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The map label for this gene is 108757590

Identifier: 108757590

GI number: 108757590

Start: 3836877

End: 3838670

Strand: Direct

Name: 108757590

Synonym: MXAN_3285

Alternate gene names: NA

Gene position: 3836877-3838670 (Clockwise)

Preceding gene: 108758039

Following gene: 108757770

Centisome position: 41.98

GC content: 71.13

Gene sequence:

>1794_bases
ATGCGGAAGGTGCGATGGACCCTGGGGGGCGCGGCGCTGGCCCTGACGCTGTCGGCCGCCTGTGCGTCCGCTTCTCGTGA
GCAGGACACGCCTCCCCCTGCGAATCTGCGGGCGCTCGATGCGCGGGACGTGGTGGCGGGCGCCATCGTCGTGGACTTCA
AGGACGGCACGACGAAGGCGGAGTTCGACGCCTGGGAGGCCGACTGGGGCGTCGACCTGGAACTCAACTCCGTGGAGAGC
GCCGACGAGGCCCTCACGGTGGCGGTGGGCGTGGACGACGTGGACGGGGTGCTCGAGCGCATCCGCCAGCACCCCGCCGT
GGAAGCCGCCGAGCCGTTGATGGAGGTCCGCGCCAGTTTCACGCCGAACGACCCGCATTTCGCGCAGCAGTGGAACCTGC
GGATGATCGACATGCCCAAGGCCTGGGAGCGCAACCGGGGCAAGGGCGTGGTGGTGGCGGTGCTGGACACTGGCATCGCG
TACGAGGACCACGGCGACTTCAAGCAGGCGCCGGACCTCAAGGGCGTGAAGTTCGTGAAGGGCTTCGACTTCGTCAACGA
CGACGAGCACGCCAACGACGACCACGGGCACGGCACGCACGTGGCGGGCACCATCGCCCAGGCCACCAACAATGGCGAAG
GCGTGGCGGGAGTGGCCTTCGAGGCGACGCTGATGCCCGTCAAGGTGCTCAACCACTTCGGTGGCGGGAACACGGCGGAC
ATCGCGGACGCCATCCGCTTCGCGGCGGACAAGGGTGCGAACGTCATCAACCTGTCCCTGGGCGGCGGGGCGTACTCGCA
GGTGATGGCCAGCGCGGTCGAGTACGCGCGCAAGAAGGGCGTCACCGTGGTGGCCGCGGCCGGCAACGGCGGGCGGGCGA
CGGTGGAATTCCCCGCGGCCTACCCGGGCGCGGTGGCGGTGTCGGCCGTGGGGCCGGACGGTGTGCTGGCGCCCTATTCC
TCCTACGGCAAGGAGTTGGACATCGCCGCGCCGGGTGGTGACAAGCGCCGGGGCGACCAGGGGGGCATCCTCCAGAACAC
CCTCGACCCGCGGGACGTCTCGCGCTTCGTCTACGCGTCCTACCAGGGCACCAGCATGGCCACGCCGCACGTCGCGGCGG
TGGCGGCGATGCTCTACGCGGCCGGCGCCAAGGGACCGGACGAGGTGGAGCAGGCCCTCTACGCGGGCGCGAAGAAGTCC
GCGGACCAGGCGTGGAGCGAGCAGTACGGCCACGGCCTGCTCAACGCCGAGGCGTCGCTCGCGTCGCTGCGCGGCGGCGG
CTTGGCACAGTGGCCGCCGCTGTACTGGGCGCTGGCGCTGCTGGCGTTCGTGCTGCTGACGCTGCGAGGCCGTGCGCGGC
CGGGCTACCTCAACGTGCTGGTGCGGCCCGCCTTCCTCATCCCGCTGCTGCTCTCGACGGTGGGGGCCTTCTTCCTGCGC
GGCTGGTTCGGGGGCGCTGAGGGGGCCGCAGGAGACGTGGTGCAGGTGGCGTCGCTGCCCCTGCCGGATTGGGAGCGCAT
CATCTTCGGCCGGGGCCGGACGGTGAACCCGCTGTTCTACAGCGCGCTCATCCCGCTGCTCCTGTCGCTGCCGGCCATCA
AGTGGCGGGGGCTGCGGTCGGCCATGGGGGGCCTGGCGCTCGGCTTCGCGGGCTTCCTGGCCTACACGGCCTGGGCCGGA
GCGCCGGCGCTGGCGTGGCTGCCCTTCGCGTTCCTTGCCAAGCCCTGGCTGGGCTTCAACACCGTCATCTGCCTCGTCAT
CGCCCGCGCGATGCTCCAGAAGGAGGACGCATGA

Upstream 100 bases:

>100_bases
GGAGAGGGGACATCCAGACTGTCGGTGCAGACCCAATCGTTGTGACGTTCGTTCGTAGGGGTCTTCCAGACGCGTGTTTC
GTTTCTCAAGGAGTGGCCTG

Downstream 100 bases:

>100_bases
AGCTCACTGGCCGCGTCGTGTTCCGTGACATCGAAACGGGGGTCTGGGTGCTGGAGGGAGACGACGGCACCACGTACCAG
CTCGCTGGCGGGGACCGGAA

Product: S8A family peptidase

Products: NA

Alternate protein names: Ak.1 protease [H]

Number of amino acids: Translated: 597; Mature: 597

Protein sequence:

>597_residues
MRKVRWTLGGAALALTLSAACASASREQDTPPPANLRALDARDVVAGAIVVDFKDGTTKAEFDAWEADWGVDLELNSVES
ADEALTVAVGVDDVDGVLERIRQHPAVEAAEPLMEVRASFTPNDPHFAQQWNLRMIDMPKAWERNRGKGVVVAVLDTGIA
YEDHGDFKQAPDLKGVKFVKGFDFVNDDEHANDDHGHGTHVAGTIAQATNNGEGVAGVAFEATLMPVKVLNHFGGGNTAD
IADAIRFAADKGANVINLSLGGGAYSQVMASAVEYARKKGVTVVAAAGNGGRATVEFPAAYPGAVAVSAVGPDGVLAPYS
SYGKELDIAAPGGDKRRGDQGGILQNTLDPRDVSRFVYASYQGTSMATPHVAAVAAMLYAAGAKGPDEVEQALYAGAKKS
ADQAWSEQYGHGLLNAEASLASLRGGGLAQWPPLYWALALLAFVLLTLRGRARPGYLNVLVRPAFLIPLLLSTVGAFFLR
GWFGGAEGAAGDVVQVASLPLPDWERIIFGRGRTVNPLFYSALIPLLLSLPAIKWRGLRSAMGGLALGFAGFLAYTAWAG
APALAWLPFAFLAKPWLGFNTVICLVIARAMLQKEDA

Sequences:

>Translated_597_residues
MRKVRWTLGGAALALTLSAACASASREQDTPPPANLRALDARDVVAGAIVVDFKDGTTKAEFDAWEADWGVDLELNSVES
ADEALTVAVGVDDVDGVLERIRQHPAVEAAEPLMEVRASFTPNDPHFAQQWNLRMIDMPKAWERNRGKGVVVAVLDTGIA
YEDHGDFKQAPDLKGVKFVKGFDFVNDDEHANDDHGHGTHVAGTIAQATNNGEGVAGVAFEATLMPVKVLNHFGGGNTAD
IADAIRFAADKGANVINLSLGGGAYSQVMASAVEYARKKGVTVVAAAGNGGRATVEFPAAYPGAVAVSAVGPDGVLAPYS
SYGKELDIAAPGGDKRRGDQGGILQNTLDPRDVSRFVYASYQGTSMATPHVAAVAAMLYAAGAKGPDEVEQALYAGAKKS
ADQAWSEQYGHGLLNAEASLASLRGGGLAQWPPLYWALALLAFVLLTLRGRARPGYLNVLVRPAFLIPLLLSTVGAFFLR
GWFGGAEGAAGDVVQVASLPLPDWERIIFGRGRTVNPLFYSALIPLLLSLPAIKWRGLRSAMGGLALGFAGFLAYTAWAG
APALAWLPFAFLAKPWLGFNTVICLVIARAMLQKEDA
>Mature_597_residues
MRKVRWTLGGAALALTLSAACASASREQDTPPPANLRALDARDVVAGAIVVDFKDGTTKAEFDAWEADWGVDLELNSVES
ADEALTVAVGVDDVDGVLERIRQHPAVEAAEPLMEVRASFTPNDPHFAQQWNLRMIDMPKAWERNRGKGVVVAVLDTGIA
YEDHGDFKQAPDLKGVKFVKGFDFVNDDEHANDDHGHGTHVAGTIAQATNNGEGVAGVAFEATLMPVKVLNHFGGGNTAD
IADAIRFAADKGANVINLSLGGGAYSQVMASAVEYARKKGVTVVAAAGNGGRATVEFPAAYPGAVAVSAVGPDGVLAPYS
SYGKELDIAAPGGDKRRGDQGGILQNTLDPRDVSRFVYASYQGTSMATPHVAAVAAMLYAAGAKGPDEVEQALYAGAKKS
ADQAWSEQYGHGLLNAEASLASLRGGGLAQWPPLYWALALLAFVLLTLRGRARPGYLNVLVRPAFLIPLLLSTVGAFFLR
GWFGGAEGAAGDVVQVASLPLPDWERIIFGRGRTVNPLFYSALIPLLLSLPAIKWRGLRSAMGGLALGFAGFLAYTAWAG
APALAWLPFAFLAKPWLGFNTVICLVIARAMLQKEDA

Specific function: Unknown

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320775, Length=301, Percent_Identity=31.2292358803987, Blast_Score=84, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6324576, Length=313, Percent_Identity=29.3929712460064, Blast_Score=81, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6319893, Length=262, Percent_Identity=29.7709923664122, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI45550681, Length=362, Percent_Identity=27.6243093922652, Blast_Score=82, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR009020 [H]

Pfam domain/function: PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 62947; Mature: 62947

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00136 SUBTILASE_ASP ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKVRWTLGGAALALTLSAACASASREQDTPPPANLRALDARDVVAGAIVVDFKDGTTKA
CCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEECHHHHEEEEEEEEECCCCCCC
EFDAWEADWGVDLELNSVESADEALTVAVGVDDVDGVLERIRQHPAVEAAEPLMEVRASF
CCCCCCCCCCCEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHCC
TPNDPHFAQQWNLRMIDMPKAWERNRGKGVVVAVLDTGIAYEDHGDFKQAPDLKGVKFVK
CCCCCCHHHCCCEEEEECCCHHHCCCCCEEEEEEEECCCEECCCCCCCCCCCCCCEEEEE
GFDFVNDDEHANDDHGHGTHVAGTIAQATNNGEGVAGVAFEATLMPVKVLNHFGGGNTAD
CCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHCCCCCHHH
IADAIRFAADKGANVINLSLGGGAYSQVMASAVEYARKKGVTVVAAAGNGGRATVEFPAA
HHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEECCCC
YPGAVAVSAVGPDGVLAPYSSYGKELDIAAPGGDKRRGDQGGILQNTLDPRDVSRFVYAS
CCCCEEEEECCCCCCCCCHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHEEE
YQGTSMATPHVAAVAAMLYAAGAKGPDEVEQALYAGAKKSADQAWSEQYGHGLLNAEASL
CCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHH
ASLRGGGLAQWPPLYWALALLAFVLLTLRGRARPGYLNVLVRPAFLIPLLLSTVGAFFLR
HHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GWFGGAEGAAGDVVQVASLPLPDWERIIFGRGRTVNPLFYSALIPLLLSLPAIKWRGLRS
HHCCCCCCCCCCEEEECCCCCCCHHHHEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
AMGGLALGFAGFLAYTAWAGAPALAWLPFAFLAKPWLGFNTVICLVIARAMLQKEDA
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRKVRWTLGGAALALTLSAACASASREQDTPPPANLRALDARDVVAGAIVVDFKDGTTKA
CCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEECHHHHEEEEEEEEECCCCCCC
EFDAWEADWGVDLELNSVESADEALTVAVGVDDVDGVLERIRQHPAVEAAEPLMEVRASF
CCCCCCCCCCCEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHCC
TPNDPHFAQQWNLRMIDMPKAWERNRGKGVVVAVLDTGIAYEDHGDFKQAPDLKGVKFVK
CCCCCCHHHCCCEEEEECCCHHHCCCCCEEEEEEEECCCEECCCCCCCCCCCCCCEEEEE
GFDFVNDDEHANDDHGHGTHVAGTIAQATNNGEGVAGVAFEATLMPVKVLNHFGGGNTAD
CCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHCCCCCHHH
IADAIRFAADKGANVINLSLGGGAYSQVMASAVEYARKKGVTVVAAAGNGGRATVEFPAA
HHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEECCCC
YPGAVAVSAVGPDGVLAPYSSYGKELDIAAPGGDKRRGDQGGILQNTLDPRDVSRFVYAS
CCCCEEEEECCCCCCCCCHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHEEE
YQGTSMATPHVAAVAAMLYAAGAKGPDEVEQALYAGAKKSADQAWSEQYGHGLLNAEASL
CCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHH
ASLRGGGLAQWPPLYWALALLAFVLLTLRGRARPGYLNVLVRPAFLIPLLLSTVGAFFLR
HHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GWFGGAEGAAGDVVQVASLPLPDWERIIFGRGRTVNPLFYSALIPLLLSLPAIKWRGLRS
HHCCCCCCCCCCEEEECCCCCCCHHHHEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
AMGGLALGFAGFLAYTAWAGAPALAWLPFAFLAKPWLGFNTVICLVIARAMLQKEDA
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7993087; 10588904 [H]