Click here to switch to the map view.

The map label for this gene is prpC [H]

Identifier: 108757368

GI number: 108757368

Start: 5403392

End: 5404666

Strand: Reverse

Name: prpC [H]

Synonym: MXAN_4398

Alternate gene names: 108757368

Gene position: 5404666-5403392 (Counterclockwise)

Preceding gene: 108759176

Following gene: 108763178

Centisome position: 59.13

GC content: 67.61

Gene sequence:

>1275_bases
GTGGCCTTGACCACAGAAGCTTTTGGACTGACCGACGTCGGCCGCAGGCGGCAGCACAACGAAGACGCGATGCTGGTGGA
TGCGGCACTCGGTCTCTACGTGGTGGCTGACGGCATGGGCGGTCACGCGGCCGGCGAGGTCGCGAGCAACCGGGCCACGG
AGGTCGTCAAGCAGCACATCTCCGCCAACCGCCATCTGTTGAAGGACCTGGGCATCAACCCGACGCCGGACAGCCGCTCC
GCGGCGGCGGCGCTCGTCGAGGTGGCCGTCCAGCGCGCGTGCGCGGACATCTACCGGACGGCGATGTCGGACGCGACCAA
GCGCGGCATGGGCACGACGTTCGTGTGCCTCGCGGTAGGCGGCAACAAAGGCGTCATCGGCCATGTGGGTGACAGCCGTG
TCTACCTGGTGCGGCATGGCCAGTGTCACCGGCTGACGGAGGACCACACGCTGGTCGCCGCGCAGCTCAAGGCCGGCACG
ATTACCAAGGACCAGGCCGCCAACTCGCAGTACCGCAACGTGATTACCCGCGCGGTGGGCATCCAGGAGTCCGTCCAGGT
CGACACGCTCATCGTGGACCTGGTGCCCGGGGACATGTTCATCCTCTGCTCGGACGGCCTGCACGGCTATGTCGAGGACG
AGGAGGTCCTTCCGCTCATCGCCGGCATCGCGCCCGCGGACCTGCCCAAGCGCTTCATCGACGTCGCCAACGAGCGCGGT
GGCAAGGACAACATCACCGCGGTGGTGGTGAAGGTCGCGGGCGAAGGCTCCAGCGTCAGCGAGGAGTCGAGCGAAGCGCA
GTCGCGCATGGAGGCGCTGCGCAAGATTCCGCTCTTCCGTCACCTCACCTACAAGGAACAGACGGCGGTGCTGTCCATCG
CGACCACGCGCACGTATCCCGCGGGGCGCGAAATCGTGGTGGAGGGGCAGCCGGGCGAGGAGCTCTTCGTCGTCATCCGG
GGCCGGGTGGCCATCGAGAAGAACGGCGTGGAGATCGCCGAGCTGCGCGCGGGTGGCCACTTCGGAGAGATGGGGCTCAT
CGACAACGCGCCGCGTTCAGCGACGGTGCGAGCGACGGAGCCCACGCGCACCATGGTCATCTCGCGGCCGGACCTGATGG
GCCTGATGAAGCGCGAGTCCATCCTCGCGGTGAAGATGCTCTGGAGCTTCGTCCAGGTGCTCAGCGACCGGCTTCGCGCC
ACCAACTCGGAGCTCAGCGAGGCACGGCAGGAACTGGCCGTGGCCCAGGCGATTGCTCCGTTCGCCGAGGAGTAG

Upstream 100 bases:

>100_bases
CGGATGCTTGCCGTGAGGATGGCTCCCTGAGCCTTGCCACGTCTTCGTGGGCCTGCGTAACGTGCGGAGTCGCCCTCTGT
CACACACGGGAGTGTTCGCG

Downstream 100 bases:

>100_bases
GAGGACGCGTCATGGCCCCTCGTCGACCGAAGCAGCTTCGTCCGGAATCCCAAGCACGTCAGACGTCCCAGGTACGTTCG
CGCCGTTCCGTTGTCGGAGG

Product: protein phosphatase/cyclic nucleotide-binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MALTTEAFGLTDVGRRRQHNEDAMLVDAALGLYVVADGMGGHAAGEVASNRATEVVKQHISANRHLLKDLGINPTPDSRS
AAAALVEVAVQRACADIYRTAMSDATKRGMGTTFVCLAVGGNKGVIGHVGDSRVYLVRHGQCHRLTEDHTLVAAQLKAGT
ITKDQAANSQYRNVITRAVGIQESVQVDTLIVDLVPGDMFILCSDGLHGYVEDEEVLPLIAGIAPADLPKRFIDVANERG
GKDNITAVVVKVAGEGSSVSEESSEAQSRMEALRKIPLFRHLTYKEQTAVLSIATTRTYPAGREIVVEGQPGEELFVVIR
GRVAIEKNGVEIAELRAGGHFGEMGLIDNAPRSATVRATEPTRTMVISRPDLMGLMKRESILAVKMLWSFVQVLSDRLRA
TNSELSEARQELAVAQAIAPFAEE

Sequences:

>Translated_424_residues
MALTTEAFGLTDVGRRRQHNEDAMLVDAALGLYVVADGMGGHAAGEVASNRATEVVKQHISANRHLLKDLGINPTPDSRS
AAAALVEVAVQRACADIYRTAMSDATKRGMGTTFVCLAVGGNKGVIGHVGDSRVYLVRHGQCHRLTEDHTLVAAQLKAGT
ITKDQAANSQYRNVITRAVGIQESVQVDTLIVDLVPGDMFILCSDGLHGYVEDEEVLPLIAGIAPADLPKRFIDVANERG
GKDNITAVVVKVAGEGSSVSEESSEAQSRMEALRKIPLFRHLTYKEQTAVLSIATTRTYPAGREIVVEGQPGEELFVVIR
GRVAIEKNGVEIAELRAGGHFGEMGLIDNAPRSATVRATEPTRTMVISRPDLMGLMKRESILAVKMLWSFVQVLSDRLRA
TNSELSEARQELAVAQAIAPFAEE
>Mature_423_residues
ALTTEAFGLTDVGRRRQHNEDAMLVDAALGLYVVADGMGGHAAGEVASNRATEVVKQHISANRHLLKDLGINPTPDSRSA
AAALVEVAVQRACADIYRTAMSDATKRGMGTTFVCLAVGGNKGVIGHVGDSRVYLVRHGQCHRLTEDHTLVAAQLKAGTI
TKDQAANSQYRNVITRAVGIQESVQVDTLIVDLVPGDMFILCSDGLHGYVEDEEVLPLIAGIAPADLPKRFIDVANERGG
KDNITAVVVKVAGEGSSVSEESSEAQSRMEALRKIPLFRHLTYKEQTAVLSIATTRTYPAGREIVVEGQPGEELFVVIRG
RVAIEKNGVEIAELRAGGHFGEMGLIDNAPRSATVRATEPTRTMVISRPDLMGLMKRESILAVKMLWSFVQVLSDRLRAT
NSELSEARQELAVAQAIAPFAEE

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 45597; Mature: 45465

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS00888 CNMP_BINDING_1 ; PS00889 CNMP_BINDING_2 ; PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTTEAFGLTDVGRRRQHNEDAMLVDAALGLYVVADGMGGHAAGEVASNRATEVVKQHI
CCEECCCCCCHHHHHHHCCCCCCEEEEHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHH
SANRHLLKDLGINPTPDSRSAAAALVEVAVQRACADIYRTAMSDATKRGMGTTFVCLAVG
HCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
GNKGVIGHVGDSRVYLVRHGQCHRLTEDHTLVAAQLKAGTITKDQAANSQYRNVITRAVG
CCCCEEEECCCCEEEEEECCCCCCCCCCCEEEEEEECCCCCCCHHHCCHHHHHHHHHHHC
IQESVQVDTLIVDLVPGDMFILCSDGLHGYVEDEEVLPLIAGIAPADLPKRFIDVANERG
CCCCCEEEEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCC
GKDNITAVVVKVAGEGSSVSEESSEAQSRMEALRKIPLFRHLTYKEQTAVLSIATTRTYP
CCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCEEEEEEEEECCCC
AGREIVVEGQPGEELFVVIRGRVAIEKNGVEIAELRAGGHFGEMGLIDNAPRSATVRATE
CCCEEEEECCCCCEEEEEEECEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCEEEECC
PTRTMVISRPDLMGLMKRESILAVKMLWSFVQVLSDRLRATNSELSEARQELAVAQAIAP
CCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
FAEE
HCCC
>Mature Secondary Structure 
ALTTEAFGLTDVGRRRQHNEDAMLVDAALGLYVVADGMGGHAAGEVASNRATEVVKQHI
CEECCCCCCHHHHHHHCCCCCCEEEEHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHH
SANRHLLKDLGINPTPDSRSAAAALVEVAVQRACADIYRTAMSDATKRGMGTTFVCLAVG
HCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
GNKGVIGHVGDSRVYLVRHGQCHRLTEDHTLVAAQLKAGTITKDQAANSQYRNVITRAVG
CCCCEEEECCCCEEEEEECCCCCCCCCCCEEEEEEECCCCCCCHHHCCHHHHHHHHHHHC
IQESVQVDTLIVDLVPGDMFILCSDGLHGYVEDEEVLPLIAGIAPADLPKRFIDVANERG
CCCCCEEEEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCC
GKDNITAVVVKVAGEGSSVSEESSEAQSRMEALRKIPLFRHLTYKEQTAVLSIATTRTYP
CCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCEEEEEEEEECCCC
AGREIVVEGQPGEELFVVIRGRVAIEKNGVEIAELRAGGHFGEMGLIDNAPRSATVRATE
CCCEEEEECCCCCEEEEEEECEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCEEEECC
PTRTMVISRPDLMGLMKRESILAVKMLWSFVQVLSDRLRATNSELSEARQELAVAQAIAP
CCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
FAEE
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]