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The map label for this gene is gpmI

Identifier: 108757281

GI number: 108757281

Start: 1448731

End: 1450272

Strand: Reverse

Name: gpmI

Synonym: MXAN_1236

Alternate gene names: 108757281

Gene position: 1450272-1448731 (Counterclockwise)

Preceding gene: 108761114

Following gene: 108759781

Centisome position: 15.87

GC content: 68.81

Gene sequence:

>1542_bases
ATGACGCCCGCGCACAAGGTCCTGCTCTGCATCCTGGATGGTTGGGGTATTCGCCAGGAGCGTGACAACAACGCCATCGT
CCTGGCCGGCACGCCGCACCTCGACAAGCTGGCGAGCCCCTACCCCTTCACCGAGCTGCAGACGGCGGGTCTGGCCGTGG
GCCTGCCCGAGGGGCAGATGGGCAACTCCGAGGTGGGCCACACCAACATCGGCGCCGGGCGAATCGTCTACCAGGACCTG
GTGCGCATCAATCGCGCCGCGGAGTCCGGAGAGCTGGCGCAGAACCCCGTGCTTCGCGCGGCCCTCGACGGAGTGAAGGC
GGACGGCAAGGCCCTGCACCTGCTGGGGCTGGTGTCGCCCGGCGGCGTCCATTCCTCCATGGACCACCTGTTCGCGCTGC
TCAAGGCCGCGAAGGAACGCAACGTGGCCCATGTCTACGTGCACGCCTTCCTGGACGGGCGTGACACGCCGCCGCAGAGC
GCGCTGGGCTACGTGGAGGAGCTGGAGCGCTTCCTCCATGAGACGCACACCGGCCGCATCGCCACCGTGACCGGGCGCTT
CTACGCCATGGACCGCGACAAGCGCTGGGACCGGGTGCACCAGGCCTACGAGGCGCTGGTGTTCGGCCGCGGGCCCAAGG
CGCCGGACGCGCTGAGCGCCATCCGTGCGTCCTACGCGGAGAAGGTCACCGACGAGTTCGTGAAGCCCACGGTGCTGGCC
GCCGGTGACGGCACGCCGGTGGGCCGCATCCAGGATGGCGATGCGGTGATCTTCTTCAACTTCCGCGCAGACCGGGCGCG
GGAGCTGACGCAGGCCCTGGCGTTCCCGGAGTTCAAGGAGTTCGACCGGGGCGGGCTGCGGCTGGGGCGCTACGTGTGCA
TGACCCAGTACGACGAGACCTTCAAGCTGCCGGCGCTCTTCGAGCCGGACCAGCCGCAGGACATCTTCCCGGAGCTGCTG
TCACGCCAGGGGCTGCGCCAGTTCCGCACGGCGGAGACGGAGAAGTACGCGCACGTCACGTTCTTCTTCAACGGCGGCCG
CGAGGTCGTCTACGCGGGCGAGGACCGGCACCTGGTGCCCAGCCCGCGCGACGTGAAGACGTACGACTTGAAGCCGGAGA
TGTCCGCCTACGAAGTCACGGCCGAGTTGGTGAAGCGGCTCGACTCCGGGAAGTACGACTTCGCGCTGGTGAACTTCGCC
AACCCGGACATGGTGGGCCACAGCGGGCGGCTGGACGCGGCGATGAAGGCGGTGAAGGCGGTGGATGAATGCCTGGGCGC
GCTGGGCAAGGCGTGCGAGCGCAACGGCTGGGTGCTGGCCATCTCCGCCGACCACGGCAACTGCGAGCAGATGGTGGACC
TGGAGACGGGCGAGCCCCACACCGCGCACACGCTCAACCCGGTGCCCTTCCACCTCATCCACCCGGACTTCCGCGGGCAG
AAGCTGCGCCCGGGCATCCTCGCGGACATCGCGCCCACCCTGTGCAAGGTGATGGGATTGCCGCAGTCCAAGGAGATGAA
CCGCCAGGGCCTGCTGCCGTGA

Upstream 100 bases:

>100_bases
GGCTGGGTTTCGTACCCCAGGGGACCTTCCGCGAGTATCAATAGACGCGCTCGCTTTTTGTCCTCTCCCGTCTGGCGCCT
GCATGGTTAGGGTTCGGAGC

Downstream 100 bases:

>100_bases
TGCGCGTGGGGCACGGCCCGTGCTGAAAGCCCTGCTGGACGTGCTCTATCCCCCTTCGTGCCTCGCGTGCACGAAGGTGC
TGCCGGGCCCAGAGGGCTTC

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-independent PGAM; Phosphoglyceromutase; iPGM

Number of amino acids: Translated: 513; Mature: 512

Protein sequence:

>513_residues
MTPAHKVLLCILDGWGIRQERDNNAIVLAGTPHLDKLASPYPFTELQTAGLAVGLPEGQMGNSEVGHTNIGAGRIVYQDL
VRINRAAESGELAQNPVLRAALDGVKADGKALHLLGLVSPGGVHSSMDHLFALLKAAKERNVAHVYVHAFLDGRDTPPQS
ALGYVEELERFLHETHTGRIATVTGRFYAMDRDKRWDRVHQAYEALVFGRGPKAPDALSAIRASYAEKVTDEFVKPTVLA
AGDGTPVGRIQDGDAVIFFNFRADRARELTQALAFPEFKEFDRGGLRLGRYVCMTQYDETFKLPALFEPDQPQDIFPELL
SRQGLRQFRTAETEKYAHVTFFFNGGREVVYAGEDRHLVPSPRDVKTYDLKPEMSAYEVTAELVKRLDSGKYDFALVNFA
NPDMVGHSGRLDAAMKAVKAVDECLGALGKACERNGWVLAISADHGNCEQMVDLETGEPHTAHTLNPVPFHLIHPDFRGQ
KLRPGILADIAPTLCKVMGLPQSKEMNRQGLLP

Sequences:

>Translated_513_residues
MTPAHKVLLCILDGWGIRQERDNNAIVLAGTPHLDKLASPYPFTELQTAGLAVGLPEGQMGNSEVGHTNIGAGRIVYQDL
VRINRAAESGELAQNPVLRAALDGVKADGKALHLLGLVSPGGVHSSMDHLFALLKAAKERNVAHVYVHAFLDGRDTPPQS
ALGYVEELERFLHETHTGRIATVTGRFYAMDRDKRWDRVHQAYEALVFGRGPKAPDALSAIRASYAEKVTDEFVKPTVLA
AGDGTPVGRIQDGDAVIFFNFRADRARELTQALAFPEFKEFDRGGLRLGRYVCMTQYDETFKLPALFEPDQPQDIFPELL
SRQGLRQFRTAETEKYAHVTFFFNGGREVVYAGEDRHLVPSPRDVKTYDLKPEMSAYEVTAELVKRLDSGKYDFALVNFA
NPDMVGHSGRLDAAMKAVKAVDECLGALGKACERNGWVLAISADHGNCEQMVDLETGEPHTAHTLNPVPFHLIHPDFRGQ
KLRPGILADIAPTLCKVMGLPQSKEMNRQGLLP
>Mature_512_residues
TPAHKVLLCILDGWGIRQERDNNAIVLAGTPHLDKLASPYPFTELQTAGLAVGLPEGQMGNSEVGHTNIGAGRIVYQDLV
RINRAAESGELAQNPVLRAALDGVKADGKALHLLGLVSPGGVHSSMDHLFALLKAAKERNVAHVYVHAFLDGRDTPPQSA
LGYVEELERFLHETHTGRIATVTGRFYAMDRDKRWDRVHQAYEALVFGRGPKAPDALSAIRASYAEKVTDEFVKPTVLAA
GDGTPVGRIQDGDAVIFFNFRADRARELTQALAFPEFKEFDRGGLRLGRYVCMTQYDETFKLPALFEPDQPQDIFPELLS
RQGLRQFRTAETEKYAHVTFFFNGGREVVYAGEDRHLVPSPRDVKTYDLKPEMSAYEVTAELVKRLDSGKYDFALVNFAN
PDMVGHSGRLDAAMKAVKAVDECLGALGKACERNGWVLAISADHGNCEQMVDLETGEPHTAHTLNPVPFHLIHPDFRGQK
LRPGILADIAPTLCKVMGLPQSKEMNRQGLLP

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0696

COG function: function code G; Phosphoglyceromutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BPG-independent phosphoglycerate mutase family

Homologues:

Organism=Escherichia coli, GI1790041, Length=507, Percent_Identity=48.1262327416174, Blast_Score=473, Evalue=1e-134,
Organism=Caenorhabditis elegans, GI32564249, Length=513, Percent_Identity=46.9785575048733, Blast_Score=455, Evalue=1e-128,
Organism=Caenorhabditis elegans, GI17507741, Length=513, Percent_Identity=46.9785575048733, Blast_Score=454, Evalue=1e-128,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPMI_MYXXD (Q1DCX8)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_629495.1
- ProteinModelPortal:   Q1DCX8
- SMR:   Q1DCX8
- STRING:   Q1DCX8
- GeneID:   4103242
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_1236
- TIGR:   MXAN_1236
- eggNOG:   COG0696
- HOGENOM:   HBG613255
- OMA:   DNKTDEF
- PhylomeDB:   Q1DCX8
- ProtClustDB:   PRK05434
- BioCyc:   MXAN246197:MXAN_1236-MONOMER
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_01038
- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR011258
- InterPro:   IPR006124
- InterPro:   IPR005995
- Gene3D:   G3DSA:3.40.720.10
- Gene3D:   G3DSA:3.40.1450.10
- PIRSF:   PIRSF001492
- TIGRFAMs:   TIGR01307

Pfam domain/function: PF06415 iPGM_N; PF01676 Metalloenzyme; SSF53649 Alkaline_phosphatase_core; SSF64158 BPG-indep_PGM_N

EC number: =5.4.2.1

Molecular weight: Translated: 56554; Mature: 56423

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: ACT_SITE 63-63

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPAHKVLLCILDGWGIRQERDNNAIVLAGTPHLDKLASPYPFTELQTAGLAVGLPEGQM
CCCHHEEEEEEECCCCCCEECCCCEEEEECCCCHHHHCCCCCCHHHHHCCEEEECCCCCC
GNSEVGHTNIGAGRIVYQDLVRINRAAESGELAQNPVLRAALDGVKADGKALHLLGLVSP
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHCCCCCCCEEEEEEECCC
GGVHSSMDHLFALLKAAKERNVAHVYVHAFLDGRDTPPQSALGYVEELERFLHETHTGRI
CCCHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEE
ATVTGRFYAMDRDKRWDRVHQAYEALVFGRGPKAPDALSAIRASYAEKVTDEFVKPTVLA
EEEEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEE
AGDGTPVGRIQDGDAVIFFNFRADRARELTQALAFPEFKEFDRGGLRLGRYVCMTQYDET
CCCCCCCCEEECCCEEEEEECCCHHHHHHHHHHCCCCHHHHCCCCHHHHHEEEEECCCCC
FKLPALFEPDQPQDIFPELLSRQGLRQFRTAETEKYAHVTFFFNGGREVVYAGEDRHLVP
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCEEEEECCCCCCCC
SPRDVKTYDLKPEMSAYEVTAELVKRLDSGKYDFALVNFANPDMVGHSGRLDAAMKAVKA
CCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHH
VDECLGALGKACERNGWVLAISADHGNCEQMVDLETGEPHTAHTLNPVPFHLIHPDFRGQ
HHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEECCCCCCCCCCCCCCCEEEECCCCCCC
KLRPGILADIAPTLCKVMGLPQSKEMNRQGLLP
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TPAHKVLLCILDGWGIRQERDNNAIVLAGTPHLDKLASPYPFTELQTAGLAVGLPEGQM
CCHHEEEEEEECCCCCCEECCCCEEEEECCCCHHHHCCCCCCHHHHHCCEEEECCCCCC
GNSEVGHTNIGAGRIVYQDLVRINRAAESGELAQNPVLRAALDGVKADGKALHLLGLVSP
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHCCCCCCCEEEEEEECCC
GGVHSSMDHLFALLKAAKERNVAHVYVHAFLDGRDTPPQSALGYVEELERFLHETHTGRI
CCCHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEE
ATVTGRFYAMDRDKRWDRVHQAYEALVFGRGPKAPDALSAIRASYAEKVTDEFVKPTVLA
EEEEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEE
AGDGTPVGRIQDGDAVIFFNFRADRARELTQALAFPEFKEFDRGGLRLGRYVCMTQYDET
CCCCCCCCEEECCCEEEEEECCCHHHHHHHHHHCCCCHHHHCCCCHHHHHEEEEECCCCC
FKLPALFEPDQPQDIFPELLSRQGLRQFRTAETEKYAHVTFFFNGGREVVYAGEDRHLVP
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCEEEEECCCCCCCC
SPRDVKTYDLKPEMSAYEVTAELVKRLDSGKYDFALVNFANPDMVGHSGRLDAAMKAVKA
CCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHH
VDECLGALGKACERNGWVLAISADHGNCEQMVDLETGEPHTAHTLNPVPFHLIHPDFRGQ
HHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEECCCCCCCCCCCCCCCEEEECCCCCCC
KLRPGILADIAPTLCKVMGLPQSKEMNRQGLLP
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA