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The map label for this gene is clpX [H]

Identifier: 108758848

GI number: 108758848

Start: 619994

End: 621154

Strand: Reverse

Name: clpX [H]

Synonym: MXAN_0540

Alternate gene names: 108758848

Gene position: 621154-619994 (Counterclockwise)

Preceding gene: 108758149

Following gene: 108759639

Centisome position: 6.8

GC content: 70.37

Gene sequence:

>1161_bases
TTGGAGTCCCCTGGAATGAGCATCACCCACCCTGGCCTGGAGCCGCTGCCCGAATCGCCTGACGAGGACGTGCGCGCGCG
CGTCGCCGCCATCGAGGTCCTCTCTCCCCGCGAAATCGACGAGCGGTTGTCGGACCTCGGCTACCGGGGGCAGACGGAGG
CGCGCCGCGCGGCATCCGTGCTGGCGTACCGGCACCTGCGCCGCATCCGTCACCTGTTCCTGGAGGGGCTCGCCCCCGAA
CCGGGCATGCGGGAGAACTGCCTCTTCCTGGGGCCCACCGGCTCAGGGAAGACGTTCCTCGTGGAGCTGCTGTTCCGCGA
AATCCTCGCCGTTCCCACCGTGCTGGCGGACGCCACGCAGTTCTCCGAAACGGGCTACGTGGGCGACGACGTGAGCACGC
TGCTGTCGCGCCTGTACGAAGCCGCGGACCGGAACGCGGCCTGGGCCGGCTGCGGCGTGGTGTGCATGGACGAGTTCGAC
AAGCTCGCCACCAGCCGCTCCGACAGCCGCTTCGCCGGCCAGCAGACCACGAAGGACGTCAGCGGCTTCGGCGTGCAGCG
CAGCCTGCTGCACATGCTGTCCGCCCCCAGCGCGGACTTCCCGCCCGACTTCGGCTTCACCAGCCGCCAGCGGCCCGACA
CCATGGAGCTGGCCTGCGTCACCTTCATCGCGTGCGGCGCCTTCAGTGGCCTGAGCGCCACCGCGGAGGGGCTGGCCCGG
AGCGAACACCTGGGCTTCGGCCGCGAACCGCTCCCGGCGCGGGTGGAGAGCATCGCCACGCGAGTGACGGAGGAGCAGTT
GGAACAGACCACCGCCTTCGCGCGCTACGGCTTCATCCCGGAGCTCATTGGCCGCTTCAACCGGCTGGTCTCCTTTTCGC
CCCTGGACGCGGGCACCCTGGACGACATCCTTCAACACAACGTGCTGCGTGCCTACGAGCGCGAGTTCGAGCAGGAAGGG
CTGCGCCTGCAGGTGGACACCGAGGTGCGGGAGTTCGTGGTGGCCCGCGCGCTCAAGCGGGAGACGGGCGCACGAGGGCT
GCGCACCACGCTCGCCCCCTTGCTGGAGCGGGCCGCCTACGAGCACTTTGGCCACCGAGACAACGACGGCACGCTCCGGC
TGACGCTGGAGGCCGGCGAGGTCCAGGCGCGGCGGGTGTAG

Upstream 100 bases:

>100_bases
ACCCCGGGTTGGAAGACGGCCGTGAGCAGGCGCGCGACCCGCCTTGTCGGCCCCGCGCCCCGCCAGGATGATGCGCCCGC
CGGCGGCCACCCGCCCCTGA

Downstream 100 bases:

>100_bases
CCGCGCGCCTCCCTGCCAGGTGACGTGCCAGGGAAGCAGGCCCGTTCCACACCCCGCACGCACAAGCCTTACGGTTTTGC
TGAGCAACGGAATCCGGAGG

Product: ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MESPGMSITHPGLEPLPESPDEDVRARVAAIEVLSPREIDERLSDLGYRGQTEARRAASVLAYRHLRRIRHLFLEGLAPE
PGMRENCLFLGPTGSGKTFLVELLFREILAVPTVLADATQFSETGYVGDDVSTLLSRLYEAADRNAAWAGCGVVCMDEFD
KLATSRSDSRFAGQQTTKDVSGFGVQRSLLHMLSAPSADFPPDFGFTSRQRPDTMELACVTFIACGAFSGLSATAEGLAR
SEHLGFGREPLPARVESIATRVTEEQLEQTTAFARYGFIPELIGRFNRLVSFSPLDAGTLDDILQHNVLRAYEREFEQEG
LRLQVDTEVREFVVARALKRETGARGLRTTLAPLLERAAYEHFGHRDNDGTLRLTLEAGEVQARRV

Sequences:

>Translated_386_residues
MESPGMSITHPGLEPLPESPDEDVRARVAAIEVLSPREIDERLSDLGYRGQTEARRAASVLAYRHLRRIRHLFLEGLAPE
PGMRENCLFLGPTGSGKTFLVELLFREILAVPTVLADATQFSETGYVGDDVSTLLSRLYEAADRNAAWAGCGVVCMDEFD
KLATSRSDSRFAGQQTTKDVSGFGVQRSLLHMLSAPSADFPPDFGFTSRQRPDTMELACVTFIACGAFSGLSATAEGLAR
SEHLGFGREPLPARVESIATRVTEEQLEQTTAFARYGFIPELIGRFNRLVSFSPLDAGTLDDILQHNVLRAYEREFEQEG
LRLQVDTEVREFVVARALKRETGARGLRTTLAPLLERAAYEHFGHRDNDGTLRLTLEAGEVQARRV
>Mature_386_residues
MESPGMSITHPGLEPLPESPDEDVRARVAAIEVLSPREIDERLSDLGYRGQTEARRAASVLAYRHLRRIRHLFLEGLAPE
PGMRENCLFLGPTGSGKTFLVELLFREILAVPTVLADATQFSETGYVGDDVSTLLSRLYEAADRNAAWAGCGVVCMDEFD
KLATSRSDSRFAGQQTTKDVSGFGVQRSLLHMLSAPSADFPPDFGFTSRQRPDTMELACVTFIACGAFSGLSATAEGLAR
SEHLGFGREPLPARVESIATRVTEEQLEQTTAFARYGFIPELIGRFNRLVSFSPLDAGTLDDILQHNVLRAYEREFEQEG
LRLQVDTEVREFVVARALKRETGARGLRTTLAPLLERAAYEHFGHRDNDGTLRLTLEAGEVQARRV

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=300, Percent_Identity=31, Blast_Score=134, Evalue=1e-31,
Organism=Escherichia coli, GI1786642, Length=338, Percent_Identity=33.7278106508876, Blast_Score=160, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI71982908, Length=285, Percent_Identity=34.7368421052632, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71982905, Length=285, Percent_Identity=34.7368421052632, Blast_Score=138, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI71988663, Length=393, Percent_Identity=28.2442748091603, Blast_Score=137, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI71988660, Length=245, Percent_Identity=29.7959183673469, Blast_Score=99, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6319704, Length=316, Percent_Identity=31.9620253164557, Blast_Score=128, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24648289, Length=292, Percent_Identity=29.1095890410959, Blast_Score=124, Evalue=8e-29,
Organism=Drosophila melanogaster, GI24648291, Length=292, Percent_Identity=29.1095890410959, Blast_Score=124, Evalue=8e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 42663; Mature: 42663

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00041 HTH_ARAC_FAMILY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESPGMSITHPGLEPLPESPDEDVRARVAAIEVLSPREIDERLSDLGYRGQTEARRAASV
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHH
LAYRHLRRIRHLFLEGLAPEPGMRENCLFLGPTGSGKTFLVELLFREILAVPTVLADATQ
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FSETGYVGDDVSTLLSRLYEAADRNAAWAGCGVVCMDEFDKLATSRSDSRFAGQQTTKDV
HHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCHHCCCHHHHHH
SGFGVQRSLLHMLSAPSADFPPDFGFTSRQRPDTMELACVTFIACGAFSGLSATAEGLAR
HHCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
SEHLGFGREPLPARVESIATRVTEEQLEQTTAFARYGFIPELIGRFNRLVSFSPLDAGTL
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHH
DDILQHNVLRAYEREFEQEGLRLQVDTEVREFVVARALKRETGARGLRTTLAPLLERAAY
HHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
EHFGHRDNDGTLRLTLEAGEVQARRV
HHCCCCCCCCEEEEEEECCCCCCCCC
>Mature Secondary Structure
MESPGMSITHPGLEPLPESPDEDVRARVAAIEVLSPREIDERLSDLGYRGQTEARRAASV
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHH
LAYRHLRRIRHLFLEGLAPEPGMRENCLFLGPTGSGKTFLVELLFREILAVPTVLADATQ
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FSETGYVGDDVSTLLSRLYEAADRNAAWAGCGVVCMDEFDKLATSRSDSRFAGQQTTKDV
HHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCHHCCCHHHHHH
SGFGVQRSLLHMLSAPSADFPPDFGFTSRQRPDTMELACVTFIACGAFSGLSATAEGLAR
HHCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
SEHLGFGREPLPARVESIATRVTEEQLEQTTAFARYGFIPELIGRFNRLVSFSPLDAGTL
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHH
DDILQHNVLRAYEREFEQEGLRLQVDTEVREFVVARALKRETGARGLRTTLAPLLERAAY
HHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
EHFGHRDNDGTLRLTLEAGEVQARRV
HHCCCCCCCCEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA