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The map label for this gene is rfbE [H]

Identifier: 108758844

GI number: 108758844

Start: 1942204

End: 1943304

Strand: Direct

Name: rfbE [H]

Synonym: MXAN_1639

Alternate gene names: 108758844

Gene position: 1942204-1943304 (Clockwise)

Preceding gene: 108760027

Following gene: 108762038

Centisome position: 21.25

GC content: 70.12

Gene sequence:

>1101_bases
ATGAGCGCGGCGGAACCTTGGAAGGTGGAGGGGGGCAGGACGGTCATCTTCGGCGGCGCCGGCTTCATCGGCTCCAACCT
GGCGGACCACTACCTGTCCGCGGGGCGGACCGTGCGCGTCGTCGATAACCTGACGCGCCCCGGGGTGGTGCACAACCTGC
GTTGGCTCCAGGCCCGGCATGGCGCCCGGCTGGAGGTGGTGACGGCGGACGTACGGGACGCCCATGCGGTGAAGCAATCC
GTCGTTGGCGCCAGCGAGGTCTTCCACTTCGCGGCCCAGGGGGCTGTCACCACCAGCCTGGAGACGCCCGTCACCGACTT
CGAGGTCAACGCGGGCGGCACCCTGAACGTGCTGGAGGCGCTGCGCGCCATGGAGCGGCCTGCCTCGCTCGTCTTCACCT
CCACCAACAAGGTCTACGGTTGCACGCCGGGCGTGGAGTTCGTCCAGAAGCCCAGCCGCTACGCGCCTCGGGACGCGGGC
CTGCGCGGTCACGGCGTGGGGGAGGACTGCCCGGTGGACTTCGAGAGCCCCGATGGCTGCTCCAAGGGCGCGGCGGACCA
GTACGTGCTCGACTACGCGCGGGCTTACGGGCTGAGGACGGTGGTGTTCCGGATGAGCTGCATCTACGGCCCCCGGCAGT
TCGGCACCGAGGACCAGGGCTGGGTGGCGCACTTCCTCCTGTGCATGCTCGAAGGCCGGCCCCTCACGCTCTACGGAGAT
GGCAAGCAGGTACGCGACATCCTCGATGTGGGGGACCTGGTGCGCGCGCTCGGCCTGGCGCAGCAGCACATCGGACGGCT
CAAGGGGCAGGCCTTCAACATTGGCGGCGGCCCGTCGCGGACAGTGAGCCTGTTGGACTTGCTGGGGCTCATCTCTCAGC
GCACCGGTCTGCGGCCCGCGCTCCAGTTCGAGGATGGGCGGACGGGGGACCCGCGCTACTACGTCTCCGACCCCCGCAAG
TTCCAGGCAGCCACGGGGTGGGCGCCCCAGGTGGGAATCGCCGAGGGCGTGGACCGGCTCCACGACTGGCTGCGGACCCT
GATGCTCGAGCGGCCAGTGGCGTCCGGGCAGGGAGGGGCGCGTGAAGTCCTCGTAGGCTAG

Upstream 100 bases:

>100_bases
ACGACGGGCTCGCGGAGCTGTCGTCGTGGCTCGAGGACCAGGTGGCGACGGACCGCGTGGCGGAGGCGCGCGCGGAACTC
GAGACGCGAGGGCTGACCGT

Downstream 100 bases:

>100_bases
AGGGCGCGCCGTCCGCCGTGTGCTGACGTGCTCGACCCGCGGCTCGCCTGGAGCGAGGGCGTCACCTACATCGGCATCGG
GCGCGACTGACGCACGGCTC

Product: CDP-tyvelose-2-epimerase

Products: NA

Alternate protein names: CDP-tyvelose 2-epimerase [H]

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MSAAEPWKVEGGRTVIFGGAGFIGSNLADHYLSAGRTVRVVDNLTRPGVVHNLRWLQARHGARLEVVTADVRDAHAVKQS
VVGASEVFHFAAQGAVTTSLETPVTDFEVNAGGTLNVLEALRAMERPASLVFTSTNKVYGCTPGVEFVQKPSRYAPRDAG
LRGHGVGEDCPVDFESPDGCSKGAADQYVLDYARAYGLRTVVFRMSCIYGPRQFGTEDQGWVAHFLLCMLEGRPLTLYGD
GKQVRDILDVGDLVRALGLAQQHIGRLKGQAFNIGGGPSRTVSLLDLLGLISQRTGLRPALQFEDGRTGDPRYYVSDPRK
FQAATGWAPQVGIAEGVDRLHDWLRTLMLERPVASGQGGAREVLVG

Sequences:

>Translated_366_residues
MSAAEPWKVEGGRTVIFGGAGFIGSNLADHYLSAGRTVRVVDNLTRPGVVHNLRWLQARHGARLEVVTADVRDAHAVKQS
VVGASEVFHFAAQGAVTTSLETPVTDFEVNAGGTLNVLEALRAMERPASLVFTSTNKVYGCTPGVEFVQKPSRYAPRDAG
LRGHGVGEDCPVDFESPDGCSKGAADQYVLDYARAYGLRTVVFRMSCIYGPRQFGTEDQGWVAHFLLCMLEGRPLTLYGD
GKQVRDILDVGDLVRALGLAQQHIGRLKGQAFNIGGGPSRTVSLLDLLGLISQRTGLRPALQFEDGRTGDPRYYVSDPRK
FQAATGWAPQVGIAEGVDRLHDWLRTLMLERPVASGQGGAREVLVG
>Mature_365_residues
SAAEPWKVEGGRTVIFGGAGFIGSNLADHYLSAGRTVRVVDNLTRPGVVHNLRWLQARHGARLEVVTADVRDAHAVKQSV
VGASEVFHFAAQGAVTTSLETPVTDFEVNAGGTLNVLEALRAMERPASLVFTSTNKVYGCTPGVEFVQKPSRYAPRDAGL
RGHGVGEDCPVDFESPDGCSKGAADQYVLDYARAYGLRTVVFRMSCIYGPRQFGTEDQGWVAHFLLCMLEGRPLTLYGDG
KQVRDILDVGDLVRALGLAQQHIGRLKGQAFNIGGGPSRTVSLLDLLGLISQRTGLRPALQFEDGRTGDPRYYVSDPRKF
QAATGWAPQVGIAEGVDRLHDWLRTLMLERPVASGQGGAREVLVG

Specific function: Catalyzes the isomeration of CDP-paratose to CDP- tyvelose [H]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=340, Percent_Identity=28.5294117647059, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI7657641, Length=365, Percent_Identity=27.3972602739726, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI56237023, Length=356, Percent_Identity=25.561797752809, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI56118217, Length=356, Percent_Identity=25.561797752809, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI189083684, Length=356, Percent_Identity=25.561797752809, Blast_Score=79, Evalue=7e-15,
Organism=Escherichia coli, GI1788353, Length=355, Percent_Identity=29.8591549295775, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI48994969, Length=353, Percent_Identity=28.6118980169972, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1786974, Length=339, Percent_Identity=25.0737463126844, Blast_Score=81, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17539532, Length=345, Percent_Identity=26.3768115942029, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17568069, Length=355, Percent_Identity=26.4788732394366, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI115532424, Length=341, Percent_Identity=27.2727272727273, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI21356223, Length=343, Percent_Identity=27.1137026239067, Blast_Score=95, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.10 [H]

Molecular weight: Translated: 39502; Mature: 39371

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAAEPWKVEGGRTVIFGGAGFIGSNLADHYLSAGRTVRVVDNLTRPGVVHNLRWLQARH
CCCCCCCEECCCCEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHCC
GARLEVVTADVRDAHAVKQSVVGASEVFHFAAQGAVTTSLETPVTDFEVNAGGTLNVLEA
CCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEEECCCCHHHHHHH
LRAMERPASLVFTSTNKVYGCTPGVEFVQKPSRYAPRDAGLRGHGVGEDCPVDFESPDGC
HHHHCCCCEEEEEECCCEEECCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SKGAADQYVLDYARAYGLRTVVFRMSCIYGPRQFGTEDQGWVAHFLLCMLEGRPLTLYGD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHCCCEEEEECC
GKQVRDILDVGDLVRALGLAQQHIGRLKGQAFNIGGGPSRTVSLLDLLGLISQRTGLRPA
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCE
LQFEDGRTGDPRYYVSDPRKFQAATGWAPQVGIAEGVDRLHDWLRTLMLERPVASGQGGA
EEECCCCCCCCCEEECCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
REVLVG
CCCCCC
>Mature Secondary Structure 
SAAEPWKVEGGRTVIFGGAGFIGSNLADHYLSAGRTVRVVDNLTRPGVVHNLRWLQARH
CCCCCCEECCCCEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHCC
GARLEVVTADVRDAHAVKQSVVGASEVFHFAAQGAVTTSLETPVTDFEVNAGGTLNVLEA
CCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEEECCCCHHHHHHH
LRAMERPASLVFTSTNKVYGCTPGVEFVQKPSRYAPRDAGLRGHGVGEDCPVDFESPDGC
HHHHCCCCEEEEEECCCEEECCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SKGAADQYVLDYARAYGLRTVVFRMSCIYGPRQFGTEDQGWVAHFLLCMLEGRPLTLYGD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHCCCEEEEECC
GKQVRDILDVGDLVRALGLAQQHIGRLKGQAFNIGGGPSRTVSLLDLLGLISQRTGLRPA
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCE
LQFEDGRTGDPRYYVSDPRKFQAATGWAPQVGIAEGVDRLHDWLRTLMLERPVASGQGGA
EEECCCCCCCCCEEECCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
REVLVG
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2793833; 11677608; 12644504; 12642575 [H]