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The map label for this gene is 108758638

Identifier: 108758638

GI number: 108758638

Start: 1739517

End: 1741157

Strand: Reverse

Name: 108758638

Synonym: MXAN_1479

Alternate gene names: NA

Gene position: 1741157-1739517 (Counterclockwise)

Preceding gene: 108761750

Following gene: 108758044

Centisome position: 19.05

GC content: 71.6

Gene sequence:

>1641_bases
ATGCTTCACGTCATTCCCCTGGGCGGCCTGGGCGAAATCGGCCTCAACTCCATGGTCATCGCCTGCCGTGGGGAGATGCT
GCTCATCGACGCCGGGCTGATGTTCCCCTCCGCGGGGATGCCCGGCGTGGACATCATCATTCCGGACTTCAGCCACCTGA
AGCAGAACGCCGCGCAGCTCAAGGGCGTGCTGCTCACCCATGGCCACGAAGACCACCTGGGCGCCCTGCCCTACCTGCTC
AACGAGGTGCCCGTCCCCGTCTACGGCACGCGCTTCACACTGGCCATGGCGCGCCACCGGCTGGAGGAGCTGGGCATCGA
GGCGGACCTGCGCGAAATCGAGCCGCGCGAGCCCTTCCCCGTGGGCACGGCGTTCCGCGTGGAGGCCAGCCGCGTCACCC
ACACCGTGCCGGACGCGGTGGGCTACATCCTGCGCACGCCCGAAGGCACCCTCATCCACACCGGCGACTTCAAGCTGGAC
CCGGACCCCATCGACGGGCTGCGCACGGACCTGGAGCGCTGGGGCGAGGCCGGCGAGGAAGGCGTGCTGTGCCTCCTCTC
CGACTCCACCAACTCCGAGGTGACGGAGGAGACAGGCAGCGAGCGCGTGGTGGAGCAGACCTTCGAGCGCCTCTTCCAGG
GCGCCACCGGCCGCATCATCGTCGCCCTCTTCTCCTCCAACCTCCACCGGGTGCGGCACCTGCTGGCGCTGGCGGAGCGG
CTGGGACGCAAGGTGGCCCTGCAGGGCCGCAGCATGCTGCGCAACGTGGAGATGGCGCGGGAGATGGGCTACCTGGACGT
GCCCGACTCGCTCTTCGTCCACCTGGACTCGGTGCCGGCGCTGCCCGCGCAGCGGGTGCTGGTGCTGACCACCGGCGCCC
AGGGCGAGCCCCGGGCCGGGCTGTCCCAGCTCGCGTCGGGGGACGGCCCCGTGCGGCTGAATCCCGGCGACCTGGTGGTG
CTCAGCTCGCGGGCCATCCCCGGCAACGAGCGCTCCGTGGGCGCGCTCATCGACGCGCTCCAGTGGCGCGGGGCGAAAGT
CGCCTACGCCCAGGTGGAGCCGGGCATCCACGTCTCCGGCCACGCCAGCCAGCCCCAGCAGCGGCGCGTGCTGGACCTGG
TGCGCCCGGCCCACTTCATCCCCGTCCACGGCGAGGGCCGCCATCTGCACAAGCACCTGCTCACCGCGCGCGAGGCCGGG
CTGGAGCCCGCCCAGTGCCTGCTGGCACAGGACGGCGACGTCGTCACCTTCGAGGAAGGCCGGGGGCGCTTCACCGGCAG
CGTCCCGTCCGGACGCATCCTCAAGGACCGGTTCGGCCCCGGCCTGGTGACGCCGGACACGCTCCAGGAGCGCGTCCGGC
TGTCGGAGACGGGCATGGTGGCCGCGGTGGTGGTCCTCCAGCGGGGCTCCCAGCAACTGGTGGCGGGGCCACAGCTGTCC
GGCCAGGGGCTGTCCGTGGACGAACAGGTCCTGCTCCCCCGGGTGGCCCAGGACGCGCGAGTGCTCTTCGAGGAACTGTC
CCCCATCCTGCGGGGCGATGACGCCCTGGTGAGAGAGGAACTCACCCGGGCCGTGCGCCGGGCATTCAAGGCGCACACGT
CCAAGCGTGCCCTGGTGGTGCCCTTGGTCGTCCGGGTGTAG

Upstream 100 bases:

>100_bases
CGCATCTGATGAAGTCACCCCGAGGGCCGCCAGACAGGCGGACGCGGCTCACGTCCATTCTCGGGGGCTTCCGTCACTTT
CCACCGCTAGACTTCGCCCA

Downstream 100 bases:

>100_bases
GTATGGTAAGGGCCGCTGCCCATGCCATCCTTCGACGTCGTCTCGAAAATCGACCTCGCTGAGCTCGACAACGCGGTCAA
CCAGACCAAGAAGGAGCTCA

Product: metallo-beta-lactamase family protein

Products: NA

Alternate protein names: RNase J [H]

Number of amino acids: Translated: 546; Mature: 546

Protein sequence:

>546_residues
MLHVIPLGGLGEIGLNSMVIACRGEMLLIDAGLMFPSAGMPGVDIIIPDFSHLKQNAAQLKGVLLTHGHEDHLGALPYLL
NEVPVPVYGTRFTLAMARHRLEELGIEADLREIEPREPFPVGTAFRVEASRVTHTVPDAVGYILRTPEGTLIHTGDFKLD
PDPIDGLRTDLERWGEAGEEGVLCLLSDSTNSEVTEETGSERVVEQTFERLFQGATGRIIVALFSSNLHRVRHLLALAER
LGRKVALQGRSMLRNVEMAREMGYLDVPDSLFVHLDSVPALPAQRVLVLTTGAQGEPRAGLSQLASGDGPVRLNPGDLVV
LSSRAIPGNERSVGALIDALQWRGAKVAYAQVEPGIHVSGHASQPQQRRVLDLVRPAHFIPVHGEGRHLHKHLLTAREAG
LEPAQCLLAQDGDVVTFEEGRGRFTGSVPSGRILKDRFGPGLVTPDTLQERVRLSETGMVAAVVVLQRGSQQLVAGPQLS
GQGLSVDEQVLLPRVAQDARVLFEELSPILRGDDALVREELTRAVRRAFKAHTSKRALVVPLVVRV

Sequences:

>Translated_546_residues
MLHVIPLGGLGEIGLNSMVIACRGEMLLIDAGLMFPSAGMPGVDIIIPDFSHLKQNAAQLKGVLLTHGHEDHLGALPYLL
NEVPVPVYGTRFTLAMARHRLEELGIEADLREIEPREPFPVGTAFRVEASRVTHTVPDAVGYILRTPEGTLIHTGDFKLD
PDPIDGLRTDLERWGEAGEEGVLCLLSDSTNSEVTEETGSERVVEQTFERLFQGATGRIIVALFSSNLHRVRHLLALAER
LGRKVALQGRSMLRNVEMAREMGYLDVPDSLFVHLDSVPALPAQRVLVLTTGAQGEPRAGLSQLASGDGPVRLNPGDLVV
LSSRAIPGNERSVGALIDALQWRGAKVAYAQVEPGIHVSGHASQPQQRRVLDLVRPAHFIPVHGEGRHLHKHLLTAREAG
LEPAQCLLAQDGDVVTFEEGRGRFTGSVPSGRILKDRFGPGLVTPDTLQERVRLSETGMVAAVVVLQRGSQQLVAGPQLS
GQGLSVDEQVLLPRVAQDARVLFEELSPILRGDDALVREELTRAVRRAFKAHTSKRALVVPLVVRV
>Mature_546_residues
MLHVIPLGGLGEIGLNSMVIACRGEMLLIDAGLMFPSAGMPGVDIIIPDFSHLKQNAAQLKGVLLTHGHEDHLGALPYLL
NEVPVPVYGTRFTLAMARHRLEELGIEADLREIEPREPFPVGTAFRVEASRVTHTVPDAVGYILRTPEGTLIHTGDFKLD
PDPIDGLRTDLERWGEAGEEGVLCLLSDSTNSEVTEETGSERVVEQTFERLFQGATGRIIVALFSSNLHRVRHLLALAER
LGRKVALQGRSMLRNVEMAREMGYLDVPDSLFVHLDSVPALPAQRVLVLTTGAQGEPRAGLSQLASGDGPVRLNPGDLVV
LSSRAIPGNERSVGALIDALQWRGAKVAYAQVEPGIHVSGHASQPQQRRVLDLVRPAHFIPVHGEGRHLHKHLLTAREAG
LEPAQCLLAQDGDVVTFEEGRGRFTGSVPSGRILKDRFGPGLVTPDTLQERVRLSETGMVAAVVVLQRGSQQLVAGPQLS
GQGLSVDEQVLLPRVAQDARVLFEELSPILRGDDALVREELTRAVRRAFKAHTSKRALVVPLVVRV

