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The map label for this gene is betB [H]

Identifier: 108757171

GI number: 108757171

Start: 3308648

End: 3310192

Strand: Direct

Name: betB [H]

Synonym: MXAN_2841

Alternate gene names: 108757171

Gene position: 3308648-3310192 (Clockwise)

Preceding gene: 108761323

Following gene: 108760342

Centisome position: 36.2

GC content: 68.41

Gene sequence:

>1545_bases
ATGGCGAGTGTGGTGCCTGCTTACGCGGAGTGGTCCAATCTGGAGCGCCGAATCCGGGCGCTCGTTCCCGAGGCGTTCGA
CCCGACGGGCCGAGTGCTCAACCTCATCGCGGGTGAATGGGGGCATCCCGGAAAGGGGAAGCCCTACCTGTCCCCGGTTG
ACGGCACCGTCCTGGGCCGCCTGCCCATGATTGATGCGAACACCGCGCGCGTCGCCGCGAGCGCCGCCGCCGCGGAGGCA
CGGACCTGGGCCCACCAGGACCTCGATGCGCGCAAGGAGCGCGTCACCCAGTGCCTGTCCCTGCTGCGTGAGCAGCGCGA
GCTGTTGGCTCTCATCCTGGCCTGGGAGATTGGCAAGCCGGTGCCACAGGCTCGCGTCAGCGTGGACCGCTGTATCTCTG
GCGTGGAGTGGTACGTCTCCCAAATCGAGCCCATGGTGGAGGGCCGCCGTCCGCTGGGGCTCATCTCCAACATCGCTTCA
TGGAACTACCCACTGTCGGTGCTGGTCCACGCGGTGCTGGTCCAGGTGCTCGCGGGCAACAGCGCCATCGCCAAGACGCC
CACGGATGGTGGTCTCTACTCGCTGACGCTCTGCATGGGGCTCGCGCGCCGCTGCGGGCTGCCTGTGTCGCTCATCAGTG
GCTCGGGCGGACAGCTCAGCGACGCGCTGGTGCGCAATCCGGAGATCGCCTGCCTGTCCTTCGTGGGCGGCAAGGCGAAC
GGGCGGGACATCGCCGCCAGCCTCTATGACCGCAACAAGCGCTACATGCTGGAGATGGAAGGGGTGAATGCCTACGGCAT
CTGGCACTTCAGCGACTGGGACGGGCTGGCGAAGCAGCTCAAGAAGGGCTTCGAGTACGGCAAGCAGCGCTGCACCGCGT
ACCCGCGCTTCGTCGTGGAGCGGAGCCTGATGCCGCGCTTCCTGGAGACGTACCTGCCCGTCGTCTCCGCCCTGAAGGTG
GGGCACCCGCTGCTGGCGGAGTCACCGGATGGCGAGCCTCCCGCGCTCGACTTCGGCCCGCTCATCAACAGCCAGAAGGT
CGAGGAGCTTCACGGCCATATGAGTGAGGCAGAGGGCCGCGGCGCCGTGCCCCTCTTCGCCGGGCGGCTGGACGCGGAGC
GCTTCCTGCCGGACCAGGACGTCTCCGCGTACCTGGCCCCGCACGCGCTGCTGCACGTGCCGCGCAACTGCAAGCTCTAC
CACGGCGAGCCCTTCGGCCCCGTGGACACGCTGGTCGTCGTGGACAGCGAGGAGGAGCTCATCGCGGAGATGAACGTGTC
CAACGGCTCGCTGGTCGCCTCCATCGCCTGCGACGAGCCCGACACGTGCAAGCGCGTCTCCACCGAGCTGCGGGCCTTCA
AGGTCGGCCACAACGGGCCGCGCTCGCGCGGAGACCGGGACGAGGTCTTCGGCGGCATCGGTGGTTCGTGGAAGGGGTGC
TTCGTGGGCGGCAAGTACCTGGTCCAGGCCGTCACCGAGGGCGAACCCGGCGAGCGGCTGCACGGCAACTTCCACGACTA
CACGCAGCTCCCCGACACGCGCTGA

Upstream 100 bases:

>100_bases
GGCGGCGGTTGCCGCGCGCCTCACTTGCCATCACCTTGACGCAATGTGCCGATGCCGGGTGGAGTGTCGGCCTGGTCTCC
TTCCGGGGGAGGGCGTGTTC

Downstream 100 bases:

>100_bases
AGCGGGCTCATCGTCTGCTCGGGCGTCTGGCGCCGCGCACCTCGGCCGCGAACAGTTCCGCGGCGGGCGTGCGCGGCGCG
CCTTTTCGCCACAGGAGCGC

Product: aldehyde dehydrogenase family protein

Products: NA

Alternate protein names: BADH [H]

Number of amino acids: Translated: 514; Mature: 513

Protein sequence:

>514_residues
MASVVPAYAEWSNLERRIRALVPEAFDPTGRVLNLIAGEWGHPGKGKPYLSPVDGTVLGRLPMIDANTARVAASAAAAEA
RTWAHQDLDARKERVTQCLSLLREQRELLALILAWEIGKPVPQARVSVDRCISGVEWYVSQIEPMVEGRRPLGLISNIAS
WNYPLSVLVHAVLVQVLAGNSAIAKTPTDGGLYSLTLCMGLARRCGLPVSLISGSGGQLSDALVRNPEIACLSFVGGKAN
GRDIAASLYDRNKRYMLEMEGVNAYGIWHFSDWDGLAKQLKKGFEYGKQRCTAYPRFVVERSLMPRFLETYLPVVSALKV
GHPLLAESPDGEPPALDFGPLINSQKVEELHGHMSEAEGRGAVPLFAGRLDAERFLPDQDVSAYLAPHALLHVPRNCKLY
HGEPFGPVDTLVVVDSEEELIAEMNVSNGSLVASIACDEPDTCKRVSTELRAFKVGHNGPRSRGDRDEVFGGIGGSWKGC
FVGGKYLVQAVTEGEPGERLHGNFHDYTQLPDTR

Sequences:

>Translated_514_residues
MASVVPAYAEWSNLERRIRALVPEAFDPTGRVLNLIAGEWGHPGKGKPYLSPVDGTVLGRLPMIDANTARVAASAAAAEA
RTWAHQDLDARKERVTQCLSLLREQRELLALILAWEIGKPVPQARVSVDRCISGVEWYVSQIEPMVEGRRPLGLISNIAS
WNYPLSVLVHAVLVQVLAGNSAIAKTPTDGGLYSLTLCMGLARRCGLPVSLISGSGGQLSDALVRNPEIACLSFVGGKAN
GRDIAASLYDRNKRYMLEMEGVNAYGIWHFSDWDGLAKQLKKGFEYGKQRCTAYPRFVVERSLMPRFLETYLPVVSALKV
GHPLLAESPDGEPPALDFGPLINSQKVEELHGHMSEAEGRGAVPLFAGRLDAERFLPDQDVSAYLAPHALLHVPRNCKLY
HGEPFGPVDTLVVVDSEEELIAEMNVSNGSLVASIACDEPDTCKRVSTELRAFKVGHNGPRSRGDRDEVFGGIGGSWKGC
FVGGKYLVQAVTEGEPGERLHGNFHDYTQLPDTR
>Mature_513_residues
ASVVPAYAEWSNLERRIRALVPEAFDPTGRVLNLIAGEWGHPGKGKPYLSPVDGTVLGRLPMIDANTARVAASAAAAEAR
TWAHQDLDARKERVTQCLSLLREQRELLALILAWEIGKPVPQARVSVDRCISGVEWYVSQIEPMVEGRRPLGLISNIASW
NYPLSVLVHAVLVQVLAGNSAIAKTPTDGGLYSLTLCMGLARRCGLPVSLISGSGGQLSDALVRNPEIACLSFVGGKANG
RDIAASLYDRNKRYMLEMEGVNAYGIWHFSDWDGLAKQLKKGFEYGKQRCTAYPRFVVERSLMPRFLETYLPVVSALKVG
HPLLAESPDGEPPALDFGPLINSQKVEELHGHMSEAEGRGAVPLFAGRLDAERFLPDQDVSAYLAPHALLHVPRNCKLYH
GEPFGPVDTLVVVDSEEELIAEMNVSNGSLVASIACDEPDTCKRVSTELRAFKVGHNGPRSRGDRDEVFGGIGGSWKGCF
VGGKYLVQAVTEGEPGERLHGNFHDYTQLPDTR

