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The map label for this gene is sppA [H]

Identifier: 108758821

GI number: 108758821

Start: 2887736

End: 2890234

Strand: Reverse

Name: sppA [H]

Synonym: MXAN_2480

Alternate gene names: 108758821

Gene position: 2890234-2887736 (Counterclockwise)

Preceding gene: 108763440

Following gene: 108757528

Centisome position: 31.62

GC content: 71.83

Gene sequence:

>2499_bases
ATGCCTAGAGTCCCGGGGCGTATGCGCCTGCTCGCCCTCCTGCTCCTCCCCAGCCTCGCGCTCGCCCAGACGAGTGTCGT
CAGCCAGCCCGCCCTGCCCTCCCGGGGGCTGGCGCTGCCGCCCACGGGCGCCGCGCTGGTGGATGAAGCCACCGCCCTGT
CGCTCAACCCCGCGGGCCTGGGCTTCGTCAACGGCAGTCAGCTCTTCTACCTGCACGAGCGCAACCTCGTGCATGACGGC
CTGGGAGACGGCGTCTTCCTGGCCACGCGCCTGCTCGGCCTGGGCCTGGGCGGCGCCATGGAGTGGATTCGCGGACGGGC
GGAGCCGGACTACCGCCGCACGTCCCTGGGTCTCTCCCTGGGCACGCGCACGCTGCAGCTCGGCGGTTCGTGGCACGCCT
ACGGTTCATCCCACCGGGACATCGACGCGCTGGACACCTTCGACGTGGGCCTCACGGCGCGCCCCATGCGGGCGCTGTCG
CTGGGCGCGGTGGTGCGCGACATCAACGCCCCCACCGAGGGCACGCTGGCACTGAAGCGGCAGTACAACCTGGGCGTGGG
CGTGCGCCCGCTGGATGAGCGCTACACGCTGGGCGTGGACTGGCTCTTCTCCGAGGGCGCCTTCCGCCAGGGCCAGGCGA
CGTACACCGTCAACGCGGAGGTGATTCCGGGCCTCCGCCTGGGCGCGGGCGTGTCGCACGGCTTCACCTCCGGGGTGCCC
ATCGCGCTCCAGGTGGCGGCCACGGTGGACACCTCGCACCTGGGCCTCACCTACGCGGCGGGCGGGACGAATGCGGGGCT
GGACCACCTGGTGGCGGTGCGCCTGTCGTCGGAGACCTACCGCTCCATCGCGCCGCGCGGCGGCGTGGTGACGCTGCTGG
ACTTGAATGACGCATTGAGCGGCGGCACCAGCCCCGTCCTCTCATGGTTGGGCGTCACCGAGGCGGACCCGTACCTGCGG
CTGACGCGGTGGCTGGACCTGGCCACCCAGGACGACCGGCTGGCCGGCGTGGTGGTGAAGATGGAGAGCCTGCCCGGGGT
GAGCTGGGGCAAGGCGGAGGAGCTGCGTCAGGCGCTGCTGCGGCTGCGCGCGTCCGGCAAGCGGGTGATGGCGGTGGTGC
TGTCCACGGACGACCTGGGCTACTTCGTTGCCTCGGCGGCGGACCGCATCTACGCGCTGCAGGAGTCGATTCTCTACATC
AACGGCCTGGCCGTGCACCTCCAGACGTACGGCGGGACGATGGAGAAGCTGGGCGTGCACTGGGACGTGGCGCGCGTGGG
CCGCTTCAAGACGGCCCCGGAGCAGCTTTCCCGCACCGAGCCCAGCGACGCGTCCTTGGAGTCCACGAACGCCTACCTGG
ACACGGAGGTGGCCGTCTACGAGAAAGCCGTGCAGGAGGGCCGCAAGGTGCCCGTGGAGCGGCTGCACGCGCTGTGGGCA
CTGGGCCTGCCCCATCCGAAGCGCGCGGTGGAGCTGGGGTTGATGGACGGCATCATCTCCTCGACGGAGCTGGACAAGAA
GGTGGCGGAGCTGGTGCCGGGTGGACGCTTCAGCACCACGTACGCGCCGCGCGACGAGCGCGACGGCCGCTGGGCCCGCC
GGCGCCGCATCGCCGTGGTGCCGGTGCTGGGCGACATCATCGGCGGCCGCAGCCGCGAGGACCCGCTGGGCTTCAGCCGC
CTCGCGGGCGCGGAGACAGTCATTCGCGCGCTGGAGCAGGCGCAGTCGGACCCGAGCGTGGCGGCCATCGTCGTGCGCGT
GGACTCGGGCGGCGGCGAGGTGCTGGCGTCCCACCTGATGTACGAAGCCGTGATGGAGGCGGCCAAACACAAGCCCGTCG
TCGCCTCCATGGGAGACATGGCCGCGTCCGGTGGCTACTACGCCGCCATTGGCGCGCACGAGGTGTTCGCCCTGCCCACC
ACGCTGACGGGCAGCATCGGCGTCTTCTACATCAAGCCCGCCGTCGAGGGCCTGCTGAGCGGGCTGTTGGGCGTGCACCA
GGAGAGCCTGACCCGCGCGCCGCTGGCGGACATCCTGGACGTGTGGCGCCCCTGGACGCCGGAGGAGCAGGAGGCGGCCC
AGGCGTGGGCGGACGCCTCCTACGACAGCTTCATCACCGAGGTGGCGCTGCGGCGGAGGATGGACAAGGCGAAGGTGGAC
GAGGTCGCCCGGGGCCGGGTGTGGAGCGGCCAGGACGCGCTCGCCCGCGGACTGGTGGACAAGCTGGGTGGCCTGCTGGA
AGCGGTGGACTCCGCGCGGATGCGGGCCGGAATCCCTCCGGACGAGGAGCTGGACCTGGTGGTGATGGGCGAGGCGCGGG
GCTTCTTCTCCGCGCTGGGCGGTGAGCCCGGGGTGCGCGCCGCGCTGTCCCTGCTGCCCGCACAAGAGCCCGCCCTGCCT
GAGTCCCTGCGGGCGCTGGCCCGCTCGGCCGGCCTGAATCTGATGTTGCTCCAGCCGGGCGTGAAGGCGATGTTGCCCTT
CCAGATAACCGTCCGCTGA

Upstream 100 bases:

>100_bases
CAAGGCGCAGGACAAGAAGAGCAAGCCCGGCGACGACCCGCTCGACGGTGTGTCCGGAACCGAGGACTGGTAACGCTGAG
CGCTTGTCCCGGGACGGCTG

Downstream 100 bases:

>100_bases
GGTCCTGGCGGCGGCCCTGAATCAACAGGTGGGGGGTCGGCCGGACGACACCGCGCGAAAAAAGCGGCGGCGCCGTCCCC
GGCCTCTGTTACTGTTACCC

Product: signal peptide peptidase SppA, 36K type

Products: NA

Alternate protein names: Endopeptidase IV; Protease IV; Signal peptide peptidase [H]

Number of amino acids: Translated: 832; Mature: 831

Protein sequence:

>832_residues
MPRVPGRMRLLALLLLPSLALAQTSVVSQPALPSRGLALPPTGAALVDEATALSLNPAGLGFVNGSQLFYLHERNLVHDG
LGDGVFLATRLLGLGLGGAMEWIRGRAEPDYRRTSLGLSLGTRTLQLGGSWHAYGSSHRDIDALDTFDVGLTARPMRALS
LGAVVRDINAPTEGTLALKRQYNLGVGVRPLDERYTLGVDWLFSEGAFRQGQATYTVNAEVIPGLRLGAGVSHGFTSGVP
IALQVAATVDTSHLGLTYAAGGTNAGLDHLVAVRLSSETYRSIAPRGGVVTLLDLNDALSGGTSPVLSWLGVTEADPYLR
LTRWLDLATQDDRLAGVVVKMESLPGVSWGKAEELRQALLRLRASGKRVMAVVLSTDDLGYFVASAADRIYALQESILYI
NGLAVHLQTYGGTMEKLGVHWDVARVGRFKTAPEQLSRTEPSDASLESTNAYLDTEVAVYEKAVQEGRKVPVERLHALWA
LGLPHPKRAVELGLMDGIISSTELDKKVAELVPGGRFSTTYAPRDERDGRWARRRRIAVVPVLGDIIGGRSREDPLGFSR
LAGAETVIRALEQAQSDPSVAAIVVRVDSGGGEVLASHLMYEAVMEAAKHKPVVASMGDMAASGGYYAAIGAHEVFALPT
TLTGSIGVFYIKPAVEGLLSGLLGVHQESLTRAPLADILDVWRPWTPEEQEAAQAWADASYDSFITEVALRRRMDKAKVD
EVARGRVWSGQDALARGLVDKLGGLLEAVDSARMRAGIPPDEELDLVVMGEARGFFSALGGEPGVRAALSLLPAQEPALP
ESLRALARSAGLNLMLLQPGVKAMLPFQITVR

Sequences:

