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The map label for this gene is yciL [C]

Identifier: 108563881

GI number: 108563881

Start: 1515834

End: 1516622

Strand: Direct

Name: yciL [C]

Synonym: HPAG1_1456

Alternate gene names: 108563881

Gene position: 1515834-1516622 (Clockwise)

Preceding gene: 108563880

Following gene: 108563882

Centisome position: 94.96

GC content: 41.83

Gene sequence:

>789_bases
GTGGAGGGATTTAGCTTGAGAATCAACCAGTTTTTAGCCCACTACACCAAGCACTCAAGAAGAGAGGCTGAAAAATTGGT
TTTAGAAGGGCGGGTGAAAATCAACCATGAGCATGCAAAACTCGCTAGCGTGGTTAAAGAAAACGACAAGGTGTTTTTAG
ACAAACGACTCATTAAGCCCTTAAAAAACAAAAAATTCAGCGTGCTGGTTTATCACAAGCCAAAGGGCGAATTGGTGAGT
AAGGCCGATCCCTTAAAACGGCGCGTGATTTATGAAAGCTTGGAGAAAAAATACGCCCATTTCGCGCCGGTGGGGCGTTT
GGATTTTGCGAGCGAGGGGGTGTTATTATTAAGCGATAGTAAGGCGGTGGTGAGCACTTTAATGCATGCGAATTTAGAAA
AAGAATATCTTGTTAAGATTCAAGGTTTTGTTACAAGAGAGATGGAAAACGCTATGCAAGAGGGCTTGAAATTAGAAAAC
GCTACTAAGGGAGCGCACCAAAAAACCCCCATTAAAAGCATGGAATTTGCCCCCTTTATTGGTTATGAAATCATCAAAAA
CCATGCCAAATACTCTAAGCTTAGAGTCATCATCAATGAAGGGAAAAACAGAGAACTAAGGCGTTTTTTTGCGTTTTTTA
ACGCTGGAGTGTTGGATTTAAGGCGCGTTCGTTATGGTTTTGTGAATTTGAATGCCTTGCCGGTAGGGAAAATGCGTTTT
CTAAACCGCCAAGAATACAACGAACTGCATGCGTTTATGGCTAATAGGGCTAATACTAAAGGGGATTAG

Upstream 100 bases:

>100_bases
GCCCCTTGTATTTGATCATCAAAGATAAGGATAAGCAATTCAAAATCCAAAGCGATTTAATGGTAAATGAAAAGATTAAG
GACGATTTTAAAGGGTTAGA

Downstream 100 bases:

>100_bases
CGCTTGAGTTATGCTATACTTCGGCGGTTGGGGGAAATAAAAATTAAGGATTATCATGTTAGAAGTGATTAACGGGAAGA
ATTACGCAGAGAAAATCGCT

Product: hypothetical protein

Products: NA

Alternate protein names: RNA pseudouridylate synthase; RNA-uridine isomerase [H]

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MEGFSLRINQFLAHYTKHSRREAEKLVLEGRVKINHEHAKLASVVKENDKVFLDKRLIKPLKNKKFSVLVYHKPKGELVS
KADPLKRRVIYESLEKKYAHFAPVGRLDFASEGVLLLSDSKAVVSTLMHANLEKEYLVKIQGFVTREMENAMQEGLKLEN
ATKGAHQKTPIKSMEFAPFIGYEIIKNHAKYSKLRVIINEGKNRELRRFFAFFNAGVLDLRRVRYGFVNLNALPVGKMRF
LNRQEYNELHAFMANRANTKGD

Sequences:

>Translated_262_residues
MEGFSLRINQFLAHYTKHSRREAEKLVLEGRVKINHEHAKLASVVKENDKVFLDKRLIKPLKNKKFSVLVYHKPKGELVS
KADPLKRRVIYESLEKKYAHFAPVGRLDFASEGVLLLSDSKAVVSTLMHANLEKEYLVKIQGFVTREMENAMQEGLKLEN
ATKGAHQKTPIKSMEFAPFIGYEIIKNHAKYSKLRVIINEGKNRELRRFFAFFNAGVLDLRRVRYGFVNLNALPVGKMRF
LNRQEYNELHAFMANRANTKGD
>Mature_262_residues
MEGFSLRINQFLAHYTKHSRREAEKLVLEGRVKINHEHAKLASVVKENDKVFLDKRLIKPLKNKKFSVLVYHKPKGELVS
KADPLKRRVIYESLEKKYAHFAPVGRLDFASEGVLLLSDSKAVVSTLMHANLEKEYLVKIQGFVTREMENAMQEGLKLEN
ATKGAHQKTPIKSMEFAPFIGYEIIKNHAKYSKLRVIINEGKNRELRRFFAFFNAGVLDLRRVRYGFVNLNALPVGKMRF
LNRQEYNELHAFMANRANTKGD

Specific function: Unknown

COG id: COG1187

COG function: function code J; 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787524, Length=258, Percent_Identity=30.6201550387597, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790453, Length=256, Percent_Identity=28.515625, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006145
- InterPro:   IPR000748
- InterPro:   IPR018496
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 30303; Mature: 30303

Theoretical pI: Translated: 10.62; Mature: 10.62

Prosite motif: PS50889 S4 ; PS01149 PSI_RSU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGFSLRINQFLAHYTKHSRREAEKLVLEGRVKINHEHAKLASVVKENDKVFLDKRLIKP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHHHHCCCCEEHHHHHHHH
LKNKKFSVLVYHKPKGELVSKADPLKRRVIYESLEKKYAHFAPVGRLDFASEGVLLLSDS
HCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECC
KAVVSTLMHANLEKEYLVKIQGFVTREMENAMQEGLKLENATKGAHQKTPIKSMEFAPFI
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHH
GYEIIKNHAKYSKLRVIINEGKNRELRRFFAFFNAGVLDLRRVRYGFVNLNALPVGKMRF
HHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHCEEEECCCCCHHHHH
LNRQEYNELHAFMANRANTKGD
HHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEGFSLRINQFLAHYTKHSRREAEKLVLEGRVKINHEHAKLASVVKENDKVFLDKRLIKP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHHHHCCCCEEHHHHHHHH
LKNKKFSVLVYHKPKGELVSKADPLKRRVIYESLEKKYAHFAPVGRLDFASEGVLLLSDS
HCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECC
KAVVSTLMHANLEKEYLVKIQGFVTREMENAMQEGLKLENATKGAHQKTPIKSMEFAPFI
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHH
GYEIIKNHAKYSKLRVIINEGKNRELRRFFAFFNAGVLDLRRVRYGFVNLNALPVGKMRF
HHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHCEEEECCCCCHHHHH
LNRQEYNELHAFMANRANTKGD
HHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]