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The map label for this gene is kdsC [H]

Identifier: 108757519

GI number: 108757519

Start: 1273844

End: 1274449

Strand: Reverse

Name: kdsC [H]

Synonym: MXAN_1094

Alternate gene names: 108757519

Gene position: 1274449-1273844 (Counterclockwise)

Preceding gene: 108758560

Following gene: 108763279

Centisome position: 13.94

GC content: 66.17

Gene sequence:

>606_bases
GTGTCGGCAAACAAGGGAGTCGAGCAAGCCATGGTGACGGACGCCCCTTCCAGACTGGCAACGGAAGAGCTGATGTCCCG
TGCTGCGCGCGTGCGGCTGCTCGTCTTCGACGTGGACGGGGTTCTCACCGACGGCGGCCTCTACTACGGCCAGGACGGCG
AGCTGATGAAGCGCTTCGACGTCAAGGACGGCCATGCGCTCGTCATGGCCCGGCTGTCCGGGTTGCCCGCCGCCATCCTC
ACCGCCCGCACCTCCGGCATCGTGGAGAAGCGCGGGCGGGAGCTGGGCCTCGCGGCCGTGTTCCAAGGCCGCCGTGACAA
GTCGGCCGCTCTCAAAGAGTTGGTCACCCAGTTGGACGTGCCCTTGGACGCCTGCGCGTACATGGGTGACGACCACAACG
ACCTGGGTCCACTTTCAATGGTGGCTCTTTCCGCTTGTCCTGCGGATGCGGTCCCCGAAGTGCGCCGCGAGGCACACTTC
GTTACCCAGAGTCCTGGCGGCCGAGGGGCCGCTCGCGAACTCGTGGAGCTGTGTCTCAAGGCCAGTGGCCGCTGGGACGA
CGCAGTGGGTCTGATGAGAGGGACTGATAGGCGCGGTACTCAGTGA

Upstream 100 bases:

>100_bases
CTGTGTGACGGTCCCTGTTCGCTGAATCCACAGATGTTTGAAGACGTGGTACGAAACGTGCTGAGCATCCGCCGGGTGTT
GGGCCACGAGCCGGGTTGAT

Downstream 100 bases:

>100_bases
GGTTGAAGAAAACCCGTGTTCAAGGTAGGTGAATAGTTCCATGGGCAGCGGAATCATGCAGCAAGAGGGGAGTACGGCCA
TGACGGACCAGCTCTACACG

Product: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MSANKGVEQAMVTDAPSRLATEELMSRAARVRLLVFDVDGVLTDGGLYYGQDGELMKRFDVKDGHALVMARLSGLPAAIL
TARTSGIVEKRGRELGLAAVFQGRRDKSAALKELVTQLDVPLDACAYMGDDHNDLGPLSMVALSACPADAVPEVRREAHF
VTQSPGGRGAARELVELCLKASGRWDDAVGLMRGTDRRGTQ

Sequences:

>Translated_201_residues
MSANKGVEQAMVTDAPSRLATEELMSRAARVRLLVFDVDGVLTDGGLYYGQDGELMKRFDVKDGHALVMARLSGLPAAIL
TARTSGIVEKRGRELGLAAVFQGRRDKSAALKELVTQLDVPLDACAYMGDDHNDLGPLSMVALSACPADAVPEVRREAHF
VTQSPGGRGAARELVELCLKASGRWDDAVGLMRGTDRRGTQ
>Mature_200_residues
SANKGVEQAMVTDAPSRLATEELMSRAARVRLLVFDVDGVLTDGGLYYGQDGELMKRFDVKDGHALVMARLSGLPAAILT
ARTSGIVEKRGRELGLAAVFQGRRDKSAALKELVTQLDVPLDACAYMGDDHNDLGPLSMVALSACPADAVPEVRREAHFV
TQSPGGRGAARELVELCLKASGRWDDAVGLMRGTDRRGTQ

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=151, Percent_Identity=29.8013245033113, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI2367202, Length=170, Percent_Identity=40, Blast_Score=128, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 21525; Mature: 21394

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSANKGVEQAMVTDAPSRLATEELMSRAARVRLLVFDVDGVLTDGGLYYGQDGELMKRFD
CCCCCCHHHHHHHCCCHHHHHHHHHHHHHHEEEEEEECCCEEECCCEEECCCCHHHHHCC
VKDGHALVMARLSGLPAAILTARTSGIVEKRGRELGLAAVFQGRRDKSAALKELVTQLDV
CCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHHHHHHCC
PLDACAYMGDDHNDLGPLSMVALSACPADAVPEVRREAHFVTQSPGGRGAARELVELCLK
CHHHHHHCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
ASGRWDDAVGLMRGTDRRGTQ
CCCCCCHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SANKGVEQAMVTDAPSRLATEELMSRAARVRLLVFDVDGVLTDGGLYYGQDGELMKRFD
CCCCCHHHHHHHCCCHHHHHHHHHHHHHHEEEEEEECCCEEECCCEEECCCCHHHHHCC
VKDGHALVMARLSGLPAAILTARTSGIVEKRGRELGLAAVFQGRRDKSAALKELVTQLDV
CCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHHHHHHCC
PLDACAYMGDDHNDLGPLSMVALSACPADAVPEVRREAHFVTQSPGGRGAARELVELCLK
CHHHHHHCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
ASGRWDDAVGLMRGTDRRGTQ
CCCCCCHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]