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The map label for this gene is kstR2 [H]

Identifier: 108758930

GI number: 108758930

Start: 5226785

End: 5227471

Strand: Direct

Name: kstR2 [H]

Synonym: MXAN_4263

Alternate gene names: 108758930

Gene position: 5226785-5227471 (Clockwise)

Preceding gene: 108763958

Following gene: 108759267

Centisome position: 57.19

GC content: 65.94

Gene sequence:

>687_bases
GTGACGAACACCGGAGGACGGAAGCCGGACGAGGGCGAGCGCTACCGAGCCATCCTTGAAACGGCGGCGCGGCTCATCTG
TGACCGGGGGTACGAGGGCACGTCGATGCAGGAGATCGCCGCCGCGTGCCGGATGACGAAGGCGGGCCTCTACCACCACA
TCCAGAACAAGGAGCAGTTGCTCTTCGCCATCATGAACTACGGGATGGACCTGTTCGAGGAGCAGGTCCTCTCGCGGGTG
CAGGACATCGCGAATCCGGTGGAGCGGCTTCGCGCGTGCATGCGCCACAACATCCTGCTGGTGACGCGGGGGTGGAGCAA
GGAGGTCATCATCATCCTCCACGAGCACGCCACGCTCACCGGCGAGACGCGCGCCTTCATCGACGCCCGGAAGAAGAAGT
ACGTGGACTTCCTGGAGGAGGCCTTTTCGCAGGCCTCGCAGCAGGGCCTCATCCGCCCCGTGGACCCGACGGTGGGCGCC
TTCTCGTTCCTGGGAATGGTGCTGTGGATCTACAAGTGGTTCAAGCCGGACGGGCGCCTCACGGATGAGCAGATCGCCGA
CGGCATGGTGGGCATGTTGTTCCCGCCCTTCGCCGCCGCTGGGGACACCGCTGGACAGGCAGGGCCCTCCCCGTTGCGCA
TGGTGCCGAGCGTGTCGGCCACCGGCACGGATTCGGAGGACGCATGA

Upstream 100 bases:

>100_bases
AATCAGGAGGCTCGCCGGCCCGGGGGCCGACTTTGGCGATTGACACTCCGCGTCGGGCGCTGCTACCTACCGGTCGGTAG
GTCTCCAGAAGGGAGCAGAC

Downstream 100 bases:

>100_bases
AGACGGCGCGCTGGTGCTCGCTGGAGGAGGCGGTGGCTTCCATTCCGGATGGCGCGTCGCTGGCCACCGGCGGTTTCATG
CTGGGTCGCGCCCCCATGGC

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MTNTGGRKPDEGERYRAILETAARLICDRGYEGTSMQEIAAACRMTKAGLYHHIQNKEQLLFAIMNYGMDLFEEQVLSRV
QDIANPVERLRACMRHNILLVTRGWSKEVIIILHEHATLTGETRAFIDARKKKYVDFLEEAFSQASQQGLIRPVDPTVGA
FSFLGMVLWIYKWFKPDGRLTDEQIADGMVGMLFPPFAAAGDTAGQAGPSPLRMVPSVSATGTDSEDA

Sequences:

>Translated_228_residues
MTNTGGRKPDEGERYRAILETAARLICDRGYEGTSMQEIAAACRMTKAGLYHHIQNKEQLLFAIMNYGMDLFEEQVLSRV
QDIANPVERLRACMRHNILLVTRGWSKEVIIILHEHATLTGETRAFIDARKKKYVDFLEEAFSQASQQGLIRPVDPTVGA
FSFLGMVLWIYKWFKPDGRLTDEQIADGMVGMLFPPFAAAGDTAGQAGPSPLRMVPSVSATGTDSEDA
>Mature_227_residues
TNTGGRKPDEGERYRAILETAARLICDRGYEGTSMQEIAAACRMTKAGLYHHIQNKEQLLFAIMNYGMDLFEEQVLSRVQ
DIANPVERLRACMRHNILLVTRGWSKEVIIILHEHATLTGETRAFIDARKKKYVDFLEEAFSQASQQGLIRPVDPTVGAF
SFLGMVLWIYKWFKPDGRLTDEQIADGMVGMLFPPFAAAGDTAGQAGPSPLRMVPSVSATGTDSEDA

Specific function: Controls the expression of a small regulon that may play a role in the utilization of cholesterol [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 25372; Mature: 25241

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNTGGRKPDEGERYRAILETAARLICDRGYEGTSMQEIAAACRMTKAGLYHHIQNKEQL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHH
LFAIMNYGMDLFEEQVLSRVQDIANPVERLRACMRHNILLVTRGWSKEVIIILHEHATLT
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCEEEEEECCCCCC
GETRAFIDARKKKYVDFLEEAFSQASQQGLIRPVDPTVGAFSFLGMVLWIYKWFKPDGRL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
TDEQIADGMVGMLFPPFAAAGDTAGQAGPSPLRMVPSVSATGTDSEDA
CHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCC
>Mature Secondary Structure 
TNTGGRKPDEGERYRAILETAARLICDRGYEGTSMQEIAAACRMTKAGLYHHIQNKEQL
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHH
LFAIMNYGMDLFEEQVLSRVQDIANPVERLRACMRHNILLVTRGWSKEVIIILHEHATLT
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCEEEEEECCCCCC
GETRAFIDARKKKYVDFLEEAFSQASQQGLIRPVDPTVGAFSFLGMVLWIYKWFKPDGRL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
TDEQIADGMVGMLFPPFAAAGDTAGQAGPSPLRMVPSVSATGTDSEDA
CHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]