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The map label for this gene is ppnK [H]

Identifier: 108563901

GI number: 108563901

Start: 1537852

End: 1538706

Strand: Direct

Name: ppnK [H]

Synonym: HPAG1_1476

Alternate gene names: 108563901

Gene position: 1537852-1538706 (Clockwise)

Preceding gene: 108563899

Following gene: 108563902

Centisome position: 96.33

GC content: 40.94

Gene sequence:

>855_bases
ATGAAAGATTCATATCAAACTATCGGCGTGTTTGTGCGGCCTACCCATTATCAAAACCCCCTTTTTGAAGAGCTAGAGCA
GGCTAAAGAATGGGTTTTAAAGCTTTTAGAAGATGAAGGGTTTGAAAGCTTTATGATTGATAGCCTTGATGGGGCAAAAG
ATGCACGATTGATAGAAAAAGCTTATGCGTTTTTGTGTTTAGGGGGCGATGGCACGATTTTAGGGGCGTTAAGAATGACG
CATTCTTACAATAAGCCGTGTTTTGGGGTTAGAATAGGGAATTTAGGGTTTTTGAGCGCGGTTGAATTGAATGGGTTGAA
AGATTTCTTACAAGATCTCAAGCAAAACAGGATCAAATTAGAAGAACATCTGGCTTTAGAGGGCCGTATCGGGAAAACCT
CTTTTTATGCGATCAATGAAATTGTGATCGCTAAAAAAAAAGCTTTAGGGGTTTTAGATATCAAAGCTTATGTGGGCCAT
ACGCCCTTTAACACCTATAAAGGCGATGGGCTTATCATTGCCACGCCCCTAGGCTCGACCGCTTATAATTTGAGTGCTCA
TGGGCCGATTGTGCATGCTTTAAGCCAAAGCTATATTTTAACGCCCTTGTGCGATTTTTCTTTAACGCAACGCCCTTTAG
TGCTAGGAGCGGAATTTTGCTTGAATTTTTGCGCTCATGAAGATGCTCTTGTAGTCATTGATGGGCAAGCCACTTACGAT
TTGAAAGCTAACCAACCCCTATACATTCAAAAAAGCCCCACGACCACCAAGCTCTTACAAAAAAATTCAAGGGATTATTT
TAAAGTGCTTAAAGAAAAGCTCTTATGGGGGGAAAGCCCTAGCAAAAAAAGATAA

Upstream 100 bases:

>100_bases
AAAATAAAAACTTCTTATGAATTCCACATAAGATGATAAAAAAGCGGCTAAAACCCACTTTTTTAAAATTTTGTTTCAAG
CTTTAAGCTACAATATACGC

Downstream 100 bases:

>100_bases
AAAGGGTAAAACATGCGAGATTTTAATAACGCTCAAATCACACGCTTAAAAGTGCGTCAAAACGCTGTTTTTGAAAAATT
GGATTTGGAGTTTAAAGACG

Product: hypothetical protein

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MKDSYQTIGVFVRPTHYQNPLFEELEQAKEWVLKLLEDEGFESFMIDSLDGAKDARLIEKAYAFLCLGGDGTILGALRMT
HSYNKPCFGVRIGNLGFLSAVELNGLKDFLQDLKQNRIKLEEHLALEGRIGKTSFYAINEIVIAKKKALGVLDIKAYVGH
TPFNTYKGDGLIIATPLGSTAYNLSAHGPIVHALSQSYILTPLCDFSLTQRPLVLGAEFCLNFCAHEDALVVIDGQATYD
LKANQPLYIQKSPTTTKLLQKNSRDYFKVLKEKLLWGESPSKKR

Sequences:

>Translated_284_residues
MKDSYQTIGVFVRPTHYQNPLFEELEQAKEWVLKLLEDEGFESFMIDSLDGAKDARLIEKAYAFLCLGGDGTILGALRMT
HSYNKPCFGVRIGNLGFLSAVELNGLKDFLQDLKQNRIKLEEHLALEGRIGKTSFYAINEIVIAKKKALGVLDIKAYVGH
TPFNTYKGDGLIIATPLGSTAYNLSAHGPIVHALSQSYILTPLCDFSLTQRPLVLGAEFCLNFCAHEDALVVIDGQATYD
LKANQPLYIQKSPTTTKLLQKNSRDYFKVLKEKLLWGESPSKKR
>Mature_284_residues
MKDSYQTIGVFVRPTHYQNPLFEELEQAKEWVLKLLEDEGFESFMIDSLDGAKDARLIEKAYAFLCLGGDGTILGALRMT
HSYNKPCFGVRIGNLGFLSAVELNGLKDFLQDLKQNRIKLEEHLALEGRIGKTSFYAINEIVIAKKKALGVLDIKAYVGH
TPFNTYKGDGLIIATPLGSTAYNLSAHGPIVHALSQSYILTPLCDFSLTQRPLVLGAEFCLNFCAHEDALVVIDGQATYD
LKANQPLYIQKSPTTTKLLQKNSRDYFKVLKEKLLWGESPSKKR

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=250, Percent_Identity=25.2, Blast_Score=75, Evalue=9e-14,
Organism=Escherichia coli, GI1788968, Length=291, Percent_Identity=26.4604810996564, Blast_Score=107, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6320794, Length=244, Percent_Identity=24.5901639344262, Blast_Score=97, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6325068, Length=222, Percent_Identity=28.8288288288288, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6322509, Length=237, Percent_Identity=25.7383966244726, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI28573832, Length=276, Percent_Identity=27.1739130434783, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI28573828, Length=262, Percent_Identity=27.4809160305344, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI28573826, Length=268, Percent_Identity=27.2388059701493, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI28573830, Length=282, Percent_Identity=26.9503546099291, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI161077047, Length=262, Percent_Identity=27.4809160305344, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI20129957, Length=281, Percent_Identity=24.5551601423488, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281363321, Length=281, Percent_Identity=24.5551601423488, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24653424, Length=287, Percent_Identity=24.390243902439, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281363323, Length=282, Percent_Identity=24.468085106383, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24653422, Length=287, Percent_Identity=24.390243902439, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 31724; Mature: 31724

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDSYQTIGVFVRPTHYQNPLFEELEQAKEWVLKLLEDEGFESFMIDSLDGAKDARLIEK
CCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHH
AYAFLCLGGDGTILGALRMTHSYNKPCFGVRIGNLGFLSAVELNGLKDFLQDLKQNRIKL
HEEEEEECCCCEEEEEEEHHCCCCCCEEEEEECCCCEEEHEECCCHHHHHHHHHHHHHHH
EEHLALEGRIGKTSFYAINEIVIAKKKALGVLDIKAYVGHTPFNTYKGDGLIIATPLGST
HHHEEECCCCCCCHHHHHHHHEEEHHHHCCEEEEHHHHCCCCCCCCCCCCEEEEECCCCC
AYNLSAHGPIVHALSQSYILTPLCDFSLTQRPLVLGAEFCLNFCAHEDALVVIDGQATYD
EEECCCCCHHHHHHCCCEEECCCCCCCCCCCCCEEEHHHHHHHHCCCCCEEEECCCEEEE
LKANQPLYIQKSPTTTKLLQKNSRDYFKVLKEKLLWGESPSKKR
ECCCCCEEEECCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKDSYQTIGVFVRPTHYQNPLFEELEQAKEWVLKLLEDEGFESFMIDSLDGAKDARLIEK
CCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHH
AYAFLCLGGDGTILGALRMTHSYNKPCFGVRIGNLGFLSAVELNGLKDFLQDLKQNRIKL
HEEEEEECCCCEEEEEEEHHCCCCCCEEEEEECCCCEEEHEECCCHHHHHHHHHHHHHHH
EEHLALEGRIGKTSFYAINEIVIAKKKALGVLDIKAYVGHTPFNTYKGDGLIIATPLGST
HHHEEECCCCCCCHHHHHHHHEEEHHHHCCEEEEHHHHCCCCCCCCCCCCEEEEECCCCC
AYNLSAHGPIVHALSQSYILTPLCDFSLTQRPLVLGAEFCLNFCAHEDALVVIDGQATYD
EEECCCCCHHHHHHCCCEEECCCCCCCCCCCCCEEEHHHHHHHHCCCCCEEEECCCEEEE
LKANQPLYIQKSPTTTKLLQKNSRDYFKVLKEKLLWGESPSKKR
ECCCCCEEEECCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA