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The map label for this gene is ccrA [H]

Identifier: 108757789

GI number: 108757789

Start: 491641

End: 492426

Strand: Reverse

Name: ccrA [H]

Synonym: MXAN_0432

Alternate gene names: 108757789

Gene position: 492426-491641 (Counterclockwise)

Preceding gene: 108758169

Following gene: 108757002

Centisome position: 5.39

GC content: 68.83

Gene sequence:

>786_bases
ATGACGTTGTTTCCTCTTCGTTGGTTTTGTGCCGGTGCTCTTCTCATCACCCTGAGCACCGCCTGCACCCGCTCCACGCC
GGCCGCGACGGTGGAGCGGAACATCCCCGTGAAGGCGCAGTCCCAGGGTCCGGACGAATACGTGCTGGCGGATGACGTGA
GCGTGCGGAAGCTCGCGCCTGGCGTGTGGCTGCACATCACGGTGGTGACGTTGGAGCCATTCGGCCGCGTCTCCACCAAC
GGGCTCATCATCGAGGACGGTGAAACGTCCTTGCTGGTCGACACGGGCTGGGATGCACGGCAGGGCGCGCTACTGCTCGA
CTGGGCCCGGGACACGCTTCGGCGTCCGGTCCGCGCGGCGGTGGTGACGCACTTCCATGAAGATCGCCTCGGTGGTGTTC
CGGCGCTCGCCCCGCATGGCATCCCCGTCCATGGCTTGGAGGAGACGGCACGGATTGCCACGTCCCTGGGCCTGCCAGGC
CCCACGGAGACCTTCGCCAAGACGAGCACGGTGGACTCCCTGGAGCTCTTCTTCCCGGGGGCGGGCCACGCGAAGGACAA
CATCGTCGTGTGGCACCGGGACAGCGGCGTGCTGTTCGGCGGCTGCTTCGTGAAGGACGGCGCCTCGACGAACCTGGGCA
ACGTGGCGGACGCGGACGTAGCGGCCTGGCCCGCGAGCCTGTCGCGGACGCGGCAGCGGTTTCCGGAGGCGCGCGTGGTG
GTCCCGGGTCACGGACAGCCCGGTGGGCCGGAGCTGCTGGGCCACACGGAAGCGCTGCTCCGCTGA

Upstream 100 bases:

>100_bases
ACAACCGGGGCACACCGCGCCAGGCCCCAGGCCCGCCTCGGTGTGCCGCGCGAATCCCTCCACTCCGACGCGGCATCGCC
GCTGCCGAGGCCTCTTGACG

Downstream 100 bases:

>100_bases
GCGACCTCGCGGAGCAACCGGGCAGGCGCGGGCGATGTGACTGTGCCTCGCCCACACGGACAGGAGCGTTGGCCAACACA
CCGTGGTGGGTCGTCCCACG

Product: metallo-beta-lactamase family protein

Products: NA

Alternate protein names: Cephalosporinase; Imipenem-cefoxitin hydrolyzing enzyme; Penicillinase [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MTLFPLRWFCAGALLITLSTACTRSTPAATVERNIPVKAQSQGPDEYVLADDVSVRKLAPGVWLHITVVTLEPFGRVSTN
GLIIEDGETSLLVDTGWDARQGALLLDWARDTLRRPVRAAVVTHFHEDRLGGVPALAPHGIPVHGLEETARIATSLGLPG
PTETFAKTSTVDSLELFFPGAGHAKDNIVVWHRDSGVLFGGCFVKDGASTNLGNVADADVAAWPASLSRTRQRFPEARVV
VPGHGQPGGPELLGHTEALLR

Sequences:

>Translated_261_residues
MTLFPLRWFCAGALLITLSTACTRSTPAATVERNIPVKAQSQGPDEYVLADDVSVRKLAPGVWLHITVVTLEPFGRVSTN
GLIIEDGETSLLVDTGWDARQGALLLDWARDTLRRPVRAAVVTHFHEDRLGGVPALAPHGIPVHGLEETARIATSLGLPG
PTETFAKTSTVDSLELFFPGAGHAKDNIVVWHRDSGVLFGGCFVKDGASTNLGNVADADVAAWPASLSRTRQRFPEARVV
VPGHGQPGGPELLGHTEALLR
>Mature_260_residues
TLFPLRWFCAGALLITLSTACTRSTPAATVERNIPVKAQSQGPDEYVLADDVSVRKLAPGVWLHITVVTLEPFGRVSTNG
LIIEDGETSLLVDTGWDARQGALLLDWARDTLRRPVRAAVVTHFHEDRLGGVPALAPHGIPVHGLEETARIATSLGLPGP
TETFAKTSTVDSLELFFPGAGHAKDNIVVWHRDSGVLFGGCFVKDGASTNLGNVADADVAAWPASLSRTRQRFPEARVVV
PGHGQPGGPELLGHTEALLR

Specific function: Can hydrolyze carbapenem compounds [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001018
- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 27870; Mature: 27739

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLFPLRWFCAGALLITLSTACTRSTPAATVERNIPVKAQSQGPDEYVLADDVSVRKLAP
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCEEECCCCCCCEEEECCCCHHHHCC
GVWLHITVVTLEPFGRVSTNGLIIEDGETSLLVDTGWDARQGALLLDWARDTLRRPVRAA
CEEEEEEEEEECCCCCCCCCCEEEECCCEEEEEECCCCCCCCCEEEEEHHHHHHHHHHHH
VVTHFHEDRLGGVPALAPHGIPVHGLEETARIATSLGLPGPTETFAKTSTVDSLELFFPG
HHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEEECC
AGHAKDNIVVWHRDSGVLFGGCFVKDGASTNLGNVADADVAAWPASLSRTRQRFPEARVV
CCCCCCCEEEEECCCCEEEEEEEEECCCCCCCCCCCCCCHHHCCHHHHHHHHHCCCCEEE
VPGHGQPGGPELLGHTEALLR
ECCCCCCCCCHHHCCHHHHCC
>Mature Secondary Structure 
TLFPLRWFCAGALLITLSTACTRSTPAATVERNIPVKAQSQGPDEYVLADDVSVRKLAP
CCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCEEECCCCCCCEEEECCCCHHHHCC
GVWLHITVVTLEPFGRVSTNGLIIEDGETSLLVDTGWDARQGALLLDWARDTLRRPVRAA
CEEEEEEEEEECCCCCCCCCCEEEECCCEEEEEECCCCCCCCCEEEEEHHHHHHHHHHHH
VVTHFHEDRLGGVPALAPHGIPVHGLEETARIATSLGLPGPTETFAKTSTVDSLELFFPG
HHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEEECC
AGHAKDNIVVWHRDSGVLFGGCFVKDGASTNLGNVADADVAAWPASLSRTRQRFPEARVV
CCCCCCCEEEEECCCCEEEEEEEEECCCCCCCCCCCCCCHHHCCHHHHHHHHHCCCCEEE
VPGHGQPGGPELLGHTEALLR
ECCCCCCCCCHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2121094; 1956298; 2110145; 8805566; 9416622; 9578564; 10210203 [H]