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The map label for this gene is 108757730

Identifier: 108757730

GI number: 108757730

Start: 5818644

End: 5820518

Strand: Reverse

Name: 108757730

Synonym: MXAN_4639

Alternate gene names: NA

Gene position: 5820518-5818644 (Counterclockwise)

Preceding gene: 108763986

Following gene: 108761899

Centisome position: 63.68

GC content: 74.45

Gene sequence:

>1875_bases
GTGCGCCCCTCTCGCCTCCTCGTGTCCGCCCTGTTGGCCGTCCTCGTGGCGCCGGGTGTGTCCGCGGCCGCCCCGTCACG
GCGGCCGCGCGTGGACCCGGAGGCCATGCGGGAGGCCATCGACGCGGGCTCCACGGACGAAGGCCGCTACGCCTCCTCCG
CCAGCTACACGAACTATCTCCAGTCCCGGCTGAAGCACCATGCCGGGGACCACCGGGGCGCGGTGGACGCGCTGCGGCTG
GCCCTGGCCACGGATGATGGGAACCCGCTGCTGCTCACCCGGCTGGGGGAGGAGTACGCCCGTCTGGGTGATTTGACGCG
CGCGGAGCGCGAGCTGCGCCGGGCCGTGCTGCGCGCCCCCGCCTACTACCCCGCGCACGTGCTCCTGGGCCGCGTTCTCA
CGGAGTCGAAGCGGTTCGCGCGGGCCCGCCTGCACCTGCGGCGCGCGGTGACCCTCAAGCCTCGCGAGCCGGAGGCGTAT
CTCGTCCTGACCCAGCTCCACCTGGAGATGGGTGCCCCGGACGAAGCGGTGAAGGTGGTGGACGCGCTGGCGCTGGCGCT
GCCGGGGGAGGCCTCGGGGTACCAGCGCTTGGGGTTGGCGCTGGCGGAGCGGGGCGACACGGCGCGCGCCGAGCGCCTGC
TGGTAGAGGCCGCCACCCGGGCCCCGGGTGACGTGGACGTGCTGACGGCGCTGGCGCAACTGTACGAAGACACCGGCCGG
CCCGTGCAGGCGGAGGAGTCCCTGGCTCGGGCGCTGGAGCGGGACCCGGACAGCCGCGAGGTGCTGCTGGGCGCCGGACG
CGCGGCGCTGAAGGCGGGCTCCGCCGTCCGGGCGCGGGCGTACTTCGACCGGCTGTTGTCCCTCTCCTCCGAGCCGGAGA
TGCCGGTACGGGTGGCCTTCAGCTACCTCGCCGCGCGCGAGCCCAGGGCGGCCGCGGAGGTGCTGGAGGCGGCGCGCCGG
GGGGACCATGCGGACCCTCGGCTGGCCTACTACGCGGGGCTCGTCCATGAGCGGATGCGCCGCTTCGCCGACGCGGCGGA
GGCCTTCGCTGGTGTGCCCGCTGAGGCGGATGTCTACGCCGACGCGCGCCTGCGCCGAGCCCGCAGCCTGTCGCTCCTGG
GCGAGCACTCCCGGGCCCTCACGCTCTTCCGGGCCGCGATGCAGGAGTCGCCAGCGGACGTGGAAGTCCGGATGCAGTTC
GCCCGGGCCCTGGAGCGCGGCGGCACGCCGAACCGCGCGGAGCTGCTCCTTCGCGAGGGCCTGTCCGCCGGTCCCTCCGC
GGCGTTGTATGACGCCCTGGCCGCCACGCTCCACCGACAGGGCCGGGGTCGCGAAGCACTGACACTGCTTCGCGGGGCGG
TGGCCCGCTTTCCCCGGGACGAAGACCTGCTGTACGTGCTGGGCGCGGCCCATGAGCGACAGGGCGACGTGACGGGCGCG
CTGGCCCGCATGCGGGCGGTGCTGGCTGTGTCACCGGACCACGCCGCCGCGCTGAACTTCCTGGGCTACCTGCTGGCGCA
GGCGGGGCAGAACCTGGACGAGGCCGAGCGGCGCGTGCGGCGGGCACTGGAGCTGCGGCCGGACACCGGGGCCTACCTGG
ACTCACTGGGCTGGGTGTACTTCCGGCGAGGGGACTACGCCCGGGCCGTGGACGCGCTGGAGCGAGCCTCCACGCTGGCT
CCGGATGAGCCCGTCATCCTCGAACACCTGGGAGACGCCTATCAGCGGGTGGCGAGGACGGACGACGCCGCGGCGGTCTG
GCGGCGCGCCCTGGAAGTGCTGACGCTGGATCCTGAGTCCGCCGAGCCACCCGGCCAGCGCGCCGCGTTGGAGCGCAAGC
TCAATGCGCTACCCACGCGTGCGCCAGACCGCTAA

