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The map label for this gene is lip [H]

Identifier: 108756922

GI number: 108756922

Start: 6872775

End: 6873734

Strand: Direct

Name: lip [H]

Synonym: MXAN_5522

Alternate gene names: 108756922

Gene position: 6872775-6873734 (Clockwise)

Preceding gene: 108760692

Following gene: 108762888

Centisome position: 75.2

GC content: 66.77

Gene sequence:

>960_bases
GTGGACCCGTCCCCCGAACAGGAGCCCCTCCTCATGCGAAACGCTGTCCGGACACTGGTTCTGGCTGTCGCGGCACTTGG
CTTGTGGTCGCAACCCGCGCTCGCGAATACCCAAACGCAGACCCGCTATCCCATCGTGCTGGCGCACGGCATGGCGGGCT
TCGACTCGCTGTTTGGCGTCTACGACTACTTCTACGGCATCGGCTCCGACCTGCGCTCGGGCGGGGCGACGGTGTACGTG
ACGAGCGTTCCGCAGTTCAACACCACGGAGCAGCGTGGCGAGGCGCTGCTGGCGCAGGTGAAGGACATCGTCGCGCGCTC
GGGCAAGGGCAAGGTGAACCTCATTGGCCACAGCCACGGCGGCCTGGACGTGCGCTATGTGGCGGCGGTGCGCCCGGACC
TGGTGGCGTCCGTGACGACGGTGGGCTCTCCGCACAAGGGCGCGGACCTGGCGGACTACCTGCGCGCCAACCTCCGGGGC
GGCTCCTTCACGGAGAGCGTGCTGGCCTACTTCGCCAACAACCTGGGCACCGTCCTGGGGCTGCTGTCGGGGAAGACGAA
CCCGCAGGACGCCATTGGCGCGCTGGCGGCGCTCAGCAAGTCTGGCACGGCGGCGTTCAACCAGAAGTACCCGGCGGGCA
TCCCCTCCAGCAGTTGTGGCCAGGGCGCCGCGACGGGCACGCAGGGCCAGCGCTACTACTCCTGGTCCGGCACGGACCCC
TTCACCAACATGCTCGACGTGTCCGACTACCCGATGAAGCTGAGCTCGTTCTTCTACAGCGAGGCGAACGACGGCCTGGT
CGGCAAGTGCAGCTCGCACTTCGGCACGGTGTTGCGTGACAACTACGACATGAACCACCTGGACGAGGTGAACCAGGTGC
TGGGCCTCACCGCCTTCTTCACCAACCCGAAGACGGTGTTCCGCAACCATGCCAACCGCCTGAAGGGGCTCGGCCTCTAG

Upstream 100 bases:

>100_bases
GGATGCGACAACTGACCTCGCCCGGTTTACTGATAATGCGGGAGGCGCCTTGATTCTGGTCTGTGATTGGCCTACGCGTT
GACTCGCGGGTCAATCCGCA

Downstream 100 bases:

>100_bases
ACGGCCGCGCGCGAAGGACCGCCATGAAGAACCGCGCCGTCATTCCCGTAGCCGCGCTGTGCGCCCTGCTGGGTGCGGGC
GTGTTCTCATGGTGGAAGGC

Product: lactonizing lipase

Products: NA

Alternate protein names: Triacylglycerol lipase [H]

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MDPSPEQEPLLMRNAVRTLVLAVAALGLWSQPALANTQTQTRYPIVLAHGMAGFDSLFGVYDYFYGIGSDLRSGGATVYV
TSVPQFNTTEQRGEALLAQVKDIVARSGKGKVNLIGHSHGGLDVRYVAAVRPDLVASVTTVGSPHKGADLADYLRANLRG
GSFTESVLAYFANNLGTVLGLLSGKTNPQDAIGALAALSKSGTAAFNQKYPAGIPSSSCGQGAATGTQGQRYYSWSGTDP
FTNMLDVSDYPMKLSSFFYSEANDGLVGKCSSHFGTVLRDNYDMNHLDEVNQVLGLTAFFTNPKTVFRNHANRLKGLGL

Sequences:

>Translated_319_residues
MDPSPEQEPLLMRNAVRTLVLAVAALGLWSQPALANTQTQTRYPIVLAHGMAGFDSLFGVYDYFYGIGSDLRSGGATVYV
TSVPQFNTTEQRGEALLAQVKDIVARSGKGKVNLIGHSHGGLDVRYVAAVRPDLVASVTTVGSPHKGADLADYLRANLRG
GSFTESVLAYFANNLGTVLGLLSGKTNPQDAIGALAALSKSGTAAFNQKYPAGIPSSSCGQGAATGTQGQRYYSWSGTDP
FTNMLDVSDYPMKLSSFFYSEANDGLVGKCSSHFGTVLRDNYDMNHLDEVNQVLGLTAFFTNPKTVFRNHANRLKGLGL
>Mature_319_residues
MDPSPEQEPLLMRNAVRTLVLAVAALGLWSQPALANTQTQTRYPIVLAHGMAGFDSLFGVYDYFYGIGSDLRSGGATVYV
TSVPQFNTTEQRGEALLAQVKDIVARSGKGKVNLIGHSHGGLDVRYVAAVRPDLVASVTTVGSPHKGADLADYLRANLRG
GSFTESVLAYFANNLGTVLGLLSGKTNPQDAIGALAALSKSGTAAFNQKYPAGIPSSSCGQGAATGTQGQRYYSWSGTDP
FTNMLDVSDYPMKLSSFFYSEANDGLVGKCSSHFGTVLRDNYDMNHLDEVNQVLGLTAFFTNPKTVFRNHANRLKGLGL

Specific function: Catalyzes the hydrolysis of triglycerides. Catalyzes the synthesis of macrocyclic lactones in anhydrous organic solvents [H]

COG id: COG1075

COG function: function code R; Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold

Gene ontology:

Cell location: Cell surface. Secreted, extracellular space. Note=During early stationary growth phase about 10% of the enzyme molecules remain cell-bound while about 90% are released into the growth medium [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Pseudomonas lipase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320263, Length=174, Percent_Identity=31.0344827586207, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 33989; Mature: 33989

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: PS00120 LIPASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPSPEQEPLLMRNAVRTLVLAVAALGLWSQPALANTQTQTRYPIVLAHGMAGFDSLFGV
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHH
YDYFYGIGSDLRSGGATVYVTSVPQFNTTEQRGEALLAQVKDIVARSGKGKVNLIGHSHG
HHHHHHCCHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
GLDVRYVAAVRPDLVASVTTVGSPHKGADLADYLRANLRGGSFTESVLAYFANNLGTVLG
CCEEEEEEHHCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
LLSGKTNPQDAIGALAALSKSGTAAFNQKYPAGIPSSSCGQGAATGTQGQRYYSWSGTDP
HHCCCCCHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCC
FTNMLDVSDYPMKLSSFFYSEANDGLVGKCSSHFGTVLRDNYDMNHLDEVNQVLGLTAFF
HHHHHCCCCCCHHHHHHHHHCCCCCCEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHEE
TNPKTVFRNHANRLKGLGL
CCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDPSPEQEPLLMRNAVRTLVLAVAALGLWSQPALANTQTQTRYPIVLAHGMAGFDSLFGV
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHH
YDYFYGIGSDLRSGGATVYVTSVPQFNTTEQRGEALLAQVKDIVARSGKGKVNLIGHSHG
HHHHHHCCHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
GLDVRYVAAVRPDLVASVTTVGSPHKGADLADYLRANLRGGSFTESVLAYFANNLGTVLG
CCEEEEEEHHCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
LLSGKTNPQDAIGALAALSKSGTAAFNQKYPAGIPSSSCGQGAATGTQGQRYYSWSGTDP
HHCCCCCHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCC
FTNMLDVSDYPMKLSSFFYSEANDGLVGKCSSHFGTVLRDNYDMNHLDEVNQVLGLTAFF
HHHHHCCCCCCHHHHHHHHHCCCCCCEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHEE
TNPKTVFRNHANRLKGLGL
CCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1512563; 1632642; 1576157; 10984043; 1748875; 11133953 [H]