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The map label for this gene is ina [H]

Identifier: 108757063

GI number: 108757063

Start: 3689404

End: 3690849

Strand: Direct

Name: ina [H]

Synonym: MXAN_3149

Alternate gene names: 108757063

Gene position: 3689404-3690849 (Clockwise)

Preceding gene: 108760800

Following gene: 108763572

Centisome position: 40.37

GC content: 60.58

Gene sequence:

>1446_bases
GTGTCTGGGTGTCAGGCCTGGCGAAAGGGGTGGGACATGTGCAGCGAGCATTCACCTATCGAGCGGCTTTGCCGCGTTCC
TCCAAGTCCAGAACTCCGGAGCAGGATGAAGGAGCGTTTCCAGGGTATCCAGGCCGTATCGGAGAACCTCTTTGGCCGAC
GGCTTCTCCTTCGTGAGACGCACGCCATGGGGTTGAACGACGGCCTCATCATCCCAGGCTCGTATTTCCCGCTGGGGACC
GGGCCGAATCGGGTCCGCAGCTTCGCCCTTGAGCGCCAGCCACTTCGGGGGCAAGTGCGCGTCATCGTCGTCCTCGTCGA
CTTCGAAGACAGGCCCATGAATCGAAGCCGGCAGGAATTCGAGGACCTGTTCTTCTCACAAGGGAAGATCCAGACAGGAA
GTGTGCGGGAATATTTCGAGGAGGCCAGTCATGGGCTCGTCGACATCGTGGGGCAGGTCGTCGGTCCGTATCGCATGCCT
TGCAAGCTGGCCCAGTACGCTGGGAACGGTTCGGGCACTGACAATCCGGAGCCCAACGCGCGGACCATGGCGAGGCATGC
CGCCGAAGCCGCGGCCAGCGTGGACTTCGCGCCCTACGACAACGATGGAAACGGCTTCGTCGACGCGTTCATCGTGGTCC
ACTCAGGCGGTGGCGCGGAGCAGACCGGCAGCGCTGGTGACATCTGGTCGCACAAGTGGGTTCTTGTCGGCGGGGAACAC
AATGCGCAGGGGGCGAAGATCTTCGGGTATTTGACCATCCCGGAGGATGCGAAGATTGGCGTCTGTTGCCATGAAATCGG
GCACCTCGTGTTCGGCTGGCCGGACCTGTACGACGCGGATGGCTCCTCGGAAGGGCTCGGGAACTGGTGCTTGATGGCGG
GTGGAAGCTGGAACAACAAAGGCGATGTCCCGGCCCATCCATCCGCTTGGTGCAAGGCCAGGCAGGGATGGGTCTCCATC
GTCAACTACACCGCCAACAAGAGCGTGAACTTCGCTGACGTCAAGACGGAGCACTCGGTGCACAGGCTTTGGAAGAACGG
GGTGCCGGGCTCCGAGTACTTCCTGGTCGAGAACCGCCAGCAGAACCAGTACGACAGATTCCTGCCGGGTTCGGGACTGC
TCGTGTATCACGTGGATGAGTCCATTCCGGACAATACGAACGAAGTCCATCCCAGAGTTCGCTTGGTTCAGGCGGATGCC
TTGGAGGACTTGGACCGTGCCGTCAACCGGGGCGACGACGGGGATCCATTCCCAGGTCGCTCTGGTAATGCTCGCTTTGA
TTTCAACACCCATCCGAGCTCCCGTTCGTATTCCGGGCGTGACAGTTGCGTGTCCATTTCCGACATCAGCCCTTCCGGGA
TGACAATGACGGCTCGTGTTGAAGTCAACAGGGCACAGAAAACCAGAGACGTCCTGCAGCAACTTGTCAATGACTGGCCT
GAGTGA

Upstream 100 bases:

>100_bases
CGAACCAGGGGTTGCTTCGAAGACAGCCCCCTCGCGGAGAAGGTTCTGGCACTGACTGTGCAGCTCAGACAGGAGCCAGG
ATGAGACAGTCGGACAAGAG

Downstream 100 bases:

>100_bases
GCACGCGGTGCTGGCCTCGAGGGATGACGCTTATGGTGCAGATTCAGGAGAACTGGGCCGATGTGAGGGGGCAAGTCCTC
TCATGGCGTCAGCAGAGTGA

Product: M6 family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MSGCQAWRKGWDMCSEHSPIERLCRVPPSPELRSRMKERFQGIQAVSENLFGRRLLLRETHAMGLNDGLIIPGSYFPLGT
GPNRVRSFALERQPLRGQVRVIVVLVDFEDRPMNRSRQEFEDLFFSQGKIQTGSVREYFEEASHGLVDIVGQVVGPYRMP
CKLAQYAGNGSGTDNPEPNARTMARHAAEAAASVDFAPYDNDGNGFVDAFIVVHSGGGAEQTGSAGDIWSHKWVLVGGEH
NAQGAKIFGYLTIPEDAKIGVCCHEIGHLVFGWPDLYDADGSSEGLGNWCLMAGGSWNNKGDVPAHPSAWCKARQGWVSI
VNYTANKSVNFADVKTEHSVHRLWKNGVPGSEYFLVENRQQNQYDRFLPGSGLLVYHVDESIPDNTNEVHPRVRLVQADA
LEDLDRAVNRGDDGDPFPGRSGNARFDFNTHPSSRSYSGRDSCVSISDISPSGMTMTARVEVNRAQKTRDVLQQLVNDWP
E

Sequences:

>Translated_481_residues
MSGCQAWRKGWDMCSEHSPIERLCRVPPSPELRSRMKERFQGIQAVSENLFGRRLLLRETHAMGLNDGLIIPGSYFPLGT
GPNRVRSFALERQPLRGQVRVIVVLVDFEDRPMNRSRQEFEDLFFSQGKIQTGSVREYFEEASHGLVDIVGQVVGPYRMP
CKLAQYAGNGSGTDNPEPNARTMARHAAEAAASVDFAPYDNDGNGFVDAFIVVHSGGGAEQTGSAGDIWSHKWVLVGGEH
NAQGAKIFGYLTIPEDAKIGVCCHEIGHLVFGWPDLYDADGSSEGLGNWCLMAGGSWNNKGDVPAHPSAWCKARQGWVSI
VNYTANKSVNFADVKTEHSVHRLWKNGVPGSEYFLVENRQQNQYDRFLPGSGLLVYHVDESIPDNTNEVHPRVRLVQADA
LEDLDRAVNRGDDGDPFPGRSGNARFDFNTHPSSRSYSGRDSCVSISDISPSGMTMTARVEVNRAQKTRDVLQQLVNDWP
E
>Mature_480_residues
SGCQAWRKGWDMCSEHSPIERLCRVPPSPELRSRMKERFQGIQAVSENLFGRRLLLRETHAMGLNDGLIIPGSYFPLGTG
PNRVRSFALERQPLRGQVRVIVVLVDFEDRPMNRSRQEFEDLFFSQGKIQTGSVREYFEEASHGLVDIVGQVVGPYRMPC
KLAQYAGNGSGTDNPEPNARTMARHAAEAAASVDFAPYDNDGNGFVDAFIVVHSGGGAEQTGSAGDIWSHKWVLVGGEHN
AQGAKIFGYLTIPEDAKIGVCCHEIGHLVFGWPDLYDADGSSEGLGNWCLMAGGSWNNKGDVPAHPSAWCKARQGWVSIV
NYTANKSVNFADVKTEHSVHRLWKNGVPGSEYFLVENRQQNQYDRFLPGSGLLVYHVDESIPDNTNEVHPRVRLVQADAL
EDLDRAVNRGDDGDPFPGRSGNARFDFNTHPSSRSYSGRDSCVSISDISPSGMTMTARVEVNRAQKTRDVLQQLVNDWPE

Specific function: Neutral metalloprotease that is secreted to degrade antibacterial proteins produced by the insect host for its defense (attacins and cecropins). Probably degrades some unknown crucial protein(s) too, since it is toxic when injected to insect larvae [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M6 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012300
- InterPro:   IPR008757 [H]

Pfam domain/function: PF05547 Peptidase_M6 [H]

EC number: NA

Molecular weight: Translated: 53251; Mature: 53120

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGCQAWRKGWDMCSEHSPIERLCRVPPSPELRSRMKERFQGIQAVSENLFGRRLLLRET
CCHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HAMGLNDGLIIPGSYFPLGTGPNRVRSFALERQPLRGQVRVIVVLVDFEDRPMNRSRQEF
HHCCCCCCEECCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCHHHHH
EDLFFSQGKIQTGSVREYFEEASHGLVDIVGQVVGPYRMPCKLAQYAGNGSGTDNPEPNA
HHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCH
RTMARHAAEAAASVDFAPYDNDGNGFVDAFIVVHSGGGAEQTGSAGDIWSHKWVLVGGEH
HHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCEEEECCCC
NAQGAKIFGYLTIPEDAKIGVCCHEIGHLVFGWPDLYDADGSSEGLGNWCLMAGGSWNNK
CCCCCEEEEEEECCCCCCEEHHHHHHCCCEECCCCCCCCCCCCCCCCCEEEEECCCCCCC
GDVPAHPSAWCKARQGWVSIVNYTANKSVNFADVKTEHSVHRLWKNGVPGSEYFLVENRQ
CCCCCCCHHHHHHHCCEEEEEEEECCCCCCCHHCCCHHHHHHHHHCCCCCCEEEEEECCC
QNQYDRFLPGSGLLVYHVDESIPDNTNEVHPRVRLVQADALEDLDRAVNRGDDGDPFPGR
CCCHHHCCCCCCEEEEEECCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCCCCC
SGNARFDFNTHPSSRSYSGRDSCVSISDISPSGMTMTARVEVNRAQKTRDVLQQLVNDWP
CCCEEEECCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEECHHHHHHHHHHHHHHHHCC
E
C
>Mature Secondary Structure 
SGCQAWRKGWDMCSEHSPIERLCRVPPSPELRSRMKERFQGIQAVSENLFGRRLLLRET
CHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HAMGLNDGLIIPGSYFPLGTGPNRVRSFALERQPLRGQVRVIVVLVDFEDRPMNRSRQEF
HHCCCCCCEECCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCHHHHH
EDLFFSQGKIQTGSVREYFEEASHGLVDIVGQVVGPYRMPCKLAQYAGNGSGTDNPEPNA
HHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCH
RTMARHAAEAAASVDFAPYDNDGNGFVDAFIVVHSGGGAEQTGSAGDIWSHKWVLVGGEH
HHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCEEEECCCC
NAQGAKIFGYLTIPEDAKIGVCCHEIGHLVFGWPDLYDADGSSEGLGNWCLMAGGSWNNK
CCCCCEEEEEEECCCCCCEEHHHHHHCCCEECCCCCCCCCCCCCCCCCEEEEECCCCCCC
GDVPAHPSAWCKARQGWVSIVNYTANKSVNFADVKTEHSVHRLWKNGVPGSEYFLVENRQ
CCCCCCCHHHHHHHCCEEEEEEEECCCCCCCHHCCCHHHHHHHHHCCCCCCEEEEEECCC
QNQYDRFLPGSGLLVYHVDESIPDNTNEVHPRVRLVQADALEDLDRAVNRGDDGDPFPGR
CCCHHHCCCCCCEEEEEECCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCCCCC
SGNARFDFNTHPSSRSYSGRDSCVSISDISPSGMTMTARVEVNRAQKTRDVLQQLVNDWP
CCCEEEECCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEECHHHHHHHHHHHHHHHHCC
E
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2089225; 6421577 [H]