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The map label for this gene is 108758575

Identifier: 108758575

GI number: 108758575

Start: 705009

End: 706769

Strand: Direct

Name: 108758575

Synonym: MXAN_0610

Alternate gene names: NA

Gene position: 705009-706769 (Clockwise)

Preceding gene: 108762429

Following gene: 108757538

Centisome position: 7.71

GC content: 73.31

Gene sequence:

>1761_bases
ATGAGCCTGCGGGACTGGCTGTCGCGATGGCGTTGGGGCGGCGCGCCGGTGCCCGCCTTCTACGACGAGTCCTACCGGCT
GCCCCTCACCGGCATCGAGTCCTCCGCGGGCATCGAGCCGCGCGGCGTGGACTTCACCACCTGGTATCTCCTGGAGGCCC
GCGCGCTGCGCACCCAGGACGTGCACCACCCGCAGCCGGTGAGCCTCGCCGAGCTGTCGCGCGTGCATGACGCCGCCTAC
CTGGAGTCGCTCGGCCAGCCGGAGACGCTGGCGCGCATCTTCGCCACCGACCCCGCCGACGTGCCGGTGGACGCGCTGCT
GTCCAACCTGCGGCGGGTGTGCGGCGGCACGCTGGGCGCGGCGCGGCTCGCGGTGGCGCGCAAGGGCCCGGTGGTGAACA
TGGCGGGCGGCTTCCACCACGCCGGTCCGGCGCGCGGCGGCGGTTTCTGCGCGGTGAATGACATCGCGATAGCGCTCGCC
GCCCTCCACGCGGATGGCTTCGACGGACAGGCCGTGGTGCTCGACCTGGATGCCCACCCGCCGGATGGCACGGCGGAGTG
TCTGGCGGGACAGAAGCGGGCCTGGATTGGCTCGCTGTCCGGTAGCGACTGGGGCGCGTTGTCGCCCGAAGTGGATGAGA
CGCGCGTCCCCGAGGACACGGACGACAGGACGTATCTGGCCCTGCTCGACGGACTCCTGGAGCGCATGCCCCGGCCGGAC
GTGGCCTTCGTCATCGCGGGCAGCGACGTGCTCGCGGGAGACCGCTTCGGCCGCGTGGGCCTGTCCCTGGACGGCGCCCG
TCGCAGGGACCGGGCCCTGGCGCGCGCCCTGCGTGGCATCCCCAGCGTCTGGCTTCCAGGCGGGGGCTATCACCGCGACG
CGTGGAAGGTGTTCGCGGGCACCGTGCTCGTCCTCGCGGGTCAGGGCCGTCGCCGCATCAAGGCGCGTTATGACCCGCTG
AGCGCGCGGTATCGGCGCATCGCCCGCTCACTGACGCGCGAGGGCGCGACGCCGCTGGACGAGCCCATCACCCAGGAGGA
CCTGGAGGGTGCCCTCGGCCTGAGCGGCGGCCCGCGCCAGCCGCGCATCCTCGGCTACTACACGGCGCAGGCGCTCGAGT
ACGCCTTCTTCCGCTACGGAATCCTCTCCTACGTGGAGCGGCTCGGCTACAGCCGGCTGCGCGTGGAGGTGGGCTCCGTG
GGAGAGGGGGACCGGATGGAGGTGCACGGCTGCGCCGCGGGCCAGGAGCACCAGCTGGTGGACTGTGTCGTGGAGCGCCG
CGTGCTGGCGGGGGAGCCCTTCCTCTTCGTCAACTGGCTCAGCCTGCGCCACCCGCGCGCCCGCTTCAGCGAGGGGCGCT
CGCGGCTCCCCGGCCAGGACGTGCCGGGCCTGGGCCTGGCGCGCGAGGCGACGGAGATGCTGCTCGTGATGGCCCGGCGC
CTCGTCCTGGCGGGCGTGGCCTTCCGTCCCATGTGGTTCCACCTGGCGGTGCTGGCGCGCTCGCGCTTCCGTTTCCTCGA
CCCGGCGCGGCAGGGGCGCTTCGAGGCGCTGCTGCGCGACCTGGGGCAGCTGCCCCTCCTGGAGGTCTCCCAGGCGGTGG
TGGACGGCCACGTCCTGCTCAACGGTCAGCCCTACGCATGGGAGGCGAACGACATGGTGTCGCGCCTGGAGCCCGAGGCC
GGAGACTTGGAGGCCATTGCCCGGGAGCGCGAGCGCTGCCGCTTCACCTGGGAACCCGCCCGGCTGGCCACCGGAGCATG
A

Upstream 100 bases:

>100_bases
CCATGGCGCCGTTCACTGCGCGAAGCTCCAAGCTGCCGTGGTGCCTGGGCGTCCTGTGGGACCCTGGTCCCAGACCTGGC
GCCGTGAGAGACATGGGCCC

Downstream 100 bases:

>100_bases
TAGGGAAGGGGCGTGGACCTGGACGCGCTTCGCCGTGAGCAGCACAAGCGCCGGCTCTCCTGGATGCCGTGGCTCTACTT
CGTCCTCAAGCCCCGCCACC

Product: histone deacetylase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 586; Mature: 585

Protein sequence:

>586_residues
MSLRDWLSRWRWGGAPVPAFYDESYRLPLTGIESSAGIEPRGVDFTTWYLLEARALRTQDVHHPQPVSLAELSRVHDAAY
LESLGQPETLARIFATDPADVPVDALLSNLRRVCGGTLGAARLAVARKGPVVNMAGGFHHAGPARGGGFCAVNDIAIALA
ALHADGFDGQAVVLDLDAHPPDGTAECLAGQKRAWIGSLSGSDWGALSPEVDETRVPEDTDDRTYLALLDGLLERMPRPD
VAFVIAGSDVLAGDRFGRVGLSLDGARRRDRALARALRGIPSVWLPGGGYHRDAWKVFAGTVLVLAGQGRRRIKARYDPL
SARYRRIARSLTREGATPLDEPITQEDLEGALGLSGGPRQPRILGYYTAQALEYAFFRYGILSYVERLGYSRLRVEVGSV
GEGDRMEVHGCAAGQEHQLVDCVVERRVLAGEPFLFVNWLSLRHPRARFSEGRSRLPGQDVPGLGLAREATEMLLVMARR
LVLAGVAFRPMWFHLAVLARSRFRFLDPARQGRFEALLRDLGQLPLLEVSQAVVDGHVLLNGQPYAWEANDMVSRLEPEA
GDLEAIARERERCRFTWEPARLATGA

Sequences:

>Translated_586_residues
MSLRDWLSRWRWGGAPVPAFYDESYRLPLTGIESSAGIEPRGVDFTTWYLLEARALRTQDVHHPQPVSLAELSRVHDAAY
LESLGQPETLARIFATDPADVPVDALLSNLRRVCGGTLGAARLAVARKGPVVNMAGGFHHAGPARGGGFCAVNDIAIALA
ALHADGFDGQAVVLDLDAHPPDGTAECLAGQKRAWIGSLSGSDWGALSPEVDETRVPEDTDDRTYLALLDGLLERMPRPD
VAFVIAGSDVLAGDRFGRVGLSLDGARRRDRALARALRGIPSVWLPGGGYHRDAWKVFAGTVLVLAGQGRRRIKARYDPL
SARYRRIARSLTREGATPLDEPITQEDLEGALGLSGGPRQPRILGYYTAQALEYAFFRYGILSYVERLGYSRLRVEVGSV
GEGDRMEVHGCAAGQEHQLVDCVVERRVLAGEPFLFVNWLSLRHPRARFSEGRSRLPGQDVPGLGLAREATEMLLVMARR
LVLAGVAFRPMWFHLAVLARSRFRFLDPARQGRFEALLRDLGQLPLLEVSQAVVDGHVLLNGQPYAWEANDMVSRLEPEA
GDLEAIARERERCRFTWEPARLATGA
>Mature_585_residues
SLRDWLSRWRWGGAPVPAFYDESYRLPLTGIESSAGIEPRGVDFTTWYLLEARALRTQDVHHPQPVSLAELSRVHDAAYL
ESLGQPETLARIFATDPADVPVDALLSNLRRVCGGTLGAARLAVARKGPVVNMAGGFHHAGPARGGGFCAVNDIAIALAA
LHADGFDGQAVVLDLDAHPPDGTAECLAGQKRAWIGSLSGSDWGALSPEVDETRVPEDTDDRTYLALLDGLLERMPRPDV
AFVIAGSDVLAGDRFGRVGLSLDGARRRDRALARALRGIPSVWLPGGGYHRDAWKVFAGTVLVLAGQGRRRIKARYDPLS
ARYRRIARSLTREGATPLDEPITQEDLEGALGLSGGPRQPRILGYYTAQALEYAFFRYGILSYVERLGYSRLRVEVGSVG
EGDRMEVHGCAAGQEHQLVDCVVERRVLAGEPFLFVNWLSLRHPRARFSEGRSRLPGQDVPGLGLAREATEMLLVMARRL
VLAGVAFRPMWFHLAVLARSRFRFLDPARQGRFEALLRDLGQLPLLEVSQAVVDGHVLLNGQPYAWEANDMVSRLEPEAG
DLEAIARERERCRFTWEPARLATGA

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI217272877, Length=309, Percent_Identity=29.7734627831715, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI209862883, Length=216, Percent_Identity=33.7962962962963, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI13128860, Length=336, Percent_Identity=24.4047619047619, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI293336691, Length=255, Percent_Identity=24.7058823529412, Blast_Score=81, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI193207430, Length=344, Percent_Identity=29.9418604651163, Blast_Score=112, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17508561, Length=278, Percent_Identity=27.6978417266187, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17561978, Length=280, Percent_Identity=26.0714285714286, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17537347, Length=313, Percent_Identity=27.7955271565495, Blast_Score=73, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17534739, Length=267, Percent_Identity=29.2134831460674, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323999, Length=281, Percent_Identity=25.6227758007117, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24649807, Length=317, Percent_Identity=27.7602523659306, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24657891, Length=280, Percent_Identity=23.2142857142857, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 64293; Mature: 64162

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRDWLSRWRWGGAPVPAFYDESYRLPLTGIESSAGIEPRGVDFTTWYLLEARALRTQD
CCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHCC
VHHPQPVSLAELSRVHDAAYLESLGQPETLARIFATDPADVPVDALLSNLRRVCGGTLGA
CCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHH
ARLAVARKGPVVNMAGGFHHAGPARGGGFCAVNDIAIALAALHADGFDGQAVVLDLDAHP
HHHHHHCCCCEEEECCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCCEEEEEECCCC
PDGTAECLAGQKRAWIGSLSGSDWGALSPEVDETRVPEDTDDRTYLALLDGLLERMPRPD
CCCHHHHHCCCCHHEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCC
VAFVIAGSDVLAGDRFGRVGLSLDGARRRDRALARALRGIPSVWLPGGGYHRDAWKVFAG
EEEEEECCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHC
TVLVLAGQGRRRIKARYDPLSARYRRIARSLTREGATPLDEPITQEDLEGALGLSGGPRQ
EEEEEECCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCC
PRILGYYTAQALEYAFFRYGILSYVERLGYSRLRVEVGSVGEGDRMEVHGCAAGQEHQLV
CEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEECCCCCCCHHH
DCVVERRVLAGEPFLFVNWLSLRHPRARFSEGRSRLPGQDVPGLGLAREATEMLLVMARR
HHHHHHHHHCCCCEEEEEHHHHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
LVLAGVAFRPMWFHLAVLARSRFRFLDPARQGRFEALLRDLGQLPLLEVSQAVVDGHVLL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHCCCCHHHHHHHHHCCEEEE
NGQPYAWEANDMVSRLEPEAGDLEAIARERERCRFTWEPARLATGA
CCCCCEECHHHHHHHCCCCCCHHHHHHHHHHHCCEEECCHHHCCCC
>Mature Secondary Structure 
SLRDWLSRWRWGGAPVPAFYDESYRLPLTGIESSAGIEPRGVDFTTWYLLEARALRTQD
CHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHCC
VHHPQPVSLAELSRVHDAAYLESLGQPETLARIFATDPADVPVDALLSNLRRVCGGTLGA
CCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHH
ARLAVARKGPVVNMAGGFHHAGPARGGGFCAVNDIAIALAALHADGFDGQAVVLDLDAHP
HHHHHHCCCCEEEECCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCCEEEEEECCCC
PDGTAECLAGQKRAWIGSLSGSDWGALSPEVDETRVPEDTDDRTYLALLDGLLERMPRPD
CCCHHHHHCCCCHHEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCC
VAFVIAGSDVLAGDRFGRVGLSLDGARRRDRALARALRGIPSVWLPGGGYHRDAWKVFAG
EEEEEECCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHC
TVLVLAGQGRRRIKARYDPLSARYRRIARSLTREGATPLDEPITQEDLEGALGLSGGPRQ
EEEEEECCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCC
PRILGYYTAQALEYAFFRYGILSYVERLGYSRLRVEVGSVGEGDRMEVHGCAAGQEHQLV
CEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEECCCCCCCHHH
DCVVERRVLAGEPFLFVNWLSLRHPRARFSEGRSRLPGQDVPGLGLAREATEMLLVMARR
HHHHHHHHHCCCCEEEEEHHHHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
LVLAGVAFRPMWFHLAVLARSRFRFLDPARQGRFEALLRDLGQLPLLEVSQAVVDGHVLL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHCCCCHHHHHHHHHCCEEEE
NGQPYAWEANDMVSRLEPEAGDLEAIARERERCRFTWEPARLATGA
CCCCCEECHHHHHHHCCCCCCHHHHHHHHHHHCCEEECCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7678591 [H]