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The map label for this gene is ruvB

Identifier: 108758416

GI number: 108758416

Start: 6215180

End: 6216211

Strand: Reverse

Name: ruvB

Synonym: MXAN_4969

Alternate gene names: 108758416

Gene position: 6216211-6215180 (Counterclockwise)

Preceding gene: 108762446

Following gene: 108763192

Centisome position: 68.01

GC content: 67.25

Gene sequence:

>1032_bases
ATGGTCATGGCGAGGAAGTCCGACACACTCTCGGAAGACGTCCTGCCCGAGGACGTCCGGCTCGAGGCTTCCCTGCGTCC
GCGCTCGTTCGACGAGTACGTGGGCCAGGGGCCCGTCGTCGAAAAGCTCAAGGTCTACGTGCAGGCCGCGCGCAGCCGGG
GCGAAGCCCTGGACCACTGCCTGTTCTCCGGCCCGCCGGGCCTGGGCAAGACGTCGCTGGCGCACATCATCGCGAACGAA
CTGGGCGTGGGAATCCACGTCACGAGCGGCCCCGCCCTGGAGCGCAAGGGGGACCTCGCGGGCCTGCTCACCAACCTCGA
CGCGCGGGACGTGCTCTTCATCGATGAAATCCACCGCCTCAACGCCGCCGTGGAGGAATACCTCTACCCGGCCATGGAGG
ACTTCCGGCTGGACATCACCATCGACACCGGGCCCGCCGCCCGGGCGATGAAGATTGATTTGCCGCCCTTCACGTTGATT
GGCGCCACCACGCGCACCGGCCTGCTCACCTCGCCGCTGCGCGACCGCTTCCAGATTCAGGAACGGCTGGAGTACTACGA
CGCCAAGGCGCTGGAGAGCATCCTCCACCGCTCCGCGCGCATCCTGGGCATTCCCCTGGACAAGGACGCCGCGCGCGAGG
TGGCCAGCCGTTCGCGGGGCACGCCGCGCATCACCAACCGGCTGCTGCGCCGGCTGCGTGATTTCGCGGAGGTGGAAGGC
AATGGCAGAATCACCCTGGAGCTGGCGCAGAAGTCGCTGGACAGGCTCGGGGTGGACGCCAGCGGCCTGGACTCCATGGA
CCGCAAGATTCTGCTGACCATTCTCGACAAGTTCGGCGGCGGCCCGGTGGGTGTGGAGACCATCGCCGCCAGCGTGGGCG
AGCAGCGCGATACCATCGAGGACGTGTACGAGCCCTTCCTGATGCAGGAAGGCTTCCTCCAGCGTACGCCGCGGGGCCGG
ATGGCCACGCACCGCACGTACCAATATTTCAAGAAGCAACCACCGCCCACGCCCCAGGGCAGCCTCTTCTGA

Upstream 100 bases:

>100_bases
CCCCTGCCCGCGCCCGCCTGGCTGGCAGGGCCGGCGGCCGTCTGGATGTATCGCCGCCAGATGTGCGGCGACACGCGCGG
CCTTCCTGTATAGGGTCCGG

Downstream 100 bases:

>100_bases
GATGCCATGAGCCAGGACACGCCTTCCTCACCGCCCCGCGTCCCCCGCGACTTCTACGCCGACCTGATGCGCGCTTCCCA
GACGTCGCGCGCCGGCTTCC

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MVMARKSDTLSEDVLPEDVRLEASLRPRSFDEYVGQGPVVEKLKVYVQAARSRGEALDHCLFSGPPGLGKTSLAHIIANE
LGVGIHVTSGPALERKGDLAGLLTNLDARDVLFIDEIHRLNAAVEEYLYPAMEDFRLDITIDTGPAARAMKIDLPPFTLI
GATTRTGLLTSPLRDRFQIQERLEYYDAKALESILHRSARILGIPLDKDAAREVASRSRGTPRITNRLLRRLRDFAEVEG
NGRITLELAQKSLDRLGVDASGLDSMDRKILLTILDKFGGGPVGVETIAASVGEQRDTIEDVYEPFLMQEGFLQRTPRGR
MATHRTYQYFKKQPPPTPQGSLF

Sequences:

>Translated_343_residues
MVMARKSDTLSEDVLPEDVRLEASLRPRSFDEYVGQGPVVEKLKVYVQAARSRGEALDHCLFSGPPGLGKTSLAHIIANE
LGVGIHVTSGPALERKGDLAGLLTNLDARDVLFIDEIHRLNAAVEEYLYPAMEDFRLDITIDTGPAARAMKIDLPPFTLI
GATTRTGLLTSPLRDRFQIQERLEYYDAKALESILHRSARILGIPLDKDAAREVASRSRGTPRITNRLLRRLRDFAEVEG
NGRITLELAQKSLDRLGVDASGLDSMDRKILLTILDKFGGGPVGVETIAASVGEQRDTIEDVYEPFLMQEGFLQRTPRGR
MATHRTYQYFKKQPPPTPQGSLF
>Mature_343_residues
MVMARKSDTLSEDVLPEDVRLEASLRPRSFDEYVGQGPVVEKLKVYVQAARSRGEALDHCLFSGPPGLGKTSLAHIIANE
LGVGIHVTSGPALERKGDLAGLLTNLDARDVLFIDEIHRLNAAVEEYLYPAMEDFRLDITIDTGPAARAMKIDLPPFTLI
GATTRTGLLTSPLRDRFQIQERLEYYDAKALESILHRSARILGIPLDKDAAREVASRSRGTPRITNRLLRRLRDFAEVEG
NGRITLELAQKSLDRLGVDASGLDSMDRKILLTILDKFGGGPVGVETIAASVGEQRDTIEDVYEPFLMQEGFLQRTPRGR
MATHRTYQYFKKQPPPTPQGSLF

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=324, Percent_Identity=61.7283950617284, Blast_Score=416, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_MYXXD (Q1D2J8)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_633125.1
- ProteinModelPortal:   Q1D2J8
- SMR:   Q1D2J8
- STRING:   Q1D2J8
- GeneID:   4104735
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_4969
- TIGR:   MXAN_4969
- eggNOG:   COG2255
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- PhylomeDB:   Q1D2J8
- ProtClustDB:   PRK00080
- BioCyc:   MXAN246197:MXAN_4969-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 38065; Mature: 38065

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMARKSDTLSEDVLPEDVRLEASLRPRSFDEYVGQGPVVEKLKVYVQAARSRGEALDHC
CCCCCCCCCCHHHCCCCCCEEECCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LFSGPPGLGKTSLAHIIANELGVGIHVTSGPALERKGDLAGLLTNLDARDVLFIDEIHRL
HHCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHH
NAAVEEYLYPAMEDFRLDITIDTGPAARAMKIDLPPFTLIGATTRTGLLTSPLRDRFQIQ
HHHHHHHHHHCHHCCEEEEEEECCCCCCEEEECCCCEEEEECCHHCCCHHHHHHHHHHHH
ERLEYYDAKALESILHRSARILGIPLDKDAAREVASRSRGTPRITNRLLRRLRDFAEVEG
HHHHHHHHHHHHHHHHCCHHEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
NGRITLELAQKSLDRLGVDASGLDSMDRKILLTILDKFGGGPVGVETIAASVGEQRDTIE
CCEEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHH
DVYEPFLMQEGFLQRTPRGRMATHRTYQYFKKQPPPTPQGSLF
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MVMARKSDTLSEDVLPEDVRLEASLRPRSFDEYVGQGPVVEKLKVYVQAARSRGEALDHC
CCCCCCCCCCHHHCCCCCCEEECCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LFSGPPGLGKTSLAHIIANELGVGIHVTSGPALERKGDLAGLLTNLDARDVLFIDEIHRL
HHCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHH
NAAVEEYLYPAMEDFRLDITIDTGPAARAMKIDLPPFTLIGATTRTGLLTSPLRDRFQIQ
HHHHHHHHHHCHHCCEEEEEEECCCCCCEEEECCCCEEEEECCHHCCCHHHHHHHHHHHH
ERLEYYDAKALESILHRSARILGIPLDKDAAREVASRSRGTPRITNRLLRRLRDFAEVEG
HHHHHHHHHHHHHHHHCCHHEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
NGRITLELAQKSLDRLGVDASGLDSMDRKILLTILDKFGGGPVGVETIAASVGEQRDTIE
CCEEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHH
DVYEPFLMQEGFLQRTPRGRMATHRTYQYFKKQPPPTPQGSLF
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA