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The map label for this gene is ribE [H]

Identifier: 108758043

GI number: 108758043

Start: 5964441

End: 5965103

Strand: Reverse

Name: ribE [H]

Synonym: MXAN_4763

Alternate gene names: 108758043

Gene position: 5965103-5964441 (Counterclockwise)

Preceding gene: 108757223

Following gene: 108759881

Centisome position: 65.27

GC content: 70.44

Gene sequence:

>663_bases
ATGTTTACCGGCCTCATTCAGGACCTTGGCAGGGTGGAGCGCGTCATTCCCGGCGGGATGACCGACCTGTGGATTCACAC
CTCGCTGGGCGCGGCGGCCTTCGAGCTGGGCGAGTCGATTGCCGTCAACGGCGCCTGCCTCACGGTGGTGGAGCGCACCG
GTGACAGCTTCCGCGTGCAGGCCGCGCCGGAGACGCTGCGCCGGACGACGCTGGGCTCCGTGAAGCCCGGAGACCAGGTG
AACCTGGAGCGGGCCCTGGCGCTGGGTGACCGGCTGGGCGGGCACCTGGTCTCTGGCCACGTGGACGCCGTCAGTGAGGT
GCTGGAGACGTACCCGGAGGGTGGCTCCTGGGTGATGGGGTTCCGGCTGCCGGAGGAACTGGCGCCGTACTTCATCGAGA
AGGGCTCGGTGGCCATCGACGGCATCAGCCTCACCGTCAACACCGTGGAGGCGGACCGGTTCCGGGTGCAGCTCATCCCG
GAGACGCAGGAGCGCACCACCTTGAAGGCGCGGGGCGTGGGGTCGAAGGTGAACCTGGAGGCGGACCAGATAGGGAAGTA
CGTGGCGCGGCTGTTCGCGCTCCAGCGGGGCCAGGGGGCCCCCGGGGGACGTGGCGGGCTGACGGCGGCGGCCATCGCGG
CTGCGGGGTTTGGCACGCCGTAG

Upstream 100 bases:

>100_bases
CGCCTTCGAACGCCATGGCGACGACATCCTGCTCCAGGCGCTGTTGTAGGACACGAGCGGCCGTGGGCGCAGGCGGGGCC
GGTCCGTTATAAGCGGCCCC

Downstream 100 bases:

>100_bases
CAGGCGACGCCGGGCCCCGGGGTGGTGTAGGAAGCGCGGCATGCCTCGCTACTTCGACGGTGACTTTCTACCCCCCAAGG
GCCGCTTCGCCATCTGCGTG

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MFTGLIQDLGRVERVIPGGMTDLWIHTSLGAAAFELGESIAVNGACLTVVERTGDSFRVQAAPETLRRTTLGSVKPGDQV
NLERALALGDRLGGHLVSGHVDAVSEVLETYPEGGSWVMGFRLPEELAPYFIEKGSVAIDGISLTVNTVEADRFRVQLIP
ETQERTTLKARGVGSKVNLEADQIGKYVARLFALQRGQGAPGGRGGLTAAAIAAAGFGTP

Sequences:

>Translated_220_residues
MFTGLIQDLGRVERVIPGGMTDLWIHTSLGAAAFELGESIAVNGACLTVVERTGDSFRVQAAPETLRRTTLGSVKPGDQV
NLERALALGDRLGGHLVSGHVDAVSEVLETYPEGGSWVMGFRLPEELAPYFIEKGSVAIDGISLTVNTVEADRFRVQLIP
ETQERTTLKARGVGSKVNLEADQIGKYVARLFALQRGQGAPGGRGGLTAAAIAAAGFGTP
>Mature_220_residues
MFTGLIQDLGRVERVIPGGMTDLWIHTSLGAAAFELGESIAVNGACLTVVERTGDSFRVQAAPETLRRTTLGSVKPGDQV
NLERALALGDRLGGHLVSGHVDAVSEVLETYPEGGSWVMGFRLPEELAPYFIEKGSVAIDGISLTVNTVEADRFRVQLIP
ETQERTTLKARGVGSKVNLEADQIGKYVARLFALQRGQGAPGGRGGLTAAAIAAAGFGTP

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=195, Percent_Identity=39.4871794871795, Blast_Score=131, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6319733, Length=207, Percent_Identity=38.1642512077295, Blast_Score=142, Evalue=5e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 23186; Mature: 23186

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00693 LUM_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGLIQDLGRVERVIPGGMTDLWIHTSLGAAAFELGESIAVNGACLTVVERTGDSFRVQ
CCCHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHCCCEEECCEEEEEEECCCCCEEEE
AAPETLRRTTLGSVKPGDQVNLERALALGDRLGGHLVSGHVDAVSEVLETYPEGGSWVMG
ECHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCEEECCHHHHHHHHHHHCCCCCCEEEE
FRLPEELAPYFIEKGSVAIDGISLTVNTVEADRFRVQLIPETQERTTLKARGVGSKVNLE
EECCHHHHHHHHCCCCEEEEEEEEEEEEEECCEEEEEECCCCCHHHEEHCCCCCCEEECC
ADQIGKYVARLFALQRGQGAPGGRGGLTAAAIAAAGFGTP
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MFTGLIQDLGRVERVIPGGMTDLWIHTSLGAAAFELGESIAVNGACLTVVERTGDSFRVQ
CCCHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHCCCEEECCEEEEEEECCCCCEEEE
AAPETLRRTTLGSVKPGDQVNLERALALGDRLGGHLVSGHVDAVSEVLETYPEGGSWVMG
ECHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCEEECCHHHHHHHHHHHCCCCCCEEEE
FRLPEELAPYFIEKGSVAIDGISLTVNTVEADRFRVQLIPETQERTTLKARGVGSKVNLE
EECCHHHHHHHHCCCCEEEEEEEEEEEEEECCEEEEEECCCCCHHHEEHCCCCCCEEECC
ADQIGKYVARLFALQRGQGAPGGRGGLTAAAIAAAGFGTP
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]