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The map label for this gene is muT4 [H]

Identifier: 108757311

GI number: 108757311

Start: 6123336

End: 6123815

Strand: Reverse

Name: muT4 [H]

Synonym: MXAN_4891

Alternate gene names: 108757311

Gene position: 6123815-6123336 (Counterclockwise)

Preceding gene: 108757020

Following gene: 108757643

Centisome position: 67.0

GC content: 69.38

Gene sequence:

>480_bases
ATGCCACGCGAGGCGTCCGCAGGAGGTGTCGTCATCCGGGAGAGCGCCGGCCACTGGGAGGTGGTCGTCATCCGTCCCCA
TGGCCGCACCTTGTGGGCGCTCCCCAAGGGGCACGTGGACCCAGGTGAGTCGCCGGAGCAGACGGCCAGCCGCGAGGTGC
GTGAGGAGACGGGGCTGTCCGTGTCGCTCATGGCCCCGCTGGGCGAGATTCGCTACGTGTACCAGTTCCGCGGACAGCGC
ATCTTCAAGCGCGTCCACTTCTTCCTGTTCCGCTATCAGGAGGGGGAGCTGGGGCCGCTGCCGGGACCGCGCATCGAGGT
GGACGAGGTGCGCTGGGTGCCGGTGGTCCAACTGGTGCCACTGCTGGGCTACAAAGGAGAGAAGGCCGTTGCCTCGCGGG
CGGTGCGCTGGTTGCGCTCCCAGGGCCTGCTCCCCGAAGCCCCCTCCCCGGTGAGCATTGCCGGGAAGGAAGGGGGCTGA

Upstream 100 bases:

>100_bases
TGCGTTACGCCTACCGGCTGGGGGCGGAGGCCAAGCTTCGCCATTTCGCGCATGGCGGGTGAGCACCTTTCTCCTTCCGT
ATCGGGTAGGGTGGGCGGGT

Downstream 100 bases:

>100_bases
AGGGAACCGCGGGGACTACTTGGGCTCGTCGCCCGTGTACTTGCCGGACAGCGCCTCGCGCACGTCACGGTCGAACTTCA
CGCGGCCGGTGGCCACCTCG

Product: NUDIX family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MPREASAGGVVIRESAGHWEVVVIRPHGRTLWALPKGHVDPGESPEQTASREVREETGLSVSLMAPLGEIRYVYQFRGQR
IFKRVHFFLFRYQEGELGPLPGPRIEVDEVRWVPVVQLVPLLGYKGEKAVASRAVRWLRSQGLLPEAPSPVSIAGKEGG

Sequences:

>Translated_159_residues
MPREASAGGVVIRESAGHWEVVVIRPHGRTLWALPKGHVDPGESPEQTASREVREETGLSVSLMAPLGEIRYVYQFRGQR
IFKRVHFFLFRYQEGELGPLPGPRIEVDEVRWVPVVQLVPLLGYKGEKAVASRAVRWLRSQGLLPEAPSPVSIAGKEGG
>Mature_158_residues
PREASAGGVVIRESAGHWEVVVIRPHGRTLWALPKGHVDPGESPEQTASREVREETGLSVSLMAPLGEIRYVYQFRGQRI
FKRVHFFLFRYQEGELGPLPGPRIEVDEVRWVPVVQLVPLLGYKGEKAVASRAVRWLRSQGLLPEAPSPVSIAGKEGG

Specific function: May be involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8- oxoguanine, 8-oxo-dGTP) from DNA and the nucleotide pool. In vitro has dATPase rather than 8-oxo-dGTPase activity [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 17657; Mature: 17525

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPREASAGGVVIRESAGHWEVVVIRPHGRTLWALPKGHVDPGESPEQTASREVREETGLS
CCCCCCCCCEEEEECCCCEEEEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCE
VSLMAPLGEIRYVYQFRGQRIFKRVHFFLFRYQEGELGPLPGPRIEVDEVRWVPVVQLVP
EEEECCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCEEECCCCEEHHHHHHH
LLGYKGEKAVASRAVRWLRSQGLLPEAPSPVSIAGKEGG
HHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCC
>Mature Secondary Structure 
PREASAGGVVIRESAGHWEVVVIRPHGRTLWALPKGHVDPGESPEQTASREVREETGLS
CCCCCCCCEEEEECCCCEEEEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCE
VSLMAPLGEIRYVYQFRGQRIFKRVHFFLFRYQEGELGPLPGPRIEVDEVRWVPVVQLVP
EEEECCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCEEECCCCEEHHHHHHH
LLGYKGEKAVASRAVRWLRSQGLLPEAPSPVSIAGKEGG
HHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]