| Definition | Myxococcus xanthus DK 1622 chromosome, complete genome. |
|---|---|
| Accession | NC_008095 |
| Length | 9,139,763 |
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The map label for this gene is paaF [C]
Identifier: 108757470
GI number: 108757470
Start: 3164957
End: 3165739
Strand: Direct
Name: paaF [C]
Synonym: MXAN_2712
Alternate gene names: 108757470
Gene position: 3164957-3165739 (Clockwise)
Preceding gene: 108761069
Following gene: 108758189
Centisome position: 34.63
GC content: 71.65
Gene sequence:
>783_bases ATGGAAGCCGGAGAAGTCCGCTACGAAGTCCAAGGCACCCAAGCGCTCCTGACCATTGACCGGCCCAAGGCCCGCAACGC CTTGTCCCCGGCGGTGGTGCGCGAGCTGATGGCCGCGCTGGAGCGGGCCGAATCCGACACCTCGGTGCGCGTGGTGGTGC TGACGGGCGCCGGTGAGAAGGTCTTCTGCGCGGGCGGGGACCTGGGAACCCTGGCCGGTGACGAGGGCTTCCTGTCCACG CACGAGGGCCGCCGTTCCTATGGGCGGCTGCTGGCGCGCTTCCAGGAGCTGCGCAAGCCCACCGTGGCGCGCGTCAACGG GCACGCGCTGGCGGGTGGCCTGGGGCTGGTGCTCGCGTGTGACCTGGCCGTCGCCGTGGAGGGCGCGGACCTGGGCACGC CCGAAATCGACGTGGGCCTCTTCCCGATGATGATGATGGCGCTGCTCCAGCGTCACCTGGGCCGCAAGCGTGCGCTGGAG CTGGTGCTCACCGGAGACCGGCTGCCCGCGCGCGAGGCGCTGACGTTGGGGCTGCTCAACCGCGTGGTGCCGGCCGCGGA GCTGGACGCCGCGGTGGGCACGCTCGCGGGAAAGCTGGCGGGAAAGAGCCAGGCGGTGCTGGCGTTGGGGCGCCGTGCCT TCTTCACCGCCGAGGACCTGCCGCTGCCCGCCGCGCTGGAGTACCTGGCCTCGCAGCTGTCTCTGAACGTGCTGGCGGAC GACGCGGGGGAGGGCATCTCCGCGTTCCTGGAGAAGCGTCCCCCGAAGTGGAACGACCGCTGA
Upstream 100 bases:
>100_bases ACGCGCGCGACCCCGACGCCCTGGAGCGGGCGAAGTCGCAGATTGCCGACTCCTTCCTTTACGGCGTCCTCACGGGTGCC CAGGCAGCGGAGGTGTCCGA
Downstream 100 bases:
>100_bases CGCCGGTTACGGCGTGCCCAGCTCGGTGTTGCCGCCCCGGGCGACGCTGGGCGGCAGGTGCGGGAAGAAGTCCAGCTTCA GCAGGCGCTCACCGTCCACC
Product: enoyl-CoA hydratase/isomerase family protein
Products: NA
Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]
Number of amino acids: Translated: 260; Mature: 260
Protein sequence:
>260_residues MEAGEVRYEVQGTQALLTIDRPKARNALSPAVVRELMAALERAESDTSVRVVVLTGAGEKVFCAGGDLGTLAGDEGFLST HEGRRSYGRLLARFQELRKPTVARVNGHALAGGLGLVLACDLAVAVEGADLGTPEIDVGLFPMMMMALLQRHLGRKRALE LVLTGDRLPAREALTLGLLNRVVPAAELDAAVGTLAGKLAGKSQAVLALGRRAFFTAEDLPLPAALEYLASQLSLNVLAD DAGEGISAFLEKRPPKWNDR
Sequences:
>Translated_260_residues MEAGEVRYEVQGTQALLTIDRPKARNALSPAVVRELMAALERAESDTSVRVVVLTGAGEKVFCAGGDLGTLAGDEGFLST HEGRRSYGRLLARFQELRKPTVARVNGHALAGGLGLVLACDLAVAVEGADLGTPEIDVGLFPMMMMALLQRHLGRKRALE LVLTGDRLPAREALTLGLLNRVVPAAELDAAVGTLAGKLAGKSQAVLALGRRAFFTAEDLPLPAALEYLASQLSLNVLAD DAGEGISAFLEKRPPKWNDR >Mature_260_residues MEAGEVRYEVQGTQALLTIDRPKARNALSPAVVRELMAALERAESDTSVRVVVLTGAGEKVFCAGGDLGTLAGDEGFLST HEGRRSYGRLLARFQELRKPTVARVNGHALAGGLGLVLACDLAVAVEGADLGTPEIDVGLFPMMMMALLQRHLGRKRALE LVLTGDRLPAREALTLGLLNRVVPAAELDAAVGTLAGKLAGKSQAVLALGRRAFFTAEDLPLPAALEYLASQLSLNVLAD DAGEGISAFLEKRPPKWNDR
Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]
Homologues:
Organism=Homo sapiens, GI31542718, Length=246, Percent_Identity=36.1788617886179, Blast_Score=140, Evalue=1e-33, Organism=Homo sapiens, GI194097323, Length=253, Percent_Identity=34.3873517786561, Blast_Score=132, Evalue=3e-31, Organism=Homo sapiens, GI37594471, Length=194, Percent_Identity=29.8969072164948, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI37594469, Length=194, Percent_Identity=29.8969072164948, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI68989263, Length=179, Percent_Identity=34.0782122905028, Blast_Score=88, Evalue=7e-18, Organism=Homo sapiens, GI70995211, Length=254, Percent_Identity=30.7086614173228, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI4757968, Length=207, Percent_Identity=31.4009661835749, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI49355787, Length=207, Percent_Identity=31.4009661835749, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI4757966, Length=206, Percent_Identity=30.0970873786408, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI51538581, Length=206, Percent_Identity=30.0970873786408, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI25453481, Length=206, Percent_Identity=30.0970873786408, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI51538573, Length=206, Percent_Identity=30.0970873786408, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI20127408, Length=183, Percent_Identity=27.8688524590164, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI221307494, Length=209, Percent_Identity=30.622009569378, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI221136756, Length=209, Percent_Identity=30.622009569378, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI221136753, Length=209, Percent_Identity=30.622009569378, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI116235487, Length=222, Percent_Identity=30.1801801801802, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI4502327, Length=251, Percent_Identity=28.6852589641434, Blast_Score=69, Evalue=5e-12, Organism=Escherichia coli, GI1787659, Length=247, Percent_Identity=38.0566801619433, Blast_Score=136, Evalue=1e-33, Organism=Escherichia coli, GI1788597, Length=262, Percent_Identity=33.969465648855, Blast_Score=119, Evalue=2e-28, Organism=Escherichia coli, GI221142681, Length=255, Percent_Identity=36.078431372549, Blast_Score=118, Evalue=3e-28, Organism=Escherichia coli, GI1787660, Length=245, Percent_Identity=33.469387755102, Blast_Score=85, Evalue=4e-18, Organism=Escherichia coli, GI87082183, Length=248, Percent_Identity=26.6129032258064, Blast_Score=82, Evalue=2e-17, Organism=Escherichia coli, GI1788682, Length=188, Percent_Identity=32.9787234042553, Blast_Score=78, Evalue=5e-16, Organism=Escherichia coli, GI1790281, Length=179, Percent_Identity=31.2849162011173, Blast_Score=69, Evalue=3e-13, Organism=Caenorhabditis elegans, GI25145438, Length=244, Percent_Identity=37.2950819672131, Blast_Score=139, Evalue=2e-33, Organism=Caenorhabditis elegans, GI17554946, Length=247, Percent_Identity=34.0080971659919, Blast_Score=138, Evalue=4e-33, Organism=Caenorhabditis elegans, GI17540306, Length=247, Percent_Identity=32.3886639676113, Blast_Score=114, Evalue=5e-26, Organism=Caenorhabditis elegans, GI25144160, Length=194, Percent_Identity=32.9896907216495, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI25144157, Length=194, Percent_Identity=32.9896907216495, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17560910, Length=253, Percent_Identity=28.8537549407115, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17534483, Length=250, Percent_Identity=29.2, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17540714, Length=181, Percent_Identity=32.0441988950276, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI17549921, Length=195, Percent_Identity=29.2307692307692, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17558304, Length=181, Percent_Identity=30.939226519337, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI17508951, Length=193, Percent_Identity=31.0880829015544, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17508953, Length=193, Percent_Identity=31.0880829015544, Blast_Score=77, Evalue=6e-15, Organism=Caenorhabditis elegans, GI25144276, Length=193, Percent_Identity=31.0880829015544, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI17536985, Length=262, Percent_Identity=24.0458015267176, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17535521, Length=251, Percent_Identity=23.1075697211155, Blast_Score=69, Evalue=3e-12, Organism=Saccharomyces cerevisiae, GI6320241, Length=251, Percent_Identity=28.6852589641434, Blast_Score=90, Evalue=3e-19, Organism=Drosophila melanogaster, GI20129971, Length=261, Percent_Identity=34.0996168582375, Blast_Score=139, Evalue=3e-33, Organism=Drosophila melanogaster, GI24653477, Length=261, Percent_Identity=34.0996168582375, Blast_Score=139, Evalue=3e-33, Organism=Drosophila melanogaster, GI19922422, Length=244, Percent_Identity=29.5081967213115, Blast_Score=125, Evalue=4e-29, Organism=Drosophila melanogaster, GI21357171, Length=210, Percent_Identity=33.3333333333333, Blast_Score=95, Evalue=6e-20, Organism=Drosophila melanogaster, GI24653139, Length=249, Percent_Identity=31.7269076305221, Blast_Score=88, Evalue=7e-18, Organism=Drosophila melanogaster, GI24654903, Length=193, Percent_Identity=29.0155440414508, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI24650670, Length=253, Percent_Identity=32.0158102766798, Blast_Score=82, Evalue=2e-16, Organism=Drosophila melanogaster, GI28571730, Length=250, Percent_Identity=26.8, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI28571729, Length=250, Percent_Identity=26.8, Blast_Score=74, Evalue=1e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR014748 - InterPro: IPR001753 - InterPro: IPR018376 [H]
Pfam domain/function: PF00378 ECH [H]
EC number: =4.2.1.116 [H]
Molecular weight: Translated: 27544; Mature: 27544
Theoretical pI: Translated: 6.30; Mature: 6.30
Prosite motif: PS00166 ENOYL_COA_HYDRATASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MEAGEVRYEVQGTQALLTIDRPKARNALSPAVVRELMAALERAESDTSVRVVVLTGAGEK CCCCCEEEEEECCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCE VFCAGGDLGTLAGDEGFLSTHEGRRSYGRLLARFQELRKPTVARVNGHALAGGLGLVLAC EEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHH DLAVAVEGADLGTPEIDVGLFPMMMMALLQRHLGRKRALELVLTGDRLPAREALTLGLLN HHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHCHHHEEEEEEECCCCCHHHHHHHHHHH RVVPAAELDAAVGTLAGKLAGKSQAVLALGRRAFFTAEDLPLPAALEYLASQLSLNVLAD HHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHEEEEC DAGEGISAFLEKRPPKWNDR CCCCHHHHHHHCCCCCCCCC >Mature Secondary Structure MEAGEVRYEVQGTQALLTIDRPKARNALSPAVVRELMAALERAESDTSVRVVVLTGAGEK CCCCCEEEEEECCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCE VFCAGGDLGTLAGDEGFLSTHEGRRSYGRLLARFQELRKPTVARVNGHALAGGLGLVLAC EEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHH DLAVAVEGADLGTPEIDVGLFPMMMMALLQRHLGRKRALELVLTGDRLPAREALTLGLLN HHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHCHHHEEEEEEECCCCCHHHHHHHHHHH RVVPAAELDAAVGTLAGKLAGKSQAVLALGRRAFFTAEDLPLPAALEYLASQLSLNVLAD HHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHEEEEC DAGEGISAFLEKRPPKWNDR CCCCHHHHHHHCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA