Click here to switch to the map view.

The map label for this gene is tsf [H]

Identifier: 108563929

GI number: 108563929

Start: 1567563

End: 1568630

Strand: Direct

Name: tsf [H]

Synonym: HPAG1_1504

Alternate gene names: 108563929

Gene position: 1567563-1568630 (Clockwise)

Preceding gene: 108563928

Following gene: 108563934

Centisome position: 98.2

GC content: 40.82

Gene sequence:

>1068_bases
ATGTCAGGAATTAGCGCTCAATTAGTCAAAAAATTAAGGGACTTAACCGATGCGGGCATGATGGATTGCAAAAAAGCCCT
TGTAGAAGTGGCTGGGGATTTGCAAAAGGCTATTGATTTCTTGCGCGAAAAAGGCTTGAGTAAAGCCGCTAAAAAGGCCG
ATAGGATCGCTGCTGAGGGCGTAATCGCTTTAGAAGTGGCACCTGATTTTAAAAGCGCGATGATGGTAGAAATCAATAGC
GAAACGGATTTTGTGGCTAAAAATGAGGGCTTTAAGGAATTGGTGAAAAAAACTTTAGAAACAATCAAAGCCCACAATAT
CCATGCCACAGAAGAACTGCTTAAAAGCCCATTAGATAACAAGCCTTTTGAAGAATATTTGCACTCTCAAATCGCTGTGA
TTGGTGAAAACATTTTAGTGAGAAAAATCGCTCATTTAAAAGCCCCTAGCTCTCATATCATCAATGGCTATGCGCATTCT
AACGCCAGAGTGGGCGTGTTAATCGGTATAAAATACGATAATGAGAAAAACGCTCCAAAAGTGGTTGAACTGGCCCGAAA
CATCGCTATGCATGCCGCAGCGATGAAACCTCAAGTGCTAGATTGCAAAGACTTTAGCCTTGATTTTGTCAAAAAAGAAA
CTTTAGCTTTGATCGCTGAAATTGAAAAAGACAATGAAGAGGCCAAACGCTTGGGCAAACCTTTAAAAAACATCCCCACT
TTTGGGAGTCGCATTGAATTGAGCGATGAAGTTTTAGCCCATCAAAAGAAAGCTTTTGAAGACGAATTAAAAGCGCAAGG
CAAGCCTGAAAAAATCTGGGATAAAATCGTTCCTGGAAAGATGGAAAGGTTTATCGCTGATAACACCCTTATTGATCAAC
GCCTGACCCTTTTAGGGCAATTCTATGTCATGGACGATAAAAAAACTATCGCTCAAGTGGTTGCTGATTGCTCCAAAGAA
TGGGATGACGATTTAAAAATCACTGAGTATGTGCGTTTTGAATTGGGCGAAGGCATTGAGAAAAAGGCAGAGAATTTCGC
TGAAGAAGTGGCTTTGCAAATGAAGTGA

Upstream 100 bases:

>100_bases
ATGCGGATGAAAATAGCGAAGAGATAGAGTTCGTGAGCAATGAAGAAAAAGAAGAAATGCTCGCTGAAATCCAAAAAGAA
ATCACTCAAGGAGCCGAATA

Downstream 100 bases:

>100_bases
GATTTTAGCAAACAACCTTTAAAGGTTGTTTCTTCTAACCTTTCAACTTTCTTTATTTAAAATTTTCCATTTTAATGTGC
TTGAAATTTTTGTAATTTTC

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts [H]

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MSGISAQLVKKLRDLTDAGMMDCKKALVEVAGDLQKAIDFLREKGLSKAAKKADRIAAEGVIALEVAPDFKSAMMVEINS
ETDFVAKNEGFKELVKKTLETIKAHNIHATEELLKSPLDNKPFEEYLHSQIAVIGENILVRKIAHLKAPSSHIINGYAHS
NARVGVLIGIKYDNEKNAPKVVELARNIAMHAAAMKPQVLDCKDFSLDFVKKETLALIAEIEKDNEEAKRLGKPLKNIPT
FGSRIELSDEVLAHQKKAFEDELKAQGKPEKIWDKIVPGKMERFIADNTLIDQRLTLLGQFYVMDDKKTIAQVVADCSKE
WDDDLKITEYVRFELGEGIEKKAENFAEEVALQMK

Sequences:

>Translated_355_residues
MSGISAQLVKKLRDLTDAGMMDCKKALVEVAGDLQKAIDFLREKGLSKAAKKADRIAAEGVIALEVAPDFKSAMMVEINS
ETDFVAKNEGFKELVKKTLETIKAHNIHATEELLKSPLDNKPFEEYLHSQIAVIGENILVRKIAHLKAPSSHIINGYAHS
NARVGVLIGIKYDNEKNAPKVVELARNIAMHAAAMKPQVLDCKDFSLDFVKKETLALIAEIEKDNEEAKRLGKPLKNIPT
FGSRIELSDEVLAHQKKAFEDELKAQGKPEKIWDKIVPGKMERFIADNTLIDQRLTLLGQFYVMDDKKTIAQVVADCSKE
WDDDLKITEYVRFELGEGIEKKAENFAEEVALQMK
>Mature_354_residues
SGISAQLVKKLRDLTDAGMMDCKKALVEVAGDLQKAIDFLREKGLSKAAKKADRIAAEGVIALEVAPDFKSAMMVEINSE
TDFVAKNEGFKELVKKTLETIKAHNIHATEELLKSPLDNKPFEEYLHSQIAVIGENILVRKIAHLKAPSSHIINGYAHSN
ARVGVLIGIKYDNEKNAPKVVELARNIAMHAAAMKPQVLDCKDFSLDFVKKETLALIAEIEKDNEEAKRLGKPLKNIPTF
GSRIELSDEVLAHQKKAFEDELKAQGKPEKIWDKIVPGKMERFIADNTLIDQRLTLLGQFYVMDDKKTIAQVVADCSKEW
DDDLKITEYVRFELGEGIEKKAENFAEEVALQMK

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome [H]

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family [H]

Homologues:

Organism=Homo sapiens, GI171846268, Length=227, Percent_Identity=29.0748898678414, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1786366, Length=355, Percent_Identity=36.056338028169, Blast_Score=179, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17561440, Length=221, Percent_Identity=27.6018099547511, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449 [H]

Pfam domain/function: PF00889 EF_TS; PF00627 UBA [H]

EC number: NA

Molecular weight: Translated: 39698; Mature: 39567

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS01126 EF_TS_1 ; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGISAQLVKKLRDLTDAGMMDCKKALVEVAGDLQKAIDFLREKGLSKAAKKADRIAAEG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCC
VIALEVAPDFKSAMMVEINSETDFVAKNEGFKELVKKTLETIKAHNIHATEELLKSPLDN
EEEEEECCCCCCEEEEEECCCCCCEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCC
KPFEEYLHSQIAVIGENILVRKIAHLKAPSSHIINGYAHSNARVGVLIGIKYDNEKNAPK
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEECEECCCCEEEEEEEEEECCCCCCHH
VVELARNIAMHAAAMKPQVLDCKDFSLDFVKKETLALIAEIEKDNEEAKRLGKPLKNIPT
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHCCC
FGSRIELSDEVLAHQKKAFEDELKAQGKPEKIWDKIVPGKMERFIADNTLIDQRLTLLGQ
CCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHH
FYVMDDKKTIAQVVADCSKEWDDDLKITEYVRFELGEGIEKKAENFAEEVALQMK
HHEECCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SGISAQLVKKLRDLTDAGMMDCKKALVEVAGDLQKAIDFLREKGLSKAAKKADRIAAEG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCC
VIALEVAPDFKSAMMVEINSETDFVAKNEGFKELVKKTLETIKAHNIHATEELLKSPLDN
EEEEEECCCCCCEEEEEECCCCCCEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCC
KPFEEYLHSQIAVIGENILVRKIAHLKAPSSHIINGYAHSNARVGVLIGIKYDNEKNAPK
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEECEECCCCEEEEEEEEEECCCCCCHH
VVELARNIAMHAAAMKPQVLDCKDFSLDFVKKETLALIAEIEKDNEEAKRLGKPLKNIPT
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHCCC
FGSRIELSDEVLAHQKKAFEDELKAQGKPEKIWDKIVPGKMERFIADNTLIDQRLTLLGQ
CCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHH
FYVMDDKKTIAQVVADCSKEWDDDLKITEYVRFELGEGIEKKAENFAEEVALQMK
HHEECCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA