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The map label for this gene is qorA [H]

Identifier: 108758562

GI number: 108758562

Start: 269920

End: 270957

Strand: Direct

Name: qorA [H]

Synonym: MXAN_0222

Alternate gene names: 108758562

Gene position: 269920-270957 (Clockwise)

Preceding gene: 108761042

Following gene: 108763218

Centisome position: 2.95

GC content: 67.44

Gene sequence:

>1038_bases
ATGCGCGCACGCAAGGTCGTCATCCGGAAAGCAGGTGGGTACGAGCAGCTCCACCTTGAAGAGGTGAATCAGGATTCACC
TGGAATCGGTGAGGTCCGGGTGGCCACCGAAGCCATTGGGGTGAACTATGCGGACTGCGTCATCCGCATGGGGCTGTACG
CCTCCGCGAAGGAATATGTGGGGTGGCCCATCACCCCGGGCTTCGAGTTCGCGGGCCACGTGGATGCCGTGGGACCAGGC
GTGGAAGACCTGGCACCCGGAGCGCGGGTGTTCGGCGTGACGCGCTTCGGTGGTTACGCCACCCACGTCACGGTGCCCCG
TCACCAGGTGTTCACATTGCCCGCGCGGCTGAGCATGGAGCAGGCCGCGGGGTTCCCCACGGTGTTCCTCACCGCGTACT
ACGCGCTGTTCGAACTGGCGCATCCGCGTCCGGGGGCCAACGTGCTGGTGCACTCGGCGGCGGGGGGCGTGGGTGGGGCG
TTGCTCCAGTTGGGCCGCATCGCCGGGTGCCGGATGGTGGGCGTGGTGGGCGGGACGCACAAGGTGGAGACGGCCCGCGC
GCAGGGGGCGGAGGTCGTCATCGACAAGAGTCGGGAGGACTTGTGGAGCGTGGCCAAGAAGGCGGCGCCCCGTGGTTATG
ACGTGGTGCTGGATGCGAACGGGCCGTCCACGTTGCGCGACAGCTACAAGCACCTGGCGTCGCCGGGGAAGCTCGTCATC
TACGGCTTCCACTCCATGCTGCCGCGCACCGGTGGGCGGCCGAACTACGCGAAGCTGGCCTGGGACTGGCTGCGCACGCC
GCGGTTCGATCCGCTGACGCTCACCAACGACAACACCAGCGTGCTGGCGTTCAACCTGTCGTACCTGTTCGAGCAGCGCG
CCGTATTGGAGGAGTCCATGGCGCAGCTCTTGGGCTGGTTGGAGGAGGGGAAGCTGGTGCCGCCACCGGTGAAGTCGTTT
CCGTTGGACGCGGTGGCGGATGCGCACCGGGCACTGGAGTCCGGCGGCACGGTGGGGAAGCTGGTGTTGGTGCCGTGA

Upstream 100 bases:

>100_bases
GAATTCGATACACAGTCTAGAGACATCTCGCGCGCGCGTCTTCCGCTGACTGGACGTGCGCGGACGTTGTCGCGTTGCGT
CGCGTGGTAAGCAACGCGCC

Downstream 100 bases:

>100_bases
ATGCGTGCTTCAGAGGGGGAGCTGCGCGCCCTGCAGGGTGAGGAGGCTCTGCGGGACGACCCATGCCGCCTCCGGGTCGG
AGAGCACGCCGAGGTACGCG

Product: zinc-binding dehydrogenase family oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MRARKVVIRKAGGYEQLHLEEVNQDSPGIGEVRVATEAIGVNYADCVIRMGLYASAKEYVGWPITPGFEFAGHVDAVGPG
VEDLAPGARVFGVTRFGGYATHVTVPRHQVFTLPARLSMEQAAGFPTVFLTAYYALFELAHPRPGANVLVHSAAGGVGGA
LLQLGRIAGCRMVGVVGGTHKVETARAQGAEVVIDKSREDLWSVAKKAAPRGYDVVLDANGPSTLRDSYKHLASPGKLVI
YGFHSMLPRTGGRPNYAKLAWDWLRTPRFDPLTLTNDNTSVLAFNLSYLFEQRAVLEESMAQLLGWLEEGKLVPPPVKSF
PLDAVADAHRALESGGTVGKLVLVP

Sequences:

>Translated_345_residues
MRARKVVIRKAGGYEQLHLEEVNQDSPGIGEVRVATEAIGVNYADCVIRMGLYASAKEYVGWPITPGFEFAGHVDAVGPG
VEDLAPGARVFGVTRFGGYATHVTVPRHQVFTLPARLSMEQAAGFPTVFLTAYYALFELAHPRPGANVLVHSAAGGVGGA
LLQLGRIAGCRMVGVVGGTHKVETARAQGAEVVIDKSREDLWSVAKKAAPRGYDVVLDANGPSTLRDSYKHLASPGKLVI
YGFHSMLPRTGGRPNYAKLAWDWLRTPRFDPLTLTNDNTSVLAFNLSYLFEQRAVLEESMAQLLGWLEEGKLVPPPVKSF
PLDAVADAHRALESGGTVGKLVLVP
>Mature_345_residues
MRARKVVIRKAGGYEQLHLEEVNQDSPGIGEVRVATEAIGVNYADCVIRMGLYASAKEYVGWPITPGFEFAGHVDAVGPG
VEDLAPGARVFGVTRFGGYATHVTVPRHQVFTLPARLSMEQAAGFPTVFLTAYYALFELAHPRPGANVLVHSAAGGVGGA
LLQLGRIAGCRMVGVVGGTHKVETARAQGAEVVIDKSREDLWSVAKKAAPRGYDVVLDANGPSTLRDSYKHLASPGKLVI
YGFHSMLPRTGGRPNYAKLAWDWLRTPRFDPLTLTNDNTSVLAFNLSYLFEQRAVLEESMAQLLGWLEEGKLVPPPVKSF
PLDAVADAHRALESGGTVGKLVLVP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI18379349, Length=344, Percent_Identity=35.4651162790698, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI24308257, Length=343, Percent_Identity=31.4868804664723, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI22538446, Length=338, Percent_Identity=30.1775147928994, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI22538444, Length=338, Percent_Identity=30.1775147928994, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI194239674, Length=345, Percent_Identity=27.536231884058, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI13236495, Length=345, Percent_Identity=27.536231884058, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI194239676, Length=344, Percent_Identity=26.453488372093, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI41872631, Length=286, Percent_Identity=27.2727272727273, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI226059159, Length=140, Percent_Identity=35, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI226059133, Length=140, Percent_Identity=35, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI226056130, Length=140, Percent_Identity=35, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI28557745, Length=329, Percent_Identity=26.4437689969605, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1790485, Length=349, Percent_Identity=30.3724928366762, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI226510941, Length=117, Percent_Identity=30.7692307692308, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=241, Percent_Identity=32.7800829875519, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI212642053, Length=292, Percent_Identity=25, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=348, Percent_Identity=29.0229885057471, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24581345, Length=330, Percent_Identity=23.9393939393939, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI19920632, Length=312, Percent_Identity=23.7179487179487, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI221330659, Length=312, Percent_Identity=23.7179487179487, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 37096; Mature: 37096

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRARKVVIRKAGGYEQLHLEEVNQDSPGIGEVRVATEAIGVNYADCVIRMGLYASAKEYV
CCCCEEEEEECCCCCEEEHHHCCCCCCCCCEEEEEHHHHCCCHHHHHHHHHHHHCHHHHC
GWPITPGFEFAGHVDAVGPGVEDLAPGARVFGVTRFGGYATHVTVPRHQVFTLPARLSME
CCCCCCCCCCCCCCCCCCCCHHHHCCCCCEEEEEECCCEEEEEECCCCEEEECCHHHCHH
QAAGFPTVFLTAYYALFELAHPRPGANVLVHSAAGGVGGALLQLGRIAGCRMVGVVGGTH
HHCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCC
KVETARAQGAEVVIDKSREDLWSVAKKAAPRGYDVVLDANGPSTLRDSYKHLASPGKLVI
EEHHHHCCCCEEEEECCHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEE
YGFHSMLPRTGGRPNYAKLAWDWLRTPRFDPLTLTNDNTSVLAFNLSYLFEQRAVLEESM
EECHHHCCCCCCCCCHHHHHHHHHCCCCCCCEEEECCCCEEEEEEHHHHHHHHHHHHHHH
AQLLGWLEEGKLVPPPVKSFPLDAVADAHRALESGGTVGKLVLVP
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEC
>Mature Secondary Structure
MRARKVVIRKAGGYEQLHLEEVNQDSPGIGEVRVATEAIGVNYADCVIRMGLYASAKEYV
CCCCEEEEEECCCCCEEEHHHCCCCCCCCCEEEEEHHHHCCCHHHHHHHHHHHHCHHHHC
GWPITPGFEFAGHVDAVGPGVEDLAPGARVFGVTRFGGYATHVTVPRHQVFTLPARLSME
CCCCCCCCCCCCCCCCCCCCHHHHCCCCCEEEEEECCCEEEEEECCCCEEEECCHHHCHH
QAAGFPTVFLTAYYALFELAHPRPGANVLVHSAAGGVGGALLQLGRIAGCRMVGVVGGTH
HHCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCC
KVETARAQGAEVVIDKSREDLWSVAKKAAPRGYDVVLDANGPSTLRDSYKHLASPGKLVI
EEHHHHCCCCEEEEECCHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEE
YGFHSMLPRTGGRPNYAKLAWDWLRTPRFDPLTLTNDNTSVLAFNLSYLFEQRAVLEESM
EECHHHCCCCCCCCCHHHHHHHHHCCCCCCCEEEECCCCEEEEEEHHHHHHHHHHHHHHH
AQLLGWLEEGKLVPPPVKSFPLDAVADAHRALESGGTVGKLVLVP
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]