Specific function: 4-aminobutyrate (GABA) degradation. [C]

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI12007648, Length=445, Percent_Identity=24.7191011235955, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI115387104, Length=419, Percent_Identity=23.3890214797136, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI4507229, Length=450, Percent_Identity=23.1111111111111, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI25777730, Length=449, Percent_Identity=23.8307349665924, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI153266822, Length=414, Percent_Identity=22.7053140096618, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI25777721, Length=462, Percent_Identity=22.5108225108225, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI25777732, Length=483, Percent_Identity=23.3954451345756, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI188035924, Length=421, Percent_Identity=23.0403800475059, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI310128103, Length=421, Percent_Identity=23.0403800475059, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI25777724, Length=449, Percent_Identity=23.3853006681514, Blast_Score=93, Evalue=8e-19,
Organism=Homo sapiens, GI310128093, Length=421, Percent_Identity=22.8028503562945, Blast_Score=93, Evalue=8e-19,
Organism=Homo sapiens, GI238814322, Length=482, Percent_Identity=24.2738589211618, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI25777728, Length=386, Percent_Identity=23.3160621761658, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI310128091, Length=300, Percent_Identity=24.3333333333333, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI21361176, Length=449, Percent_Identity=22.4944320712695, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI301500698, Length=449, Percent_Identity=21.826280623608, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI11095441, Length=430, Percent_Identity=22.093023255814, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI21614513, Length=481, Percent_Identity=23.9085239085239, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI310128089, Length=288, Percent_Identity=24.6527777777778, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI25952152, Length=241, Percent_Identity=25.3112033195021, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1789015, Length=482, Percent_Identity=26.1410788381743, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1787558, Length=472, Percent_Identity=26.4830508474576, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI87081926, Length=452, Percent_Identity=25.6637168141593, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI87082295, Length=452, Percent_Identity=23.2300884955752, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787715, Length=437, Percent_Identity=24.7139588100687, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1786504, Length=440, Percent_Identity=24.7727272727273, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI87081896, Length=452, Percent_Identity=25.4424778761062, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1787684, Length=453, Percent_Identity=23.6203090507726, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1788042, Length=461, Percent_Identity=26.0303687635575, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1787250, Length=423, Percent_Identity=22.4586288416076, Blast_Score=76, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17551164, Length=502, Percent_Identity=23.1075697211155, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17534119, Length=447, Percent_Identity=22.8187919463087, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI25143876, Length=424, Percent_Identity=24.7641509433962, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI25143874, Length=421, Percent_Identity=24.7030878859857, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71995606, Length=456, Percent_Identity=24.5614035087719, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71986308, Length=437, Percent_Identity=25.1716247139588, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71995613, Length=412, Percent_Identity=24.5145631067961, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562198, Length=431, Percent_Identity=21.3457076566125, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI25144435, Length=472, Percent_Identity=22.6694915254237, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI133930964, Length=489, Percent_Identity=23.1083844580777, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI32564736, Length=426, Percent_Identity=22.3004694835681, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI115534176, Length=426, Percent_Identity=22.3004694835681, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319478, Length=430, Percent_Identity=23.4883720930233, Blast_Score=110, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6324950, Length=400, Percent_Identity=22.5, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6320917, Length=493, Percent_Identity=22.7180527383367, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6325196, Length=459, Percent_Identity=23.9651416122004, Blast_Score=94, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6323822, Length=426, Percent_Identity=23.0046948356808, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6323821, Length=359, Percent_Identity=23.9554317548747, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6321828, Length=471, Percent_Identity=21.4437367303609, Blast_Score=90, Evalue=7e-19,
Organism=Drosophila melanogaster, GI281362580, Length=448, Percent_Identity=24.5535714285714, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI62472918, Length=448, Percent_Identity=24.5535714285714, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI62472926, Length=448, Percent_Identity=24.5535714285714, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI62472936, Length=448, Percent_Identity=24.5535714285714, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI21356737, Length=448, Percent_Identity=24.5535714285714, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24666674, Length=421, Percent_Identity=23.5154394299287, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24650465, Length=411, Percent_Identity=21.8978102189781, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI20129399, Length=442, Percent_Identity=21.7194570135747, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24638876, Length=449, Percent_Identity=22.9398663697105, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24638878, Length=449, Percent_Identity=22.9398663697105, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR011264 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.8 [H]

Molecular weight: Translated: 56025; Mature: 55893

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASVVPAYAEWSNLERRIRALVPEAFDPTGRVLNLIAGEWGHPGKGKPYLSPVDGTVLGR
CCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECC
LPMIDANTARVAASAAAAEARTWAHQDLDARKERVTQCLSLLREQRELLALILAWEIGKP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VPQARVSVDRCISGVEWYVSQIEPMVEGRRPLGLISNIASWNYPLSVLVHAVLVQVLAGN
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
SAIAKTPTDGGLYSLTLCMGLARRCGLPVSLISGSGGQLSDALVRNPEIACLSFVGGKAN
CCEECCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHCCCCEEEEEEECCCCC
GRDIAASLYDRNKRYMLEMEGVNAYGIWHFSDWDGLAKQLKKGFEYGKQRCTAYPRFVVE
CHHHHHHHHHCCCEEEEEECCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSLMPRFLETYLPVVSALKVGHPLLAESPDGEPPALDFGPLINSQKVEELHGHMSEAEGR
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
GAVPLFAGRLDAERFLPDQDVSAYLAPHALLHVPRNCKLYHGEPFGPVDTLVVVDSEEEL
CCCEEEECCCCHHHCCCCCCCHHHHCCHHHHCCCCCCEEECCCCCCCCCEEEEECCHHHH
IAEMNVSNGSLVASIACDEPDTCKRVSTELRAFKVGHNGPRSRGDRDEVFGGIGGSWKGC
HHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHEECCCCCCCCCCCHHHHHCCCCCCCCEE
FVGGKYLVQAVTEGEPGERLHGNFHDYTQLPDTR
EECHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
ASVVPAYAEWSNLERRIRALVPEAFDPTGRVLNLIAGEWGHPGKGKPYLSPVDGTVLGR
CCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECC
LPMIDANTARVAASAAAAEARTWAHQDLDARKERVTQCLSLLREQRELLALILAWEIGKP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VPQARVSVDRCISGVEWYVSQIEPMVEGRRPLGLISNIASWNYPLSVLVHAVLVQVLAGN
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
SAIAKTPTDGGLYSLTLCMGLARRCGLPVSLISGSGGQLSDALVRNPEIACLSFVGGKAN
CCEECCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHCCCCEEEEEEECCCCC
GRDIAASLYDRNKRYMLEMEGVNAYGIWHFSDWDGLAKQLKKGFEYGKQRCTAYPRFVVE
CHHHHHHHHHCCCEEEEEECCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSLMPRFLETYLPVVSALKVGHPLLAESPDGEPPALDFGPLINSQKVEELHGHMSEAEGR
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
GAVPLFAGRLDAERFLPDQDVSAYLAPHALLHVPRNCKLYHGEPFGPVDTLVVVDSEEEL
CCCEEEECCCCHHHCCCCCCCHHHHCCHHHHCCCCCCEEECCCCCCCCCEEEEECCHHHH
IAEMNVSNGSLVASIACDEPDTCKRVSTELRAFKVGHNGPRSRGDRDEVFGGIGGSWKGC
HHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHEECCCCCCCCCCCHHHHHCCCCCCCCEE
FVGGKYLVQAVTEGEPGERLHGNFHDYTQLPDTR
EECHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA