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The map label for this gene is frzCD

Identifier: 108758065

GI number: 108758065

Start: 5088451

End: 5089704

Strand: Reverse

Name: frzCD

Synonym: MXAN_4141

Alternate gene names: 108758065

Gene position: 5089704-5088451 (Counterclockwise)

Preceding gene: 108762907

Following gene: 108760926

Centisome position: 55.69

GC content: 70.57

Gene sequence:

>1254_bases
ATGTCCCTGGACACCCCCAACGAGAAGCCCGCTGGCAAGGCTCGCGCCCGGAAGGCCCCCGCCTCCAAGGCCGGCGCCAC
GAACGCGGCGTCGACCTCTTCCTCCACCAAGGCCATCACCGACACGCTGCTGACGGTGCTGTCCGGCAACCTGCAGGCCC
GCGTGCCCAAGGAGCTGGTCGGTGAGTCCGGCGTGGAGCTGGCGCACCTGCTCAACCAGGTGCTGGACCAGTTCGCGGCC
TCCGAGCACCGCAAGCATGTGGCGGCGCAGGAGATCGACCAGGCGTTGGATGCGCTCATCGGCCTGGTGCGCGAGGGCGA
CCTGTCCCGGTGGAACACCACCACCGAAGACCCGCAGCTCGGGCCCCTGCTGGAGGGCTTTGGCAAGGTCATCGAGACGC
TGCGCACCTTCGTGCGGGAGATCAACGAGGCGGCGTTGAGGCTGTCCTCGTCCGCCAACCAGGTGCTGGCGGCCTCCACG
CAGCATGAGACGTCCTCCACGGAGCAGGCGGCGGCCATCCACGAGACGACCGCCACCATGGAGGAGCTGAAGCACGCGTC
GGCGCAGATCGCCGAGAACGCGGGCAGCGTGGCGCGCGTGGCGGAAGAGACGCTGGGCGCGGCGCGCGCGGGCCGGGGCG
CCATTGGCGAGTTCATCCAGGCCATGCAGCAGATCCGCAGCGACGGCGTCGCGGTGGCGGACTCCATCGCGAAGCTGTCC
AAGCGCGTGGAGCGCATCGGCACGGTGGTGGAGGTCATCGACGAGATCGCGGACCGCTCCGACCTGCTGGCGCTGAACGC
GGCGCTGGAAGGCAGCCGCGCGGGTGAGGCCGGCAAGGGCTTCTCCATCGTCGCGGCGGAGATGCGGCGTCTGGCGGAGA
ACGTCCTGGACTCCACCAAGGAGATCAAGAACCTCATCACCGAGATTCGCGAGGCCACGGCCGCCGCGGCCGGCGCCGCC
GAGGCGTCCAAGTCCGCCACGGAGTCTGGTGAGAAGCTGGGCGCGGTGGCGGCGCAGGCGGTGGAAGGCATCCTCGCCGG
CGTCCAGGAGACGAGCGACGCGGCCCGCGTCATCAACCTCGCCACGCAGCAGCAGCGCACGGCCACCGAGCAGGTGGTGG
CCTCCATGGCGGAGATCGAGGACGTGACGCGCCAGACGACGCAGGCCTCGAAGCAGGCCACGGGCGCGGCCGCGGAGCTG
ACGCAGTTGGCCGGACGGCTGGCCGAGCTCATCAAGCGGTTCAAGGCCGACTAG

Upstream 100 bases:

>100_bases
CCGCAGCCTACGCAGTCGGTGTGTGCCTGGAAGAGGCCCGCACCGTGTTGCTCATCGATCTGGTCGAAACCGCAAGGACT
CAAGGAAGGCACTGAGACAC

Downstream 100 bases:

>100_bases
CGCTTCCTGGAAGGGGAGGGGCGTACGCCGGCCATGGACACCGAGGCTCTCAAGAAATCCCTCCTGAAGAAGTTCCAGGA
GGTCACCGCCGACCGCCTCC

Product: frizzy aggregation protein FrzCD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MSLDTPNEKPAGKARARKAPASKAGATNAASTSSSTKAITDTLLTVLSGNLQARVPKELVGESGVELAHLLNQVLDQFAA
SEHRKHVAAQEIDQALDALIGLVREGDLSRWNTTTEDPQLGPLLEGFGKVIETLRTFVREINEAALRLSSSANQVLAAST
QHETSSTEQAAAIHETTATMEELKHASAQIAENAGSVARVAEETLGAARAGRGAIGEFIQAMQQIRSDGVAVADSIAKLS
KRVERIGTVVEVIDEIADRSDLLALNAALEGSRAGEAGKGFSIVAAEMRRLAENVLDSTKEIKNLITEIREATAAAAGAA
EASKSATESGEKLGAVAAQAVEGILAGVQETSDAARVINLATQQQRTATEQVVASMAEIEDVTRQTTQASKQATGAAAEL
TQLAGRLAELIKRFKAD

Sequences:

>Translated_417_residues
MSLDTPNEKPAGKARARKAPASKAGATNAASTSSSTKAITDTLLTVLSGNLQARVPKELVGESGVELAHLLNQVLDQFAA
SEHRKHVAAQEIDQALDALIGLVREGDLSRWNTTTEDPQLGPLLEGFGKVIETLRTFVREINEAALRLSSSANQVLAAST
QHETSSTEQAAAIHETTATMEELKHASAQIAENAGSVARVAEETLGAARAGRGAIGEFIQAMQQIRSDGVAVADSIAKLS
KRVERIGTVVEVIDEIADRSDLLALNAALEGSRAGEAGKGFSIVAAEMRRLAENVLDSTKEIKNLITEIREATAAAAGAA
EASKSATESGEKLGAVAAQAVEGILAGVQETSDAARVINLATQQQRTATEQVVASMAEIEDVTRQTTQASKQATGAAAEL
TQLAGRLAELIKRFKAD
>Mature_416_residues
SLDTPNEKPAGKARARKAPASKAGATNAASTSSSTKAITDTLLTVLSGNLQARVPKELVGESGVELAHLLNQVLDQFAAS
EHRKHVAAQEIDQALDALIGLVREGDLSRWNTTTEDPQLGPLLEGFGKVIETLRTFVREINEAALRLSSSANQVLAASTQ
HETSSTEQAAAIHETTATMEELKHASAQIAENAGSVARVAEETLGAARAGRGAIGEFIQAMQQIRSDGVAVADSIAKLSK
RVERIGTVVEVIDEIADRSDLLALNAALEGSRAGEAGKGFSIVAAEMRRLAENVLDSTKEIKNLITEIREATAAAAGAAE
ASKSATESGEKLGAVAAQAVEGILAGVQETSDAARVINLATQQQRTATEQVVASMAEIEDVTRQTTQASKQATGAAAELT
QLAGRLAELIKRFKAD

Specific function: Methyl-accepting taxis protein necessary for the proper aggregation of cells to form fruiting bodies. Frz genes define a system of signal transduction analogous to the enterobacterial chemotaxis systems

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain

Homologues:

Organism=Escherichia coli, GI1788195, Length=295, Percent_Identity=30.1694915254237, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788194, Length=283, Percent_Identity=28.6219081272085, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1787690, Length=311, Percent_Identity=27.6527331189711, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI2367378, Length=323, Percent_Identity=28.7925696594427, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1789453, Length=292, Percent_Identity=27.3972602739726, Blast_Score=82, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FRZCD_MYXXA (P43500)

Other databases:

- EMBL:   J04157
- PIR:   C32185
- ProteinModelPortal:   P43500
- SMR:   P43500
- GO:   GO:0005737
- GO:   GO:0016020
- GO:   GO:0006935
- InterPro:   IPR004089
- SMART:   SM00283

Pfam domain/function: PF00015 MCPsignal

EC number: NA

Molecular weight: Translated: 43584; Mature: 43453

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLDTPNEKPAGKARARKAPASKAGATNAASTSSSTKAITDTLLTVLSGNLQARVPKELV
CCCCCCCCCCCCHHHHHCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHCCCHHHH
GESGVELAHLLNQVLDQFAASEHRKHVAAQEIDQALDALIGLVREGDLSRWNTTTEDPQL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GPLLEGFGKVIETLRTFVREINEAALRLSSSANQVLAASTQHETSSTEQAAAIHETTATM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHH
EELKHASAQIAENAGSVARVAEETLGAARAGRGAIGEFIQAMQQIRSDGVAVADSIAKLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
KRVERIGTVVEVIDEIADRSDLLALNAALEGSRAGEAGKGFSIVAAEMRRLAENVLDSTK
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
EIKNLITEIREATAAAAGAAEASKSATESGEKLGAVAAQAVEGILAGVQETSDAARVINL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATQQQRTATEQVVASMAEIEDVTRQTTQASKQATGAAAELTQLAGRLAELIKRFKAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLDTPNEKPAGKARARKAPASKAGATNAASTSSSTKAITDTLLTVLSGNLQARVPKELV
CCCCCCCCCCCHHHHHCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHCCCHHHH
GESGVELAHLLNQVLDQFAASEHRKHVAAQEIDQALDALIGLVREGDLSRWNTTTEDPQL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GPLLEGFGKVIETLRTFVREINEAALRLSSSANQVLAASTQHETSSTEQAAAIHETTATM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHH
EELKHASAQIAENAGSVARVAEETLGAARAGRGAIGEFIQAMQQIRSDGVAVADSIAKLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
KRVERIGTVVEVIDEIADRSDLLALNAALEGSRAGEAGKGFSIVAAEMRRLAENVLDSTK
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
EIKNLITEIREATAAAAGAAEASKSATESGEKLGAVAAQAVEGILAGVQETSDAARVINL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATQQQRTATEQVVASMAEIEDVTRQTTQASKQATGAAAELTQLAGRLAELIKRFKAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2492105; 1624419