTTAYNLPMALRLTGTLDVSAFQESLSDIVRRHPVLGMRFVERDGRVW
CHHHHHHHHHCCCCEEECCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCC
QEPRANQDVPFEQVTLGETSPEALRLLIAEEAARPFDLTNGPLFRAKLFCLDEAAHVVVA
CCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEHHHHHHHHHE
TMHHTVGDGWSISVLVRELSQLYAGRVSGQPVTLPELPVDYRDFAYQQRRHLQGEVLEQR
EHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHH
LDHWRKTLHGAPSALDLPMDRPRPPRTSMRGATERIALGKALSEAIEALSLRTGGTSFMV
HHHHHHHHCCCCCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHH
LMGGFAAYLARITGQDDIVIGTPVANRDRAELESLIGFFVGTLPLRIDLSANPTFEELVA
HHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHH
RVRASALDAYAYQDVPLEKIVEALGVERNLSHAPLFQVMLMLQNTPEGHLSLPGLALEPI
HHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCEECCCCEECCC
DLEIESAKFDLTLSFEPTREGLAGVIEYSTDLFDADRIERMVAHLQVLFADAVAHPEKRL
CEEEECCEEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHH
SELALLPEQERGVVAAFTQGRLVAPTRHVPAHRFVEEHAERTPDAIALELGQERLTYGEL
HHHHCCCCCCCCEEEEECCCEEECCCCCCCHHHHHHHHHHCCCCCEEEHHCHHHHHHHHH
NRRANRAAHQLIAMGAGPEMLVALAVPRSFEMLIGLLAIWKAGAAYVPLDLSYPKDRLDG
HHHHHHHHHHHHHCCCCHHEEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHH
ILEDSGAALMVSTHAAEQKWRAPQVRTLWLDEPADAAPTGNPDSGVRMENAAYVIYTSGS
HHCCCCCEEEEEEHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCEEEECCEEEEEECCC
TGRPKGVILEHRGLANVIEMQRHELGADAGCVMLQFSSISFDVSVWEIVMALTNGGRLVV
CCCCCCEEEECCCHHHHHHHHHHHCCCCCCEEEEEEECCEECHHHHHHHHHHCCCCEEEE
APADTLLAGDELAKVLLAHGVTHMVLPPTSYAALPTDREYPALRMLTSAGEALPPEVVHT
ECCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHH
WARPGVLFVNAYGPTEVSIISTLGHCRQDDPGAPPIGRPALNLEGYALDRHGALLPIGVP
HCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEECCC
GELHIGGVGVARGYLNREELTREKFIPHPFKPDARLYRSGDLVRWRKDGNLEYLGRIDHQ
CCEEECCCHHHHHHCCHHHHHHHHCCCCCCCCCCHHCCCCCEEEEECCCCEEEEECCCCE
VKLRGYRIELGEIEAVLASYPGVAKAVANVHSAGAQGGVKALIAYVVSTQPVDVHALREY
EEEEEEEEEHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHH
ARKKLPEFMVPAQFIHLEELPLSSSGKVDKRRLPPPRFEASASETRFVPPRTPTEQTLAS
HHHCCCHHHCCHHHEEHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
LWESLLERRPIGAEDNFFDLGGHSLLAAQVMSRVRRTFGVDVPLSAIFEQPTLTALAAVI
HHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHH
AAKEAAPQLPPLVRLTSPGDRPLSFAQERLRFLAELEGQSAAYNIPFAFTLRGSLDEAAL
HHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEECCEEEEECCCHHHHHH
RRSLQRVLERHEVLRTNFPLVDGLPVARVADAVLTLTTEDLRHAGAVSLDQRLAEESARP
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHEEEHHHHHHCCCHHHHHHHHHHCCCC
FALDVGPVVRVHLFKRADDEHVLLVAMHHIVSDGWSFGVMMREFSAFYAAEVRGEPLALP
EEEECCCHHHHHHHHCCCCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCC
DLPIQYTDYAAWQRSWLDGQAREHQLGHWRKALAGAPAVLDLPTDRPRPAVRSHRGATEP
CCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHCCCCCCC
LALAPDVAQALTSLCREQGVTAYMALLAAFGAYLGRVSGQDDVVIGSPFAGRRIAETEPL
CEECHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCH
IGFFVNSLPLRIDLGGEPTFLELLQRVRRQVLDAHEHQDVPFEKLVEVLKPERVLGTSPL
HHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHCCCCHH
FQVMLAYQQTHTAKMALPGLEVTPVAIPSGAAKFDLTLTLSETAQGFEGVLEYDRDLFDA
HHHHHHHHHHHHHHEECCCCEEEEEECCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHH
WRIQAMVRQLTGFITRLAAEPRSKVVDVDLLGAEERARLTPRAPEAAPSLPAVHEVIAAQ
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHCCCCCCCCCCCCCCHHHHHHHHHH
AAKTPTAIAVEAEDGTLTYAALEARAKAVAQALVQRGVTPGTLVALAVERSVGMMAGLLG
HCCCCCEEEEECCCCEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
ILKAGAAYVPLDPAYPRERLTFMLEDSGARVVITQAHLTSRFPGTDVVVLGDDTLESFEP
HHHCCCCEECCCCCCCCCCEEEEEECCCCEEEEEEHHHHCCCCCCCEEEECCCCHHHCCC
RSGALAYCLFTSGSTGQPKGVLIEHSALANHMAWMDDAMPLAHEDRVLQRTSLSFDASVW
CCCCEEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHH
ELFAPLMVGARLVLAPHGLGADTEHLARVLRERDVSVLQLVPSLLTALVEEPGFANLPAL
HHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHH
RRVCVGGEPLPSATVATLFSRSKAEVWNLYGPTEATIDSLAHRCLPGQVGAHGPTEPIGL
HHHHCCCCCCCHHHHHHHHHCCCHHEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCC
PIHRMEALILDGRLRPVPEGVPGELYLAGPGLARGYLNRPELTQSRFIEHAFPGGPTLRM
CHHHHHHHHCCCCCCCCCCCCCCCEEEECCCHHHCCCCCCCHHHHHHHHHCCCCCCEEEE
YKTGDVVRRLADGTFLFVGRADRQVKLRGHRIELGEVEAAIARHPAVREAVALVRGTGGD
EECHHHHHHHCCCCEEEEECCCCEEEEECCEEEHHHHHHHHHHCHHHHHHHHHHHCCCCC
SRLVAFVVPHASAQRPEPTELRSFVEQQLTANMVPGQFVLLDALPLAPNGKVDTRALSAM
CEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHH
ELADARVTALEGLPRDALELEMVRLFEEVLGVRAVGIHDSFFDLGGHSLLALKMKLAVEK
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCEEECCCCHHHHCCCCEEEHHHHHHHHHH
RLGRPLPLVSLFRNPTPAQLTAVLRTENAAVSPLVPLTPEAHALMAAGAANPNRTPVLYL
HCCCCCCHHHHHCCCCHHHHEEEEEECCCCCCCCCCCCCCHHHHHEECCCCCCCCEEEEE
VPGGGSTPFYLLSLARHLEGVAVFGLQPQGLDGDVPPHETVEAIATWYADAILAMQPEGP
ECCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHEEEECCCCC
YSVGGHSMGGHIAYELAQELKARGREVGVVAMLDTLAPFPDVTRPQGEGWDTAQWMLHLA
CCCCCCCCCCHHHHHHHHHHHHCCCCEEHEEEHHHCCCCCCCCCCCCCCCCHHHHHHHHH
GIMEAFFNVKIDLALPEVRAMGEAERLQFFVARLQAAAVLPEGAQPVHVQGILNVARAHD
HHHHHHHCEEEEEECHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHH
ALNYRPRRGQPVPLAVFRAEDRSGPSTAALDALVQDGTLGWSQLTQQACSAYPVPGTHLS
HHCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHH
LLRDPHAAVLAQHLLALIPRPTPTP
HHCCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TSEESIEDIYELAPMQHGMLFHALMEPGAGMYVEQLSCEVRGDLPINRWKEAWQHVLAR
CCHHHHHHHHHHCCHHCCHHHHHHHCCCCCCCHHHHCCEECCCCCHHHHHHHHHHHHHH
HPILRSGFLWEGLEKPLQVVAVEAEVPWRIEDIRHVPEDAQQRWIDDFLREDRLQGFDLG
CCHHHCCCHHHHHHCCEEEEEEECCCCEEHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCC
TPPLIRCALIRLDDARHLFVWTYHHLLLDGWCFSIVLREVLGAFEEGVAALPPAARPYRD
CCHHHHEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
YIAWLQEQDPSRAESFWRERLQGFKQPTPLPFTERQDTSEPAGDTQPEVTKRLSPELTAR
HHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHH
LTGFAKAHRLTLNTLVQGAWALVLARATGTDDVIFGVTVSGRPADLAGSESIVGLFINTL
HHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEEEECCCCCCCCCCCCEEEHHHHCC
PLRARLDGTAPVATFLSGLQTEQGAVEPYSYASLADIQHWSDAPKDRPLFESILVFENYP
CCEEECCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCC
LDASTLLPRSGLTISSVNTHDRISYPLALVAIPGESLELRVMYAADAFSRPMAERIARLL
CCHHHCCCCCCCEEEECCCCCCCCCCEEEEEECCCCEEEEEEEECCHHCCHHHHHHHHHH
EAALESLPGAKTVGDIDLMDEAARRVLAEWGQHPRAYDVTRPVTALLDGAAPDATAVVGP
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCEEEECC
DGQSISYRELDRRAERVARHLRQLGAGRERIVGVCIGRSVEMVVALLGVLKAGAAYLPLD
CCCCCCHHHHHHHHHHHHHHHHHHCCCHHHEEEEECCCCHHHHHHHHHHHHCCCEEECCC
PNYPAERLAYIVGDAAPVAILNTGADPIADTRVPRLDVSRVLNETATPDVPAKEPVQLDD
CCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCC
LAYVIYTSGSTGAPKGVLVTHRNLMNLVSWHTEAFGLTAKDRTTQLASTAFDASVWEIWP
EEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHH
TLAAGATLHLVPPELSSAPSDLANWLVAQQISISFLPTVVAEAVLALQWPSPCALRFVLT
HHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
GGDRLHATPPAGLPFQLVNNYGPTETTVVATSGTVAPDGKQGLPSIGRPVANARIYILDR
CCCEEECCCCCCCCHHHHCCCCCCCEEEEEECCCCCCCCCCCCCHHCCCCCCCEEEEEEC
QRRPVLPGVIGELYIGGVGVTRGYLNRPDLNVERFVPDPFAGVPEARMYASGDFARFLPD
CCCCCCCHHHHHHHCCCEEHCCCCCCCCCCCHHHCCCCCCCCCCCCCEECCCCHHHHCCC
GTIAFHGRADRQVQIRGVRVELGEIEAALAAHPDVTAAAVVSEAQRQNGDVRLIAFAVSD
CCEEECCCCCCEEEEEEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEEEHH
VVPQPDAAVLTQFLATKLPTAILPSRVIVIDRLPLTPNGKVDTAALEARALEAQPQVASA
CCCCCCHHHHHHHHHHHCCHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCHHCC
APRTPHEEILAGIWSAVLGQERVGIHDDFFDLGGHSLKATQVIARTREAFGVDIPVRAIF
CCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHH
ERRTIAQLAETLSGQGTAVEPIPHVELTGDTPVAPGQESLWFIDALGGDSAAYNVPLVLR
HHHHHHHHHHHHCCCCCEECCCCCEEECCCCCCCCCCCCEEEEEECCCCCCEECCCEEEE
LQGTLDGSALARTLQLLVERHEALRSTFHDRGGTPVLRVQAPAASVLVSEDVSPALLDAR
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHEEEECCCCHHHHHHH
IAEEVAAPFSLTDGPLFRARHFRLAPDNHVLVLNQHHIIADAWSVGVLLREFCIVYASLV
HHHHHCCCCCCCCCCCCCCEEEEECCCCEEEEEECCEEEEHHHHHHHHHHHHHHHHHHHH
SGTEPALPALPIRYADWAAWQRQRLESGRLDESVAFWREALKDAPPVLPLPTDHPRPERQ
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
RFHGKTHGFVLDAPLGQRLEALSRSSGASLFMTLLGAFAAYLGRISGQEDVVIGSPVANR
HHCCCCCCEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCC
DRHETEGVVGYFLNTLALRVDLSGDPTFSELLLRVRKTALDAYAHQDVPFEKLVAALELP
CCCHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
RGLAHNPLFQVMFVLQGQSGGELQLPDVRAEIQAPASSTSKFDLTFFVEPREGALACSIE
CCCCCCHHHHHHHHEECCCCCCEECCCHHHHHCCCCCCCCEEEEEEEEECCCCCEEEEEE
YDTDLFDADRIDRMAAHLGRLLQAIAEEPELHTSELPLLSNEERRLYADLNRTERRYTGR
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
TLPELFERQAQRTPDVVALEHQGETRTYRQLHEAAEALADRLGALGVGPGVRVSICLDRS
CHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCC
IHAQVALLAVLKAGGAYVPLDPTYPPERLRYMLEDARPRVLLTEKKYSELLPSQGLTQVL
HHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHCCCCCEEEECHHHHHHCCCCCCHHHH
LDDTEAPATKTPRPRVEPHHLAYVLYTSGSTGKPKGVAMPHRALVNLIEWQTEHASPLRT
HCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCE
LQFAPLNFDVSFQETFSTWCSGGTLVLIDEGTRRDPDALADFLDVARVQRLFLPAVALHH
EEECCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LAQAALRTEHRVPGLTEVITAGDQLRITDPIRRWFQEGGKRLHNHYGPTESHVVTALELE
HHHHHHHHHCCCCCHHHHHCCCCCEEECHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEC
GDPRHWPGLPSIGRPIANAAVHLLDANQRPVPVGVPGELYLAGTCLADGYLSRPDLTAER
CCCCCCCCCCCCCCHHHHHHEEEEECCCCCCEECCCCCEEEEEEECCCCCCCCCCCCHHH
FVELPLSPPVRAYRTGDLGRLTVDGSIEFLGRADDQVKIRGFRVEPGEIERALCAHPDVR
HEECCCCCCCHHEECCCCEEEEECCCEEEECCCCCEEEEEEEECCCHHHHHHHHCCCCCC
DAAVIVDGDATREKRLVAYVVPETVRLAELPDFLARDLPEYMVPALFVPMPELPRTPSGK
CEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCH
VARRALPAPVAPVQAESPSEPPRTPTEATVARAFEQVLGRGVVGREQDFFQLGGHSLLAM
HHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCHHHHH
QVVSRIRGDVDAAFRVSDLFENPTIASLSRVLDARRGSQTLTLARIEPAPEGAAIPLSFS
HHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEECCCC
QERLWFLDQLYPGTTAYNLPMALRLTGTLDVSAFQESLSDIVRRHPVLGMRFVERDGRVW
CHHHHHHHHHCCCCEEECCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCC
QEPRANQDVPFEQVTLGETSPEALRLLIAEEAARPFDLTNGPLFRAKLFCLDEAAHVVVA
CCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEHHHHHHHHHE
TMHHTVGDGWSISVLVRELSQLYAGRVSGQPVTLPELPVDYRDFAYQQRRHLQGEVLEQR
EHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHH
LDHWRKTLHGAPSALDLPMDRPRPPRTSMRGATERIALGKALSEAIEALSLRTGGTSFMV
HHHHHHHHCCCCCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHH
LMGGFAAYLARITGQDDIVIGTPVANRDRAELESLIGFFVGTLPLRIDLSANPTFEELVA
HHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHH
RVRASALDAYAYQDVPLEKIVEALGVERNLSHAPLFQVMLMLQNTPEGHLSLPGLALEPI
HHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCEECCCCEECCC
DLEIESAKFDLTLSFEPTREGLAGVIEYSTDLFDADRIERMVAHLQVLFADAVAHPEKRL
CEEEECCEEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHH
SELALLPEQERGVVAAFTQGRLVAPTRHVPAHRFVEEHAERTPDAIALELGQERLTYGEL
HHHHCCCCCCCCEEEEECCCEEECCCCCCCHHHHHHHHHHCCCCCEEEHHCHHHHHHHHH
NRRANRAAHQLIAMGAGPEMLVALAVPRSFEMLIGLLAIWKAGAAYVPLDLSYPKDRLDG
HHHHHHHHHHHHHCCCCHHEEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHH
ILEDSGAALMVSTHAAEQKWRAPQVRTLWLDEPADAAPTGNPDSGVRMENAAYVIYTSGS
HHCCCCCEEEEEEHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCEEEECCEEEEEECCC
TGRPKGVILEHRGLANVIEMQRHELGADAGCVMLQFSSISFDVSVWEIVMALTNGGRLVV
CCCCCCEEEECCCHHHHHHHHHHHCCCCCCEEEEEEECCEECHHHHHHHHHHCCCCEEEE
APADTLLAGDELAKVLLAHGVTHMVLPPTSYAALPTDREYPALRMLTSAGEALPPEVVHT
ECCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHH
WARPGVLFVNAYGPTEVSIISTLGHCRQDDPGAPPIGRPALNLEGYALDRHGALLPIGVP
HCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEECCC
GELHIGGVGVARGYLNREELTREKFIPHPFKPDARLYRSGDLVRWRKDGNLEYLGRIDHQ
CCEEECCCHHHHHHCCHHHHHHHHCCCCCCCCCCHHCCCCCEEEEECCCCEEEEECCCCE
VKLRGYRIELGEIEAVLASYPGVAKAVANVHSAGAQGGVKALIAYVVSTQPVDVHALREY
EEEEEEEEEHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHH
ARKKLPEFMVPAQFIHLEELPLSSSGKVDKRRLPPPRFEASASETRFVPPRTPTEQTLAS
HHHCCCHHHCCHHHEEHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
LWESLLERRPIGAEDNFFDLGGHSLLAAQVMSRVRRTFGVDVPLSAIFEQPTLTALAAVI
HHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHH
AAKEAAPQLPPLVRLTSPGDRPLSFAQERLRFLAELEGQSAAYNIPFAFTLRGSLDEAAL
HHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEECCEEEEECCCHHHHHH
RRSLQRVLERHEVLRTNFPLVDGLPVARVADAVLTLTTEDLRHAGAVSLDQRLAEESARP
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHEEEHHHHHHCCCHHHHHHHHHHCCCC
FALDVGPVVRVHLFKRADDEHVLLVAMHHIVSDGWSFGVMMREFSAFYAAEVRGEPLALP
EEEECCCHHHHHHHHCCCCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCC
DLPIQYTDYAAWQRSWLDGQAREHQLGHWRKALAGAPAVLDLPTDRPRPAVRSHRGATEP
CCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHCCCCCCC
LALAPDVAQALTSLCREQGVTAYMALLAAFGAYLGRVSGQDDVVIGSPFAGRRIAETEPL
CEECHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCH
IGFFVNSLPLRIDLGGEPTFLELLQRVRRQVLDAHEHQDVPFEKLVEVLKPERVLGTSPL
HHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHCCCCHH
FQVMLAYQQTHTAKMALPGLEVTPVAIPSGAAKFDLTLTLSETAQGFEGVLEYDRDLFDA
HHHHHHHHHHHHHHEECCCCEEEEEECCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHH
WRIQAMVRQLTGFITRLAAEPRSKVVDVDLLGAEERARLTPRAPEAAPSLPAVHEVIAAQ
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHCCCCCCCCCCCCCCHHHHHHHHHH
AAKTPTAIAVEAEDGTLTYAALEARAKAVAQALVQRGVTPGTLVALAVERSVGMMAGLLG
HCCCCCEEEEECCCCEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
ILKAGAAYVPLDPAYPRERLTFMLEDSGARVVITQAHLTSRFPGTDVVVLGDDTLESFEP
HHHCCCCEECCCCCCCCCCEEEEEECCCCEEEEEEHHHHCCCCCCCEEEECCCCHHHCCC
RSGALAYCLFTSGSTGQPKGVLIEHSALANHMAWMDDAMPLAHEDRVLQRTSLSFDASVW
CCCCEEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHH
ELFAPLMVGARLVLAPHGLGADTEHLARVLRERDVSVLQLVPSLLTALVEEPGFANLPAL
HHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHH
RRVCVGGEPLPSATVATLFSRSKAEVWNLYGPTEATIDSLAHRCLPGQVGAHGPTEPIGL
HHHHCCCCCCCHHHHHHHHHCCCHHEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCC
PIHRMEALILDGRLRPVPEGVPGELYLAGPGLARGYLNRPELTQSRFIEHAFPGGPTLRM
CHHHHHHHHCCCCCCCCCCCCCCCEEEECCCHHHCCCCCCCHHHHHHHHHCCCCCCEEEE
YKTGDVVRRLADGTFLFVGRADRQVKLRGHRIELGEVEAAIARHPAVREAVALVRGTGGD
EECHHHHHHHCCCCEEEEECCCCEEEEECCEEEHHHHHHHHHHCHHHHHHHHHHHCCCCC
SRLVAFVVPHASAQRPEPTELRSFVEQQLTANMVPGQFVLLDALPLAPNGKVDTRALSAM
CEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHH
ELADARVTALEGLPRDALELEMVRLFEEVLGVRAVGIHDSFFDLGGHSLLALKMKLAVEK
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCEEECCCCHHHHCCCCEEEHHHHHHHHHH
RLGRPLPLVSLFRNPTPAQLTAVLRTENAAVSPLVPLTPEAHALMAAGAANPNRTPVLYL
HCCCCCCHHHHHCCCCHHHHEEEEEECCCCCCCCCCCCCCHHHHHEECCCCCCCCEEEEE
VPGGGSTPFYLLSLARHLEGVAVFGLQPQGLDGDVPPHETVEAIATWYADAILAMQPEGP
ECCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHEEEECCCCC
YSVGGHSMGGHIAYELAQELKARGREVGVVAMLDTLAPFPDVTRPQGEGWDTAQWMLHLA
CCCCCCCCCCHHHHHHHHHHHHCCCCEEHEEEHHHCCCCCCCCCCCCCCCCHHHHHHHHH
GIMEAFFNVKIDLALPEVRAMGEAERLQFFVARLQAAAVLPEGAQPVHVQGILNVARAHD
HHHHHHHCEEEEEECHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHH
ALNYRPRRGQPVPLAVFRAEDRSGPSTAALDALVQDGTLGWSQLTQQACSAYPVPGTHLS
HHCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHH
LLRDPHAAVLAQHLLALIPRPTPTP
HHCCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1560782; 2477357 [H]