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The map label for this gene is fbp [H]

Identifier: 108563908

GI number: 108563908

Start: 1544211

End: 1545083

Strand: Direct

Name: fbp [H]

Synonym: HPAG1_1483

Alternate gene names: 108563908

Gene position: 1544211-1545083 (Clockwise)

Preceding gene: 108563905

Following gene: 108563909

Centisome position: 96.73

GC content: 37.0

Gene sequence:

>873_bases
ATGGATTACAAACATTTTAAAGGCAAGCATGCAAACATCGTTATAGAAATCATCAGTCTTTTAGAAAAAGGGGTTAAAAA
AGCCCAAGAGATTTTAGAAAAGCCAGACGCTGGGAGTTACACTAAATTAGAAAACAGCAGCGGGGATACGCCTATTAAAG
CAGATTTAGCCCTAGACAAATTTTTAGAAGAAAATTTTTTGAGTTTAGAAAACATCAAAAGCGTTTTTAGCGAAGAAAAA
GAAACGCCTGTTACTAAAGAAAACGGCTCTTATTTGATCGCTTATGACCCCTTAGACGGGAGTTCAGTGATGGAGGCGAA
TTTCTTAGTAGGCACGATTATAGGGATTTATGAAAAGGATTATAAGGCGCAAAATTTAGTTGCAAGCCTTTATGTGGTTT
TTGGGCATAAAATAGAATTAATGGTGGCTTTAGAAGAAGTTTATCGTTACGCGTTTTACCAGAACAAGTTCCATTTTATA
GAAACCATCGTTTTAGAAAATAAGGGTAAAATCGTTGCTAGCGGAGGCAATCAAAAGGATTTTTCTTTGGGCTTGAAAAA
GGCTTTAGAAGGGTTTTTTGCAGAAAATTACCGCTTACGATACTCAGGATCTATGGTGGCTGATGTCCATCATGTGCTCA
TTAAAAAGGGCGGAATGTTTTCCTACCCGCAAAAGAAATTGCGAAAGCTTTTTGAAGTCTTTCCTTTAGCCTTGATCATC
GAAAAAGCTAAAGGGGAAGCGTTTTATTTTGATAAGGGGGTTAAAAAGCGTTTGCTAGAGCAAAGCGTAGAAAGCTACCA
TGAAAAAAGCGAATGCTATTTAGCCAGCCCACATGAAGCTCAAATTTTAGAAAAACATTTAAAGGGAGAATGA

Upstream 100 bases:

>100_bases
AGCGCTCAAAAGGCTCGGAGCTACTTTCAAAATACTTCCCTATTTCCAATGTTTTCAAGTAAAATATTAGCATCTTTAAT
CAAATCATAAAAGGGTTTTT

Downstream 100 bases:

>100_bases
TGCAAAATAGCGCTAAAAAATTAGAATATGAAGAGCGTTTTAATGACGCTCTTTTGAAATTACAAGCATGCCAAGAAGAA
AAGCAGGTAGCGAGTTGCTT

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MDYKHFKGKHANIVIEIISLLEKGVKKAQEILEKPDAGSYTKLENSSGDTPIKADLALDKFLEENFLSLENIKSVFSEEK
ETPVTKENGSYLIAYDPLDGSSVMEANFLVGTIIGIYEKDYKAQNLVASLYVVFGHKIELMVALEEVYRYAFYQNKFHFI
ETIVLENKGKIVASGGNQKDFSLGLKKALEGFFAENYRLRYSGSMVADVHHVLIKKGGMFSYPQKKLRKLFEVFPLALII
EKAKGEAFYFDKGVKKRLLEQSVESYHEKSECYLASPHEAQILEKHLKGE

Sequences:

>Translated_290_residues
MDYKHFKGKHANIVIEIISLLEKGVKKAQEILEKPDAGSYTKLENSSGDTPIKADLALDKFLEENFLSLENIKSVFSEEK
ETPVTKENGSYLIAYDPLDGSSVMEANFLVGTIIGIYEKDYKAQNLVASLYVVFGHKIELMVALEEVYRYAFYQNKFHFI
ETIVLENKGKIVASGGNQKDFSLGLKKALEGFFAENYRLRYSGSMVADVHHVLIKKGGMFSYPQKKLRKLFEVFPLALII
EKAKGEAFYFDKGVKKRLLEQSVESYHEKSECYLASPHEAQILEKHLKGE
>Mature_290_residues
MDYKHFKGKHANIVIEIISLLEKGVKKAQEILEKPDAGSYTKLENSSGDTPIKADLALDKFLEENFLSLENIKSVFSEEK
ETPVTKENGSYLIAYDPLDGSSVMEANFLVGTIIGIYEKDYKAQNLVASLYVVFGHKIELMVALEEVYRYAFYQNKFHFI
ETIVLENKGKIVASGGNQKDFSLGLKKALEGFFAENYRLRYSGSMVADVHHVLIKKGGMFSYPQKKLRKLFEVFPLALII
EKAKGEAFYFDKGVKKRLLEQSVESYHEKSECYLASPHEAQILEKHLKGE

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family [H]

Homologues:

Organism=Homo sapiens, GI189083692, Length=320, Percent_Identity=29.0625, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI16579888, Length=320, Percent_Identity=29.0625, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI22907028, Length=313, Percent_Identity=28.1150159744409, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1790679, Length=284, Percent_Identity=28.8732394366197, Blast_Score=89, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17508131, Length=311, Percent_Identity=27.9742765273312, Blast_Score=82, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6323409, Length=275, Percent_Identity=29.8181818181818, Blast_Score=95, Evalue=1e-20,
Organism=Drosophila melanogaster, GI45550998, Length=231, Percent_Identity=29.8701298701299, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI19921562, Length=231, Percent_Identity=29.8701298701299, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000146
- InterPro:   IPR023079 [H]

Pfam domain/function: PF00316 FBPase [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 32944; Mature: 32944

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYKHFKGKHANIVIEIISLLEKGVKKAQEILEKPDAGSYTKLENSSGDTPIKADLALDK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCEEHHHHHHH
FLEENFLSLENIKSVFSEEKETPVTKENGSYLIAYDPLDGSSVMEANFLVGTIIGIYEKD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCC
YKAQNLVASLYVVFGHKIELMVALEEVYRYAFYQNKFHFIETIVLENKGKIVASGGNQKD
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHEEEEECCCEEEECCCCCCH
FSLGLKKALEGFFAENYRLRYSGSMVADVHHVLIKKGGMFSYPQKKLRKLFEVFPLALII
HHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
EKAKGEAFYFDKGVKKRLLEQSVESYHEKSECYLASPHEAQILEKHLKGE
HHCCCCEEEECHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHCCC
>Mature Secondary Structure
MDYKHFKGKHANIVIEIISLLEKGVKKAQEILEKPDAGSYTKLENSSGDTPIKADLALDK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCEEHHHHHHH
FLEENFLSLENIKSVFSEEKETPVTKENGSYLIAYDPLDGSSVMEANFLVGTIIGIYEKD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCC
YKAQNLVASLYVVFGHKIELMVALEEVYRYAFYQNKFHFIETIVLENKGKIVASGGNQKD
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHEEEEECCCEEEECCCCCCH
FSLGLKKALEGFFAENYRLRYSGSMVADVHHVLIKKGGMFSYPQKKLRKLFEVFPLALII
HHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
EKAKGEAFYFDKGVKKRLLEQSVESYHEKSECYLASPHEAQILEKHLKGE
HHCCCCEEEECHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA