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The map label for this gene is yngJ [H]

Identifier: 108757129

GI number: 108757129

Start: 3577173

End: 3578324

Strand: Direct

Name: yngJ [H]

Synonym: MXAN_3048

Alternate gene names: 108757129

Gene position: 3577173-3578324 (Clockwise)

Preceding gene: 108762173

Following gene: 108758330

Centisome position: 39.14

GC content: 68.14

Gene sequence:

>1152_bases
ATGCTTCACGGCCAAGGGCTGTACCTGGAAGAGCATGACGCGTTTCGTCGCACCGTACGTGCGGTGGTGGAGAAGGAGAT
TCTCCCCTTCGTGAAGGAGTGGGAGGCCCGGGAGGCGTTCCCCCGGGAGCTCTTCACCCGCTTTGGCGAGCTGGGCTTCC
TCGGCCTGAAGTATCCGGTGGAGTACGGGGGCTCGGCGGCGGGGGAGCTGTATGAGGCGGTGTTGCTGGAGGAGCTGGGG
CGCTGTGGCTCGGGCGGTGTGTCCGCGGGGCTGGGGGCCCAGTTCACCATCTCCACGGGGCCCATCCATCAGTTCGGCAC
GGACGCGCAGAAGCTCCGCTGGCTGGCCCCCGCCATCCGGGGCGAGAAGATTGGCGCGCTGGGCATCACCGAACCGGACG
CGGGCTCGGACGTGGCGGGGCTGCGCACCACCGCTCGGCGCGAGGGCGACAGCTACGTCCTCAACGGCTCCAAGACGTAC
ATCACCAACGGTGTGCGCGCGGACTTCGTGGTGCTGGCGGTGAAGACGGATCCGTCCGCGGGTCACAAGGGCCTGTCCAT
GGTGGTGGTGGAGAAGGGCACGCCAGGCTTCTCCGTGGGACGCAAGCTGGACAAGCTCGGCTGGCGCGCCTCAGACACCG
CGGAGCTGTTCTTCGAGGACTGCCGCGTGCCCGCGGAGAACCTGCTCGGCGTGGAAGGGCAGGGCTTCGCGCAGATCATG
GGCAACTTCCAGTGGGAGCGCCTGTCGCTCGCGCTGGGGGCGGTGGGGGCCATGGAGGACATGCTGGAGACGGTGCTGGC
GCAGGTGAAGTCACGGCGTGCCTTCGGCCAGTCGCTCCACCAGTTCCAGGTGGTGCGCCACAAGCTGGCGGAGCTCTTCA
CCGCGCGCGAGTCGGCGCGCCAGCTCACCTACCACGCGCTGCGCCTGCACGTGGCCGGTGAGTGGGCGGTGGCGCAGACG
TCCATGGCGAAGAAGGTGGCCACCGAGACGTGCTGCCGCGTGGCGGATGAGTGTCTCCAACTCCATGGCGGCGCGGGCTA
CATGATGGAGTACGACATCCAGCGCCACTGGCGTGACGCACGGCTGGGGCCCATCGGCGGTGGCACCAGCGAGGTGATGA
ACGAAATCATCGCCAAGCAGCTCGGACTGTAG

Upstream 100 bases:

>100_bases
CTGCCTGCTGTGCATGCGTCCCATTACCATGCCGTTACCAGAAGGTTCCACCCCGGGTGCGCGTGCGTACGGGCACCCGA
AAGGACGAGGTGCTCGAAAG

Downstream 100 bases:

>100_bases
GGCGGGAGCGCGGTGCGGCACGGCGCCCCGCCTGTCACGTGGAGGGCAGGCGGGGGGGCGGCGTGGGAAGAGGCCCTTGG
AGCTCTGGGTTACCCGAAGA

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MLHGQGLYLEEHDAFRRTVRAVVEKEILPFVKEWEAREAFPRELFTRFGELGFLGLKYPVEYGGSAAGELYEAVLLEELG
RCGSGGVSAGLGAQFTISTGPIHQFGTDAQKLRWLAPAIRGEKIGALGITEPDAGSDVAGLRTTARREGDSYVLNGSKTY
ITNGVRADFVVLAVKTDPSAGHKGLSMVVVEKGTPGFSVGRKLDKLGWRASDTAELFFEDCRVPAENLLGVEGQGFAQIM
GNFQWERLSLALGAVGAMEDMLETVLAQVKSRRAFGQSLHQFQVVRHKLAELFTARESARQLTYHALRLHVAGEWAVAQT
SMAKKVATETCCRVADECLQLHGGAGYMMEYDIQRHWRDARLGPIGGGTSEVMNEIIAKQLGL

Sequences:

>Translated_383_residues
MLHGQGLYLEEHDAFRRTVRAVVEKEILPFVKEWEAREAFPRELFTRFGELGFLGLKYPVEYGGSAAGELYEAVLLEELG
RCGSGGVSAGLGAQFTISTGPIHQFGTDAQKLRWLAPAIRGEKIGALGITEPDAGSDVAGLRTTARREGDSYVLNGSKTY
ITNGVRADFVVLAVKTDPSAGHKGLSMVVVEKGTPGFSVGRKLDKLGWRASDTAELFFEDCRVPAENLLGVEGQGFAQIM
GNFQWERLSLALGAVGAMEDMLETVLAQVKSRRAFGQSLHQFQVVRHKLAELFTARESARQLTYHALRLHVAGEWAVAQT
SMAKKVATETCCRVADECLQLHGGAGYMMEYDIQRHWRDARLGPIGGGTSEVMNEIIAKQLGL
>Mature_383_residues
MLHGQGLYLEEHDAFRRTVRAVVEKEILPFVKEWEAREAFPRELFTRFGELGFLGLKYPVEYGGSAAGELYEAVLLEELG
RCGSGGVSAGLGAQFTISTGPIHQFGTDAQKLRWLAPAIRGEKIGALGITEPDAGSDVAGLRTTARREGDSYVLNGSKTY
ITNGVRADFVVLAVKTDPSAGHKGLSMVVVEKGTPGFSVGRKLDKLGWRASDTAELFFEDCRVPAENLLGVEGQGFAQIM
GNFQWERLSLALGAVGAMEDMLETVLAQVKSRRAFGQSLHQFQVVRHKLAELFTARESARQLTYHALRLHVAGEWAVAQT
SMAKKVATETCCRVADECLQLHGGAGYMMEYDIQRHWRDARLGPIGGGTSEVMNEIIAKQLGL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=381, Percent_Identity=41.4698162729659, Blast_Score=277, Evalue=1e-74,
Organism=Homo sapiens, GI226958412, Length=374, Percent_Identity=37.9679144385027, Blast_Score=265, Evalue=8e-71,
Organism=Homo sapiens, GI4557233, Length=373, Percent_Identity=38.6058981233244, Blast_Score=263, Evalue=2e-70,
Organism=Homo sapiens, GI226958414, Length=340, Percent_Identity=39.4117647058824, Blast_Score=254, Evalue=9e-68,
Organism=Homo sapiens, GI4501859, Length=374, Percent_Identity=32.8877005347594, Blast_Score=231, Evalue=9e-61,
Organism=Homo sapiens, GI7656849, Length=373, Percent_Identity=34.5844504021448, Blast_Score=228, Evalue=1e-59,
Organism=Homo sapiens, GI187960098, Length=377, Percent_Identity=33.6870026525199, Blast_Score=204, Evalue=8e-53,
Organism=Homo sapiens, GI4557231, Length=377, Percent_Identity=33.6870026525199, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI76496475, Length=340, Percent_Identity=35, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI4557235, Length=340, Percent_Identity=35, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI21361497, Length=366, Percent_Identity=32.2404371584699, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI4503943, Length=347, Percent_Identity=29.971181556196, Blast_Score=138, Evalue=9e-33,
Organism=Homo sapiens, GI7669494, Length=347, Percent_Identity=29.971181556196, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI48976061, Length=284, Percent_Identity=34.1549295774648, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI211971008, Length=284, Percent_Identity=34.1549295774648, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI38505218, Length=318, Percent_Identity=30.8176100628931, Blast_Score=125, Evalue=9e-29,
Organism=Escherichia coli, GI87081958, Length=387, Percent_Identity=29.7157622739018, Blast_Score=157, Evalue=9e-40,
Organism=Escherichia coli, GI1786223, Length=364, Percent_Identity=27.7472527472527, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI87082384, Length=283, Percent_Identity=29.6819787985866, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87081702, Length=333, Percent_Identity=24.024024024024, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17538396, Length=374, Percent_Identity=35.8288770053476, Blast_Score=252, Evalue=3e-67,
Organism=Caenorhabditis elegans, GI17551932, Length=376, Percent_Identity=37.2340425531915, Blast_Score=241, Evalue=5e-64,
Organism=Caenorhabditis elegans, GI17505929, Length=375, Percent_Identity=36, Blast_Score=230, Evalue=8e-61,
Organism=Caenorhabditis elegans, GI17533517, Length=361, Percent_Identity=34.9030470914127, Blast_Score=216, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17508101, Length=370, Percent_Identity=31.8918918918919, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI17570075, Length=370, Percent_Identity=34.3243243243243, Blast_Score=208, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI17506239, Length=374, Percent_Identity=31.5508021390374, Blast_Score=205, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI17534899, Length=358, Percent_Identity=33.2402234636872, Blast_Score=190, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17569725, Length=358, Percent_Identity=31.8435754189944, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI71985184, Length=362, Percent_Identity=32.8729281767956, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI71990804, Length=279, Percent_Identity=33.3333333333333, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17534353, Length=375, Percent_Identity=29.6, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI32563615, Length=232, Percent_Identity=32.7586206896552, Blast_Score=144, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI71985192, Length=286, Percent_Identity=33.5664335664336, Blast_Score=140, Evalue=9e-34,
Organism=Caenorhabditis elegans, GI71982178, Length=274, Percent_Identity=26.6423357664234, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17531909, Length=239, Percent_Identity=28.8702928870293, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17562446, Length=285, Percent_Identity=28.0701754385965, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI21356377, Length=370, Percent_Identity=35.6756756756757, Blast_Score=246, Evalue=2e-65,
Organism=Drosophila melanogaster, GI21355753, Length=376, Percent_Identity=35.6382978723404, Blast_Score=232, Evalue=3e-61,
Organism=Drosophila melanogaster, GI24646207, Length=370, Percent_Identity=34.3243243243243, Blast_Score=219, Evalue=3e-57,
Organism=Drosophila melanogaster, GI24666513, Length=370, Percent_Identity=31.8918918918919, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI24660351, Length=382, Percent_Identity=31.6753926701571, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI281363737, Length=347, Percent_Identity=31.9884726224784, Blast_Score=161, Evalue=6e-40,
Organism=Drosophila melanogaster, GI19920834, Length=360, Percent_Identity=30.8333333333333, Blast_Score=141, Evalue=7e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 41819; Mature: 41819

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00318 HMG_COA_REDUCTASE_2 ; PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHGQGLYLEEHDAFRRTVRAVVEKEILPFVKEWEAREAFPRELFTRFGELGFLGLKYPV
CCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCH
EYGGSAAGELYEAVLLEELGRCGSGGVSAGLGAQFTISTGPIHQFGTDAQKLRWLAPAIR
HCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCHHHCCCHHHHHHHHHHHC
GEKIGALGITEPDAGSDVAGLRTTARREGDSYVLNGSKTYITNGVRADFVVLAVKTDPSA
CCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEECCCCEEEECCCCEEEEEEEEECCCCC
GHKGLSMVVVEKGTPGFSVGRKLDKLGWRASDTAELFFEDCRVPAENLLGVEGQGFAQIM
CCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHCCCCCCCHHHHH
GNFQWERLSLALGAVGAMEDMLETVLAQVKSRRAFGQSLHQFQVVRHKLAELFTARESAR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLTYHALRLHVAGEWAVAQTSMAKKVATETCCRVADECLQLHGGAGYMMEYDIQRHWRDA
HHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHC
RLGPIGGGTSEVMNEIIAKQLGL
CCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLHGQGLYLEEHDAFRRTVRAVVEKEILPFVKEWEAREAFPRELFTRFGELGFLGLKYPV
CCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCH
EYGGSAAGELYEAVLLEELGRCGSGGVSAGLGAQFTISTGPIHQFGTDAQKLRWLAPAIR
HCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCHHHCCCHHHHHHHHHHHC
GEKIGALGITEPDAGSDVAGLRTTARREGDSYVLNGSKTYITNGVRADFVVLAVKTDPSA
CCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEECCCCEEEECCCCEEEEEEEEECCCCC
GHKGLSMVVVEKGTPGFSVGRKLDKLGWRASDTAELFFEDCRVPAENLLGVEGQGFAQIM
CCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHCCCCCCCHHHHH
GNFQWERLSLALGAVGAMEDMLETVLAQVKSRRAFGQSLHQFQVVRHKLAELFTARESAR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLTYHALRLHVAGEWAVAQTSMAKKVATETCCRVADECLQLHGGAGYMMEYDIQRHWRDA
HHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHC
RLGPIGGGTSEVMNEIIAKQLGL
CCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]