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The map label for this gene is pkn2 [H]

Identifier: 108757627

GI number: 108757627

Start: 5142777

End: 5144147

Strand: Reverse

Name: pkn2 [H]

Synonym: MXAN_4188

Alternate gene names: 108757627

Gene position: 5144147-5142777 (Counterclockwise)

Preceding gene: 108763791

Following gene: 108758364

Centisome position: 56.28

GC content: 69.73

Gene sequence:

>1371_bases
TTGGTACGCAGTTGCGATTGCACCATCGACGGTGGCGCATACACTGCGCGGGCTTTGAAGACCGCCAACCTCGCCATCGT
CTTCACCGACATCAAGGGCTTCACCGAGCGGACCAGCCGGCAGACGCTGGAGGAGAACCAGCGCCTGCTCCAGGTCCACG
AGGCCCTGCTGGCGCCGCTGTTCAAGGCGTTTGGCGGGCGCATCGTCAAGTCCATCGGTGACGCGTACCTCGTCACCTTC
GAATCGCCCACCCAGGCGGTGCTCAGCGGCATCGCCATCCAGGATCGGCTGTGGCACCACAACCGGACGGTGGAGGTGTC
GGAGCAGATTCACGTCCGCGTGGCCATCAACGTAGGCGAGGTGCGGCTGGACGGGAACGACATCTTCGGCGAGCCCGTCA
ACATCGCCGCCCGGGTGGAGGGCATCGCCGAGGCGGGCGAGGTGTACTTCACCGAGGCCGTCTACCTGGCGATGAACAAG
GCCGAGGTGCCTTCCAAGGAAGTGGGCGCCTACGAGCTGAAGGGCATCCCGGGGAAGATTCGCGTCTTCCACGTGCCCCG
GGCGCCGTACCGCGTGGAGGCTCCCGCGCCCAGCGCCATCGCCGAGACGCCGGGCTCCGAATCGATGCCGCCCTTCGGGA
ACCTGGCCCTGTCCCGCGTGTCGGAGGCTTCGTCACCGGGGGCGCAGGTGGACCTGTCCGTGCTGGGGCAGCGGGCCGCT
GCGGGCGCCGCGGTCATCAGCCAACGCGCGGCCGCGGGTGCCACGGTGCTGGGCCAGCAGGCCGCGGAGCTCGGGCGGCA
GGCGCGCACGGTGGGCGGTTCGCTCTTTTCGCGCGGCATGGCGACGCTTCCGCCGCAGGTCCAGAAGCACCGCGCGCTGG
TGGGCGTGGGCGCGGCCGTCGTGCTCGCGGGCGTCGCGATGCTGGCGTTCAGTGGCGACGAGACGGTGCGCGCCATCAAG
GCGGTGGAGCGGGCGCCGGAGGAGGAGCGGACCGCGCTGGCCAAGGACGTCCGGACCCTCATCATGAAGGAGGAGGACTC
CGGGCGGCGCAACTTCCTGCTGGGCCGTCTGACGGAAGCGACGGGCAAGCCCGATGACGCGCTGAAGGTCTACGCCACGG
CCGTGAAGGCCGGCAGCCGCGCCGCGGAGGACCGCCTCATCGAGATGCTGTCGCATGCGCGATGCGACGTGCGCTCGGAT
GCCGCGTCCACGGTAGGCCGGCTCCAGTTGAAGCGGGCGGTGAGCGCCCTGGAGGACCTGAAGTCCGACGGTGGGCCCGA
TGACGGGGTGCGGACGGGCCTGTTCGGCATTTCCAAGTGCGACTCGAAGGTGGCCGCGGAAAGCGCGCTCAAGGGCTTCA
AGGAGCGTTGA

Upstream 100 bases:

>100_bases
GGCCCCAGCTCGCGGAGCGGGTCCGCGCGGCGCTGGAAGCCCCTCCGAAGCGGCGAATGCGTGACCTCAAACCATCACGT
CGCTGACAGCGAGCGGTCAT

Downstream 100 bases:

>100_bases
TGTGCCGGCCCTCGAGGCTGGCTGAGGAAGGGAACGCCGTGACGAAGGTGAAGACGGGACTGGACGTGTGGGTGGAGCAG
GGCTTCTCCGCGTTGAAGGG

Product: adenylate/guanylate cyclase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MVRSCDCTIDGGAYTARALKTANLAIVFTDIKGFTERTSRQTLEENQRLLQVHEALLAPLFKAFGGRIVKSIGDAYLVTF
ESPTQAVLSGIAIQDRLWHHNRTVEVSEQIHVRVAINVGEVRLDGNDIFGEPVNIAARVEGIAEAGEVYFTEAVYLAMNK
AEVPSKEVGAYELKGIPGKIRVFHVPRAPYRVEAPAPSAIAETPGSESMPPFGNLALSRVSEASSPGAQVDLSVLGQRAA
AGAAVISQRAAAGATVLGQQAAELGRQARTVGGSLFSRGMATLPPQVQKHRALVGVGAAVVLAGVAMLAFSGDETVRAIK
AVERAPEEERTALAKDVRTLIMKEEDSGRRNFLLGRLTEATGKPDDALKVYATAVKAGSRAAEDRLIEMLSHARCDVRSD
AASTVGRLQLKRAVSALEDLKSDGGPDDGVRTGLFGISKCDSKVAAESALKGFKER

Sequences:

>Translated_456_residues
MVRSCDCTIDGGAYTARALKTANLAIVFTDIKGFTERTSRQTLEENQRLLQVHEALLAPLFKAFGGRIVKSIGDAYLVTF
ESPTQAVLSGIAIQDRLWHHNRTVEVSEQIHVRVAINVGEVRLDGNDIFGEPVNIAARVEGIAEAGEVYFTEAVYLAMNK
AEVPSKEVGAYELKGIPGKIRVFHVPRAPYRVEAPAPSAIAETPGSESMPPFGNLALSRVSEASSPGAQVDLSVLGQRAA
AGAAVISQRAAAGATVLGQQAAELGRQARTVGGSLFSRGMATLPPQVQKHRALVGVGAAVVLAGVAMLAFSGDETVRAIK
AVERAPEEERTALAKDVRTLIMKEEDSGRRNFLLGRLTEATGKPDDALKVYATAVKAGSRAAEDRLIEMLSHARCDVRSD
AASTVGRLQLKRAVSALEDLKSDGGPDDGVRTGLFGISKCDSKVAAESALKGFKER
>Mature_456_residues
MVRSCDCTIDGGAYTARALKTANLAIVFTDIKGFTERTSRQTLEENQRLLQVHEALLAPLFKAFGGRIVKSIGDAYLVTF
ESPTQAVLSGIAIQDRLWHHNRTVEVSEQIHVRVAINVGEVRLDGNDIFGEPVNIAARVEGIAEAGEVYFTEAVYLAMNK
AEVPSKEVGAYELKGIPGKIRVFHVPRAPYRVEAPAPSAIAETPGSESMPPFGNLALSRVSEASSPGAQVDLSVLGQRAA
AGAAVISQRAAAGATVLGQQAAELGRQARTVGGSLFSRGMATLPPQVQKHRALVGVGAAVVLAGVAMLAFSGDETVRAIK
AVERAPEEERTALAKDVRTLIMKEEDSGRRNFLLGRLTEATGKPDDALKVYATAVKAGSRAAEDRLIEMLSHARCDVRSD
AASTVGRLQLKRAVSALEDLKSDGGPDDGVRTGLFGISKCDSKVAAESALKGFKER

Specific function: Regulates the activity of endogenous beta-lactamase or related enzymes, by blocking their secretion by phosphorylation, in response to an external signal yet to be identified [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017441
- InterPro:   IPR017442
- InterPro:   IPR008271
- InterPro:   IPR002290 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 48408; Mature: 48408

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRSCDCTIDGGAYTARALKTANLAIVFTDIKGFTERTSRQTLEENQRLLQVHEALLAPL
CCCCCCEEECCCCHHHHHHEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FKAFGGRIVKSIGDAYLVTFESPTQAVLSGIAIQDRLWHHNRTVEVSEQIHVRVAINVGE
HHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCEEECCEEEEEEEEEEEE
VRLDGNDIFGEPVNIAARVEGIAEAGEVYFTEAVYLAMNKAEVPSKEVGAYELKGIPGKI
EEECCCCCCCCCCCHHHHHHHHHHCCCEEEEEHEEEEECCCCCCCHHCCCEEECCCCCEE
RVFHVPRAPYRVEAPAPSAIAETPGSESMPPFGNLALSRVSEASSPGAQVDLSVLGQRAA
EEEECCCCCEEECCCCCCHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEHHHHHHHHH
AGAAVISQRAAAGATVLGQQAAELGRQARTVGGSLFSRGMATLPPQVQKHRALVGVGAAV
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
VLAGVAMLAFSGDETVRAIKAVERAPEEERTALAKDVRTLIMKEEDSGRRNFLLGRLTEA
HHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHC
TGKPDDALKVYATAVKAGSRAAEDRLIEMLSHARCDVRSDAASTVGRLQLKRAVSALEDL
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KSDGGPDDGVRTGLFGISKCDSKVAAESALKGFKER
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVRSCDCTIDGGAYTARALKTANLAIVFTDIKGFTERTSRQTLEENQRLLQVHEALLAPL
CCCCCCEEECCCCHHHHHHEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FKAFGGRIVKSIGDAYLVTFESPTQAVLSGIAIQDRLWHHNRTVEVSEQIHVRVAINVGE
HHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCEEECCEEEEEEEEEEEE
VRLDGNDIFGEPVNIAARVEGIAEAGEVYFTEAVYLAMNKAEVPSKEVGAYELKGIPGKI
EEECCCCCCCCCCCHHHHHHHHHHCCCEEEEEHEEEEECCCCCCCHHCCCEEECCCCCEE
RVFHVPRAPYRVEAPAPSAIAETPGSESMPPFGNLALSRVSEASSPGAQVDLSVLGQRAA
EEEECCCCCEEECCCCCCHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEHHHHHHHHH
AGAAVISQRAAAGATVLGQQAAELGRQARTVGGSLFSRGMATLPPQVQKHRALVGVGAAV
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
VLAGVAMLAFSGDETVRAIKAVERAPEEERTALAKDVRTLIMKEEDSGRRNFLLGRLTEA
HHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHC
TGKPDDALKVYATAVKAGSRAAEDRLIEMLSHARCDVRSDAASTVGRLQLKRAVSALEDL
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KSDGGPDDGVRTGLFGISKCDSKVAAESALKGFKER
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7774814 [H]