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The map label for this gene is tolQ [H]

Identifier: 108756839

GI number: 108756839

Start: 933959

End: 934639

Strand: Direct

Name: tolQ [H]

Synonym: MXAN_0818

Alternate gene names: 108756839

Gene position: 933959-934639 (Clockwise)

Preceding gene: 108760717

Following gene: 108762409

Centisome position: 10.22

GC content: 68.72

Gene sequence:

>681_bases
ATGCCGTCCATCGCCGTTTTCGCCCAGGCCCACCCGGAGCAACTGGGGTGGCTCAGCAGCAAGCTGCTGGGGGTGACGCT
CACTTCCGCGGAGTGGGTGCTGTGGGTGCTGGTGTGCCTGTCGGTGCTCTCCATCGCCATCATGCTGGAGCGCACGGTGT
ACTTCGCCCGTCACCGGCTGCCGGACTCGGAGGCGCTGGCGGTGCGGCTGTCGCGCGGTGAGCTGGACGCGGTGAAGGCC
GCCATCCAGGGGCGTCAGGGCATGGAGGCCGCCATCCTGCGTGAAGGGCTGGCGTGCGCCGACCAGGGCGCGGACACGGT
GGAGCAGGTGATTGCCTCCACCCTGTCGCGTGAGCGCCCACGCTACGAGCGCTTCCTGTCCTACCTGGGCACGCTGGGCA
ACAACGCGCCGTTCATCGGTCTGTTCGGCACGGTGCTGGGCATCATCAAGGCCTTCAATGACCTGGGGAAGATGAACGCC
CAGGGCGGCGGCGGGGCCATGCAGCAGACCGTCATGGCCGGCATCTCCGAAGCGCTCGTCGCCACGGCCGTGGGTCTGGC
GGTGGCGATTCCGGCGGTGGTGGCCTTCAACGTCTTCAGCCGTCAGCTCAAGACGCTCACCAGCCGCGCCAATGCCCTGG
GCCACGCGCTGGTGGGCAGTCTTCGCTCGGAGGCCCGTTAG

Upstream 100 bases:

>100_bases
CCGTCAGAGGGGCCCGGAAAAAATCCGACCACCAGGTGACACTTCAATTCGGGCCCGGTGTTCTGGTCGCGCCAACGTGC
TTCGCGAGGGGAAAGACACC

Downstream 100 bases:

>100_bases
GCCATGGCGGGCAGCGCGCAGGACAACGACGACGAAATCACCGGCATCAACGTCACCCCGCTGGTGGACGTGGTGCTGGT
GCTGCTCATCATCTTCATGG

Product: MotA/TolQ/ExbB proton channel family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MPSIAVFAQAHPEQLGWLSSKLLGVTLTSAEWVLWVLVCLSVLSIAIMLERTVYFARHRLPDSEALAVRLSRGELDAVKA
AIQGRQGMEAAILREGLACADQGADTVEQVIASTLSRERPRYERFLSYLGTLGNNAPFIGLFGTVLGIIKAFNDLGKMNA
QGGGGAMQQTVMAGISEALVATAVGLAVAIPAVVAFNVFSRQLKTLTSRANALGHALVGSLRSEAR

Sequences:

>Translated_226_residues
MPSIAVFAQAHPEQLGWLSSKLLGVTLTSAEWVLWVLVCLSVLSIAIMLERTVYFARHRLPDSEALAVRLSRGELDAVKA
AIQGRQGMEAAILREGLACADQGADTVEQVIASTLSRERPRYERFLSYLGTLGNNAPFIGLFGTVLGIIKAFNDLGKMNA
QGGGGAMQQTVMAGISEALVATAVGLAVAIPAVVAFNVFSRQLKTLTSRANALGHALVGSLRSEAR
>Mature_225_residues
PSIAVFAQAHPEQLGWLSSKLLGVTLTSAEWVLWVLVCLSVLSIAIMLERTVYFARHRLPDSEALAVRLSRGELDAVKAA
IQGRQGMEAAILREGLACADQGADTVEQVIASTLSRERPRYERFLSYLGTLGNNAPFIGLFGTVLGIIKAFNDLGKMNAQ
GGGGAMQQTVMAGISEALVATAVGLAVAIPAVVAFNVFSRQLKTLTSRANALGHALVGSLRSEAR

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=93, Percent_Identity=45.1612903225806, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789381, Length=179, Percent_Identity=35.195530726257, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014163 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 23977; Mature: 23846

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSIAVFAQAHPEQLGWLSSKLLGVTLTSAEWVLWVLVCLSVLSIAIMLERTVYFARHRL
CCCCHHHHHCCHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PDSEALAVRLSRGELDAVKAAIQGRQGMEAAILREGLACADQGADTVEQVIASTLSRERP
CCCHHHEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCH
RYERFLSYLGTLGNNAPFIGLFGTVLGIIKAFNDLGKMNAQGGGGAMQQTVMAGISEALV
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
ATAVGLAVAIPAVVAFNVFSRQLKTLTSRANALGHALVGSLRSEAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PSIAVFAQAHPEQLGWLSSKLLGVTLTSAEWVLWVLVCLSVLSIAIMLERTVYFARHRL
CCCHHHHHCCHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PDSEALAVRLSRGELDAVKAAIQGRQGMEAAILREGLACADQGADTVEQVIASTLSRERP
CCCHHHEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCH
RYERFLSYLGTLGNNAPFIGLFGTVLGIIKAFNDLGKMNAQGGGGAMQQTVMAGISEALV
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
ATAVGLAVAIPAVVAFNVFSRQLKTLTSRANALGHALVGSLRSEAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8955385; 10984043 [H]