Upstream 100 bases:

>100_bases
GACTCGGTCGAGAAGCTGCTGGAGAAGCTGGGCGCGCCGGCCCCCGAAGAGACCTGAGGTGACTGCGCGCGGGACGGGCT
CACGCTAGACTCATGCTCGC

Downstream 100 bases:

>100_bases
GTTGGTGGGCCTATGGCGCGTAGCGACGAGGGCTTCTTTCCCGGCAGGGACGGGACACGACTGTACTGGAAGTCCATCCT
TCCAGACGCCGAGCCTCGCG

Product: TPR domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 624; Mature: 624

Protein sequence:

>624_residues
MRPSRLLVSALLAVLVAPGVSAAAPSRRPRVDPEAMREAIDAGSTDEGRYASSASYTNYLQSRLKHHAGDHRGAVDALRL
ALATDDGNPLLLTRLGEEYARLGDLTRAERELRRAVLRAPAYYPAHVLLGRVLTESKRFARARLHLRRAVTLKPREPEAY
LVLTQLHLEMGAPDEAVKVVDALALALPGEASGYQRLGLALAERGDTARAERLLVEAATRAPGDVDVLTALAQLYEDTGR
PVQAEESLARALERDPDSREVLLGAGRAALKAGSAVRARAYFDRLLSLSSEPEMPVRVAFSYLAAREPRAAAEVLEAARR
GDHADPRLAYYAGLVHERMRRFADAAEAFAGVPAEADVYADARLRRARSLSLLGEHSRALTLFRAAMQESPADVEVRMQF
ARALERGGTPNRAELLLREGLSAGPSAALYDALAATLHRQGRGREALTLLRGAVARFPRDEDLLYVLGAAHERQGDVTGA
LARMRAVLAVSPDHAAALNFLGYLLAQAGQNLDEAERRVRRALELRPDTGAYLDSLGWVYFRRGDYARAVDALERASTLA
PDEPVILEHLGDAYQRVARTDDAAAVWRRALEVLTLDPESAEPPGQRAALERKLNALPTRAPDR

Sequences:

>Translated_624_residues
MRPSRLLVSALLAVLVAPGVSAAAPSRRPRVDPEAMREAIDAGSTDEGRYASSASYTNYLQSRLKHHAGDHRGAVDALRL
ALATDDGNPLLLTRLGEEYARLGDLTRAERELRRAVLRAPAYYPAHVLLGRVLTESKRFARARLHLRRAVTLKPREPEAY
LVLTQLHLEMGAPDEAVKVVDALALALPGEASGYQRLGLALAERGDTARAERLLVEAATRAPGDVDVLTALAQLYEDTGR
PVQAEESLARALERDPDSREVLLGAGRAALKAGSAVRARAYFDRLLSLSSEPEMPVRVAFSYLAAREPRAAAEVLEAARR
GDHADPRLAYYAGLVHERMRRFADAAEAFAGVPAEADVYADARLRRARSLSLLGEHSRALTLFRAAMQESPADVEVRMQF
ARALERGGTPNRAELLLREGLSAGPSAALYDALAATLHRQGRGREALTLLRGAVARFPRDEDLLYVLGAAHERQGDVTGA
LARMRAVLAVSPDHAAALNFLGYLLAQAGQNLDEAERRVRRALELRPDTGAYLDSLGWVYFRRGDYARAVDALERASTLA
PDEPVILEHLGDAYQRVARTDDAAAVWRRALEVLTLDPESAEPPGQRAALERKLNALPTRAPDR
>Mature_624_residues
MRPSRLLVSALLAVLVAPGVSAAAPSRRPRVDPEAMREAIDAGSTDEGRYASSASYTNYLQSRLKHHAGDHRGAVDALRL
ALATDDGNPLLLTRLGEEYARLGDLTRAERELRRAVLRAPAYYPAHVLLGRVLTESKRFARARLHLRRAVTLKPREPEAY
LVLTQLHLEMGAPDEAVKVVDALALALPGEASGYQRLGLALAERGDTARAERLLVEAATRAPGDVDVLTALAQLYEDTGR
PVQAEESLARALERDPDSREVLLGAGRAALKAGSAVRARAYFDRLLSLSSEPEMPVRVAFSYLAAREPRAAAEVLEAARR
GDHADPRLAYYAGLVHERMRRFADAAEAFAGVPAEADVYADARLRRARSLSLLGEHSRALTLFRAAMQESPADVEVRMQF
ARALERGGTPNRAELLLREGLSAGPSAALYDALAATLHRQGRGREALTLLRGAVARFPRDEDLLYVLGAAHERQGDVTGA
LARMRAVLAVSPDHAAALNFLGYLLAQAGQNLDEAERRVRRALELRPDTGAYLDSLGWVYFRRGDYARAVDALERASTLA
PDEPVILEHLGDAYQRVARTDDAAAVWRRALEVLTLDPESAEPPGQRAALERKLNALPTRAPDR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 5 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307150, Length=438, Percent_Identity=25.7990867579909, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI32307148, Length=438, Percent_Identity=25.7990867579909, Blast_Score=74, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011717
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR013105
- InterPro:   IPR019734 [H]

Pfam domain/function: PF07719 TPR_2; PF07721 TPR_4 [H]

EC number: NA

Molecular weight: Translated: 68030; Mature: 68030

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPSRLLVSALLAVLVAPGVSAAAPSRRPRVDPEAMREAIDAGSTDEGRYASSASYTNYL
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHH
QSRLKHHAGDHRGAVDALRLALATDDGNPLLLTRLGEEYARLGDLTRAERELRRAVLRAP
HHHHHHCCCCCCHHHHHHHHHHEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AYYPAHVLLGRVLTESKRFARARLHLRRAVTLKPREPEAYLVLTQLHLEMGAPDEAVKVV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHCCCCHHHHHHH
DALALALPGEASGYQRLGLALAERGDTARAERLLVEAATRAPGDVDVLTALAQLYEDTGR
HHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
PVQAEESLARALERDPDSREVLLGAGRAALKAGSAVRARAYFDRLLSLSSEPEMPVRVAF
CCCHHHHHHHHHHCCCCCCCEEEECCHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHH
SYLAAREPRAAAEVLEAARRGDHADPRLAYYAGLVHERMRRFADAAEAFAGVPAEADVYA
HHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
DARLRRARSLSLLGEHSRALTLFRAAMQESPADVEVRMQFARALERGGTPNRAELLLREG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHC
LSAGPSAALYDALAATLHRQGRGREALTLLRGAVARFPRDEDLLYVLGAAHERQGDVTGA
CCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHH
LARMRAVLAVSPDHAAALNFLGYLLAQAGQNLDEAERRVRRALELRPDTGAYLDSLGWVY
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCE
FRRGDYARAVDALERASTLAPDEPVILEHLGDAYQRVARTDDAAAVWRRALEVLTLDPES
EECCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEECCCC
AEPPGQRAALERKLNALPTRAPDR
CCCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRPSRLLVSALLAVLVAPGVSAAAPSRRPRVDPEAMREAIDAGSTDEGRYASSASYTNYL
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHH
QSRLKHHAGDHRGAVDALRLALATDDGNPLLLTRLGEEYARLGDLTRAERELRRAVLRAP
HHHHHHCCCCCCHHHHHHHHHHEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AYYPAHVLLGRVLTESKRFARARLHLRRAVTLKPREPEAYLVLTQLHLEMGAPDEAVKVV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHCCCCHHHHHHH
DALALALPGEASGYQRLGLALAERGDTARAERLLVEAATRAPGDVDVLTALAQLYEDTGR
HHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
PVQAEESLARALERDPDSREVLLGAGRAALKAGSAVRARAYFDRLLSLSSEPEMPVRVAF
CCCHHHHHHHHHHCCCCCCCEEEECCHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHH
SYLAAREPRAAAEVLEAARRGDHADPRLAYYAGLVHERMRRFADAAEAFAGVPAEADVYA
HHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
DARLRRARSLSLLGEHSRALTLFRAAMQESPADVEVRMQFARALERGGTPNRAELLLREG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHC
LSAGPSAALYDALAATLHRQGRGREALTLLRGAVARFPRDEDLLYVLGAAHERQGDVTGA
CCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHH
LARMRAVLAVSPDHAAALNFLGYLLAQAGQNLDEAERRVRRALELRPDTGAYLDSLGWVY
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCE
FRRGDYARAVDALERASTLAPDEPVILEHLGDAYQRVARTDDAAAVWRRALEVLTLDPES
EECCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEECCCC
AEPPGQRAALERKLNALPTRAPDR
CCCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7883699; 10984043 [H]