Specific function: Unknown

COG id: COG0595

COG function: function code R; Predicted hydrolase of the metallo-beta-lactamase superfamily

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. RNase J subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR011108
- InterPro:   IPR004613
- InterPro:   IPR001587 [H]

Pfam domain/function: PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 59281; Mature: 59281

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHVIPLGGLGEIGLNSMVIACRGEMLLIDAGLMFPSAGMPGVDIIIPDFSHLKQNAAQL
CEEEEECCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCCCEEEECCHHHHHHHHHHH
KGVLLTHGHEDHLGALPYLLNEVPVPVYGTRFTLAMARHRLEELGIEADLREIEPREPFP
CEEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCCCCC
VGTAFRVEASRVTHTVPDAVGYILRTPEGTLIHTGDFKLDPDPIDGLRTDLERWGEAGEE
CCCEEEEEHHHHHHHCHHHHHHEEECCCCCEEECCCCEECCCCCHHHHHHHHHHCCCCCC
GVLCLLSDSTNSEVTEETGSERVVEQTFERLFQGATGRIIVALFSSNLHRVRHLLALAER
CEEEEEECCCCCCHHHHCCHHHHHHHHHHHHHCCCCCEEEEEEHHCCHHHHHHHHHHHHH
LGRKVALQGRSMLRNVEMAREMGYLDVPDSLFVHLDSVPALPAQRVLVLTTGAQGEPRAG
HCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEECCCCCCCCCEEEEEEECCCCCCCCC
LSQLASGDGPVRLNPGDLVVLSSRAIPGNERSVGALIDALQWRGAKVAYAQVEPGIHVSG
HHHHHCCCCCEEECCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCEEECC
HASQPQQRRVLDLVRPAHFIPVHGEGRHLHKHLLTAREAGLEPAQCLLAQDGDVVTFEEG
CCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCHHHHHEECCCCEEEEECC
RGRFTGSVPSGRILKDRFGPGLVTPDTLQERVRLSETGMVAAVVVLQRGSQQLVAGPQLS
CCEEECCCCCCCEEHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEECCCCC
GQGLSVDEQVLLPRVAQDARVLFEELSPILRGDDALVREELTRAVRRAFKAHTSKRALVV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEE
PLVVRV
EEEEEC
>Mature Secondary Structure
MLHVIPLGGLGEIGLNSMVIACRGEMLLIDAGLMFPSAGMPGVDIIIPDFSHLKQNAAQL
CEEEEECCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCCCEEEECCHHHHHHHHHHH
KGVLLTHGHEDHLGALPYLLNEVPVPVYGTRFTLAMARHRLEELGIEADLREIEPREPFP
CEEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCCCCC
VGTAFRVEASRVTHTVPDAVGYILRTPEGTLIHTGDFKLDPDPIDGLRTDLERWGEAGEE
CCCEEEEEHHHHHHHCHHHHHHEEECCCCCEEECCCCEECCCCCHHHHHHHHHHCCCCCC
GVLCLLSDSTNSEVTEETGSERVVEQTFERLFQGATGRIIVALFSSNLHRVRHLLALAER
CEEEEEECCCCCCHHHHCCHHHHHHHHHHHHHCCCCCEEEEEEHHCCHHHHHHHHHHHHH
LGRKVALQGRSMLRNVEMAREMGYLDVPDSLFVHLDSVPALPAQRVLVLTTGAQGEPRAG
HCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEECCCCCCCCCEEEEEEECCCCCCCCC
LSQLASGDGPVRLNPGDLVVLSSRAIPGNERSVGALIDALQWRGAKVAYAQVEPGIHVSG
HHHHHCCCCCEEECCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCEEECC
HASQPQQRRVLDLVRPAHFIPVHGEGRHLHKHLLTAREAGLEPAQCLLAQDGDVVTFEEG
CCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCHHHHHEECCCCEEEEECC
RGRFTGSVPSGRILKDRFGPGLVTPDTLQERVRLSETGMVAAVVVLQRGSQQLVAGPQLS
CCEEECCCCCCCEEHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEECCCCC
GQGLSVDEQVLLPRVAQDARVLFEELSPILRGDDALVREELTRAVRRAFKAHTSKRALVV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEE
PLVVRV
EEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]