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The map label for this gene is 108758973

Identifier: 108758973

GI number: 108758973

Start: 2022815

End: 2024137

Strand: Reverse

Name: 108758973

Synonym: MXAN_1706

Alternate gene names: NA

Gene position: 2024137-2022815 (Counterclockwise)

Preceding gene: 108760461

Following gene: 108761554

Centisome position: 22.15

GC content: 64.25

Gene sequence:

>1323_bases
GTGGCCATGAAGCCCCTGCGTCGCTCAACAGTCCTTGGATTGCTGGTGCTCAGCGTCCATCTCGCTGCGTGCCTCGACGT
CGACGAGGCGGTGGACCAATTCTGCAACAGTAAACCTGGCGCATGCCTGGATGGCGCCTCGGATGCGGGCCCTGATGGCA
ATGGCAGCCTGGATGGAGGTAACGATGGAGGTGGGCCGCACGGCGAGGACGGCGGGCCGCACGGCGGAGGGGACGGCGGT
TCGGACGCAGGCACTGACGGGGGACCTCCGGATGGCGGGCGAGAACCGCCGGGGTGGAAGTCGGTGGCACCGATGCAGAC
GCGGCGCACAGGGCATACGGCCACGGAACTGAGAAATGGTCGAGTGCTCGTCGTTGGTGGGAGTAGCTCAGGCAACACCC
CCACGAACACCACGGAGCTCTACACCGTCTCATCAAACAGTTGGAGTCCTGGGCCAGACCTCGCGACGGCGCGCATGGAC
CACACCGCCACCCTTTTACCGAATGGAAACGTATTGGTGGTCGGTGGCCGGGGCCCCGGAGGTGGCGCGCTGAACAGTGC
CGAAATCTACGATGCGGAAGCGAATGAGTGGGCTCCTGCCAATCCCATCCCACTCGGAGCACGCGCCAGCCATGCCGCCG
TCCTGCTTCCCTCGGGGAAGGTGCTGGTGGCGGGTGGCGGGAACTCGCATCTCGACGGGCTGAACACCGCCGCGCTCTAT
CACCCGGACACCGACTCCTGGACAGATGCTGGGAGCTTGAATGTCAAACGCAACGTACTGACACTCACCCTCCTGGAAGC
GGGCGTGGTGGTGGCCATTGGTGGCTTCAATGCTGCTGGAGCGGAGACGACGGCCGAGGTCTACGACTCGAATCAACCAG
AGGCGGGATGGCGACTCCTCCTGGCACAGATGGAACATGGGCGCCACGGGCACGCCTCCACGCGGCTGCCTTCTGGAAGA
ATCCTGGTGACCGGCTCCCTCGAGGGCTCACCAGGACGGGTCCTCAGGGCAGCGGAACTCTTTCAATTGAGCAGCACTTC
GTGGACGCCCCAGGCGGAAATGATGGAAGCCCGCTTCTTTCACACGGCGACCGCATTGCCCTCAGGCGAGGTGCTGATTG
CGGGCGGGTATTCCAGCCCCTACGCAATGCCACGTGCCTCCGCGGAGATATTCCGGCGAGATGGCTCTTCGGAGTTCATC
GCTCCCATGTCATCGGCGCGCGTCAATCACACGGCCACATGGCTGGAATCAGGGAGTGTGCTCATCATCGGGGGTATCGA
CGGCGGTGCCGTACTGAACACCGCCGAGCGGTATGTCCCCTGA

Upstream 100 bases:

>100_bases
GGCTGGGCGCCGCCACGGGAATGTACCTGCTGGGGTCGCCAGAGAAGCAAGGCTCCCTACAATTCGGGCTGGATGGGACG
TCCGCGTTCGTGTCTGGAAG

Downstream 100 bases:

>100_bases
CGCCTGTGCCTGTCTCGTATTCGGTCGCTGCGTAGTGAGCTTCAAAGAACTCGCTTCCCCGGAGTCATCCCATGGCCAAA
ATCACAGCCCCCAAGCCGCA

Product: kelch domain-containing protein

Products: NA

Alternate protein names: Kelch Domain-Containing Protein; Kelch Domain Protein; Kelch Repeat Type 1-Containing Protein; NHL Repeat Containing Protein; Transposase; Kelch Motif-Containing Protein; Ig Domain-Containing Domain-Containing Protein; Ig Domain Domain Protein; Kelch Related Protein; Secreted Protein

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MAMKPLRRSTVLGLLVLSVHLAACLDVDEAVDQFCNSKPGACLDGASDAGPDGNGSLDGGNDGGGPHGEDGGPHGGGDGG
SDAGTDGGPPDGGREPPGWKSVAPMQTRRTGHTATELRNGRVLVVGGSSSGNTPTNTTELYTVSSNSWSPGPDLATARMD
HTATLLPNGNVLVVGGRGPGGGALNSAEIYDAEANEWAPANPIPLGARASHAAVLLPSGKVLVAGGGNSHLDGLNTAALY
HPDTDSWTDAGSLNVKRNVLTLTLLEAGVVVAIGGFNAAGAETTAEVYDSNQPEAGWRLLLAQMEHGRHGHASTRLPSGR
ILVTGSLEGSPGRVLRAAELFQLSSTSWTPQAEMMEARFFHTATALPSGEVLIAGGYSSPYAMPRASAEIFRRDGSSEFI
APMSSARVNHTATWLESGSVLIIGGIDGGAVLNTAERYVP

Sequences:

>Translated_440_residues
MAMKPLRRSTVLGLLVLSVHLAACLDVDEAVDQFCNSKPGACLDGASDAGPDGNGSLDGGNDGGGPHGEDGGPHGGGDGG
SDAGTDGGPPDGGREPPGWKSVAPMQTRRTGHTATELRNGRVLVVGGSSSGNTPTNTTELYTVSSNSWSPGPDLATARMD
HTATLLPNGNVLVVGGRGPGGGALNSAEIYDAEANEWAPANPIPLGARASHAAVLLPSGKVLVAGGGNSHLDGLNTAALY
HPDTDSWTDAGSLNVKRNVLTLTLLEAGVVVAIGGFNAAGAETTAEVYDSNQPEAGWRLLLAQMEHGRHGHASTRLPSGR
ILVTGSLEGSPGRVLRAAELFQLSSTSWTPQAEMMEARFFHTATALPSGEVLIAGGYSSPYAMPRASAEIFRRDGSSEFI
APMSSARVNHTATWLESGSVLIIGGIDGGAVLNTAERYVP
>Mature_439_residues
AMKPLRRSTVLGLLVLSVHLAACLDVDEAVDQFCNSKPGACLDGASDAGPDGNGSLDGGNDGGGPHGEDGGPHGGGDGGS
DAGTDGGPPDGGREPPGWKSVAPMQTRRTGHTATELRNGRVLVVGGSSSGNTPTNTTELYTVSSNSWSPGPDLATARMDH
TATLLPNGNVLVVGGRGPGGGALNSAEIYDAEANEWAPANPIPLGARASHAAVLLPSGKVLVAGGGNSHLDGLNTAALYH
PDTDSWTDAGSLNVKRNVLTLTLLEAGVVVAIGGFNAAGAETTAEVYDSNQPEAGWRLLLAQMEHGRHGHASTRLPSGRI
LVTGSLEGSPGRVLRAAELFQLSSTSWTPQAEMMEARFFHTATALPSGEVLIAGGYSSPYAMPRASAEIFRRDGSSEFIA
PMSSARVNHTATWLESGSVLIIGGIDGGAVLNTAERYVP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI24475847, Length=259, Percent_Identity=28.5714285714286, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI55925604, Length=273, Percent_Identity=28.9377289377289, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI166235129, Length=271, Percent_Identity=26.5682656826568, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI11056006, Length=217, Percent_Identity=31.7972350230415, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI148664209, Length=197, Percent_Identity=27.9187817258883, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI55770880, Length=277, Percent_Identity=29.2418772563177, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI65289632, Length=277, Percent_Identity=29.6028880866426, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI65289292, Length=277, Percent_Identity=29.2418772563177, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI284413752, Length=278, Percent_Identity=29.8561151079137, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI239835724, Length=271, Percent_Identity=26.1992619926199, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI239835720, Length=271, Percent_Identity=26.1992619926199, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI40807500, Length=162, Percent_Identity=32.0987654320988, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI239835722, Length=271, Percent_Identity=26.1992619926199, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI194097389, Length=279, Percent_Identity=23.6559139784946, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI55741643, Length=239, Percent_Identity=28.4518828451883, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI8922640, Length=343, Percent_Identity=24.4897959183673, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI14780904, Length=277, Percent_Identity=27.7978339350181, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI34101268, Length=285, Percent_Identity=29.1228070175439, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI44680141, Length=191, Percent_Identity=31.9371727748691, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI38194229, Length=268, Percent_Identity=28.7313432835821, Blast_Score=65, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI71990958, Length=300, Percent_Identity=26, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17532459, Length=267, Percent_Identity=26.2172284644195, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508613, Length=190, Percent_Identity=32.1052631578947, Blast_Score=68, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17553490, Length=323, Percent_Identity=24.1486068111455, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115534570, Length=276, Percent_Identity=28.6231884057971, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI45549017, Length=272, Percent_Identity=27.9411764705882, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI160715163, Length=191, Percent_Identity=32.4607329842932, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI160714879, Length=191, Percent_Identity=32.4607329842932, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI160714877, Length=191, Percent_Identity=32.4607329842932, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24584926, Length=272, Percent_Identity=27.9411764705882, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24646172, Length=277, Percent_Identity=25.9927797833935, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21356823, Length=277, Percent_Identity=25.9927797833935, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24664829, Length=162, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28573706, Length=270, Percent_Identity=30, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI19922570, Length=270, Percent_Identity=30, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 44903; Mature: 44772

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMKPLRRSTVLGLLVLSVHLAACLDVDEAVDQFCNSKPGACLDGASDAGPDGNGSLDGG
CCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCC
NDGGGPHGEDGGPHGGGDGGSDAGTDGGPPDGGREPPGWKSVAPMQTRRTGHTATELRNG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCHHHHHCCC
RVLVVGGSSSGNTPTNTTELYTVSSNSWSPGPDLATARMDHTATLLPNGNVLVVGGRGPG
EEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCEEEECCCEEEEECCCCEEEEECCCCC
GGALNSAEIYDAEANEWAPANPIPLGARASHAAVLLPSGKVLVAGGGNSHLDGLNTAALY
CCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEECCCCCCCCCCCEEEEE
HPDTDSWTDAGSLNVKRNVLTLTLLEAGVVVAIGGFNAAGAETTAEVYDSNQPEAGWRLL
CCCCCCCCCCCCCEEECCEEEEEEECCCEEEEEECCCCCCCCCCHHHHCCCCCCHHHHHH
LAQMEHGRHGHASTRLPSGRILVTGSLEGSPGRVLRAAELFQLSSTSWTPQAEMMEARFF
HHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEHHHHHEECCCCCCCHHHHHHHHHH
HTATALPSGEVLIAGGYSSPYAMPRASAEIFRRDGSSEFIAPMSSARVNHTATWLESGSV
HHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHCCCCCCEECCHHHCCCCCEEEEECCCCE
LIIGGIDGGAVLNTAERYVP
EEEECCCCCHHCCCHHHCCC
>Mature Secondary Structure 
AMKPLRRSTVLGLLVLSVHLAACLDVDEAVDQFCNSKPGACLDGASDAGPDGNGSLDGG
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCC
NDGGGPHGEDGGPHGGGDGGSDAGTDGGPPDGGREPPGWKSVAPMQTRRTGHTATELRNG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCHHHHHCCC
RVLVVGGSSSGNTPTNTTELYTVSSNSWSPGPDLATARMDHTATLLPNGNVLVVGGRGPG
EEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCEEEECCCEEEEECCCCEEEEECCCCC
GGALNSAEIYDAEANEWAPANPIPLGARASHAAVLLPSGKVLVAGGGNSHLDGLNTAALY
CCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEECCCCCCCCCCCEEEEE
HPDTDSWTDAGSLNVKRNVLTLTLLEAGVVVAIGGFNAAGAETTAEVYDSNQPEAGWRLL
CCCCCCCCCCCCCEEECCEEEEEEECCCEEEEEECCCCCCCCCCHHHHCCCCCCHHHHHH
LAQMEHGRHGHASTRLPSGRILVTGSLEGSPGRVLRAAELFQLSSTSWTPQAEMMEARFF
HHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEHHHHHEECCCCCCCHHHHHHHHHH
HTATALPSGEVLIAGGYSSPYAMPRASAEIFRRDGSSEFIAPMSSARVNHTATWLESGSV
HHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHCCCCCCEECCHHHCCCCCEEEEECCCCE
LIIGGIDGGAVLNTAERYVP
EEEECCCCCHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA