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The map label for this gene is pdxJ [H]

Identifier: 108563955

GI number: 108563955

Start: 1590895

End: 1591683

Strand: Direct

Name: pdxJ [H]

Synonym: HPAG1_1530

Alternate gene names: 108563955

Gene position: 1590895-1591683 (Clockwise)

Preceding gene: 108563951

Following gene: 108563956

Centisome position: 99.66

GC content: 38.53

Gene sequence:

>789_bases
ATGCGTTTTGGATTGAATATTGATCACATTGTTACTTTAAGAGAGATAAGAAAAACTTACGAGCCTGAGATTTTAGAAGC
CTTATTCATCGCTAAAAACACCCATAAAGTGGATTTAATCACCATCCATTTGAGGGAAGACAAACGACACATTCAAAATG
AAGATGTTTTGAGGCTGCTTGAAATAAGCCCTTTGCCTATCAATATTGAATGCTCTATCAATGTAGCAATCACTGATTTT
TTATGCTCTTTAAAAAATAAGCCGAGTAAGGTTACAATCGTGCCTGAAAACAGAAATGAGGTTACGACAGAGGGGGGGTT
GGATTGCTCACTAAAGGGTTTAGGAGAGGTGATTAGAGCGTATCACAATAAAGGCATTGAAGTGTCTTTGTTTGTTGATC
CTTTAAAAGACGCTCTGCATTTTGCAAAGGAGCATCAAGTCAAGCAGGTGGAGTTCCACACTGGGGTGTATGCGAATTTA
CACAACGCTTTATATTCTAACGCTAACAATCAAATCCATGCCATTAGCGCGCTCAAAGACAAATGCCCCAAAGAATTGAA
AGAAGAATTGCACAACGCCTTTTTGCAATTAAGGAGGATGAGCAAAGAAGCGTTTTTTATGGGAATTGTGGTGTGCGCTG
GGCATGGGTTGAATTATACTAATGTGAAAGAATTGCTAAAAATCCCCTCTTTAAGAGAGCTTAATATCGGTCATAGCGTG
GTTTCAAAAGCGGTTTTAGTGGGATTAGAAAAAGCGATTTTAGAAATGGCACAACTTATCAAGCGATAA

Upstream 100 bases:

>100_bases
ATTATAGCAAAAGATAGCTTGATGATAAAATCTTATAGGTGTAAGAGGCGGGTTTTATGTTACAATTCCAAAAATCATTA
TTATAAAATAAAGGATAGCC

Downstream 100 bases:

>100_bases
AATGGCTAAAAAGAAAATTGCGATCAGTTGTGGGGATATTCAAGGCGTAGGCTTAGAATTGATTTTAAAAAGCCATAAGG
AAGTGAGTGCGTTTTGTGAG

Product: pyridoxine 5'-phosphate synthase

Products: NA

Alternate protein names: PNP synthase [H]

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MRFGLNIDHIVTLREIRKTYEPEILEALFIAKNTHKVDLITIHLREDKRHIQNEDVLRLLEISPLPINIECSINVAITDF
LCSLKNKPSKVTIVPENRNEVTTEGGLDCSLKGLGEVIRAYHNKGIEVSLFVDPLKDALHFAKEHQVKQVEFHTGVYANL
HNALYSNANNQIHAISALKDKCPKELKEELHNAFLQLRRMSKEAFFMGIVVCAGHGLNYTNVKELLKIPSLRELNIGHSV
VSKAVLVGLEKAILEMAQLIKR

Sequences:

>Translated_262_residues
MRFGLNIDHIVTLREIRKTYEPEILEALFIAKNTHKVDLITIHLREDKRHIQNEDVLRLLEISPLPINIECSINVAITDF
LCSLKNKPSKVTIVPENRNEVTTEGGLDCSLKGLGEVIRAYHNKGIEVSLFVDPLKDALHFAKEHQVKQVEFHTGVYANL
HNALYSNANNQIHAISALKDKCPKELKEELHNAFLQLRRMSKEAFFMGIVVCAGHGLNYTNVKELLKIPSLRELNIGHSV
VSKAVLVGLEKAILEMAQLIKR
>Mature_262_residues
MRFGLNIDHIVTLREIRKTYEPEILEALFIAKNTHKVDLITIHLREDKRHIQNEDVLRLLEISPLPINIECSINVAITDF
LCSLKNKPSKVTIVPENRNEVTTEGGLDCSLKGLGEVIRAYHNKGIEVSLFVDPLKDALHFAKEHQVKQVEFHTGVYANL
HNALYSNANNQIHAISALKDKCPKELKEELHNAFLQLRRMSKEAFFMGIVVCAGHGLNYTNVKELLKIPSLRELNIGHSV
VSKAVLVGLEKAILEMAQLIKR

Specific function: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate [H]

COG id: COG0854

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788917, Length=263, Percent_Identity=36.8821292775665, Blast_Score=159, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR004569 [H]

Pfam domain/function: PF03740 PdxJ [H]

EC number: =2.6.99.2 [H]

Molecular weight: Translated: 29663; Mature: 29663

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFGLNIDHIVTLREIRKTYEPEILEALFIAKNTHKVDLITIHLREDKRHIQNEDVLRLL
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEEEEECCHHHCCCHHHHHHH
EISPLPINIECSINVAITDFLCSLKNKPSKVTIVPENRNEVTTEGGLDCSLKGLGEVIRA
CCCCCEEEEEEEEEHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEHHHHHHHHHH
YHNKGIEVSLFVDPLKDALHFAKEHQVKQVEFHTGVYANLHNALYSNANNQIHAISALKD
HHCCCCEEEEEHHHHHHHHHHHHHCCHHEEEECCCHHHHHHHHHHCCCCCCEEHHHHHHH
KCPKELKEELHNAFLQLRRMSKEAFFMGIVVCAGHGLNYTNVKELLKIPSLRELNIGHSV
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCHHH
VSKAVLVGLEKAILEMAQLIKR
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRFGLNIDHIVTLREIRKTYEPEILEALFIAKNTHKVDLITIHLREDKRHIQNEDVLRLL
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEEEEECCHHHCCCHHHHHHH
EISPLPINIECSINVAITDFLCSLKNKPSKVTIVPENRNEVTTEGGLDCSLKGLGEVIRA
CCCCCEEEEEEEEEHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEHHHHHHHHHH
YHNKGIEVSLFVDPLKDALHFAKEHQVKQVEFHTGVYANLHNALYSNANNQIHAISALKD
HHCCCCEEEEEHHHHHHHHHHHHHCCHHEEEECCCHHHHHHHHHHCCCCCCEEHHHHHHH
KCPKELKEELHNAFLQLRRMSKEAFFMGIVVCAGHGLNYTNVKELLKIPSLRELNIGHSV
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCHHH
VSKAVLVGLEKAILEMAQLIKR
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA