| Definition | Myxococcus xanthus DK 1622 chromosome, complete genome. |
|---|---|
| Accession | NC_008095 |
| Length | 9,139,763 |
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The map label for this gene is pknB [H]
Identifier: 108757303
GI number: 108757303
Start: 2216216
End: 2217388
Strand: Direct
Name: pknB [H]
Synonym: MXAN_1892
Alternate gene names: 108757303
Gene position: 2216216-2217388 (Clockwise)
Preceding gene: 108763041
Following gene: 108757062
Centisome position: 24.25
GC content: 67.09
Gene sequence:
>1173_bases ATGACGAAGCGTTCGGAAGATGAAGTGTCGACGGAGGAGTTCCCGCCCCGCCCCCCCACACCGCCCAGCCCCAGCTCGCC GCACTTCCTCTTCGTCGTGGATGACGTTCGCTACGAGGCGGTGGGGGAGCTTGAGGTGCGGTCGAATGGCGAGAAGCTCC TGAAGGCGGAGCGGCGAGTGGCGGATGGAGTCCTGGCCGGCCCCTGCCTGGTTCGCCGGATTGCCACCCCCTCCACGTAC ATGATGCGCACGCGGCTGATTGAAGAGGTGCAGTTGGCTTTCCGGCTCAACCACCCCAACATCGCTCAAGTCTTCCACAT GCAGGTGGATGAGGAGGCGGACGCCCCCTTCGCAGTCATGGAGTACGTGGGTGGGCCCTCGCTGGAGACGCTGGTGACTG CGGCGTTGGTGCGAGGCAAGCCCCTCTCGGAGGGATTTGCCTTGTACGTCGGGGCGGAGGTGGCGGACGCGCTGCACTAC GCGCACACGCTGACGTCGGAGGAGGGCGTGCCCCTGGGCATTGTCCACCGCGACGTGAGTCCCAGGAGGCTTGCACTGGG GCCGCATGGAGAGGTGAAGGTGCTGGACTTCGGCGCGGCGTACTCGCTGATGGTGGGGCGGGAGGAGTCGCCGGAGAATC TGCTGCGGGGGGACGTGGCCTACGCCTCTCCGGAGTACCTGCGCAAGGAAGGGCTGACGCCGCGCTCCGACGTCTTCAGC CTGGGGGTGTTGCTGGTGGAAGTCCTCACGAGCAAGCACCTCTTCGAGGTGCATGACGTCCCGGTGGTGGCGTCGAAGGA GACGCGGTTTGTCACGGAGTCGCCGCCCACTTTGCCGCTGCAGCAGATGCAGGCCCTCATGGAGACATTCACTCCGGATG TCGTCGAGAAGGCGGTGGCCCACCTCAGTGAGGACCTCAAGGCGGTGTTGCACACGGCCCTGCGCCTCAACCCCGAGGAG CGCTTCGCGACAGCGGCGGACATGCGGGATGCGCTGCGTGGTGTCGCCCACGCCCAGCTCCGTGCGCCCTATGGGCGCGC GGAGGCCGCCAAGGAGGCCGCCCTCGTGGTGTCCGAAGGCGGGGTGCTGCGGGACCAGGTAGAGTTCGGCGAGGCCGGCC TCTACCCGGATGGGCTGGAGAAGCACGAGCTGGGACTCCCGAAGAAGGAGTAG
Upstream 100 bases:
>100_bases TCGAGTCAACTGGACCTAGCAAGCTTCGGGAGAGTTGCCCGCTACGGCGAATGTCGGTGACGGTGGGGCCGCGCCCCTTC TTTCAGGAGGATTCACAGCC
Downstream 100 bases:
>100_bases GCCGCCGATGCTCTGCTTTCGCCTACTGCGCAATGGCCGGCACGTCGCAACCGCGGGGGTGTCGGGCTTCGGTGTCGTCT CCACCATTCTGACGTGGGTG
Product: putative serine/threonine protein kinase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 390; Mature: 389
Protein sequence:
>390_residues MTKRSEDEVSTEEFPPRPPTPPSPSSPHFLFVVDDVRYEAVGELEVRSNGEKLLKAERRVADGVLAGPCLVRRIATPSTY MMRTRLIEEVQLAFRLNHPNIAQVFHMQVDEEADAPFAVMEYVGGPSLETLVTAALVRGKPLSEGFALYVGAEVADALHY AHTLTSEEGVPLGIVHRDVSPRRLALGPHGEVKVLDFGAAYSLMVGREESPENLLRGDVAYASPEYLRKEGLTPRSDVFS LGVLLVEVLTSKHLFEVHDVPVVASKETRFVTESPPTLPLQQMQALMETFTPDVVEKAVAHLSEDLKAVLHTALRLNPEE RFATAADMRDALRGVAHAQLRAPYGRAEAAKEAALVVSEGGVLRDQVEFGEAGLYPDGLEKHELGLPKKE
Sequences:
>Translated_390_residues MTKRSEDEVSTEEFPPRPPTPPSPSSPHFLFVVDDVRYEAVGELEVRSNGEKLLKAERRVADGVLAGPCLVRRIATPSTY MMRTRLIEEVQLAFRLNHPNIAQVFHMQVDEEADAPFAVMEYVGGPSLETLVTAALVRGKPLSEGFALYVGAEVADALHY AHTLTSEEGVPLGIVHRDVSPRRLALGPHGEVKVLDFGAAYSLMVGREESPENLLRGDVAYASPEYLRKEGLTPRSDVFS LGVLLVEVLTSKHLFEVHDVPVVASKETRFVTESPPTLPLQQMQALMETFTPDVVEKAVAHLSEDLKAVLHTALRLNPEE RFATAADMRDALRGVAHAQLRAPYGRAEAAKEAALVVSEGGVLRDQVEFGEAGLYPDGLEKHELGLPKKE >Mature_389_residues TKRSEDEVSTEEFPPRPPTPPSPSSPHFLFVVDDVRYEAVGELEVRSNGEKLLKAERRVADGVLAGPCLVRRIATPSTYM MRTRLIEEVQLAFRLNHPNIAQVFHMQVDEEADAPFAVMEYVGGPSLETLVTAALVRGKPLSEGFALYVGAEVADALHYA HTLTSEEGVPLGIVHRDVSPRRLALGPHGEVKVLDFGAAYSLMVGREESPENLLRGDVAYASPEYLRKEGLTPRSDVFSL GVLLVEVLTSKHLFEVHDVPVVASKETRFVTESPPTLPLQQMQALMETFTPDVVEKAVAHLSEDLKAVLHTALRLNPEER FATAADMRDALRGVAHAQLRAPYGRAEAAKEAALVVSEGGVLRDQVEFGEAGLYPDGLEKHELGLPKKE
Specific function: Unknown
COG id: COG0515
COG function: function code RTKL; Serine/threonine protein kinase
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 1 protein kinase domain [H]
Homologues:
Organism=Homo sapiens, GI4505373, Length=163, Percent_Identity=31.9018404907975, Blast_Score=79, Evalue=7e-15, Organism=Homo sapiens, GI33636756, Length=255, Percent_Identity=25.4901960784314, Blast_Score=75, Evalue=1e-13, Organism=Homo sapiens, GI190886457, Length=164, Percent_Identity=27.4390243902439, Blast_Score=71, Evalue=2e-12, Organism=Homo sapiens, GI42794769, Length=164, Percent_Identity=27.4390243902439, Blast_Score=71, Evalue=2e-12, Organism=Homo sapiens, GI32483399, Length=164, Percent_Identity=27.4390243902439, Blast_Score=71, Evalue=2e-12, Organism=Homo sapiens, GI189491755, Length=164, Percent_Identity=27.4390243902439, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI189491757, Length=164, Percent_Identity=27.4390243902439, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI189491759, Length=164, Percent_Identity=27.4390243902439, Blast_Score=70, Evalue=4e-12, Organism=Homo sapiens, GI189491753, Length=164, Percent_Identity=27.4390243902439, Blast_Score=70, Evalue=4e-12, Organism=Homo sapiens, GI189491751, Length=164, Percent_Identity=27.4390243902439, Blast_Score=70, Evalue=4e-12, Organism=Homo sapiens, GI4505601, Length=164, Percent_Identity=27.4390243902439, Blast_Score=70, Evalue=4e-12, Organism=Homo sapiens, GI14589900, Length=231, Percent_Identity=23.3766233766234, Blast_Score=70, Evalue=5e-12, Organism=Homo sapiens, GI7661974, Length=236, Percent_Identity=27.1186440677966, Blast_Score=69, Evalue=1e-11, Organism=Homo sapiens, GI38327572, Length=196, Percent_Identity=30.1020408163265, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI38327570, Length=196, Percent_Identity=30.1020408163265, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI38327568, Length=196, Percent_Identity=30.1020408163265, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI38327566, Length=196, Percent_Identity=30.1020408163265, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI38327564, Length=196, Percent_Identity=30.1020408163265, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI38327562, Length=196, Percent_Identity=30.1020408163265, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI66932999, Length=172, Percent_Identity=30.8139534883721, Blast_Score=66, Evalue=6e-11, Organism=Homo sapiens, GI21618349, Length=266, Percent_Identity=23.3082706766917, Blast_Score=65, Evalue=1e-10, Organism=Caenorhabditis elegans, GI17505246, Length=189, Percent_Identity=30.1587301587302, Blast_Score=76, Evalue=4e-14, Organism=Caenorhabditis elegans, GI193208795, Length=171, Percent_Identity=32.1637426900585, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI133901722, Length=258, Percent_Identity=25.1937984496124, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI193208793, Length=171, Percent_Identity=32.1637426900585, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI133901724, Length=258, Percent_Identity=25.1937984496124, Blast_Score=74, Evalue=2e-13, Organism=Caenorhabditis elegans, GI193205134, Length=258, Percent_Identity=25.1937984496124, Blast_Score=74, Evalue=2e-13, Organism=Caenorhabditis elegans, GI71985427, Length=216, Percent_Identity=25.462962962963, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17569713, Length=216, Percent_Identity=27.3148148148148, Blast_Score=71, Evalue=8e-13, Organism=Caenorhabditis elegans, GI72001366, Length=169, Percent_Identity=30.7692307692308, Blast_Score=71, Evalue=9e-13, Organism=Caenorhabditis elegans, GI71985415, Length=216, Percent_Identity=25.462962962963, Blast_Score=71, Evalue=1e-12, Organism=Caenorhabditis elegans, GI71985422, Length=216, Percent_Identity=25.462962962963, Blast_Score=71, Evalue=1e-12, Organism=Caenorhabditis elegans, GI212642059, Length=216, Percent_Identity=25.462962962963, Blast_Score=71, Evalue=1e-12, Organism=Caenorhabditis elegans, GI71990759, Length=165, Percent_Identity=28.4848484848485, Blast_Score=70, Evalue=2e-12, Organism=Caenorhabditis elegans, GI25151367, Length=165, Percent_Identity=28.4848484848485, Blast_Score=70, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17508425, Length=205, Percent_Identity=29.7560975609756, Blast_Score=70, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17567859, Length=165, Percent_Identity=28.4848484848485, Blast_Score=70, Evalue=2e-12, Organism=Caenorhabditis elegans, GI193204599, Length=177, Percent_Identity=32.7683615819209, Blast_Score=68, Evalue=1e-11, Organism=Caenorhabditis elegans, GI133951912, Length=189, Percent_Identity=29.6296296296296, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17557200, Length=165, Percent_Identity=26.6666666666667, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI133951926, Length=189, Percent_Identity=29.6296296296296, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI71982774, Length=164, Percent_Identity=27.4390243902439, Blast_Score=67, Evalue=2e-11, Organism=Caenorhabditis elegans, GI71982766, Length=164, Percent_Identity=27.4390243902439, Blast_Score=67, Evalue=2e-11, Organism=Caenorhabditis elegans, GI71982783, Length=164, Percent_Identity=27.4390243902439, Blast_Score=67, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6325117, Length=178, Percent_Identity=28.0898876404494, Blast_Score=80, Evalue=4e-16, Organism=Saccharomyces cerevisiae, GI6324805, Length=241, Percent_Identity=24.4813278008299, Blast_Score=79, Evalue=8e-16, Organism=Saccharomyces cerevisiae, GI6320102, Length=248, Percent_Identity=28.2258064516129, Blast_Score=68, Evalue=2e-12, Organism=Saccharomyces cerevisiae, GI6321780, Length=243, Percent_Identity=24.6913580246914, Blast_Score=68, Evalue=2e-12, Organism=Saccharomyces cerevisiae, GI6323394, Length=171, Percent_Identity=26.9005847953216, Blast_Score=68, Evalue=2e-12, Organism=Saccharomyces cerevisiae, GI6321259, Length=224, Percent_Identity=26.7857142857143, Blast_Score=68, Evalue=2e-12, Organism=Saccharomyces cerevisiae, GI6325047, Length=177, Percent_Identity=27.1186440677966, Blast_Score=67, Evalue=4e-12, Organism=Saccharomyces cerevisiae, GI6323125, Length=216, Percent_Identity=24.537037037037, Blast_Score=66, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6319917, Length=182, Percent_Identity=26.3736263736264, Blast_Score=65, Evalue=2e-11, Organism=Drosophila melanogaster, GI18858209, Length=165, Percent_Identity=31.5151515151515, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI17647993, Length=195, Percent_Identity=29.7435897435897, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI281361563, Length=260, Percent_Identity=25.3846153846154, Blast_Score=72, Evalue=8e-13, Organism=Drosophila melanogaster, GI21356423, Length=260, Percent_Identity=25.3846153846154, Blast_Score=72, Evalue=8e-13, Organism=Drosophila melanogaster, GI17137200, Length=247, Percent_Identity=25.5060728744939, Blast_Score=71, Evalue=2e-12, Organism=Drosophila melanogaster, GI24642565, Length=260, Percent_Identity=27.3076923076923, Blast_Score=70, Evalue=3e-12, Organism=Drosophila melanogaster, GI221378052, Length=165, Percent_Identity=28.4848484848485, Blast_Score=69, Evalue=6e-12, Organism=Drosophila melanogaster, GI17864254, Length=165, Percent_Identity=28.4848484848485, Blast_Score=69, Evalue=6e-12, Organism=Drosophila melanogaster, GI24644584, Length=165, Percent_Identity=28.4848484848485, Blast_Score=69, Evalue=6e-12, Organism=Drosophila melanogaster, GI24644586, Length=165, Percent_Identity=28.4848484848485, Blast_Score=69, Evalue=6e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011009 - InterPro: IPR005543 - InterPro: IPR000719 - InterPro: IPR017441 - InterPro: IPR017442 - InterPro: IPR008271 - InterPro: IPR002290 [H]
Pfam domain/function: PF03793 PASTA; PF00069 Pkinase [H]
EC number: =2.7.11.1 [H]
Molecular weight: Translated: 42763; Mature: 42632
Theoretical pI: Translated: 4.98; Mature: 4.98
Prosite motif: PS50011 PROTEIN_KINASE_DOM
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 2.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTKRSEDEVSTEEFPPRPPTPPSPSSPHFLFVVDDVRYEAVGELEVRSNGEKLLKAERRV CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHCCEEECCCCHHHHHHHHHH ADGVLAGPCLVRRIATPSTYMMRTRLIEEVQLAFRLNHPNIAQVFHMQVDEEADAPFAVM HCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHEEECCCCCCCCHHHH EYVGGPSLETLVTAALVRGKPLSEGFALYVGAEVADALHYAHTLTSEEGVPLGIVHRDVS HHCCCCCHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHHHHHCCCCCCEEEEEECCCC PRRLALGPHGEVKVLDFGAAYSLMVGREESPENLLRGDVAYASPEYLRKEGLTPRSDVFS CCEEEECCCCCEEEEECCCEEEEEECCCCCHHHHHHCCCCCCCHHHHHHCCCCCHHHHHH LGVLLVEVLTSKHLFEVHDVPVVASKETRFVTESPPTLPLQQMQALMETFTPDVVEKAVA HHHHHHHHHHHCHHEEECCCCEEECCCCEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHH HLSEDLKAVLHTALRLNPEERFATAADMRDALRGVAHAQLRAPYGRAEAAKEAALVVSEG HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHEEEEECC GVLRDQVEFGEAGLYPDGLEKHELGLPKKE CCEEHHHHHCCCCCCCCCCCHHHCCCCCCC >Mature Secondary Structure TKRSEDEVSTEEFPPRPPTPPSPSSPHFLFVVDDVRYEAVGELEVRSNGEKLLKAERRV CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHCCEEECCCCHHHHHHHHHH ADGVLAGPCLVRRIATPSTYMMRTRLIEEVQLAFRLNHPNIAQVFHMQVDEEADAPFAVM HCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHEEECCCCCCCCHHHH EYVGGPSLETLVTAALVRGKPLSEGFALYVGAEVADALHYAHTLTSEEGVPLGIVHRDVS HHCCCCCHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHHHHHCCCCCCEEEEEECCCC PRRLALGPHGEVKVLDFGAAYSLMVGREESPENLLRGDVAYASPEYLRKEGLTPRSDVFS CCEEEECCCCCEEEEECCCEEEEEECCCCCHHHHHHCCCCCCCHHHHHHCCCCCHHHHHH LGVLLVEVLTSKHLFEVHDVPVVASKETRFVTESPPTLPLQQMQALMETFTPDVVEKAVA HHHHHHHHHHHCHHEEECCCCEEECCCCEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHH HLSEDLKAVLHTALRLNPEERFATAADMRDALRGVAHAQLRAPYGRAEAAKEAALVVSEG HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHEEEEECC GVLRDQVEFGEAGLYPDGLEKHELGLPKKE CCEEHHHHHCCCCCCCCCCCHHHCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8969512; 11234002 [H]