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The map label for this gene is lytT [H]

Identifier: 108759263

GI number: 108759263

Start: 6356064

End: 6356834

Strand: Direct

Name: lytT [H]

Synonym: MXAN_5083

Alternate gene names: 108759263

Gene position: 6356064-6356834 (Clockwise)

Preceding gene: 108760124

Following gene: 108756869

Centisome position: 69.54

GC content: 70.95

Gene sequence:

>771_bases
ATGACGCGCTTCCAGGTGCTCGTGGCCGATGACGAAGCGCCCGCGCGGGCGAAGGTGAAGCGCCTGCTGGCGGAGGACGC
CCGCTTCGCGCTGGCGGGCGAAGCGACGGACGGCCCGCAGACGCTGCGGCAGGTGGGCACCCTGCGCCCGGACCTGCTGG
TGCTCGACGTGCAGATGCCGGGCCTCACCGGCTTCGAGGTGCTGGAGGCCCTGGGCCCGGAGCATTGTCCGGCCGTCATC
TTCTCCACCGCGTACGACGCCTTCGCGCTGGCGGCCTTTGAAGCGCAGGCGGTGGACTACCTGCTGAAGCCCTACGACGC
GGAGCGCTTCGGCCGGGCGCTCGACAAGGCGCACGCGGTGCTCCGCAGCGGGATGCCGGACACCGCGCGGATCCAGTCCC
TGCTAGCGGAGCTGGGGCGGGCCCCCGCAGGCCGTCCGTTGGAGCGGCTGGTGGTGAAGGTGGGCGAGGCCTGGGTGCCC
CTGCCGCTGGCGGACGTCTGGCACCTGTCAGCCGAAGACAAGTACGTGCGGCTCTACACGGGCCAAGGCGAGCACCTGGT
ACGACAGACGCTCCGCGCCCTGGAGGAGCGGCTGGACCCCTCACGCTTCGTCCGGGTGCACCGGGGCGACATCGTCAATC
TGGACGCGGTGGCCCGCCTGGAGCCGTGGAGCCACGGGGATGGAATCCTCGTCCTCAAGGACGGGAGCTCCGTCGTACTC
AGCCGCACCTGGCGTGAAGCGTTCCTCCAGAAGTGGGGACTGGAGGGGTAA

Upstream 100 bases:

>100_bases
TCCTGACGCTGCTCCACGGGGGCCGAGCGCGGCTGGAGCGGAGCCACGGCCCCGAGGGCGGCGCGCGCGTGTCGCTGTGG
CTGCCCCGGGAGACCGCGGC

Downstream 100 bases:

>100_bases
GCGTCACTGCTACAGGGCTGTGGCAGCAAATTTGGTTGTGTCAGCCCTGCCTGTAGAGTGGGCGGGCTGCCATGGAGAAC
GTCCACGAGTTCAGAGAGGG

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MTRFQVLVADDEAPARAKVKRLLAEDARFALAGEATDGPQTLRQVGTLRPDLLVLDVQMPGLTGFEVLEALGPEHCPAVI
FSTAYDAFALAAFEAQAVDYLLKPYDAERFGRALDKAHAVLRSGMPDTARIQSLLAELGRAPAGRPLERLVVKVGEAWVP
LPLADVWHLSAEDKYVRLYTGQGEHLVRQTLRALEERLDPSRFVRVHRGDIVNLDAVARLEPWSHGDGILVLKDGSSVVL
SRTWREAFLQKWGLEG

Sequences:

>Translated_256_residues
MTRFQVLVADDEAPARAKVKRLLAEDARFALAGEATDGPQTLRQVGTLRPDLLVLDVQMPGLTGFEVLEALGPEHCPAVI
FSTAYDAFALAAFEAQAVDYLLKPYDAERFGRALDKAHAVLRSGMPDTARIQSLLAELGRAPAGRPLERLVVKVGEAWVP
LPLADVWHLSAEDKYVRLYTGQGEHLVRQTLRALEERLDPSRFVRVHRGDIVNLDAVARLEPWSHGDGILVLKDGSSVVL
SRTWREAFLQKWGLEG
>Mature_255_residues
TRFQVLVADDEAPARAKVKRLLAEDARFALAGEATDGPQTLRQVGTLRPDLLVLDVQMPGLTGFEVLEALGPEHCPAVIF
STAYDAFALAAFEAQAVDYLLKPYDAERFGRALDKAHAVLRSGMPDTARIQSLLAELGRAPAGRPLERLVVKVGEAWVPL
PLADVWHLSAEDKYVRLYTGQGEHLVRQTLRALEERLDPSRFVRVHRGDIVNLDAVARLEPWSHGDGILVLKDGSSVVLS
RTWREAFLQKWGLEG

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082052, Length=253, Percent_Identity=33.9920948616601, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1788724, Length=248, Percent_Identity=28.2258064516129, Blast_Score=111, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 28293; Mature: 28162

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRFQVLVADDEAPARAKVKRLLAEDARFALAGEATDGPQTLRQVGTLRPDLLVLDVQMP
CCEEEEEEECCCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHCCCCCEEEEEEECC
GLTGFEVLEALGPEHCPAVIFSTAYDAFALAAFEAQAVDYLLKPYDAERFGRALDKAHAV
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LRSGMPDTARIQSLLAELGRAPAGRPLERLVVKVGEAWVPLPLADVWHLSAEDKYVRLYT
HHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCHHHHHCCCCCCCEEEEEE
GQGEHLVRQTLRALEERLDPSRFVRVHRGDIVNLDAVARLEPWSHGDGILVLKDGSSVVL
CCCHHHHHHHHHHHHHHCCHHHEEEECCCCEECCCHHHEECCCCCCCCEEEEECCCCEEH
SRTWREAFLQKWGLEG
HHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TRFQVLVADDEAPARAKVKRLLAEDARFALAGEATDGPQTLRQVGTLRPDLLVLDVQMP
CEEEEEEECCCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHCCCCCEEEEEEECC
GLTGFEVLEALGPEHCPAVIFSTAYDAFALAAFEAQAVDYLLKPYDAERFGRALDKAHAV
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LRSGMPDTARIQSLLAELGRAPAGRPLERLVVKVGEAWVPLPLADVWHLSAEDKYVRLYT
HHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCHHHHHCCCCCCCEEEEEE
GQGEHLVRQTLRALEERLDPSRFVRVHRGDIVNLDAVARLEPWSHGDGILVLKDGSSVVL
CCCHHHHHHHHHHHHHHCCHHHEEEECCCCEECCCHHHEECCCCCCCCEEEEECCCCEEH
SRTWREAFLQKWGLEG
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]