Click here to switch to the map view.

The map label for this gene is yfjP [H]

Identifier: 108758816

GI number: 108758816

Start: 1828401

End: 1829075

Strand: Direct

Name: yfjP [H]

Synonym: MXAN_1556

Alternate gene names: 108758816

Gene position: 1828401-1829075 (Clockwise)

Preceding gene: 108757616

Following gene: 108761529

Centisome position: 20.0

GC content: 68.59

Gene sequence:

>675_bases
ATGCCGCGTCCTCCTCCCGACGTCATTCGATACCCCAGCTACTACACGCCCTCGGTCCGCCGTGCCCTGTCGCGCGCGGA
CCCGACGCTGGGCGCGTTGATGAAGAGCGTTGGCCCCTTCCGGCTCCAGGTGCGTCCGCTGCACAGCCCCTTCGGTGCGC
TGGCGGAGTCCATCGTCTACCAGCAGCTCCACGGCAAGGCGGCCGCCACCATCTTCGGTCGCGTGTGCGAGCGCGTGGGC
TCGGGACGCAAGTTCACGCCGGAAGCGCTGCTGGCCGTTCCGGACACGTCGCTGCGCGAAGCGGGACTGTCCGCCAACAA
GCTGGCCGCGCTCCAGGACCTGGCGCGCAAGACGCTGGACGGCACCGTGCCTCCGCTGGCCAAGGTGCGGCGCATGGATG
ACGCCGAGCTCATCGAGCACTTCACCCAGGTGCGTGGCATTGGCCAGTGGACGGTGGAGATGCTGCTCATGTTCCAACTC
GAGCGGCCTGACGTGCTGCCCGTGGACGACTACGGCGTGCGCAAGGGCTTCATGAAGGCCTATGGCCTGACGGAGATGCC
CAAGCCCAAGGCGCTGCTTGCTTATGGCGAACGCTGGCGGCCCTGGCGCTCGGTGGCCAGTTGGTACATGTGGCGCTCGG
CGGAGCTCCCCGACGCGCCGACCGTGGAGGGCTGA

Upstream 100 bases:

>100_bases
GCCGAGACGGAGCACGCCGCGCCGATTTGAGCGGCGGCGGCTTGTCGCAAGAATCGGGTTGCGTGAAGGGGGCTGGGCGG
CGGCATCATGGTCGCCGCCC

Downstream 100 bases:

>100_bases
CGGCGTTTCTGGGCTGTGGCCTCAGGCGGTGTTGAGCGTGGTGCTCGGGGCGTGCTTCTGGCGCCGCATGGGCACCAGCA
GCACCAGGAAGGCCACGGAC

Product: putative DNA-3-methyladenine glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MPRPPPDVIRYPSYYTPSVRRALSRADPTLGALMKSVGPFRLQVRPLHSPFGALAESIVYQQLHGKAAATIFGRVCERVG
SGRKFTPEALLAVPDTSLREAGLSANKLAALQDLARKTLDGTVPPLAKVRRMDDAELIEHFTQVRGIGQWTVEMLLMFQL
ERPDVLPVDDYGVRKGFMKAYGLTEMPKPKALLAYGERWRPWRSVASWYMWRSAELPDAPTVEG

Sequences:

>Translated_224_residues
MPRPPPDVIRYPSYYTPSVRRALSRADPTLGALMKSVGPFRLQVRPLHSPFGALAESIVYQQLHGKAAATIFGRVCERVG
SGRKFTPEALLAVPDTSLREAGLSANKLAALQDLARKTLDGTVPPLAKVRRMDDAELIEHFTQVRGIGQWTVEMLLMFQL
ERPDVLPVDDYGVRKGFMKAYGLTEMPKPKALLAYGERWRPWRSVASWYMWRSAELPDAPTVEG
>Mature_223_residues
PRPPPDVIRYPSYYTPSVRRALSRADPTLGALMKSVGPFRLQVRPLHSPFGALAESIVYQQLHGKAAATIFGRVCERVGS
GRKFTPEALLAVPDTSLREAGLSANKLAALQDLARKTLDGTVPPLAKVRRMDDAELIEHFTQVRGIGQWTVEMLLMFQLE
RPDVLPVDDYGVRKGFMKAYGLTEMPKPKALLAYGERWRPWRSVASWYMWRSAELPDAPTVEG

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, 3-methylguanine, 7-methylguanine, O2- methylthymine, and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG0122

COG function: function code L; 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alkylbase DNA glycosidase alkA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003265
- InterPro:   IPR003583
- InterPro:   IPR023170 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: =3.2.2.21 [H]

Molecular weight: Translated: 25061; Mature: 24930

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRPPPDVIRYPSYYTPSVRRALSRADPTLGALMKSVGPFRLQVRPLHSPFGALAESIVY
CCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHH
QQLHGKAAATIFGRVCERVGSGRKFTPEALLAVPDTSLREAGLSANKLAALQDLARKTLD
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEECCCCHHHHHCCCHHHHHHHHHHHHHHHC
GTVPPLAKVRRMDDAELIEHFTQVRGIGQWTVEMLLMFQLERPDVLPVDDYGVRKGFMKA
CCCCHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
YGLTEMPKPKALLAYGERWRPWRSVASWYMWRSAELPDAPTVEG
HCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
PRPPPDVIRYPSYYTPSVRRALSRADPTLGALMKSVGPFRLQVRPLHSPFGALAESIVY
CCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHH
QQLHGKAAATIFGRVCERVGSGRKFTPEALLAVPDTSLREAGLSANKLAALQDLARKTLD
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEECCCCHHHHHCCCHHHHHHHHHHHHHHHC
GTVPPLAKVRRMDDAELIEHFTQVRGIGQWTVEMLLMFQLERPDVLPVDDYGVRKGFMKA
CCCCHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
YGLTEMPKPKALLAYGERWRPWRSVASWYMWRSAELPDAPTVEG
HCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]