>Translated_832_residues
MPRVPGRMRLLALLLLPSLALAQTSVVSQPALPSRGLALPPTGAALVDEATALSLNPAGLGFVNGSQLFYLHERNLVHDG
LGDGVFLATRLLGLGLGGAMEWIRGRAEPDYRRTSLGLSLGTRTLQLGGSWHAYGSSHRDIDALDTFDVGLTARPMRALS
LGAVVRDINAPTEGTLALKRQYNLGVGVRPLDERYTLGVDWLFSEGAFRQGQATYTVNAEVIPGLRLGAGVSHGFTSGVP
IALQVAATVDTSHLGLTYAAGGTNAGLDHLVAVRLSSETYRSIAPRGGVVTLLDLNDALSGGTSPVLSWLGVTEADPYLR
LTRWLDLATQDDRLAGVVVKMESLPGVSWGKAEELRQALLRLRASGKRVMAVVLSTDDLGYFVASAADRIYALQESILYI
NGLAVHLQTYGGTMEKLGVHWDVARVGRFKTAPEQLSRTEPSDASLESTNAYLDTEVAVYEKAVQEGRKVPVERLHALWA
LGLPHPKRAVELGLMDGIISSTELDKKVAELVPGGRFSTTYAPRDERDGRWARRRRIAVVPVLGDIIGGRSREDPLGFSR
LAGAETVIRALEQAQSDPSVAAIVVRVDSGGGEVLASHLMYEAVMEAAKHKPVVASMGDMAASGGYYAAIGAHEVFALPT
TLTGSIGVFYIKPAVEGLLSGLLGVHQESLTRAPLADILDVWRPWTPEEQEAAQAWADASYDSFITEVALRRRMDKAKVD
EVARGRVWSGQDALARGLVDKLGGLLEAVDSARMRAGIPPDEELDLVVMGEARGFFSALGGEPGVRAALSLLPAQEPALP
ESLRALARSAGLNLMLLQPGVKAMLPFQITVR
>Mature_831_residues
PRVPGRMRLLALLLLPSLALAQTSVVSQPALPSRGLALPPTGAALVDEATALSLNPAGLGFVNGSQLFYLHERNLVHDGL
GDGVFLATRLLGLGLGGAMEWIRGRAEPDYRRTSLGLSLGTRTLQLGGSWHAYGSSHRDIDALDTFDVGLTARPMRALSL
GAVVRDINAPTEGTLALKRQYNLGVGVRPLDERYTLGVDWLFSEGAFRQGQATYTVNAEVIPGLRLGAGVSHGFTSGVPI
ALQVAATVDTSHLGLTYAAGGTNAGLDHLVAVRLSSETYRSIAPRGGVVTLLDLNDALSGGTSPVLSWLGVTEADPYLRL
TRWLDLATQDDRLAGVVVKMESLPGVSWGKAEELRQALLRLRASGKRVMAVVLSTDDLGYFVASAADRIYALQESILYIN
GLAVHLQTYGGTMEKLGVHWDVARVGRFKTAPEQLSRTEPSDASLESTNAYLDTEVAVYEKAVQEGRKVPVERLHALWAL
GLPHPKRAVELGLMDGIISSTELDKKVAELVPGGRFSTTYAPRDERDGRWARRRRIAVVPVLGDIIGGRSREDPLGFSRL
AGAETVIRALEQAQSDPSVAAIVVRVDSGGGEVLASHLMYEAVMEAAKHKPVVASMGDMAASGGYYAAIGAHEVFALPTT
LTGSIGVFYIKPAVEGLLSGLLGVHQESLTRAPLADILDVWRPWTPEEQEAAQAWADASYDSFITEVALRRRMDKAKVDE
VARGRVWSGQDALARGLVDKLGGLLEAVDSARMRAGIPPDEELDLVVMGEARGFFSALGGEPGVRAALSLLPAQEPALPE
SLRALARSAGLNLMLLQPGVKAMLPFQITVR

Specific function: Digestion of the cleaved signal peptides. This activity is necessary to maintain proper secretion of mature proteins across the membrane [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1788064, Length=444, Percent_Identity=33.3333333333333, Blast_Score=194, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004634
- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 88859; Mature: 88728

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRVPGRMRLLALLLLPSLALAQTSVVSQPALPSRGLALPPTGAALVDEATALSLNPAGL
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCEEEECCCCC
GFVNGSQLFYLHERNLVHDGLGDGVFLATRLLGLGLGGAMEWIRGRAEPDYRRTSLGLSL
EEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHCCEE
GTRTLQLGGSWHAYGSSHRDIDALDTFDVGLTARPMRALSLGAVVRDINAPTEGTLALKR
CCEEEEECCCEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEE
QYNLGVGVRPLDERYTLGVDWLFSEGAFRQGQATYTVNAEVIPGLRLGAGVSHGFTSGVP
ECCCCCCCCCCCCCEEECEEEEECCCCCCCCCEEEEEECEECCCEEECCCCCCCCCCCCC
IALQVAATVDTSHLGLTYAAGGTNAGLDHLVAVRLSSETYRSIAPRGGVVTLLDLNDALS
EEEEEEEEECCCCCCEEEECCCCCCCCHHEEEEEECCHHHHHHCCCCCEEEEEECCHHCC
GGTSPVLSWLGVTEADPYLRLTRWLDLATQDDRLAGVVVKMESLPGVSWGKAEELRQALL
CCCHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHH
RLRASGKRVMAVVLSTDDLGYFVASAADRIYALQESILYINGLAVHLQTYGGTMEKLGVH
HHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHEEEEEEEEEEEEECCCCHHHHCCE
WDVARVGRFKTAPEQLSRTEPSDASLESTNAYLDTEVAVYEKAVQEGRKVPVERLHALWA
ECHHHHCCCCCCHHHHHCCCCCCCCCCCCCCEECHHHHHHHHHHHCCCCCCHHHHHHHHH
LGLPHPKRAVELGLMDGIISSTELDKKVAELVPGGRFSTTYAPRDERDGRWARRRRIAVV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCEEEE
PVLGDIIGGRSREDPLGFSRLAGAETVIRALEQAQSDPSVAAIVVRVDSGGGEVLASHLM
EEHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHCCCCCEEEEEEEEECCCHHHHHHHHH
YEAVMEAAKHKPVVASMGDMAASGGYYAAIGAHEVFALPTTLTGSIGVFYIKPAVEGLLS
HHHHHHHHHCCCEEEECCCHHCCCCEEEEECCCEEEEECCCCCCCCEEEEECHHHHHHHH
GLLGVHQESLTRAPLADILDVWRPWTPEEQEAAQAWADASYDSFITEVALRRRMDKAKVD
HHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
EVARGRVWSGQDALARGLVDKLGGLLEAVDSARMRAGIPPDEELDLVVMGEARGFFSALG
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHC
GEPGVRAALSLLPAQEPALPESLRALARSAGLNLMLLQPGVKAMLPFQITVR
CCCCHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCEECCEEEEEC
>Mature Secondary Structure 
PRVPGRMRLLALLLLPSLALAQTSVVSQPALPSRGLALPPTGAALVDEATALSLNPAGL
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCEEEECCCCC
GFVNGSQLFYLHERNLVHDGLGDGVFLATRLLGLGLGGAMEWIRGRAEPDYRRTSLGLSL
EEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHCCEE
GTRTLQLGGSWHAYGSSHRDIDALDTFDVGLTARPMRALSLGAVVRDINAPTEGTLALKR
CCEEEEECCCEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEE
QYNLGVGVRPLDERYTLGVDWLFSEGAFRQGQATYTVNAEVIPGLRLGAGVSHGFTSGVP
ECCCCCCCCCCCCCEEECEEEEECCCCCCCCCEEEEEECEECCCEEECCCCCCCCCCCCC
IALQVAATVDTSHLGLTYAAGGTNAGLDHLVAVRLSSETYRSIAPRGGVVTLLDLNDALS
EEEEEEEEECCCCCCEEEECCCCCCCCHHEEEEEECCHHHHHHCCCCCEEEEEECCHHCC
GGTSPVLSWLGVTEADPYLRLTRWLDLATQDDRLAGVVVKMESLPGVSWGKAEELRQALL
CCCHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHH
RLRASGKRVMAVVLSTDDLGYFVASAADRIYALQESILYINGLAVHLQTYGGTMEKLGVH
HHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHEEEEEEEEEEEEECCCCHHHHCCE
WDVARVGRFKTAPEQLSRTEPSDASLESTNAYLDTEVAVYEKAVQEGRKVPVERLHALWA
ECHHHHCCCCCCHHHHHCCCCCCCCCCCCCCEECHHHHHHHHHHHCCCCCCHHHHHHHHH
LGLPHPKRAVELGLMDGIISSTELDKKVAELVPGGRFSTTYAPRDERDGRWARRRRIAVV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCEEEE
PVLGDIIGGRSREDPLGFSRLAGAETVIRALEQAQSDPSVAAIVVRVDSGGGEVLASHLM
EEHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHCCCCCEEEEEEEEECCCHHHHHHHHH
YEAVMEAAKHKPVVASMGDMAASGGYYAAIGAHEVFALPTTLTGSIGVFYIKPAVEGLLS
HHHHHHHHHCCCEEEECCCHHCCCCEEEEECCCEEEEECCCCCCCCEEEEECHHHHHHHH
GLLGVHQESLTRAPLADILDVWRPWTPEEQEAAQAWADASYDSFITEVALRRRMDKAKVD
HHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
EVARGRVWSGQDALARGLVDKLGGLLEAVDSARMRAGIPPDEELDLVVMGEARGFFSALG
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHC
GEPGVRAALSLLPAQEPALPESLRALARSAGLNLMLLQPGVKAMLPFQITVR
CCCCHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCEECCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3522590; 9097039; 9278503; 7973728 [H]