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The map label for this gene is comEB [H]

Identifier: 108759248

GI number: 108759248

Start: 4953949

End: 4954401

Strand: Reverse

Name: comEB [H]

Synonym: MXAN_4044

Alternate gene names: 108759248

Gene position: 4954401-4953949 (Counterclockwise)

Preceding gene: 108758456

Following gene: 108760882

Centisome position: 54.21

GC content: 67.77

Gene sequence:

>453_bases
ATGGCCGGACGTGTCTCGTGGGATCAGTACTTCATGGACATCGCGACGCAGGTGGCCTCGCGCGCCACGTGTGATCGCAA
GCACGTGGGCGCCGTCATCGTCCGGGGCAGGACCATCCTGTCCACCGGCTACAACGGCGCCATCCGCGGGCTGCCGCACT
GCGATGACGTGGGCCACATGATGGAGAACGGACACTGCGTGGCCACCGTCCACGCGGAGGCCAACGCCATCATCCAGGCC
GCCACCAACGGCGTCAGCATCGACGGGGCGACCATCTACACCACCGCCTCGCCTTGCTGGCCGTGCTTCAAGCTGATCGC
CAACGCGGGCCTGGTGCGCATCGTGTTCGGCGAGTTCTACCGGGACCCTCGCATCTTCGAGTACGCGGCCCGGCTGAAGC
TGGACCTGGTGGGTCTGGGCGATGCCGCCCGGCCTCCCGCCTCGGGTGTCTGA

Upstream 100 bases:

>100_bases
TTAGCGACTTCGCGCGGTGTCCCAGGTCCGCCTTGGCCGGCTGGCAGGAATCTCGACACCGCGCGCGAGCGGGGTACATC
CGCCGGACTGGAGGCGTGGG

Downstream 100 bases:

>100_bases
GCGCCCCGCACCGCGGGGCAGTACGGGCATTTCCGCGCGGATCTCGCGCGCTCCTCAATCGTCACCTGAGAAACACTCGC
GGGCGGACGTAAGTCCGCGC

Product: cytidine and deoxycytidylate deaminase zinc-binding domain-containing protein

Products: dUMP; NH3

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MAGRVSWDQYFMDIATQVASRATCDRKHVGAVIVRGRTILSTGYNGAIRGLPHCDDVGHMMENGHCVATVHAEANAIIQA
ATNGVSIDGATIYTTASPCWPCFKLIANAGLVRIVFGEFYRDPRIFEYAARLKLDLVGLGDAARPPASGV

Sequences:

>Translated_150_residues
MAGRVSWDQYFMDIATQVASRATCDRKHVGAVIVRGRTILSTGYNGAIRGLPHCDDVGHMMENGHCVATVHAEANAIIQA
ATNGVSIDGATIYTTASPCWPCFKLIANAGLVRIVFGEFYRDPRIFEYAARLKLDLVGLGDAARPPASGV
>Mature_149_residues
AGRVSWDQYFMDIATQVASRATCDRKHVGAVIVRGRTILSTGYNGAIRGLPHCDDVGHMMENGHCVATVHAEANAIIQAA
TNGVSIDGATIYTTASPCWPCFKLIANAGLVRIVFGEFYRDPRIFEYAARLKLDLVGLGDAARPPASGV

Specific function: Dispensable for transformability [H]

COG id: COG2131

COG function: function code F; Deoxycytidylate deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6321938, Length=126, Percent_Identity=38.8888888888889, Blast_Score=89, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24667298, Length=146, Percent_Identity=34.2465753424658, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24667302, Length=146, Percent_Identity=34.2465753424658, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR013404
- InterPro:   IPR015517
- InterPro:   IPR016193
- InterPro:   IPR016473 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.12

Molecular weight: Translated: 16081; Mature: 15949

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGRVSWDQYFMDIATQVASRATCDRKHVGAVIVRGRTILSTGYNGAIRGLPHCDDVGHM
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECEEEEECCCCCCCCCCCCCCHHHHH
MENGHCVATVHAEANAIIQAATNGVSIDGATIYTTASPCWPCFKLIANAGLVRIVFGEFY
HCCCCEEEEEECCCCEEEEECCCCEEECCEEEEEECCCHHHHHHHHHCCCEEEEEEHHHC
RDPRIFEYAARLKLDLVGLGDAARPPASGV
CCCHHHHHHHHHEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
AGRVSWDQYFMDIATQVASRATCDRKHVGAVIVRGRTILSTGYNGAIRGLPHCDDVGHM
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECEEEEECCCCCCCCCCCCCCHHHHH
MENGHCVATVHAEANAIIQAATNGVSIDGATIYTTASPCWPCFKLIANAGLVRIVFGEFY
HCCCCEEEEEECCCCEEEEECCCCEEECCEEEEEECCCHHHHHHHHHCCCEEEEEEHHHC
RDPRIFEYAARLKLDLVGLGDAARPPASGV
CCCHHHHHHHHHEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dCMP; H2O

Specific reaction: dCMP + H2O = dUMP + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7968523; 8969508; 9384377 [H]