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The map label for this gene is ung [H]

Identifier: 108758158

GI number: 108758158

Start: 869122

End: 869799

Strand: Direct

Name: ung [H]

Synonym: MXAN_0760

Alternate gene names: 108758158

Gene position: 869122-869799 (Clockwise)

Preceding gene: 108761781

Following gene: 108757426

Centisome position: 9.51

GC content: 68.58

Gene sequence:

>678_bases
GTGCTCGCGGAAGGGCTGCCGGAAGACTGGAAGCAGGAGCTGCGCGCGGCGTTGGCGTCGCCGTCGTTCCATGAGCTGGA
GCGCTTCGTCGAAGCGGAGCGGCGGGAGGCCACCGTCTTTCCGTCGGAGGAGGACCTCTTCTCCGCCTTCCGGCTCACGC
CCTATGAAGACGTGCGGGTGTTGCTGCTGGGCCAGGACCCCTACCACGGGCCGGGACAGGCGCATGGGCTGGCCTTCTCG
GTGAAGCCGGGGGTGGCGCCGCCGCCCTCGCTGGTTAACATGTTCAAGGAGCTGGAGAGCGACGTGGGCGTGCCCCGCCC
GAAGGACGGCTCTCTGATTCCCTGGGCCCGGCAGGGTGTGCTGCTGCTCAACGCGGTGCTGACGGTGCGGCAGGCGAAGC
CCAACAGCCACGCGGGGCACGGCTGGGAGGACTTCACGGACGCCGTCATTCGCGCGGTGAGCGCCAAGGACGACCCGGTG
GTGTTCCTGCTGTGGGGCCGCTACGCGCAGAAGAAGAAGAAGCTCATCGATTCGAAGCGGCACGTCGTCATCGAGGGCAC
ACACCCCTCGCCGCTGTCGGCCAGCAATGGCTTCTTCGGCAGCCGTCCCTTCAGCGCCGTGAATGAGGCGCTGGAGTCCC
ACGGCCGTCCGCCCATCGACTGGCGCCTGTCCGCCTGA

Upstream 100 bases:

>100_bases
CCGCCCACCGGCGGTTTCCAGCGTGGCCGGGCGGAAAAGCAGTGGGCGCTCCCGATGCCCGGTGTTTCAATGCCGCCGCC
GTCGGAAAAGGGAGGCGTTC

Downstream 100 bases:

>100_bases
AGGGGCGGCGAGCCGCGAGAGACTCGGGCCGGACACACCGGGGCCGCGTTGATACGCTGCGGCGCGACATGACCGCTGCC
TTCCTCGCTGCCACCACCCC

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: UDG [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MLAEGLPEDWKQELRAALASPSFHELERFVEAERREATVFPSEEDLFSAFRLTPYEDVRVLLLGQDPYHGPGQAHGLAFS
VKPGVAPPPSLVNMFKELESDVGVPRPKDGSLIPWARQGVLLLNAVLTVRQAKPNSHAGHGWEDFTDAVIRAVSAKDDPV
VFLLWGRYAQKKKKLIDSKRHVVIEGTHPSPLSASNGFFGSRPFSAVNEALESHGRPPIDWRLSA

Sequences:

>Translated_225_residues
MLAEGLPEDWKQELRAALASPSFHELERFVEAERREATVFPSEEDLFSAFRLTPYEDVRVLLLGQDPYHGPGQAHGLAFS
VKPGVAPPPSLVNMFKELESDVGVPRPKDGSLIPWARQGVLLLNAVLTVRQAKPNSHAGHGWEDFTDAVIRAVSAKDDPV
VFLLWGRYAQKKKKLIDSKRHVVIEGTHPSPLSASNGFFGSRPFSAVNEALESHGRPPIDWRLSA
>Mature_225_residues
MLAEGLPEDWKQELRAALASPSFHELERFVEAERREATVFPSEEDLFSAFRLTPYEDVRVLLLGQDPYHGPGQAHGLAFS
VKPGVAPPPSLVNMFKELESDVGVPRPKDGSLIPWARQGVLLLNAVLTVRQAKPNSHAGHGWEDFTDAVIRAVSAKDDPV
VFLLWGRYAQKKKKLIDSKRHVVIEGTHPSPLSASNGFFGSRPFSAVNEALESHGRPPIDWRLSA

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine [H]

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family [H]

Homologues:

Organism=Homo sapiens, GI19718751, Length=219, Percent_Identity=52.0547945205479, Blast_Score=231, Evalue=4e-61,
Organism=Homo sapiens, GI6224979, Length=219, Percent_Identity=52.0547945205479, Blast_Score=231, Evalue=4e-61,
Organism=Escherichia coli, GI1788934, Length=214, Percent_Identity=54.6728971962617, Blast_Score=235, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI17556304, Length=217, Percent_Identity=49.7695852534562, Blast_Score=224, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6323620, Length=237, Percent_Identity=43.8818565400844, Blast_Score=182, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: =3.2.2.27 [H]

Molecular weight: Translated: 24889; Mature: 24889

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAEGLPEDWKQELRAALASPSFHELERFVEAERREATVFPSEEDLFSAFRLTPYEDVRV
CCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHCEEE
LLLGQDPYHGPGQAHGLAFSVKPGVAPPPSLVNMFKELESDVGVPRPKDGSLIPWARQGV
EEECCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCH
LLLNAVLTVRQAKPNSHAGHGWEDFTDAVIRAVSAKDDPVVFLLWGRYAQKKKKLIDSKR
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHCCCC
HVVIEGTHPSPLSASNGFFGSRPFSAVNEALESHGRPPIDWRLSA
EEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEECC
>Mature Secondary Structure
MLAEGLPEDWKQELRAALASPSFHELERFVEAERREATVFPSEEDLFSAFRLTPYEDVRV
CCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHCEEE
LLLGQDPYHGPGQAHGLAFSVKPGVAPPPSLVNMFKELESDVGVPRPKDGSLIPWARQGV
EEECCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCH
LLLNAVLTVRQAKPNSHAGHGWEDFTDAVIRAVSAKDDPVVFLLWGRYAQKKKKLIDSKR
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHCCCC
HVVIEGTHPSPLSASNGFFGSRPFSAVNEALESHGRPPIDWRLSA
EEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA