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The map label for this gene is aadA [H]

Identifier: 108757401

GI number: 108757401

Start: 2013057

End: 2013875

Strand: Reverse

Name: aadA [H]

Synonym: MXAN_1698

Alternate gene names: 108757401

Gene position: 2013875-2013057 (Counterclockwise)

Preceding gene: 108757884

Following gene: 108763092

Centisome position: 22.03

GC content: 61.54

Gene sequence:

>819_bases
ATGAACGCATCCGTACCGACTGAAATCACGCACCAGGTTTCAAGCGCCTGCTCAGTGATTGGCCGTCACCTGGCCAGTTC
GCTGCAGGCCATACACCTCTTCGGCTCGGCAGTTGATGGAGGGCTGAAACCACACAGCGACATCGATTTGCTGGTAACCG
TCAGCGCCCCATTGACCGAAGCCGTTCGACACGCGCTGCTCAAGGAGCTGTTGTCGGTCTCGACATGGCCAATGACGCGT
GAATCGCTCCGCCCTCTCGAAGTGACCGTTGTCGTCCGGGATGCGGTCGTCCCTTGGCGCTACCCGCCGTCACGCGAACT
TCAATTCGGGGAATGGTTGCGCGGAGAAATGGAAGCCGGCCACGTCCAGCCCGCCATCGTGGACCCCGACCTGACAATCT
TGCTGGCGAAGGCAAGGAGACACAGCATCTGCCTGTTGGGCGAGCCAGCAACCGACCTCTTCGACCCCGTACCCCGGACC
GATCTGGCGAGAGCGTTCTACGACACCGCTCTCCAATGGAACGAACCTGCGGACTGGCGTGGGGACGAAAGGACCGTGGT
GCTTGCGCTGGCTCGCATCTGGTTCAGCCTGTCGACGGGGGGAATCGCCCCCAAAGACGTTGCGGCCCAGTGGGTCATTG
AACGCCTGCCGGATGAACATCAAAGTATCATGCGCAGTGCGCGGGCGTCTTACCTTGGAGAGACGCAGGACGATTTGGCA
CGGAGAGGCCCGGAAGTCGCCGCGTTCGTGCACTGTGCCAGGACGGCCATCGAACGAATGTACTTGGAATGGCAGTCCGG
CAATCCGGCGGCTCGCTGA

Upstream 100 bases:

>100_bases
TGACGACAGGGGAAGCCTCGTCCCCTGTTCTTTCAACCAGGGAGCACATGGGGCATCTTCCGAATCTGTAGAGCCAAGGA
CCCTGCCAGTGGTGGCCGAC

Downstream 100 bases:

>100_bases
ACCTGTGCCTACCTGAAATTCGGTCGCTGCGTCCTGTGCGCGTCAAGGCGAGTGGGCGCGGCGGGCGAGCACGGCCTGGC
CGCCCGCAGGCATCTCACCA

Product: aminoglycoside resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MNASVPTEITHQVSSACSVIGRHLASSLQAIHLFGSAVDGGLKPHSDIDLLVTVSAPLTEAVRHALLKELLSVSTWPMTR
ESLRPLEVTVVVRDAVVPWRYPPSRELQFGEWLRGEMEAGHVQPAIVDPDLTILLAKARRHSICLLGEPATDLFDPVPRT
DLARAFYDTALQWNEPADWRGDERTVVLALARIWFSLSTGGIAPKDVAAQWVIERLPDEHQSIMRSARASYLGETQDDLA
RRGPEVAAFVHCARTAIERMYLEWQSGNPAAR

Sequences:

>Translated_272_residues
MNASVPTEITHQVSSACSVIGRHLASSLQAIHLFGSAVDGGLKPHSDIDLLVTVSAPLTEAVRHALLKELLSVSTWPMTR
ESLRPLEVTVVVRDAVVPWRYPPSRELQFGEWLRGEMEAGHVQPAIVDPDLTILLAKARRHSICLLGEPATDLFDPVPRT
DLARAFYDTALQWNEPADWRGDERTVVLALARIWFSLSTGGIAPKDVAAQWVIERLPDEHQSIMRSARASYLGETQDDLA
RRGPEVAAFVHCARTAIERMYLEWQSGNPAAR
>Mature_272_residues
MNASVPTEITHQVSSACSVIGRHLASSLQAIHLFGSAVDGGLKPHSDIDLLVTVSAPLTEAVRHALLKELLSVSTWPMTR
ESLRPLEVTVVVRDAVVPWRYPPSRELQFGEWLRGEMEAGHVQPAIVDPDLTILLAKARRHSICLLGEPATDLFDPVPRT
DLARAFYDTALQWNEPADWRGDERTVVLALARIWFSLSTGGIAPKDVAAQWVIERLPDEHQSIMRSARASYLGETQDDLA
RRGPEVAAFVHCARTAIERMYLEWQSGNPAAR

Specific function: Mediates bacterial resistance to the antibiotics streptomycin and spectomycin [H]

COG id: COG1708

COG function: function code R; Predicted nucleotidyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002934 [H]

Pfam domain/function: PF01909 NTP_transf_2 [H]

EC number: =2.7.7.47 [H]

Molecular weight: Translated: 30122; Mature: 30122

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNASVPTEITHQVSSACSVIGRHLASSLQAIHLFGSAVDGGLKPHSDIDLLVTVSAPLTE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHH
AVRHALLKELLSVSTWPMTRESLRPLEVTVVVRDAVVPWRYPPSRELQFGEWLRGEMEAG
HHHHHHHHHHHHHCCCCCCHHHCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHCCCCCC
HVQPAIVDPDLTILLAKARRHSICLLGEPATDLFDPVPRTDLARAFYDTALQWNEPADWR
CCCCEEECCCHHHHEEHHCCCCEEEECCCCHHHHCCCCCHHHHHHHHHHHHCCCCCCCCC
GDERTVVLALARIWFSLSTGGIAPKDVAAQWVIERLPDEHQSIMRSARASYLGETQDDLA
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHH
RRGPEVAAFVHCARTAIERMYLEWQSGNPAAR
HCCCHHHHHHHHHHHHHHHHHHEECCCCCCCC
>Mature Secondary Structure
MNASVPTEITHQVSSACSVIGRHLASSLQAIHLFGSAVDGGLKPHSDIDLLVTVSAPLTE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHH
AVRHALLKELLSVSTWPMTRESLRPLEVTVVVRDAVVPWRYPPSRELQFGEWLRGEMEAG
HHHHHHHHHHHHHCCCCCCHHHCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHCCCCCC
HVQPAIVDPDLTILLAKARRHSICLLGEPATDLFDPVPRTDLARAFYDTALQWNEPADWR
CCCCEEECCCHHHHEEHHCCCCEEEECCCCHHHHCCCCCHHHHHHHHHHHHCCCCCCCCC
GDERTVVLALARIWFSLSTGGIAPKDVAAQWVIERLPDEHQSIMRSARASYLGETQDDLA
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHH
RRGPEVAAFVHCARTAIERMYLEWQSGNPAAR
HCCCHHHHHHHHHHHHHHHHHHEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3054482; 2997737; 2986186; 3037494; 2821509; 2823258; 2188588 [H]