Click here to switch to the map view.

The map label for this gene is fabZ [H]

Identifier: 108563747

GI number: 108563747

Start: 1369239

End: 1369718

Strand: Reverse

Name: fabZ [H]

Synonym: HPAG1_1322

Alternate gene names: 108563747

Gene position: 1369718-1369239 (Counterclockwise)

Preceding gene: 161984736

Following gene: 108563746

Centisome position: 85.8

GC content: 41.04

Gene sequence:

>480_bases
ATGGAACAAAGCCATCAAAACTTACAATCTCAATTTTTTATAGAGCATATCTTACAAATTCTACCTCACCGCTATCCCAT
GCTCTTAGTGGATAGAATTATAGAATTACAAGCCAATAAAAAAATTGCCGCTTATAAGAATATCACTTTTAATGAAGACG
TGTTTAATGGGCATTTCCCTAATAAGCCCATTTTCCCGGGCGTTTTGATCGTAGAGGGCATGGCGCAAAGCGGAGGGTTT
TTAGCTTTCACTAGCTTGTGGGGGTTTGACCCTGAAATAGCCAAAACAAAAATCGTGTATTTCATGACGATTGATAAGGT
TAAATTCCGCATTCCTGTAACCCCAGGCGACAGATTAGAATACCATTTAGAAGTCTTAAAGCATAAGGGCATGATCTGGC
AAGTGGGCGGCACGGCTCAAGTGGATGGCAAAGTGGTCGCTGAAGCCGAATTAAAAGCCATGATCGCAGAGAGAGAATAA

Upstream 100 bases:

>100_bases
CAAGCGAGCGGTTTTCTTATGGTATAATAGCGGTTATTTTTTAGAATAACCAACGCTAAAAATGGCGCTTTAATTGAATC
CAAAACAAGGAGTTTATTTT

Downstream 100 bases:

>100_bases
AAATGAGTAAGATTGCAAAAACAGCCATTATCTCTCCTAAAGCAGAGATTAATAAGGGCGTAGAGATTGGGGAATTTTGC
GTGATTGGAGATGGCGTCAA

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MEQSHQNLQSQFFIEHILQILPHRYPMLLVDRIIELQANKKIAAYKNITFNEDVFNGHFPNKPIFPGVLIVEGMAQSGGF
LAFTSLWGFDPEIAKTKIVYFMTIDKVKFRIPVTPGDRLEYHLEVLKHKGMIWQVGGTAQVDGKVVAEAELKAMIAERE

Sequences:

>Translated_159_residues
MEQSHQNLQSQFFIEHILQILPHRYPMLLVDRIIELQANKKIAAYKNITFNEDVFNGHFPNKPIFPGVLIVEGMAQSGGF
LAFTSLWGFDPEIAKTKIVYFMTIDKVKFRIPVTPGDRLEYHLEVLKHKGMIWQVGGTAQVDGKVVAEAELKAMIAERE
>Mature_159_residues
MEQSHQNLQSQFFIEHILQILPHRYPMLLVDRIIELQANKKIAAYKNITFNEDVFNGHFPNKPIFPGVLIVEGMAQSGGF
LAFTSLWGFDPEIAKTKIVYFMTIDKVKFRIPVTPGDRLEYHLEVLKHKGMIWQVGGTAQVDGKVVAEAELKAMIAERE

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=138, Percent_Identity=46.3768115942029, Blast_Score=133, Evalue=7e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 18168; Mature: 18168

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQSHQNLQSQFFIEHILQILPHRYPMLLVDRIIELQANKKIAAYKNITFNEDVFNGHFP
CCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCC
NKPIFPGVLIVEGMAQSGGFLAFTSLWGFDPEIAKTKIVYFMTIDKVKFRIPVTPGDRLE
CCCCCCCEEEEECCCCCCCEEEEEECCCCCCCHHCEEEEEEEEEEEEEEEEECCCCCHHH
YHLEVLKHKGMIWQVGGTAQVDGKVVAEAELKAMIAERE
HHHHHHHHCCEEEEECCCEEECCEEEEHHHHHHHHHCCC
>Mature Secondary Structure
MEQSHQNLQSQFFIEHILQILPHRYPMLLVDRIIELQANKKIAAYKNITFNEDVFNGHFP
CCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCC
NKPIFPGVLIVEGMAQSGGFLAFTSLWGFDPEIAKTKIVYFMTIDKVKFRIPVTPGDRLE
CCCCCCCEEEEECCCCCCCEEEEEECCCCCCCHHCEEEEEEEEEEEEEEEEECCCCCHHH
YHLEVLKHKGMIWQVGGTAQVDGKVVAEAELKAMIAERE
HHHHHHHHCCEEEEECCCEEECCEEEEHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA