Click here to switch to the map view.

The map label for this gene is glmS [H]

Identifier: 108563809

GI number: 108563809

Start: 1432919

End: 1434712

Strand: Reverse

Name: glmS [H]

Synonym: HPAG1_1384

Alternate gene names: 108563809

Gene position: 1434712-1432919 (Counterclockwise)

Preceding gene: 108563810

Following gene: 108563808

Centisome position: 89.87

GC content: 40.86

Gene sequence:

>1794_bases
ATGTGTGGGATTGTAGGTTATATAGGGGATAGTGAGAAAAAATCTATTCTTTTAGAGGGCTTAAAGGAATTAGAATACAG
AGGCTATGACAGTGCTGGCTTAGCCGTATTGAGCAATGATTGTTTGGAAGTGTTTAAAACTCAAGGGAAATTAGAAAACC
TTAAATCAGAGCTTAAAAATAAAGAGTTTTTGGATTTTGGCGTGAGTATCGCTCACACCAGATGGGCCACGCATGGCAAG
CCAAGCAGCGCGAACGCCCACCCGCATTTTACAGAAAATTTAGCCTTGGTGCATAATGGTATCATTGAAAATCACGCGAG
CTTGAAAAAAGAATTAGAAAATAAAGGGCATGCGTTTTTAAGCCAAACGGACACGGAAGTCATTGCGCATTTATTAGAAG
AAACGCTTAAAAGCGAGAGCGATTTATTGAAAGCTTTTGAAAAAAGCATCAGCCTTTTAAAAGGGAGTTATGCGATTTTA
ATGCTCCATAAAAGGGCTAAAGAGAGCCTCTTTTACGCTAAATCTTCTTCGCCTTTAGTTGTGGGTAAGGGCAAAGAGGG
GGTGTTTTTTGCGTCCAGTTTGAGCGTGCTAGCCCCTAAAGTGGATCAATTTATCATCTTAGAAGAAAACAGCGTGGGGC
AGATTTCTTTAGAAAATTTTAAAGATTTAAAACATATTGAAAACATGAAAGATTACGCTTTTGAGAATAAAGATCATTCT
AAAGGGGATTTTAGGAATTATTTAGAAAAAGAGATTTATGAGCAGCACAGCAGTTTGCTAGAGTGTTTAGAGGGGCGCTT
GGAAGCCTTGAATGTGTATTGCGAGATCGATCCTGAATTTTTGGAAAATGTGAATGAAATCACGCTGTGTTCTTGCGGGA
GCAGTTACCATGCGAGTTTGGCGAGCGTGTATTTGTTTGAAAGGTTAGCCAAAATAAGAGCGAGGGCCATTTTAGCGAGC
GAATACCGCTACGCCCATTTTAAAAGCAACCCTAACGAGCTTTTTATAGCGATTTCTCAAAGCGGCGAAACCGCTGACAC
TTTGGAGGCTTTAAAATTAGCCAAAGCCCAAGGGCTTAAAACCATTAGCTTGTGTAACGCTCCTTTTAGCATGATGAGCC
GCATTAGCGATCATGTGCTTTTGATCAGAGCGGGGGTGGAAAGAAGCGTGGCATCCACTAAGGCGTTTTCTTCGCAAGTG
ATGCTTTTATGGCTTTTGAGCGTGTATCTAGGCAAACAATTAGGGACCATCTCTAAAGAAGAAGAAAGAATCCAAGCCAA
AAACATGCTCAATAGCGTGAATGCGATGAAAGTAGAGCCCAAATTGCATGAAAAAATCAAGCGCTTATCCAAACGCTACT
TGCATGGGCATGGCTTTTTTTATATTGGCCGTGATGTGTTTTACCCGCTCGCTTTAGAAGGAGCGTTGAAACTCAAAGAA
ATCAGCTACTTGCATGCTGAGGGTTATGCGAGCGCGGAGATGAAGCATGGGCCTATTGCGTTAGTGGATTCTAACCTTTT
TACCATTGCTTTATTGTCTAAGCATCTGTTATTTGATAAAACCAAAAGCAATATTGAAGAGTTGAGCGCTAGGGATTCTA
CGATTTGCGTGTTAAGCTCTGAAATTTTAGAGATCGCTGATGATTTTATCCAATTAGAAGAGAGCGAAAGCTATATGGAA
GAATTTTTCCGCATGAATTTAGCGGTGCAGCTTTTAGCCTTAGAAATCGCTATGCGTTTGAACCACGATGTGGATCACCC
AAGAAACTTAGCTAAAAGCGTTACCGTGGAATAA

Upstream 100 bases:

>100_bases
GAATGAAGCGTTTTTTACGCAACTAAGCGAAGAAGTGGAGCGTTTAAAGGAACTTATTAACGCTTTAAATAAGATCAAAA
AAGGGTTATTGGTGTTTTAA

Downstream 100 bases:

>100_bases
AAAGCGATTAGGAGTCAAATAATGGAAGTGATTTGTAAGCACTACACCCCTTTAGACATTGCAAGCCAAGCGATCCGCAC
TTGCTGGCAGAGCTTTGAAT

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 597; Mature: 597

Protein sequence:

>597_residues
MCGIVGYIGDSEKKSILLEGLKELEYRGYDSAGLAVLSNDCLEVFKTQGKLENLKSELKNKEFLDFGVSIAHTRWATHGK
PSSANAHPHFTENLALVHNGIIENHASLKKELENKGHAFLSQTDTEVIAHLLEETLKSESDLLKAFEKSISLLKGSYAIL
MLHKRAKESLFYAKSSSPLVVGKGKEGVFFASSLSVLAPKVDQFIILEENSVGQISLENFKDLKHIENMKDYAFENKDHS
KGDFRNYLEKEIYEQHSSLLECLEGRLEALNVYCEIDPEFLENVNEITLCSCGSSYHASLASVYLFERLAKIRARAILAS
EYRYAHFKSNPNELFIAISQSGETADTLEALKLAKAQGLKTISLCNAPFSMMSRISDHVLLIRAGVERSVASTKAFSSQV
MLLWLLSVYLGKQLGTISKEEERIQAKNMLNSVNAMKVEPKLHEKIKRLSKRYLHGHGFFYIGRDVFYPLALEGALKLKE
ISYLHAEGYASAEMKHGPIALVDSNLFTIALLSKHLLFDKTKSNIEELSARDSTICVLSSEILEIADDFIQLEESESYME
EFFRMNLAVQLLALEIAMRLNHDVDHPRNLAKSVTVE

Sequences:

>Translated_597_residues
MCGIVGYIGDSEKKSILLEGLKELEYRGYDSAGLAVLSNDCLEVFKTQGKLENLKSELKNKEFLDFGVSIAHTRWATHGK
PSSANAHPHFTENLALVHNGIIENHASLKKELENKGHAFLSQTDTEVIAHLLEETLKSESDLLKAFEKSISLLKGSYAIL
MLHKRAKESLFYAKSSSPLVVGKGKEGVFFASSLSVLAPKVDQFIILEENSVGQISLENFKDLKHIENMKDYAFENKDHS
KGDFRNYLEKEIYEQHSSLLECLEGRLEALNVYCEIDPEFLENVNEITLCSCGSSYHASLASVYLFERLAKIRARAILAS
EYRYAHFKSNPNELFIAISQSGETADTLEALKLAKAQGLKTISLCNAPFSMMSRISDHVLLIRAGVERSVASTKAFSSQV
MLLWLLSVYLGKQLGTISKEEERIQAKNMLNSVNAMKVEPKLHEKIKRLSKRYLHGHGFFYIGRDVFYPLALEGALKLKE
ISYLHAEGYASAEMKHGPIALVDSNLFTIALLSKHLLFDKTKSNIEELSARDSTICVLSSEILEIADDFIQLEESESYME
EFFRMNLAVQLLALEIAMRLNHDVDHPRNLAKSVTVE
>Mature_597_residues
MCGIVGYIGDSEKKSILLEGLKELEYRGYDSAGLAVLSNDCLEVFKTQGKLENLKSELKNKEFLDFGVSIAHTRWATHGK
PSSANAHPHFTENLALVHNGIIENHASLKKELENKGHAFLSQTDTEVIAHLLEETLKSESDLLKAFEKSISLLKGSYAIL
MLHKRAKESLFYAKSSSPLVVGKGKEGVFFASSLSVLAPKVDQFIILEENSVGQISLENFKDLKHIENMKDYAFENKDHS
KGDFRNYLEKEIYEQHSSLLECLEGRLEALNVYCEIDPEFLENVNEITLCSCGSSYHASLASVYLFERLAKIRARAILAS
EYRYAHFKSNPNELFIAISQSGETADTLEALKLAKAQGLKTISLCNAPFSMMSRISDHVLLIRAGVERSVASTKAFSSQV
MLLWLLSVYLGKQLGTISKEEERIQAKNMLNSVNAMKVEPKLHEKIKRLSKRYLHGHGFFYIGRDVFYPLALEGALKLKE
ISYLHAEGYASAEMKHGPIALVDSNLFTIALLSKHLLFDKTKSNIEELSARDSTICVLSSEILEIADDFIQLEESESYME
EFFRMNLAVQLLALEIAMRLNHDVDHPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=690, Percent_Identity=31.5942028985507, Blast_Score=293, Evalue=3e-79,
Organism=Homo sapiens, GI205277386, Length=688, Percent_Identity=30.2325581395349, Blast_Score=291, Evalue=1e-78,
Organism=Homo sapiens, GI29570798, Length=199, Percent_Identity=28.643216080402, Blast_Score=79, Evalue=2e-14,
Organism=Escherichia coli, GI1790167, Length=615, Percent_Identity=41.7886178861789, Blast_Score=435, Evalue=1e-123,
Organism=Escherichia coli, GI1788651, Length=196, Percent_Identity=27.5510204081633, Blast_Score=77, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17532899, Length=428, Percent_Identity=30.607476635514, Blast_Score=184, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17532897, Length=428, Percent_Identity=30.607476635514, Blast_Score=184, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17539970, Length=428, Percent_Identity=29.4392523364486, Blast_Score=177, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17554892, Length=225, Percent_Identity=26.2222222222222, Blast_Score=66, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322745, Length=376, Percent_Identity=34.0425531914894, Blast_Score=188, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6323731, Length=439, Percent_Identity=26.879271070615, Blast_Score=130, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6323730, Length=209, Percent_Identity=36.8421052631579, Blast_Score=113, Evalue=8e-26,
Organism=Drosophila melanogaster, GI21357745, Length=687, Percent_Identity=29.6943231441048, Blast_Score=280, Evalue=1e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 67031; Mature: 67031

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGYIGDSEKKSILLEGLKELEYRGYDSAGLAVLSNDCLEVFKTQGKLENLKSELKN
CCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCC
KEFLDFGVSIAHTRWATHGKPSSANAHPHFTENLALVHNGIIENHASLKKELENKGHAFL
CHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEH
SQTDTEVIAHLLEETLKSESDLLKAFEKSISLLKGSYAILMLHKRAKESLFYAKSSSPLV
HCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHEEEEHHHHHHHEEEECCCCCEE
VGKGKEGVFFASSLSVLAPKVDQFIILEENSVGQISLENFKDLKHIENMKDYAFENKDHS
EECCCCCEEEECHHHHHCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCC
KGDFRNYLEKEIYEQHSSLLECLEGRLEALNVYCEIDPEFLENVNEITLCSCGSSYHASL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECHHHHCCCCCEEEEECCCHHHHHH
ASVYLFERLAKIRARAILASEYRYAHFKSNPNELFIAISQSGETADTLEALKLAKAQGLK
HHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCC
TISLCNAPFSMMSRISDHVLLIRAGVERSVASTKAFSSQVMLLWLLSVYLGKQLGTISKE
EEEECCCCHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
EERIQAKNMLNSVNAMKVEPKLHEKIKRLSKRYLHGHGFFYIGRDVFYPLALEGALKLKE
HHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHCCHHHHH
ISYLHAEGYASAEMKHGPIALVDSNLFTIALLSKHLLFDKTKSNIEELSARDSTICVLSS
HHHHHCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHH
EILEIADDFIQLEESESYMEEFFRMNLAVQLLALEIAMRLNHDVDHPRNLAKSVTVE
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCC
>Mature Secondary Structure
MCGIVGYIGDSEKKSILLEGLKELEYRGYDSAGLAVLSNDCLEVFKTQGKLENLKSELKN
CCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCC
KEFLDFGVSIAHTRWATHGKPSSANAHPHFTENLALVHNGIIENHASLKKELENKGHAFL
CHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEH
SQTDTEVIAHLLEETLKSESDLLKAFEKSISLLKGSYAILMLHKRAKESLFYAKSSSPLV
HCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHEEEEHHHHHHHEEEECCCCCEE
VGKGKEGVFFASSLSVLAPKVDQFIILEENSVGQISLENFKDLKHIENMKDYAFENKDHS
EECCCCCEEEECHHHHHCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCC
KGDFRNYLEKEIYEQHSSLLECLEGRLEALNVYCEIDPEFLENVNEITLCSCGSSYHASL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECHHHHCCCCCEEEEECCCHHHHHH
ASVYLFERLAKIRARAILASEYRYAHFKSNPNELFIAISQSGETADTLEALKLAKAQGLK
HHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCC
TISLCNAPFSMMSRISDHVLLIRAGVERSVASTKAFSSQVMLLWLLSVYLGKQLGTISKE
EEEECCCCHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
EERIQAKNMLNSVNAMKVEPKLHEKIKRLSKRYLHGHGFFYIGRDVFYPLALEGALKLKE
HHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHCCHHHHH
ISYLHAEGYASAEMKHGPIALVDSNLFTIALLSKHLLFDKTKSNIEELSARDSTICVLSS
HHHHHCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHH
EILEIADDFIQLEESESYMEEFFRMNLAVQLLALEIAMRLNHDVDHPRNLAKSVTVE
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]