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The map label for this gene is serB [H]

Identifier: 108757505

GI number: 108757505

Start: 1270126

End: 1271325

Strand: Direct

Name: serB [H]

Synonym: MXAN_1089

Alternate gene names: 108757505

Gene position: 1270126-1271325 (Clockwise)

Preceding gene: 108758493

Following gene: 108761677

Centisome position: 13.9

GC content: 71.17

Gene sequence:

>1200_bases
ATGACTCCGCCCCTGTCCGAAAGCGTGCTCATCACCGTCACCGGGAAGGACCATCCCGGAATCGTCTCGCGCCTCACCGG
CCTGCTGGCGGAAGCTGGCGCCGAGCTGCTCGACGTGGAGCAGGTGGTGGTGCAGGGGCGCCTCACGCTCTGCCTGTTGG
TGCGTCTGCCCCCGGCGAGCGGCACCCTGGAGACGCTGTTGTCCGCCGCGAAGACGCTGGGCGTGGCGCTGGACTTCCAG
GTGGTGGAGGCGCCCGCCACGCCCGCCGCGTCCGCGCACCACGTCGTCACCGCCGTGGGCCGCGCCCTGGGCGCGAGGGA
GCTTCATGCGCTGACGCAGGTGCTCGCGGGGCACGGTGCCAACGTGGAGCGAATCACGCGCCTCAGCGAGCCGCACCTGG
GCTCGGTGGACATCCACATCAGCCTGCCGCCGGGCCAGCCGCCCGACGCGCTCAAGCACGCGCTGCTGGAGCTGTCCATG
CAGTCGGGCGGGTTCGACGTGGCGCTGCAGCGCGAGAGCCTGTTCCGGCGCGGCAAGCGGATGGTCGTCATGGACATGGA
CTCCACGCTCATCCGCATCGAGGTCATCGACGAGCTGGCGCGCGCGCATGGCGTGGGCGAGCAGGTGTCGCGCATCACCG
AGCGCGCCATGCACGGCGAGATGGACTACGACGAATCGCTGCGTCAGCGCGTGGCGTTGCTGCAGGGCCTGGACGCGTCC
GTGGTCCACCAGCTCGCGGCGAACCTGCCGCTGACGGAGGGCGCGGAGACGCTGGTGCGCGTGCTCAAGCGGCTGGGCTA
CCGCACCGCCGTCATCAGCGGCGGCTTCTCCGTGGCGGCCGAGGCGCTGAAGGCGCGGCTGGGCATCGACTTCGCGTACT
CCAACGAGTTGGAGATTCAGGACGGGAAGCTCACCGGCCGCACCGTGGGCCGCATCGTCAACGCGCAGCGCAAGGCGGAG
CTGTTGGAGTCGCTGGCGCAGGCGGAAGGCATCCTGCTGGACCAGGTGGTCGCCGTGGGAGACGGTGCCAACGACTTGCT
GATGCTGGAGCGTGCCGGGCTGGGCATCGCCTTCCGGGCGAAGCCCAAGCTGCGCGCCGCGGCCGACACGTCCATCGCCG
CGGGCGGCCTGGACAGCATCCTCTACCTGCTGGGGCTCACCGGCCGCGAGCTTCTGGAAGCGGGCTCGGGCGCCGGCTGA

Upstream 100 bases:

>100_bases
ATCTCCTCGGACACGCCGAAGGAGTGACGGACGAGCGGCCGGGCCCCGGCGCACTCGGGGCTCGCCGCGCACGTTGGGGG
CTGCCACACTCCGTGGCGCC

Downstream 100 bases:

>100_bases
GGGCGCGCCCTACAGCCGCATCCGCGCCGCCAGTTCGCGCTGCTGGAGCTGGTTCTTCTCCAGCAGCAGCTCGAGCAGCG
CGCGCAGAATCTTGGAGCTC

Product: ACT domain-containing protein/phosphoserine phosphatase SerB

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MTPPLSESVLITVTGKDHPGIVSRLTGLLAEAGAELLDVEQVVVQGRLTLCLLVRLPPASGTLETLLSAAKTLGVALDFQ
VVEAPATPAASAHHVVTAVGRALGARELHALTQVLAGHGANVERITRLSEPHLGSVDIHISLPPGQPPDALKHALLELSM
QSGGFDVALQRESLFRRGKRMVVMDMDSTLIRIEVIDELARAHGVGEQVSRITERAMHGEMDYDESLRQRVALLQGLDAS
VVHQLAANLPLTEGAETLVRVLKRLGYRTAVISGGFSVAAEALKARLGIDFAYSNELEIQDGKLTGRTVGRIVNAQRKAE
LLESLAQAEGILLDQVVAVGDGANDLLMLERAGLGIAFRAKPKLRAAADTSIAAGGLDSILYLLGLTGRELLEAGSGAG

Sequences:

>Translated_399_residues
MTPPLSESVLITVTGKDHPGIVSRLTGLLAEAGAELLDVEQVVVQGRLTLCLLVRLPPASGTLETLLSAAKTLGVALDFQ
VVEAPATPAASAHHVVTAVGRALGARELHALTQVLAGHGANVERITRLSEPHLGSVDIHISLPPGQPPDALKHALLELSM
QSGGFDVALQRESLFRRGKRMVVMDMDSTLIRIEVIDELARAHGVGEQVSRITERAMHGEMDYDESLRQRVALLQGLDAS
VVHQLAANLPLTEGAETLVRVLKRLGYRTAVISGGFSVAAEALKARLGIDFAYSNELEIQDGKLTGRTVGRIVNAQRKAE
LLESLAQAEGILLDQVVAVGDGANDLLMLERAGLGIAFRAKPKLRAAADTSIAAGGLDSILYLLGLTGRELLEAGSGAG
>Mature_398_residues
TPPLSESVLITVTGKDHPGIVSRLTGLLAEAGAELLDVEQVVVQGRLTLCLLVRLPPASGTLETLLSAAKTLGVALDFQV
VEAPATPAASAHHVVTAVGRALGARELHALTQVLAGHGANVERITRLSEPHLGSVDIHISLPPGQPPDALKHALLELSMQ
SGGFDVALQRESLFRRGKRMVVMDMDSTLIRIEVIDELARAHGVGEQVSRITERAMHGEMDYDESLRQRVALLQGLDASV
VHQLAANLPLTEGAETLVRVLKRLGYRTAVISGGFSVAAEALKARLGIDFAYSNELEIQDGKLTGRTVGRIVNAQRKAEL
LESLAQAEGILLDQVVAVGDGANDLLMLERAGLGIAFRAKPKLRAAADTSIAAGGLDSILYLLGLTGRELLEAGSGAG

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=182, Percent_Identity=32.4175824175824, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI1790849, Length=208, Percent_Identity=50.4807692307692, Blast_Score=199, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6321647, Length=259, Percent_Identity=40.9266409266409, Blast_Score=187, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF01842 ACT; PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 42080; Mature: 41949

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPPLSESVLITVTGKDHPGIVSRLTGLLAEAGAELLDVEQVVVQGRLTLCLLVRLPPAS
CCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHCCEEEEEEEECCCCC
GTLETLLSAAKTLGVALDFQVVEAPATPAASAHHVVTAVGRALGARELHALTQVLAGHGA
CHHHHHHHHHHHHCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NVERITRLSEPHLGSVDIHISLPPGQPPDALKHALLELSMQSGGFDVALQRESLFRRGKR
CHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCE
MVVMDMDSTLIRIEVIDELARAHGVGEQVSRITERAMHGEMDYDESLRQRVALLQGLDAS
EEEEECCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHH
VVHQLAANLPLTEGAETLVRVLKRLGYRTAVISGGFSVAAEALKARLGIDFAYSNELEIQ
HHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCEEEECCCEEEE
DGKLTGRTVGRIVNAQRKAELLESLAQAEGILLDQVVAVGDGANDLLMLERAGLGIAFRA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEEEEECCCCEEEEC
KPKLRAAADTSIAAGGLDSILYLLGLTGRELLEAGSGAG
CCCCHHHCCCCHHCCCHHHHHHHHCCCHHHHHHCCCCCC
>Mature Secondary Structure 
TPPLSESVLITVTGKDHPGIVSRLTGLLAEAGAELLDVEQVVVQGRLTLCLLVRLPPAS
CCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHCCEEEEEEEECCCCC
GTLETLLSAAKTLGVALDFQVVEAPATPAASAHHVVTAVGRALGARELHALTQVLAGHGA
CHHHHHHHHHHHHCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NVERITRLSEPHLGSVDIHISLPPGQPPDALKHALLELSMQSGGFDVALQRESLFRRGKR
CHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCE
MVVMDMDSTLIRIEVIDELARAHGVGEQVSRITERAMHGEMDYDESLRQRVALLQGLDAS
EEEEECCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHH
VVHQLAANLPLTEGAETLVRVLKRLGYRTAVISGGFSVAAEALKARLGIDFAYSNELEIQ
HHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCEEEECCCEEEE
DGKLTGRTVGRIVNAQRKAELLESLAQAEGILLDQVVAVGDGANDLLMLERAGLGIAFRA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEEEEECCCCEEEEC
KPKLRAAADTSIAAGGLDSILYLLGLTGRELLEAGSGAG
CCCCHHHCCCCHHCCCHHHHHHHHCCCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA